TTC after 35

Anti-Mullerian Hormone (AMH) Experience?

I had blood taken to test my AMH this afternoon.  Any experience with this?  I just read up on it and I get what it tests but now I'm kind of freaked out.  If it's low is that a good indicator of crappy fertility?  I think I have to wait about a week for the results.Zip it!

Thanks!

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Re: Anti-Mullerian Hormone (AMH) Experience?

  • It took a week for me to get the results each time.  I've had it done 3 times (GYN and 2 different REs)- it was less than 0.16, 0.24 and 0.34 respectively.  Apparently anything under 1 is not good; but over 40 (like I am) they kind of expect it to be low.  They also look at FSH (mine is 11.2) and AFC. The NP at my GYN's office looked at my number and told me I'd never conceive without DE; the RE's I have seen think I have a shot with my OE. 

    One of the REs I spoke to told me it is an indicator typically of how well you'll respond to IVF- however; he has had women in his practice get PG with undectable AMH-  and carry the pregnancy to term.

    I think that the AMH is something that needs to be looked at within the context of the other tests, too.

    GL!

     

    image
    DOR and AMA
    2/12-5/12: 4 IUI cycles = all BFN;
    7/12: DE IVF # 1 (with ICSI)- 20R, 16M, 14F, 5DT of 2 blasts; 6 frosties = BFN;
    Lupus anticoagulant initially high, then found to be normal on hematology consult;
    Follow up testing in September all clear;
    Started synthroid for "high normal" TSH;
    FET # 1- late October 2012- BFP on FRER; beta # 1- 21(low), beta # 2- 48 (still low), beta # 3- 132, beta # 4- 1,293; beta # 5- 5,606; last beta- over 100,000. First u/s 11/21- heard heartbeat
    12/12- Officially an OB patient!
    Level 2 ultrasound at 20 weeks shows vasa previa and VCI
    Referral to MFM and mandatory c section for delivery
    Beautiful baby girl born at 34 weeks
    Finally home after 15 day NICU stay!
    Trying for sibling: FET # 2- May 2014; beta 5/31, BFN
    FET #3, early July 2014; beta 7/14, BFN
    DE IVF # 2- August 2014; 14R, 13M, 11F, 5dt of 2 blasts (3 AA), 5 frosties = BFN
    FET #4- December 2014, yet another BFN

    Dr. KK work up shows borderline uterine blood flow, elevated NK cells, and MTHFR mutation (homozygous for c677t)

    Added baby aspirin, prednisone, supplements, Metanx, and intralipids

    Switched to large clinic for final attempt; had endometrial receptivity testing in January; FET March 2015 = yet another BFN

    Likely OAD- NBC

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  • Mine came back very low .34 and RE said this indicated diminished ovarian reserve. :( very sad news for us. It was recommended that we go straight to IVF. Had to start with IUIs for insurance though. I hope you do not get same news, but if you do, I am here to commiserate and share experiences ( redundant I think) .

    I do agree with previous post about context of other tests and I have not given up hope!  

    Me 37 DH 40 TTC since 1/11 DOR AMH .34 DH S/A Great BFP 12/11! MC 1/12 IUI #1 2/12 BFN. IUI #2 3/12 BFN. IUI #3 4/12 BFN IVF #1 5/12 BFP! DD 2/13/12
  • Like the PP said, this is one of many tests that all tie together, and they like to see the level at 1 or higher.

    With mine being at 0.22 they told me it meant my ovaries are slowing down a bit and not working as well as they could be.  However, my diagnosis of Diminished Ovarian Reserve is the AMH level in conjunction with my high FSH level.

    The waiting is the hard part.  I hope you get good news from your test results!

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  • I'm pretty sure it's an indicator of number, but not quality of eggs. As we age, it should get lower so if your number is good, than great! you're younger than your age, but as long as it isn't super low, nothing will change about your RE's approach. At least that's what my RE said. She uses FSH and AFC to determine doses and manage expectations.

    I didn't get the test. My attitude. We were going to try one cycle of IVF no matter what, and what was it going to tell me, that I'm old? I already knew that. 

    Hopeully the test will indicate you're young for your age. 

  • I just had mine tested and it was .5.  I just started seeing an RE because we hadn't conceived and have been trying for 7 months.  My RE said that it wasn't impossible for me to get pregnant, but we shouldn't waste any time.  I have a 10 month old and we didn't have any problems conceiving him.  I'm wondering how fast does it decline? 
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  • My AMH level was very low.  Advisement was to see a fertility specialist as it would prove to be difficult to start a family.  This wasn't an option for my new husband and myself.  I changed doctors who decided to run other hormonal tests that were not as scary low as the AMH level.  He said not to worry about things and just check back in with him in a few months.  Lo and behold, one month after our marriage, I got a BFP at 40 years old.  I am now pregnant with #2 at 42 without really "trying", so for my case, that original AMH did not indicate my true ability to become pregnant. 
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  • I agree with previous posters that it really needs to be looked at in context with the rest of your day 3 bloodwork (FSH, TSH, Estradiol).

    Here's a good link to explain it all.

    https://www.fertilityplus.com/faq/hormonelevels.html 

    Single Mother by Choice. Life didn't work out the way I planned so I did it on my own. IUI #s 1-3, unmedicated = BFN, IUI #s 4-6, 50mg Clomid, Ovidrel = BFN IVF #1: 23R, 20M, 17F. 5 day transfer 2 blasts. 2 Snowbabies BFP 6dp5dt, Beta #1 7dp5dt = 58, Beta #2 9dp5dt = 114, Beta #3 10dp5dt = 187 1st Ultrasound = 5/3, not much to see yet. 2nd Ultrasound = 5/17, TWINS!!! Hospital Bed Rest at 32 weeks due to pre-ecclampsia and severe edema. Audrey Grace, 5lbs9oz, & Lydia Louise, 6lbs, born via emergency c-section on 12/6/12 at 36w1d My IVF Journey
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