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Menopur :/

crt0323crt0323 member
in Infertility

Tonight was the first night of stims for IVF #2. I'm on gonal-f and menopur this time. The menopur burned so bad! I wasn't anticipating that. Now, less than 10 minutes later, I'm having mild cramping. Anyone experience this with menopur? 

Me- 26 DH-32
TTC since August 2010
Unexplained Infertility
5 rounds of clomid and 4 rounds of tamoxifen = BFN
IUI #1 - Jan 2012 with Tamoxifen - BFN IUI #2 - Feb 2012 Cancelled :(
IVF #1- May 2012: BFP on 05/29/12!! 06/01 Beta #1= 122 06/04 Beta #2 74 :( - C/P
06/07/12 = BFN Moving onto IVF #2 August 2012
22 retrieved, 13 fertilized, none to freeze
Transferred two embies on 08/19. Beta 1 is 08/31 Beta #1-122 Beta #2- 541
1st U/S 09/12- 1 sac!
Praying this is my take home baby!
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Re: Menopur :/

  • AmCheriAmCheri member
    Menopur treated me very poorly.  The only thing that helped somewhat with the wicked burning was icing beforehand.  I'm so sorry you're hurting.  Can't help with the cramping -- I don't recall experiencing that.  Hugs and feel better.  
    Baby girl Lila born 2013.
    Baby boy Henry born 2015.
    Expecting our capstone baby (boy) early March 2018.
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  • stephwp1stephwp1
    Menopur is not my friend.  I mixed my Gonal F with the Menopur so I only had to do one injection.  It did seem to cut down on the burning somewhat.  I think the Gonal F diluted it a bit.  Ask your RE if you can mix.
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  • KdgTeacherKdgTeacher member

    I'm zero help, but can I just say I totally wimpered when I read this.  I'm doing 1 vial of Menopur/day for my upcoming IVF and to hear it burns so bad isn't what I wanted to hear!!!!

    Hope the cramping goes away!

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  • HawkJrHawkJr member
    Menopur burned me only when I injected it too fast. Now this last cycle I was on Repronex and it was horrible!!! I never got cramping.
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  • CutieGirlLissieCutieGirlLissie member

    I hear ya!! I am mixing Menopur and Bravelle this time around (last time was just Menopur) and it seems to sting a little less. Not sure if any of this will help you but here are some tips that worked for me:

    1. My right side hurt less (i know there's no rhyme or reason, it just did).

    2. Inject slow and steady, the faster it went in the more it burned.

    3. Make sure you are putting the needle in at 90 degrees. DH gave me all my sots and it wasn't until the 4th day that he was re-reading the directions and said "huh, the directions say 90 degrees and I've been doing 45 degrees this whole time". I swear it felt a million times better from that night on! 

    Good luck! 

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  • Maybe JoleisaMaybe Joleisa member
    The only time my Menopur shot burned was when I administered it too soon after swabbing (with alcohol) the spot I was going to stick myself. Once I made certain the swabbed spot was totally dry--I felt nothing.

    image
    TTC since 10/2010
    IUIs # 1-5 = BFFN
    IVF # 1(July 2012) = BFN
    IVF # 2 (November 2012) = BFP (MIssed MC D&C @ 8w3d on 1/10/13)
    IVF # 3 (June 2013) = BFN 
    IVF # 4 (September 2013) = BFP Fraternal twin boys! (Loss at 21w6d due to IC on 1/26/14...devastated.)
    3/21/14--TAC (transabdominal cerclage) w/Dr. Davis in NJ
    IVF # 5 (May 2014) = BFN
    FET (August 2014) = BFN

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  • jekomojekomo
    I found that if you mix it and then let it sit for five or ten minutes, it does take a little of the sting out. Good luck!
    Age 37
    TTC Since August 2010
    Husband SA Feb. 2011 normal
    HSG Feb. 2011, clear
    Clomid April, May & June 2011, unmonitored
    First visit to RE July 2011
    Sonohystogram Aug 2011 normal
    Sept 2011 AMH test in normal range
    Sept 2011 Clomid cycle, monitored + TI = BFN
    Oct 2011 Clomid + IUI = BFN
    Long break -- tried on our own
    IVF #1 June/July 2012 = 4 retrieved, 2 fertilized and transferred, BFP, chemical
    IVF #2 Sept/Oct 2012 = cancelled due to poor response to EPP with Follistim (300), Menopur (150), and Lupron (10) Image and video hosting by TinyPic
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  • lalee73lalee73 member

    I agree with most everyone menopur does burn, but if you let the alcohol dry and then push slowly but steadily it helps a lot!

    GL! 

    Me 38, DB 38. Unexplained infertility. TTC 3 years. 3 failed IUI's. IVF #1 5-20. 3 embies transferred day 3. First beta 5-31. BFN. IVF#2 ER 7-31. 3 embies transferred day 3. Beta 1=144. beta #2=527. beta#3 3027. US: 1 perfect heartbeat at 156!
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  • Laurakat81Laurakat81 member
    I did Menopur last cycle and I only felt the tiniest burning sensation for maybe 5 seconds. As for the cramping, I'd take it as a sign that its already getting your ovaries working hard! Good luck!

    [spoiler] My Blog: Grow Baby Grow

    BFP #1: 12/2009 m/c 1/2010 BFP #2: 6/2010 m/c 8/2010

    BFP #3: 10/2011 ectopic 11/2011 (right tube removed, learned left tube was probably nonfunctional due to scar tissue from infection after m/c)

    3 failed IUIs, IVF #1: 18R, 12M, 10F, 3 poor quality 5d embryos transferred= BFP #4!!!!!

    Betas: 9dp5dt: 64 ~14dp5dt: 91 (expecting miscarriage, doubling time of 236 hours) ~16dp5dt: 200~18dp5dt: 500

    First Ultrasound at 6w2d revealed two sacs, only one with a heartbeat

    LK arrived after 42 weeks on August 14, 2013! Beautiful, healthy, and happy!

    TTC#2: IVF booked for April 2015

    Surprise BFP#5 February 19, 2015 EDD: November 2, 2015

    Betas: 10dpo: 10, 14dpo: 77, 17dpo: 270

    First Ultrasound at 5w1d showed a miracle UTE baby! And right ovary ovulation to left fallopian tube.

    JD arrived at 38 weeks on October 20, 2015.

    TTC #3: Since October 2017. BFP #6 July 2, 2018 EDD: March 16, 2019 [/spoiler]


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  • BellaLuxBellaLux member
    Yikes! Next month I'll be stiming with Menopur and Follistim. I'll keep this is mind (allowing swab to dry and injecting slowly). Thanks ladies!

    ~TTC#1 Since July 2011~ 
    Dx: Fibroids & Tubal Infertility
                                                        9/12 -IVF#1 =BFN; 5/14 -IVF#2=BFP:-) EDD 2.19.2015                                                

    S/PAIF Welcome 





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  • megs3084megs3084 member
    I start menopur & follistim at the end of the month, Im glad this thread popped up.  Thanks for the tips!
    "Everything will be alright in the end. So if it's not alright, it is not yet the end."
    Me:29 DH:29  TTC since 1/11 Dx: unexplained IF/early DOR/immune issues 
    Feb'12- July'12-testing(all clear minus slight arcuate ute), 3 IUI with clomid all BFN
    8/30IVF#1 Antagonist protocol- ER 9/11-8R, 7M, 5F. 
    ET 9/14 2 embies transferred. 1 10cell Grade 4, 1 8cell Grade 4. No frosties. BFN
    IVF#2 Antagonist protocol plus baby aspirin- ER 12/5-16R, 12M, 8F!
    ET 12/10 5dt! 1 fully expanded blast & 1 early blast. No frosties. BFN
    3/13 hysteroscopy & polypectomy, Consulted w Dr. Kwak-Kim.  
    DX: High NK cells, cytokines, DHEAs& PAI1;  hypothyroid, +APA, restricted bloodflow
    7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle
    (plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim)
    ER 7/19 14R, 11M, 9F(4 natural fert, 5 with ICSI)
    ET 5dt 7/24 2 fully expanded blasts.  SURPRISE 3 FROSTIES!!!
    Beta #1 8/2 335!!!! Beta #2 829!!!  1st u/s 8/14 showed TWINS!!!!!
    11/11: TEAM PURPLE!!!!!
    3/21/14-L&W born at 37w via csection
    Here Comes the Sun Blog
    PAIF/SAIF welcome!
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  • Native+GirlNative+Girl member

    My experience hasn't been too bad with Menopur. It does burn a bit, but I just go slow. Also, letting it sit in the syringe for a few minutes seems to help. And like PP said, for whatever reason, my right side doesn't burn as much as my left.

    I did have to double up on my Menopur this cycle, mixed two vials with 1ml of solution. That sucked.

    Ganirelix has been my least favorite injection by far. Dull needle, burns, and itches. No, thanks!

    **PAIF/SAIF Welcome**
    TTC #1 March 2010 - Nov 2012
    Me: 29, PCOS (anov), Hashimoto's Disease // DH: 30, normal SA
    3 Clomid, 1 Clomid/Menopur, 1 Menopur w/ TI (CX 4x's due to cysts) - All BFN
    1 Clomid/Menopur, 2 Menopur, 1 Follistim w/ IUI - All BFN
    RPL & Karyotype testing normal

    IUI #5 (12/1/12) --> Follistim + 1/3 hCG Trigger = BFP! EDD: 8/23/13
    Betas --> 61 (13dpo) // 156 (16 dpo) // 223 (18dpo) // 656 (21 dpo)
    U/S --> 5w0d - sac seen // 6w0d - hb detected // 7w0d - hb seen and heard, measuring 6w6d!
    8w6d - wiggly baby! // 9w3d - wiggly baby with fingers!

    Baby boy born 8/24/13

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      My Blog: Searching for Lucky Socks

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  • liz4pawsliz4paws member

    imageHawkJr:
    Menopur burned me only when I injected it too fast. Now this last cycle I was on Repronex and it was horrible!!! I never got cramping.

    Me too. I was really scared because of all of the stories of it burning, but I went slow and it didn't burn at all. I didn't even ice first. GL!

    ************ Signature/Ticker Warning ************
     Me (32) DH (36) - Finding our way to baby #1
     Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
     DH: Severe MFI

     12/2/11 - IUI #1- BFN 
    8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)
    My ovaries are just for decoration

     12/6/12 - Adopted five embryos that had been frozen for over ten years!
     2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
     2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
     3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

    6/5/13 - Adopted four new embryos that had been frozen for seven years!      
    9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
    9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
     9/29/13 - m/c @ 5w1d. :(

    11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
     11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
    Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
    6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

    Snowflake baby is a girl! 
    Our beautiful Snowflake girl arrived on July 22, 2014!   
     My embryo adoption blog: Wishing on a Snowflake
      
        image      image 
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  • Bethany1026Bethany1026
    Ugh...I have been doing it twice a day... it is terrible, burns like hella!!!
    Anniversary
    TTC #1 since 3/10:
    DX: Me-PCOS, retroverted/ tilted ute - DH- MFI, DH-4 mo of Clomid therapy= no improvement. Weekly HCG injections.
    Me-34, DH-33
    HSG- unsuccessful, SHSG (dialated)-no blockages
    7/11-Clomid (unmonitored) BFN,
    #1 Fresh IVF 9/11: w/ ICSI & AH (only option): (1 transfered, 8BF) = BFN!!
    #2 FET: 2 transferred (2 6BF) 12/11 = BFFN!!
    Surprise + HPT on break! 2/12 Beta 1: 6 Beta 2: <5 = c/p ( RE had given me provera... So pretty sure this ruined everything)<BR> #3 Fresh IVF 3/12: w/ ICSI & AH (2 transfered 8BF & 7BF, 1 to freeze) = BFMFN!
    New RE 5/12
    6/14 Hysteroscopy
    #4 Fresh IVF 8/12: 5dt of 2 5AB blasts = BFN!... what else is new?!?
    New RE insists its a transfer issue, immunology checked & good
    #5 IVF FET 1/13 under anesthesia : Two 5 day blasts transferred
    + HPT!! Beta1: 2315 Beta2: 6442 Beta3: 31,061
    First u/s 1/30/13: Shows 1 healthy heartbeat!!

    Was he was right? I wasted 4 IVF's and the doctors were not getting the catheter in?!?
    ~~ Bump Bestie/ IRL Lynn0926 ~~
    BabyFruit Ticker
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