Human Growth Hormone for IVF???
MandaS08
member
My RE is recommending that we use human growth hormone (hgh)(brand name Saizen) on our next IVF cycle.
I've done some reseach and it seems like primarily this is used in women over 40 to help with egg quality-I'm 31.
Also, this is going to add around $1500 on to our meds....thoughts? I know I need to do some more research but I thought I would ask here first.
Has anyone else used this?
TTC since 5/2010
DX with Diminished Ovarian Reserve - AMH of 1.1 - 7/2011; AMH of .42 8/2012BFP 9/1/10-M/C confirmed 9/8/10-Methotrexate 10/6/10
IUI #1 (w/clomid)-9/5/11-BFN ; IUI #2 (w/clomid)-10/5/11 - BFP - 11/1/12-No sac seen; 11/2/11 and 11/9/11-Methotrexate
IVF #1- ER 2/2; ET 2/5;-Two 8 cell embryos transfered = BFFN
Surprise BFP - 5/7/12
U/S on 6/8/12 - H/B at 128 BPM; U/S on 6/14/12 @ 9wks-No H/B-D&C on 6/17/12
IVF 2.0- ER 10/17; ET 10/20-One 12 cell, one 10 cell and one 8 cell embryo transfered
BFP! 11/16/12 U/S- Two nuggets with perfect heartbeats! EDD 7/10/13
5/31/2013- My miracles arrived at 34w2d! Welcome to the world Harper and Nolan!
My Blog- http://waitingonaangel.wordpress.com/
Re: Human Growth Hormone for IVF???
I used HGH on my last cycle. My RE said she likes her patients that have had a failed cycle or are over 35 to use HGH to help with egg quality.
I used a different brand, Omnitrope, and did the shots every other day.
I don't know if it helped or not. It was a new RE and also a new med. I don't know what was the magic ticket, but something worked, even when my odds weren't good.
How was your egg/embryo quality for your last cycle? HGH was expensive and it stung like helll!!! But if it helped at all, it was worth it for me!
Good luck!!
2/06 - surprise pregnancy - twins
3/06 - m/c 1st baby at 6 weeks
5/06 -2nd baby had no heartbeat at 14 wks.
D&E - Bled out. Blood transfusions. Week in ICU - Cheated Death!
Diagnosis: Blood clotting and bleeding disorder, immune issues, & cervical stenosis
5/10 - 1st IVF cycle - BFN
FET - 10/12/10 - BFN
1/11 - IVF with PGD - BFN
IVF - May - BFN
6/11 New RE - fingers crossed!
9/11 - IVF - 4 transferred
10/13 - BFP!!
It's a boy! Clint Michael, Due in June!!!
We used Tev-Tropin for two cycles. Obviously, we didn't have success, but I don't regret trying it. There are some studies which show a positive correlation between HGH and egg quality, though its use remains open to debate.
If a cycle is successful, you'll never know what did the trick. Our thinking was that with DOR, it was highly likely that we have a quality issue. (The consensus is that a DOR diagnosis goes hand in hand with egg quality issues, regardless of age.). And, in the grand scheme of things, we didn't think an additional $1500 was a big deal especially given the possible benefits. GL!
Baby boy Henry born 2015.
Expecting our capstone baby (boy) early March 2018.
Out of 8 eggs, 5 fertilized, but only 2 of those embryo's were any good. This very well might be our last shot at IVF with our OE, so we'll most likely do it-I would hate to wonder what if.
TTC since 5/2010
DX with Diminished Ovarian Reserve - AMH of 1.1 - 7/2011; AMH of .42 8/2012BFP 9/1/10-M/C confirmed 9/8/10-Methotrexate 10/6/10
IUI #1 (w/clomid)-9/5/11-BFN ; IUI #2 (w/clomid)-10/5/11 - BFP - 11/1/12-No sac seen; 11/2/11 and 11/9/11-Methotrexate
IVF #1- ER 2/2; ET 2/5;-Two 8 cell embryos transfered = BFFN
Surprise BFP - 5/7/12
U/S on 6/8/12 - H/B at 128 BPM; U/S on 6/14/12 @ 9wks-No H/B-D&C on 6/17/12
IVF 2.0- ER 10/17; ET 10/20-One 12 cell, one 10 cell and one 8 cell embryo transfered
BFP! 11/16/12 U/S- Two nuggets with perfect heartbeats! EDD 7/10/13
5/31/2013- My miracles arrived at 34w2d! Welcome to the world Harper and Nolan!
My Blog- http://waitingonaangel.wordpress.com/
I used Tev-Tropin during my cycles. Just a different brand of HGH. When I was using it, I could get it at $350 per vial if I purchased them all at one time (it was cheaper than Saizen at that time). So, it added $1,050 to our meds cost. I was 32 the first time I used it and 33 the last time.
Good luck! I really hope it makes a difference for you!
~SAIF/PAIF/Everyone Welcome~
Me= 37 and DH = 41
Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)
IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN
IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.
IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132. Lil is here!
TTC#2: Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.
IVF #4: BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN
IVF #5: MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN
IVF #6: (New RE): Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN
FET#1: BFN
3 failed IVF with OE and 2 failed frozen DE cycles
Last fresh hail mary DE cycle starting Feb 2013
PAIF/SAIF always welcome