Infertility

My RE said the worst part of IVF is....

Progesterone shots!!

She says that's the number one thing she gets complaints about and they are especially bad for 'someone so skinny'. She did say that if I can't take it, she will switch me to vag supps, but they're more expensive. She does the shots with all OOP ladies to help keep costs down.

I can't imagine that progesterone shots are the worst part about IVF... Not after all the horror stories I've heard. So ladies, what really is the worst part about IVF? 

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Re: My RE said the worst part of IVF is....

  • I think the worst part is the emotional and financial outlay without any guarantees.  It's the unknown... if you could be told it would be worth it all in the end, it would be a different story.

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  • imageXV11Star:

    I think the worst part is the emotional and financial outlay without any guarantees.  It's the unknown... if you could be told it would be worth it all in the end, it would be a different story.

    I agree with the above. The cost is the worst, but I am on my 3rd and I am just so tired of it all. Every u/s follie check just made me so sad and stressed.

    I do hate PIO, but it is so much cheaper. I prefer it really anyway. It's just another shot. Heating pad will help.

    PAIF and SAIF Always Welcome!
    TTC since 2007
    6 IUIs, 3 IVFs, and 2 m/c :< PCOS, Blood Clotting Disorder & MFI
    IVF #2 Aug 2011 is a BFN:<
    IVF #3 March 2012 is a BFN
    Not sure what to do now. Sad and lost.
    Lilypie Angel and Memorial tickers Lilypie Angel and Memorial tickers
  • The financial part certainly is hard.  The emotional part has been really hard too.  The whole thing is such a roller coaster.  You can't plan anything and don't know when anything is going to happen until 2 days before.  We're talking monitoring appts, ER, ET.  I still haven't heard if I have any snow babies (My ET was Sunday).  The whole thing is one waiting game right after another.

    But for me, the worst part has been the OHSS that I've already developed.  I really didn't know how I was going to make it through yesterday.  I don't think I've ever felt so much pain in my entire body.  It was also day 7 of pain so it's certainly getting old.  I know everyone (or most) don't get OHSS and thank God for that.  I'll leave out the fun details but I'm hoping once I get my BFP that I'll forget what a hard experience this has been. 

    Also, I'm OOP and my RE gave me the choice of PIO or Crinone.  I chose Crinone.  The cost just kinda blended in with everything else.  Stick out tongue


    After more than 2 years of fertility treatments, FET did the trick!
    IVF March 2012 - BFP! - Severe OHSS = 8 days in the hospital in kidney failure
    No heartbeat at 10w6d
    FET August 27,2012 = BFP!
    It's a boy!
    My Blog - 3 Dogs, No Baby

    image
    BabyFruit Ticker
  • Have not done IVF yet, but check with your insurer on the Crinone.  I have no coverage at all for fertility medications, but my insurer covered the Crinone as it has uses other than fertility. 

    image
    DOR and AMA
    2/12-5/12: 4 IUI cycles = all BFN;
    7/12: DE IVF # 1 (with ICSI)- 20R, 16M, 14F, 5DT of 2 blasts; 6 frosties = BFN;
    Lupus anticoagulant initially high, then found to be normal on hematology consult;
    Follow up testing in September all clear;
    Started synthroid for "high normal" TSH;
    FET # 1- late October 2012- BFP on FRER; beta # 1- 21(low), beta # 2- 48 (still low), beta # 3- 132, beta # 4- 1,293; beta # 5- 5,606; last beta- over 100,000. First u/s 11/21- heard heartbeat
    12/12- Officially an OB patient!
    Level 2 ultrasound at 20 weeks shows vasa previa and VCI
    Referral to MFM and mandatory c section for delivery
    Beautiful baby girl born at 34 weeks
    Finally home after 15 day NICU stay!
    Trying for sibling: FET # 2- May 2014; beta 5/31, BFN
    FET #3, early July 2014; beta 7/14, BFN
    DE IVF # 2- August 2014; 14R, 13M, 11F, 5dt of 2 blasts (3 AA), 5 frosties = BFN
    FET #4- December 2014, yet another BFN

    Dr. KK work up shows borderline uterine blood flow, elevated NK cells, and MTHFR mutation (homozygous for c677t)

    Added baby aspirin, prednisone, supplements, Metanx, and intralipids

    Switched to large clinic for final attempt; had endometrial receptivity testing in January; FET March 2015 = yet another BFN

    Likely OAD- NBC

  • imageXV11Star:

    I think the worst part is the emotional and financial outlay without any guarantees.  It's the unknown... if you could be told it would be worth it all in the end, it would be a different story.

    I completely agree. Unfortunately I think there's still this misconception that "if you try long enough, you'll eventually get success" and while that might be true to some extent the probability doesn't increase each time, if anything it likely decreases. 

    It also negates the fact we're human and at some point want other things to live for in life than the unpredictability of IF. 

    (Live in Europe) TTC since 1/2010
  • imageXV11Star:

    I think the worst part is the emotional and financial outlay without any guarantees.  It's the unknown... if you could be told it would be worth it all in the end, it would be a different story.

     

    This.  

    -LJ
    Baby Birthday Ticker Ticker
    BabyFruit Ticker
  • Definitely the emotional part. I suffer from depression as it is. This whole experience has brought out emotions that I didn't know existed.
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  • Our RE nurse told us most women are really nervous about the PIO shots and then come back and say they weren't nearly as bad as they'd thought. I totally agree with that. I also agree that the emotions are the hardest. For me, the thought that so many people can have children anytime they choose while I may never be able to because I can't afford to get PG is hard for me make peace with.

    Me 30/DH 31 Married in June 2003. TTC since 2008. M/c in Nov. 2008. D/x: DOR and MFI 5 cycles of IUI in 2010. IVF #1 in Nov. 2011. ER 11/22. ET 11/25. BFN.
  • imageXV11Star:

    I think the worst part is the emotional and financial outlay without any guarantees.  It's the unknown... if you could be told it would be worth it all in the end, it would be a different story.

    Yes

    If you do the PIO right it's not so bad.  Yes, I am sore but it's so worth it.  Just make sure you ice before, have DH inject very slow, masssage the area when he is done and use heating pad for about 10 minutes after.  You can do it!!! Good luck!

    image
    After 6 long years of TTC and a traumatic birth... I finally got to hold my baby in my arms!

    'Delight yourself in the LORD and he will give you the desires of your heart.'Psalm 37:4

    2006 start TTC

    2007 Start w/ RE (Endo and MFI previous marriage)/ 2008 Vericocele surgery/3 clomid cycles
    2009 Lap removed stage III endo/ 2 failed IUI/ Divorce

    2011 Remarried
    October 2011 Dx: Endo & DOR/ November 2011- clomid & TI cycle
    January 2012 IVF~  Flare protocol 10 ER/ 9 mature fertilized with ICSI/ ET- 2 Grade A Blasts/ 4 frozen= BFN
    Febuary 2012- -Endo Biopsy/  MTHFR diagnosis
    March 8- FET 2 grade A blasts= BFP!!!!

    November 2012-  Charles was born by emergency C-Section

    Dealing with:
    Stage III Endo/ DOR/ MTHFR two mutations C677T & A1298C

    Currently TTC #2  FET planned January 2014

  • Emotional part is definitely hard, I am a HUGE wimp when it comes to needles (definitely my worst part!)..my first IVF I handled the needles pretty well, but was scared of PIO so I did Crinone.  I feel that this round I have become way more sensitive and all the needles blow big time.  I probably am the only one who prefers the vag supps over the PIO...but my RE wants me to do the PIO again (I did them for my FET).  The first week wasn't bad...but after that I got really sore.  GL
    Anniversary
    TTC #1 since 3/10:
    DX: Me-PCOS, retroverted/ tilted ute - DH- MFI, DH-4 mo of Clomid therapy= no improvement. Weekly HCG injections.
    Me-34, DH-33
    HSG- unsuccessful, SHSG (dialated)-no blockages
    7/11-Clomid (unmonitored) BFN,
    #1 Fresh IVF 9/11: w/ ICSI & AH (only option): (1 transfered, 8BF) = BFN!!
    #2 FET: 2 transferred (2 6BF) 12/11 = BFFN!!
    Surprise + HPT on break! 2/12 Beta 1: 6 Beta 2: <5 = c/p ( RE had given me provera... So pretty sure this ruined everything)<BR> #3 Fresh IVF 3/12: w/ ICSI & AH (2 transfered 8BF & 7BF, 1 to freeze) = BFMFN!
    New RE 5/12
    6/14 Hysteroscopy
    #4 Fresh IVF 8/12: 5dt of 2 5AB blasts = BFN!... what else is new?!?
    New RE insists its a transfer issue, immunology checked & good
    #5 IVF FET 1/13 under anesthesia : Two 5 day blasts transferred
    + HPT!! Beta1: 2315 Beta2: 6442 Beta3: 31,061
    First u/s 1/30/13: Shows 1 healthy heartbeat!!

    Was he was right? I wasted 4 IVF's and the doctors were not getting the catheter in?!?
    ~~ Bump Bestie/ IRL Lynn0926 ~~
    BabyFruit Ticker
  • The PIO is the worst shot of the IVF process, but totally doable and not as bad as I expected.

    For me the worst part of IVF is the cost with absolutely no guarantee-if you're out of pocket its almost sickening at the amount of money you spend, and may still get nothing in return (like my first cycle).  If I'm successful eventually it will all be worth it-but there is no guarantee that I will.

    TTC since 5/2010
    DX with Diminished Ovarian Reserve - AMH of 1.1 - 7/2011; AMH of .42 8/2012
    BFP 9/1/10-M/C confirmed 9/8/10-Methotrexate 10/6/10
    IUI #1 (w/clomid)-9/5/11-BFN ; IUI #2 (w/clomid)-10/5/11 - BFP - 11/1/12-No sac seen; 11/2/11 and 11/9/11-Methotrexate 
    IVF #1- ER 2/2; ET 2/5;-Two 8 cell embryos transfered = BFFN
    Surprise BFP - 5/7/12
    U/S on 6/8/12 - H/B at 128 BPM; U/S on 6/14/12 @ 9wks-No H/B-D&C on 6/17/12
    IVF 2.0- ER 10/17; ET 10/20-One 12 cell, one 10 cell and one 8 cell embryo transfered
    BFP!   11/16/12 U/S- Two nuggets with perfect heartbeats! EDD 7/10/13

     

    5/31/2013- My miracles arrived at 34w2d!  Welcome to the world Harper and Nolan!Lilypie First Birthday tickers

    My Blog- http://waitingonaangel.wordpress.com/

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  • imageXV11Star:

    I think the worst part is the emotional and financial outlay without any guarantees.  It's the unknown... if you could be told it would be worth it all in the end, it would be a different story.

    I completely agree with this.  I have yet to go through an IVF cycle. I start stims for my first cycle on the 6th. But this has been the most difficult part. And side note. My CRNP said that most people in the office I go to complain more about the drinking 32 oz of water and holding it for the Mock then the injections. (But I'm sure I'll disagree...)

  • Sigh. My thoughts EXACTLY
    imageimage

    TTC#1 since October 2010

    "The jump is so frightening between where I am and where I want to be...because of all I may become I will close my eyes and leap." Mary Anne Radmacher

    Me:35, 5 major abdominal surgeries for Ulcerative colitis, failed j pouch, perm. Ileostomy DX-DOR & Tubal abnormalities/Extensive Adhesions from earlier surgeries.latest fsh -26 :(

    IVF 1- March 2012 Antagonist Protocol; BCP until March 3; AFC this cycle is 10 (Hooray); Start stims on March 9; ER on March 19- 2R; 2T (1 perfect 8 cell, 1 scrappy 3 cell); tubal infection from ER-hospitalized. Doomed! BFN

    Essure Procedure to treat bilateral hydrosalpinx; June 2012, wait 3 months for confirmation test.

    IVF2 (Egg Banking)-letrozole/antagonist cycle; June/July 2012 225iu merional + cetrotide; slow responder, Ovulated before ER. Unbelievable. Canceled remaining cycles with my eggs

    DE IVF in Brno, Czech. Approx. ET on Oct 6 CANCELLED-Essure didn't close both tubes-test again in 3 months

    IVF3-DE IVF ET on Dec 9, 2012 (decided to roll the dice no matter what!)

    2 perfect HB transferred; 8dp5dt beta:36; 10dp5dt beta 15; chemical pregnancy.

    Turning our hearts toward adoption

    DH:36, SA-perfect

    Married since July 11, 2009

    Fur baby Cairn Terrier

    SAIF/PAIF Welcome

  • If he means stricly physically, the worst is the discomfort of OHSS. Second progesterone shots.
  • imageHappyIAm:
    imageXV11Star:

    I think the worst part is the emotional and financial outlay without any guarantees.  It's the unknown... if you could be told it would be worth it all in the end, it would be a different story.

    Yes

    If you do the PIO right it's not so bad.  Yes, I am sore but it's so worth it.  Just make sure you ice before, have DH inject very slow, masssage the area when he is done and use heating pad for about 10 minutes after.  You can do it!!! Good luck!

    I completely agree with XV11Star.  The worst part is the uncertainty and unknown.  But honestly, for me, PIO sucks bigtime.  I feel like limping as I walk around... and I do the heat, massage...  my haunches still hurt like hell!  And it seems to get worse as I go - it's kind of cumulative.  I much preferred the Prometrium supps, which I didn't really mind. 

    Severe MFI. Me: supposedly all clear but eggs showed vacuoles.

    IVF #1 January 2012, ER Jan 14th: 34R, 27M, 23F. Day 3: 18 embies still strong. Day 5: zero "good," one "fair," the rest "poor." Transferred 3. None made it to blast or to freeze. Jan 28: BFN.

    Lucky IVF #2: Transferred two beautiful day three embies on St. Patrick's Day. BFP on HPT 7dp3dt. Beta 1 (14dpER)=106; Beta 2 (16dpER)=140; Beta 3 (19dpER)=264! First u/s 4.17.

    imageimageimageBabyFruit Ticker

    Hope is the thing with feathers - that perches in the soul - and sings the tune without the words - and never stops - at all - (Emily Dickinson)

  • imageMitzi Bishi:
    imageXV11Star:

    I think the worst part is the emotional and financial outlay without any guarantees.  It's the unknown... if you could be told it would be worth it all in the end, it would be a different story.

    I completely agree. Unfortunately I think there's still this misconception that "if you try long enough, you'll eventually get success" and while that might be true to some extent the probability doesn't increase each time, if anything it likely decreases. 

    It also negates the fact we're human and at some point want other things to live for in life than the unpredictability of IF. 

    I agree with these ladies. The worst part of IVF is when it doesn't work. I can handle the rest just fine if it had a different ending.

    TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
    DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
    5 IUI's: 2/11 to 6/11 and 1/12= BFN
    OE IVF#1-4 8/11-6/12= all BFN
    DE IVF#1 11/12 bad embryos= BFN
    DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
    CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
    DE IVF #3 1/14  ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d

    DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
    First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!

    K & K born 11/21/14 at 38wks 4 days

    imageimage

    SAIF/PAIF Welcome


    http://waitingforraintostop.wordpress.com

  • imageMrs.McIrish:
    imageMitzi Bishi:
    imageXV11Star:

    I think the worst part is the emotional and financial outlay without any guarantees.  It's the unknown... if you could be told it would be worth it all in the end, it would be a different story.

    I completely agree. Unfortunately I think there's still this misconception that "if you try long enough, you'll eventually get success" and while that might be true to some extent the probability doesn't increase each time, if anything it likely decreases. 

    It also negates the fact we're human and at some point want other things to live for in life than the unpredictability of IF. 

    I agree with these ladies. The worst part of IVF is when it doesn't work. I can handle the rest just fine if it had a different ending.

    This is exactly how I feel as well. :(   Its hard to keep going when nothing seems to work for you. 

     TTC #1 since 6/09
    Dx: PCOS and MFI
    3 IUIs, 4 IVFs = BFFN
      3rd RE: IVF #5/FET = BFP
    14dp5dt=1170 16dp5dt=2573

    1st u/s=
    TWINS!
    It's a Boy and a Girl!

    Born at 34w3d! 
     

  • I think the emotional part is the worst part. We have been TTC for over 3 years. Month after month of AF has been aweful! Some of my friend are on baby # 2 and started TTC after us.

    We are going to be using Crinone starting tomorrow. I hate needles and I am glad I don't have any more for a long time.

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  • Physically I was the most afraid of PIO but our clinic doesn't even use it anymore so we use supplements instead.

    I would have looked into IVF sooner if I had known this about PIO.

    BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08
    TTC #1 since 1/10
    DX: Unexplained/??? MFI issues

    Our lil' lost sparks:
    5w3d loss 7/30/10 - EDD March 2011
    8w loss 4/15/11 - EDD November 2011
    8w3d loss 8/2/12 - EDD March 2013
    4w c/p loss 10/29/12 - EDD July 2013

    Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
    RPL testing all normal, Karyotyping normal

    Moving on to IVF.

    IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

    Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
    IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
    FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
    Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14

    After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14
    We are so in love with her.

    "I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

    Everybody is welcome!!!
  • PIO was the worst part for me! I am thin and those shots were torture. Not the shot themselves, but the days after, I couldn't even walk or sleep it hurt so bad. What helped was switching to 1inch needles but for me, I would take Crinone any day!

    Good luck! I hope you are tougher than I am :)

    IVF #3 = ID Twin Boys TTC #3, June 2011 FET #1 m/c 9 Weeks, October FET #2 BFN, December FET #3 BFN, March FET #4 c/p, June FET #5 BFN, July FET #6 embie didn't survive the thaw IVF#4 September 2012 Baby Birthday Ticker Ticker Identical twin boys born at 30 weeks 2 days due to HELLP
  • Definitely the emotional part. Also, I had miscarriages after both of my fresh cycles, so it made it all so much worse.

    DH: Severe MFI/Azoo Me: Compound heterozygous MTHFR
    IVF #1= m/c- methotrexate @6w2d
    FET #1= BFN
    IVF #2= m/c- D&C @8w5d
    IVF #3= Beta #1 9dp5dt= 252, Beta #2 11dp5dt= 417, Beta #3 17dp5dt= 4,952
    US #2 @ 7w2d= twins, baby B measuring behind
    US #3 @ 8w5d= Baby A doing well, no HR in baby B
    *S/PAIF always welcome* BabyFetus Ticker
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