Trouble TTC

New MFI Research and baseline appt.

So my baseline went great this morning.  My AFC actually went up from January's; from 15 to 17 (8 on left, 9 on right) so I'm excited to get things started.  Especially since this is the first time in three years with some IF insurance coverage.  The admin laughed when I said it felt so weird to not have to fork over tons of cash on my way out the door.  

What was new, was the U/S tech gave me two new "talks" and said that my RE had wanted her to talk to me about due to some new studies.  The first was about BPA (a chemical that's in plastics and cans) in regards to MFI and morph specifically...now admittedly we don't have a huge issue with morph (number has been 7-9% on strict krueger) but wanted to pass it on.  They said simple changes made can improve sperm in as little as three days! (WHA?)  They say to avoid containers marked with #7 (polycarbonate containers), that those marked with #1, 2, 4 & 5 are generally safer for food and drinks.  She said avoid cans (like pop cans, soup cans etc) in the weeks leading up to treatment cycle, coffee cups from chains (ask them to put it straight into your porcelain, BPA free plastic bottle or stainless steel drinking container), do NOT microwave or store anything in plastics (except ziplock bags or clearly marked BPA free products).  Etc.  

The other new research that I found interesting is that studies showing a male ejaculating for a straight 7-10 days (every day) up to day of trigger have higher rates of pregnancy.  So, I called and passed on the new homework to DH that he needs to whack off or have sex with me every day starting today through next Tuesday (and I'll likely trigger on Tuesday).  I'll be interested to see how his post wash numbers are from this "experiment".  DH might get a bit exhausted, but honestly we won't be doing it much of that, probably just three times over the next week, and I can't think jerking off once a day takes as much out of you as sex  does.  But he laughed at his "homework" and was glad I called instead of sending him that email at work LOL.   


TTC since July 2009. Dx MFI & LPD. 
IUI#1&2&3 (2011 & 2012) BFN
IUI#4 1/23/13 on 75iu x9 Follistim = BFP then chem preg m/c (Feb 2013)
IUI#5 BFN (April 2013)
IVF w/ICSI Oct. 2, 2012 - 13R, 11M, 7F, 1 frozen blast 4BB grade - - - FET Nov 15, 2013
BFP! Beta 1:104 @ 10dp6dt, Beta 2:178 @ 12dp6dt,  beta 3:366 @ 14dp6dt
Saw heartbeat twice before missed M/C at 8w3d on 12/27/13, missing my little angel boy
JUNE 2014 IVF#2;  5R, 2M, 1F Three day transfer 6/7.  Beta 6/18 - BFN
Child Free Now?
S/PAIFW , S/PALW

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Re: New MFI Research and baseline appt.

  • Thanks for the info, very interesting!
    CafeMom Tickers
     Anniversary
    TTC since July 2011
    BFP #1: 2/15/12-Ectopic/Mtx at 6 wks

    BFP #2: 10/12/12-m/c at 5 wks. 
    BFP #3: 8/27/13
    Me: MTHFR, Low AMH (1.1), High NK cells and Antiphospholipid Antibodies.
    DH:MFI-Low morph (1%), DNA fragmentation: Excellent!
    5 rounds of clomid, 3 IUIs, and multiple non-medicated cycles- BFFN                                                      
    IVF with ICSI in August 2013 brought us our babies.  ER-9R, 7M, 4F w/ICSI  ET of 2-Grade 2 blasts. 
    + HPT at 6dp5dt. #1 (8dp5dt)- 105    #2 (13dp5dt)- 510  #3 (15dp5dt)- 960  #4 (17dp5dt)- 1889
    Dx shortened cervix, PTL, and preeclampsia during pregnancy.  Lots of medications and 13 weeks of bedrest, babies were born healthy at 34w4d!


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  • I was thinking about you this morning, and I'm so happy that things went well! Best of luck this cycle!
    Me: 37, DH: 35 :: TCC since 2/11 SA: Perfect! CD3  HSG = Blocked Right Tube
    April- Femara 2.5mg + Trigger + IUI = BFN   May- Femara 5mg = CX - No Response on Left = BFN
    June- Femara 7.5mg + Trigger + IUI = BFN  August- Lap & Hysteroscopy = Blocked & Partially Blocked Tubes
    September- Femara 5mg = CX - No Response on Left = BFN  October- 100mg Clomid + Trigger + TI = BFN
    IVF # 1: Stims 11/30 ER 12/12/12! (10R, 10M, 8F, 2T, 6 F) :: Beta #1- 176  c/p @ 4w4d
    FET #1 February 26th :: Lost 4 to Thaw, Transferred 2 = BFFN
    IVF # 2 Stims 5/10 ER 5/21 (15R, 13M, 13F, 2T, 7F- 6d3 & 1d5) :: Beta # 1- 15 c/p @ 4w
    FET #2 Cancelled, Right Tube Developed a Hydro  8/28 Hydro & Scar Tissue Removed  Cleared for FET
    FET #2.2 Scheduled for September 20th
    2 Thawed, 2 Transferred! Beta #1- 96, Beta #2 906! :: EDD June 10th
    2015- 2 failed FET. We are done
    SURPRISE! BFP 8/8/16   EDD 4/1/17

     
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  • Very interesting stuff! Thank you for sharing and glad your appointment went well! :)
    *** Trigger Warnings ***

    TTC #1 since March 2011
    Dx = Unexplained IF
    1 medicated TI cycle & 4 clomid IUIs = all BFNs
    June 2013 IVF #1 = 6 frosties + BFP!
    DS1 born 2/14

    TTC #2 since December 2014
    May 2015 unassisted BFP ended in m/c at 7wks
    April 2016 FET #1 = BFN
    June 2016 FET #2 = c/p
    August 2016 FET #3 = BFP!
    DS2 born 4/17
  • katib77katib77 member
    imageRumbera28:

    Thanks for sharing!  When I got my 'unexplained' diagnosis, I got a handout  that mentioned the horrors that BPA does to egg quality.  I stopped microwaving plastic, but I still store food in reusable Tupperware.  I think I'll stop.   I also didn't know that it was bad for sperm morphology though, but it makes sense!   

    I already avoid cans because I have a nickel allergy.  It took years for me to realize that cans were the source my eczema flareups (eczema and nickel sensitivity are related).   Good to know that it's good for my fertility too.

    The reason it can be bad for morph is because the chemical is synthetic estrogens, giving a man extra synthetic estrogen messes with the DNA of sperm.  She said of the women it affects, it makes them look more PCOS and can affect egg quality, but with my U/S she said "clearly, you don't seem to be affected by it."  ::::shrugs::::  IDK, it's just another thing to think about.


    TTC since July 2009. Dx MFI & LPD. 
    IUI#1&2&3 (2011 & 2012) BFN
    IUI#4 1/23/13 on 75iu x9 Follistim = BFP then chem preg m/c (Feb 2013)
    IUI#5 BFN (April 2013)
    IVF w/ICSI Oct. 2, 2012 - 13R, 11M, 7F, 1 frozen blast 4BB grade - - - FET Nov 15, 2013
    BFP! Beta 1:104 @ 10dp6dt, Beta 2:178 @ 12dp6dt,  beta 3:366 @ 14dp6dt
    Saw heartbeat twice before missed M/C at 8w3d on 12/27/13, missing my little angel boy
    JUNE 2014 IVF#2;  5R, 2M, 1F Three day transfer 6/7.  Beta 6/18 - BFN
    Child Free Now?
    S/PAIFW , S/PALW

    My Blog

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    Wow so interesting! I'm glad I caught this post today. Good luck Kati! I'll be thinking of you next week and lurking for a post regarding the IUI and post wash!

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    Married October 2009. Me 29 H 28.
    After 1 year of infertility, our little miracle was conceived via our 3rd IUI on May 5, 2013.
    Holland Sophia was born Jan 24, 2014.
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  • Thank you soooo much for the info. I'm going to look at every platic article we have and see what it is marked. I only buy BPA free water bottles and such, but we use plastic containers at home, and my DH likes bottled water. Also, we both drink out of can.. a lot.

    Sounds like a great appoitment! GL!! FX!!!!

    Me: 34 - Hydrosalpinx DH: 33
    Previous history
    IUI switched to TI x6 = BFN
    IUI x2 = BFN
    Essure procedure for hydro

    New starts

    *Possibly starting clomid in Sept or Oct 

  • RunCC37RunCC37 member
    Glad you had a good appointment! Thanks for the info!
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

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    My Blog: Running and Dreaming for Two ~ All are Welcome!
  • Thank for the info, very interesting. DH's first SA showed low morph, so this is very good information!
    TTC since 10/11
    Me, 26- Normal. DH, 28- Low morphology (2-4%)
    August 2013 100mg Clomid+TI=BFP!
    Beta #1,2,3=136, 1351, 5328
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  • Glad your appointment went well! Keeping my FX for you! 

    **************SIGGY WARNING**************

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    Me 32 :: DH 41

     TTC since November, 2011

    DH's SA : Excellent

    Lap and Hysteroscopy June 2012

    DX: PCOS, Stage III Endo, slight Adenomyosis, blocked tube, and probable LPD

    Treatments:  6 Months Lupron Depot injections; 1500 mg metformin; 3 cycles of Clomid + TI = BFN

    3 endometrial biopsies all were "out of phase" 

    September - December, 2013:  Break to lose weight and get healthy

    40 lb weight loss but still not ovulating "in phase"  

    February - March 2014: bcps + follistim + trigger + TI = BFP

     Beta #1 (12dpo): 30; Beta #2 (18dpo): 500; Beta #3 (25dpo): 7,000!!! 

    1st u/s 4/16: One beautiful hb at 144 bmp 

    2nd u/s 4/29: hb at 166 bmp.  Graduated from RE!!

    TEAM PINK! 

    Baby girl arrived on Thanksgiving day weighing 7lbs 6oz and measuring 20 inches

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  • rrdiva1rrdiva1 member
    That is great that you gained a few more follies! I have heard about unidentified, they make sense!
    Married BF 6/29/2002/
    TTC Since Aug 2011/
    ME:34 all clear/DH:41 DX Severe MFI/
    IVF w/ICSI OCT 2012 Stims started 10/8/ER 10/19/12/ET 10/24/Beta#1 11/2=BFN (beta was 1.2)

    IVF 2.0-Baseline 11/7/12 beta 0/All Clear
    Stim start 11/7/12//ER 11/19 11M//10F
    ET 2 embies 11/24//Beta#1 28 Beta #2 23 Beta#3 29
    stop meds Beta#4 37/C/P 5W5D EDD:8/12/13/IVF#3 in Jan

    Ivf 3-frozen 3 poor 3day/fet=bfn

    Ivf#4 New dr. New protocol=beta1 197 beta#2 677 beta#3 1557
     u/s 8/13 =TWINS 2 strong hb
    Due Date 4/4/14

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    My Chart//>
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