2nd Trimester

Unisom?

Just called the OB's office. I haven't kept anything down in two days...not even water.  The nurse said to try unisom. She said it will make the nausea and vomiting go away.  If I'm still throwing up tomorrow I am supposed to go in and get IV fluids.

Anyone try unisom? What was your experience?

Re: Unisom?

  • A cocktail of Unisom + a B6 tablet before bed was the ONLY relief I found for my MS and HG. One of my OB's in the practice was a specialist at an HG clinic for a long time and she said that although they have no clue why this combo works, it seems to do the trick!
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  • I have been on it since 8 weeks, and it has been my lifesaver!  You only need half a tablet at bedtime (12.5 mg).  My dr. also said that another quarter tablet during the day is fine, but I only had to do that twice.  Now I'm finally feeling better, so I'm going to stop taking it.  But it worked great for me!! 

    Oh, and when my mom was pregnant, they recommended the same thing (this was 25 years ago!).  I also heard that taking vitamin B6 (25 mg) 4 times a day as well will help.  GL!

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  • B6 isn't working for me anymore so I'm hoping the unisom does. It's a sleep aid though, right? So if I take it during the day it'll knock me out?
  • I take Zofran and Unisom - it's the only combo that works.  I took it with both pregnancies.
  • It is a sleep aid, however if you only take a quarter of a tablet during the daytime, I found that I didn't get sleepy, just calm.  Kind of like taking a Pamprin for PMS.  Does that make sense?
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  • That's why I only took it at night. My doctor said to make sure to avoid the kind with diphenhydramine in it- it's only Benadryl and will only knock you out, it won't help the nausea. There is a kind that has doxylamine that is supposed to be the one you want. I took a whole tab at bedtime along with 25mg of the B6.
  • It knocks me out.  I take it at night.
  • It did not work for me. I had to get a Rx for Zofran.

    Unisom is sold as a sleep aid. It is an antihistamine, though. The same drug that's in Benadryl. I'm pretty sure 1 dose is 2 tablets, 50 mg. So I don't think a quarter of a tablet during the day would really knock you out, unless you're very sensitive to Benadryl.

    ETA: aha! I never found any with doxylamine in it. All they had at my pharmacy was the diphenhydramine kind.

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  • I haven't tried it, but my m/s was too bad to take anything that I had to swallow.  I threw up several different kinds of whole pills just after I swallowed them.  Even the zofran that dissolves on your tongue didn't work fast enough.  I watched several of them fall into the toilet less than half dissolved as I threw up.  I have the zofran pump.  It gives continuous meds subcutaneously.  It's the only thing that helps me.
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  • imagejustrachet:

    It did not work for me. I had to get a Rx for Zofran.

    Unisom is sold as a sleep aid. It is an antihistamine, though. The same drug that's in Benadryl. I'm pretty sure 1 dose is 2 tablets, 50 mg. So I don't think a quarter of a tablet during the day would really knock you out, unless you're very sensitive to Benadryl.

    ETA: aha! I never found any with doxylamine in it. All they had at my pharmacy was the diphenhydramine kind.

    I asked for Zofran and was told I didn't need it. I throw up 2-3 times a day most weeks. I'm so frustrated...especially since these past two days i have kept nothing down. I threw up FIFTEEN times yesterday. FIFTEEN! And the doctor thinks this is normal.

  • imagejustrachet:

    It did not work for me. I had to get a Rx for Zofran.

    Unisom is sold as a sleep aid. It is an antihistamine, though. The same drug that's in Benadryl. I'm pretty sure 1 dose is 2 tablets, 50 mg. So I don't think a quarter of a tablet during the day would really knock you out, unless you're very sensitive to Benadryl.

    This.  And I'm pretty sensitive to meds, since I don't take them ever, unless I have to.  And I was at the point where I was desperate, so thank goodness I tried it! 

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  • imageMrsRebecca:
    imagejustrachet:

    It did not work for me. I had to get a Rx for Zofran.

    Unisom is sold as a sleep aid. It is an antihistamine, though. The same drug that's in Benadryl. I'm pretty sure 1 dose is 2 tablets, 50 mg. So I don't think a quarter of a tablet during the day would really knock you out, unless you're very sensitive to Benadryl.

    ETA: aha! I never found any with doxylamine in it. All they had at my pharmacy was the diphenhydramine kind.

    I asked for Zofran and was told I didn't need it. I throw up 2-3 times a day most weeks. I'm so frustrated...especially since these past two days i have kept nothing down. I threw up FIFTEEN times yesterday. FIFTEEN! And the doctor thinks this is normal.

    Wow.  That doesn't seem right.  I've heard of women with less symptoms who get Zofran.  Aren't you dehydrated?  I'm sorry you're going through that...

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  • imageMrsRebecca:
    imagejustrachet:

    It did not work for me. I had to get a Rx for Zofran.

    Unisom is sold as a sleep aid. It is an antihistamine, though. The same drug that's in Benadryl. I'm pretty sure 1 dose is 2 tablets, 50 mg. So I don't think a quarter of a tablet during the day would really knock you out, unless you're very sensitive to Benadryl.

    ETA: aha! I never found any with doxylamine in it. All they had at my pharmacy was the diphenhydramine kind.

    I asked for Zofran and was told I didn't need it. I throw up 2-3 times a day most weeks. I'm so frustrated...especially since these past two days i have kept nothing down. I threw up FIFTEEN times yesterday. FIFTEEN! And the doctor thinks this is normal.

    Okay, I was worried about you when I thought you were throwing up a couple times/day.

    I would skip the OB and go right to the ER. Now. Vomiting 15 times/day is dangerous and you need to get some effective treatment ASAP. And register a complaint against the nurse who said throwing up 15 times in a day is "normal."

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  • imageMrsRebecca:

    I asked for Zofran and was told I didn't need it. I throw up 2-3 times a day most weeks. I'm so frustrated...especially since these past two days i have kept nothing down. I threw up FIFTEEN times yesterday. FIFTEEN! And the doctor thinks this is normal.

    Ugh. I guess some doctors are more stingy with Rxes than others. Sorry! I hope something works for you and/or the doctor sees the light.

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  • imagejenny1980:
    imageMrsRebecca:
    imagejustrachet:

    It did not work for me. I had to get a Rx for Zofran.

    Unisom is sold as a sleep aid. It is an antihistamine, though. The same drug that's in Benadryl. I'm pretty sure 1 dose is 2 tablets, 50 mg. So I don't think a quarter of a tablet during the day would really knock you out, unless you're very sensitive to Benadryl.

    ETA: aha! I never found any with doxylamine in it. All they had at my pharmacy was the diphenhydramine kind.

    I asked for Zofran and was told I didn't need it. I throw up 2-3 times a day most weeks. I'm so frustrated...especially since these past two days i have kept nothing down. I threw up FIFTEEN times yesterday. FIFTEEN! And the doctor thinks this is normal.

    Okay, I was worried about you when I thought you were throwing up a couple times/day.

    I would skip the OB and go right to the ER. Now. Vomiting 15 times/day is dangerous and you need to get some effective treatment ASAP. And register a complaint against the nurse who said throwing up 15 times in a day is "normal."


    This. seriously. I'm worried about you.

  • I was told to take the unisom and B6 too but for some reason the unisom just made me more awake.
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