Beta Doubling Question — The Bump
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Beta Doubling Question

If you have more than two betas should your third doubling time be counted from the first beta or the second beta?

The reason I ask is that I got my 3rd beta number yesterday and its making me really nervous.

08/18 #1 213

08/25 #2 1781

08/29 #3 2955

The first doubling time was 54.83, however my third calculated from the second is around 131 doubling time which is way out of the normal range. However if I calculate from beta 1 it is around 68 which is within the normal range.

My nurse said the number looked fine so I feel I should trust them and that they know what they are looking for. Its so hard not to overanalyze everything.

Thanks for the support here. I haven't been around much and I know I have been pretty selfish with my questions but I really appreciate the advice.

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Re: Beta Doubling Question

  • Doubling from one to the next in 2-3 days is a very rough guideline.  The rise will slow as you go on.  If you are in the range of normal (check betabase), I would not worry.  Soon an u/s will give you much more useful info.  GL!
    TTK 9/06 / TTC 10/08 / Twins 12/11 / Life Blog
    5 REs + 3 surgical hysteroscopies for septum/lap + 3 failed IUIs
    IVF w/ICSI/AH & acu = BFP!, unexplained spontaneous m/c @ 8w2d (our little girl),
    FET w/acu = BFP!, B/G twins!, lost MP @19w, dx w/funneling cervix @20w,
    twins nearly lost to IC @21w, saved by rescue cerclage, 17P & 16w of bedrest
    Our twins born @36w4d via CS when A came foot first

    Thankful for every day

    Baby Birthday Ticker Ticker

  • Betas slow down once they start getting high. This chart might help reassure you:

    "Normal" Doubling Time
    hCG levels Doubling Time
    Under 1200 mIU/ml 31-72 hours
    Between 1200 to 6000 mIU/ml 72-96 hours
    Over 6000 mIU/ml more than 96 hours

    ETA: Like the PP said, now that you are above the 2,000 mark, an u/s is much more reliable indicator of how things are going. GL!

    After TTC with IR PCOS:
    April 2011: Metformin 1500mg + Clomid 100mg + Ovidrel + Prometrium = BFP!
    Beta #1 at 14DPO: 197 Beta #2 at 18DPO: 1296
    At 40w6d, our Team Green surprise came by unplanned C-section and changed our lives forever!

    Lilypie First Birthday tickers
  • Loading the player...
  • Like pp said, betas slow as you get higher. I think you're fine! When is your u/s?
    Dx: High FSH, stage IV endo, homozygous C677T MTHFR and PAI-1
    Early loss 10/08
    Lap 1/09
    IVF #1 "natural IVF" - 1 egg retrieved, missed m/c
    Tried several mini-stim cycles with no response
    Switched clinics - dx'd as carrier for Fragile X
    IVF #2 MDL protocol Jan/Feb converted to IUI, BFN
    IVF #2 take 2: Antagonist, one embie, BFN
    IVF #3: Antagonist, no fertilization
    One last ditch effort at OE IVF (antagonist with Clomid) cancelled
    DE cycle #1 Jan/Feb 2011, BFP, ectopic
    DE cycle #2 June/July 2011 - BFP
    10/28/11 Baby girl lost at 17 weeks due to pre-term labor. We love and miss you.
    DE cycle #3 June/July 2012 - BFP, twins, both heartbeats stopped, D&C
    2 frosties but don't know what's next
    FET Dec 2012: BFP! Praying this one sticks for the long haul!
  • Thanks for the reassurance ladies. I hate that I can't just not let it bother me and go with the flow. I'm so not a go with the flow person!

     First US is a week from Thursday (9/8) I will be 7wks 1 day.

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    Lilypie First Birthday tickers

  • Just wanted to say congrats! Your betas look good to me.
    Two years, two rounds of IVF, AH, ICSI & Acupuncture brought us sweet baby G born 10/20/11


    [IMG]http://i44.tinypic.com/358v3mu.jpg[/IMG]
  • image cbubbles2:
    Just wanted to say congrats! Your betas look good to me.

    ditto! I know it is sooo hard to wait for an u/s -- I hope the next week goes by quickly for you :)

    TTC since 8/09
    DX: PCO, ENDO, High NK, MTHFR
    8/10 = Lap to remove Endo

    2 Femara TI, 3 Follistim IUI = BFN & 1 c/p
    IVF #1 - BFP - boy/girl Twins!

    Ben and Reese born at 34w2d!
  • Looks good to me... my RE doesn't even do a 3rd beta, we go straight to u/s. Good luck, keep us posted!!
    PAIFW/SAIFW
    TTC since 10/09 Dx: MFI

    IUI 1&2 (unmedicated)= BFN
    IUI 3 (100mg Clomid + Ovidrel) = BFP 2/14/11 missed m/c 3/18/11

    IUI 4 (100mg Clomid + Ovidrel) = BFP!!


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