TTC After a Loss

Clomid girls... might wanna pick up some NAC

1) Nutritional Supplement Helps You Ovulate

Researchers at Mansoura University in Egypt recently announced that "N-acetyl cysteine is proved effective in inducing or augmenting ovulation in polycystic ovary patients", according to their new study.

At the Vita-Salute University in Italy, researchers studied 25 PCOS women who were not having their cycle. At a dose of 4,000 milligrams a day, they were given a combination of inositol and folic acid (another B vitamin) for six months.

N-acetyl cysteine, known as NAC, is an amino acid that is available as a nutritional supplement (available at our online store). Amino acids are building blocks for proteins.

In this study, 470 PCOS women were given Clomid (clomiphene citrate) for one menstrual cycle and then given Clomid plus NAC for another cycle. The women took 1,200 mg of NAC for 5 days starting on day 3 of the menstrual cycle.

With Clomid alone, the ovulation rate was 17.9% but when the NAC was added, the ovulation rate was 52.1%. Progesterone levels and thickness of the uterine wall were reported to be also improved.

This study confirms an earlier study that the effectiveness of Clomid is increased when NAC is also taken. We refer to this earlier study on our NAC webpage. NAC is regarded as safe and has no side effects. It also appears useful for reducing insulin resistance, which is a big problem in polycystic ovarian syndrome.

NAC is a supplement to seriously consider.

Missed MC 1 - 11/21/2006 Missed MC 2 - 03/10/2008 BFP # 3 09/18/09 - Gabriel David born 05/11/2010 baby

Re: Clomid girls... might wanna pick up some NAC

  • I would change your title from Clomid users, to people with PCOS, as the effects are more for PCOS than just ovulation.  People taking clomid for reasons other than PCOS should not take this medication without talking to their docs first.

     "induced a hypoxia-like response in the expression of several important genes both in vitro and in vivo."

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  • Mmm  Very Tempting!   I have always been a little hesitant (sp?) to medicate myself, but this seems like a really good thing.  Maybe too good to be true.  I think I will google this later tonight and see what other information I can find.  I think I should probably take some healthy nutrional supplements.  I like that it seems to make other hormones balance out at the right levels too, like progesterone. 

     Thanks for the info and link.  I will definitely look into this!!

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