Beta in--c/p

hollymichael · February 2011

Well, I was mostly right with my BFN. Beta came back at 5.45 at 13dp5dt. So, a very early chemical and they are having me stop all meds. At least the cramping wasn't in my head.

This is my second early c/p. First was two years ago on our second month TTC.

Dr. will be calling me later and I would like to be prepared with questions. Any thoughts? We did transfer poor embryos so I think that was probably the issue, but with two c/p, I want to make sure we aren't missing anything.

I have had RPL testing and two things came back borderline: protein S & APAs. In addition, I tested positive for MTHFR, but homocystine (sp?) levels were normal, so no blood thinners prescribed. I will ask if he thinks we should add lovenox next time.

I don't have much time to put together a list of questions before he calls. If you can think of anything I should ask, please share.

TIA!

jessican08 · February 2011

I wish I had some advice but I just wanted to say I'm so sorry. I hope you get some good answers on your call. ((HUGS))

June0609 · February 2011

I'm so sorry that you have another c/p. I hope your RE can figure out what the problem is so it won't happen again next time.

cbubbles2 · February 2011

I'm so sorry sweetie. I hope you get some answers today!

madelyn07 · February 2011

Oh no, I'm so sorry sweetie.

I really don't have any advice for you...after my c/p my RE just said it was likely "bad luck" but did agree to let me do a Thrombosis Profile..everything came back normal.

(((hugs)))

cookie_queen · February 2011

((hugs)) I don't have any advice for questions but I'm so sorry you are going through this.

vanessagorc · February 2011

I think all of ur questions sound good. I'm so so sorry. ((Huge hugs))

SLPMel · February 2011

I'm so sorry hun. I hope your RE is able to give you a good plan!!!

SLPMel · February 2011

I'm so sorry hun. I hope your RE is able to give you a good plan!!!

may2806 · February 2011

Hi Holly, I'm so sorry ((HUGS))

Are you on Folgard/additional folic acid for the MTHFR? I know they say if homocysteine is normal it's not a problem, but extra folic acid can never hurt. I also take baby aspirin which I think they're just letting me to do to humor me, but if you're not on it already you could ask about that. I don't know much else about protein S or APAs.

GL with the call. Let us know what the dr says.

magnolia_femme · February 2011

I'm so sorry about the c/p. I think your questions sound right on. ((hugs))

LadyGolfer523 · February 2011

I am so sorry. thinking of you ((HUGS)).

mikeandangie · February 2011

Gosh, I am so sorry, sweetie! I don't have much advice. I did ask about beta 3 integrin at my wtf, but RE dismissed it and my research showed a lot of RE's feel the same way. I think maybe ask about egg/sperm quality issues and if a different protocol can give you better embryos.

(((hugs)))

Ginger71 · February 2011

(((hugs))) Holly. I'm so sorry....

I was also borderline protein s deficient....I think it's worth a 2nd look....I had really different results each time the test was done. I am not sure if it is something that can fluctuate or not but I would make them repeat it.

My T + P are with you. I hope you can get some answers. More (((hugs)))

kthappy76 · February 2011

I don't have any advice, I just wanted to tell you how sorry I am. (((huge hugs)))

hollymichael · February 2011

may2806:

Hi Holly, I'm so sorry ((HUGS))

Are you on Folgard/additional folic acid for the MTHFR? I know they say if homocysteine is normal it's not a problem, but extra folic acid can never hurt. I also take baby aspirin which I think they're just letting me to do to humor me, but if you're not on it already you could ask about that. I don't know much else about protein S or APAs.

GL with the call. Let us know what the dr says.

Yes, I am on folgard and baby aspirin. Like you, I think they are just humoring me with the baby aspirin. Depending on what my RE says, I may call my hematologist (I see her for an unrelated condition) and get her thoughts too.

ginger67 · February 2011

Even though you may not need the lovenox it wouldnt hurt to be on it right? When did they test you? My hemo had me on a high dose the second I stared stims and progesterone, he said estrogen and progesterone make your blood thicker, maybe you were tested without these in your system?

What was your lining? Would Viagra, vitamin e help?

Were you on the Viivelle paches? If not can you be next time?

Im assuming your going to use a different donor?

Im so pissed off for you. I hope they throw every med possible your way and you find a kickass donor.

STL34 · February 2011

I'm so sorry. ((HUGS))

Did they do anything for your MTHFR? My BFF had several early losses with MTHFR being her only issue. Her homocysteine levels were normal so they treated her with high doses of folic acid and other B vitamins and baby aspirin. This worked for her.

With borderline APA and protein S, I would ask about trying a blood thinner. My new RE recently told me that heparin works better than lovenox in women with APAs.

I'm sorry you are going through this. I hope you have a productive call.

hollymichael · February 2011

Ginger71:

(((hugs))) Holly. I'm so sorry....

I was also borderline protein s deficient....I think it's worth a 2nd look....I had really different results each time the test was done. I am not sure if it is something that can fluctuate or not but I would make them repeat it.

My T + P are with you. I hope you can get some answers. More (((hugs)))

Mine was slightly low once and normal once. I think that is a good idea to see if I can have it tested again.

babystinkbreath · February 2011

holly I am so very very sorry. I was so hoping it would be better news. I don't have any additional advice for you on questions, but the pp have some good advice.

Edwina.McDunnough · February 2011

I'm so sorry. I really hate this for you.

If you haven't had a hysteroscopy, I'd do that, as well as retesting your CBCs to see that all is good and maybe SCSA to see if there any any concerns?

I hope you get some answers.

hollymichael · February 2011

STL34:

I'm so sorry. ((HUGS))

Did they do anything for your MTHFR? My BFF had several early losses with MTHFR being her only issue. Her homocysteine levels were normal so they treated her with high doses of folic acid and other B vitamins and baby aspirin. This worked for her.

With borderline APA and protein S, I would ask about trying a blood thinner. My new RE recently told me that heparin works better than lovenox in women with APAs.

I'm sorry you are going through this. I hope you have a productive call.

I am on folgard & baby aspirin for the MTHFR. This was my first time on folgard. Thanks for the info on lovenox v. heparin.

hollymichael · February 2011

ginger67:

Even though you may not need the lovenox it wouldnt hurt to be on it right? When did they test you? My hemo had me on a high dose the second I stared stims and progesterone, he said estrogen and progesterone make your blood thicker, maybe you were tested without these in your system? This is very interesting! I don't remember exactly when I was tested, but it wasn't when I was on meds.

What was your lining? Would Viagra, vitamin e help? At last check, my lining was 9.5 triple striped and that was several days before the transfer. The techs always compliment my lining, so I think that is the one thing I have going for me.

Were you on the Viivelle paches? If not can you be next time? I was on shots of del estrogen which does the same thing.

Im assuming your going to use a different donor? Absolutely!

Im so pissed off for you. I hope they throw every med possible your way and you find a kickass donor. Thanks! Me too!

BRSaugust20 · February 2011

I don't have anything to add but wanted to send you ((HUGS)). I am just devastated for you.

hollymichael · February 2011

Edwina.McDunnough:

I'm so sorry. I really hate this for you.

If you haven't had a hysteroscopy, I'd do that, as well as retesting your CBCs to see that all is good and maybe SCSA to see if there any any concerns?

I hope you get some answers.

CBCs done recently, but will ask about hysteroscopy and SCSA. Good idea.

Mrs.AmandaMqn · February 2011

I don't have any advice but wanted to say I'm sorry and give you ::hugs::

love2b_mrst · February 2011

I'm so sorry. Hope you can get some answers.

Nesting.Away · February 2011

I am so sorry, Hun. ((hugs))

theworms · February 2011

i'm so sorry cutie.

sounds like good questions. any additional sperm testing they can do?

patchen30 · February 2011

I'm so sorry ((hugs)). I think w/ a chemical most REs think that it's usually not blood clotting b/c those losses tend to happen later, and is usually chromosomal, but it can't hurt to cover bases. I know it seems like a donor should have "perfect" eggs and there shouldn't ever be a chromosomal issue, but considering that ~60% of even fertile's eggs are chromosomally abnormal, it is possible to just have "bad luck" even w/ a donor (think of all your fertile friends who've had m/c). I know that probably doesn't make you feel better though. I don't really have any advice on questions for him. I hope you feel better soon ((hugs))