Speer! These are the greatest! I can't stop laughing!
Our TTC Journey
TTC #1: May 2011 BFP: 10/27/2011 | EDD: 6/30/12 DS born 6/28/12 via C/S
TTC #2: September 2018 Me: 36 | DH: 39 Mirena removed 9/13/2018 after 6 years BFP 11/11/2018 | MC @ 5.5 weeks on Thanksgiving July 2019 - Diagnosed with Secondary Unexplained IF August 2019 - 2.5 mg of Letrozole = Never Ovulated so Trigger and IUI were cancelled 9/30/2019 - IUI #1 (5 mg of Letrozole + Trigger) = BFP but Betas showed CP @ 4 weeks 10/28/2019 - IUI #2 (7.5mg of Letrozole + Trigger) = BFN 11/25/2019 - IUI #3 (7.5mg of Letrozole, Trigger + Crinone after IUI) = BFN 12/24/2019 - IUI #4 (7.5mg of Letrozole + Crinone after IUI) = BFN 1/24/2020 - IUI #5 (50mg of Clomid + Trigger + Crinone after IUI) = BFN and an Ovarian Cyst 3/2/2020 - Taking a break to reset/NTNP 11/1/2020 - At peace with where things are in life and are no long actively TTC. Whatever happens will happen and it will all be okay.
From Dr. SEARS:
Science tells us that when babies cry alone and unattended, they experience panic and anxiety. Their bodies and brains are flooded with adrenaline and cortisol stress hormones. Science has also found that when developing brain tissue is exposed to these hormones for prolonged periods these nerves wont form connections to other nerves and will degenerate. Is it therefore possible that infants who endure many nights or weeks of cryingitout alone are actually suffering harmful neurologic effects that may have permanent implications on the development of sections of their brain? Here is how science answers this alarming question:
Chemical and hormonal imbalances in the brain
Research has shown that infants who are routinely separated from parents in a stressful way have abnormally high levels of the stress hormone cortisol, as well as lower growth hormone levels. These imbalances inhibit the development of nerve tissue in the brain, suppress growth, and depress the immune system. 5, 9, 11, 16
Researchers at Yale University and Harvard Medical School found that intense stress early in life can alter the brains neurotransmitter systems and cause structural and functional changes in regions of the brain similar to those seen in adults with depression. 17
One study showed infants who experienced persistent crying episodes were 10 times more likely to have ADHD as a child, along with poor school performance and antisocial behavior. The researchers concluded these findings may be due to the lack of responsive attitude of the parents toward their babies. 14.
Dr. Bruce Perrys research at Baylor University may explain this finding. He found when chronic stress overstimulates an infants brain stem the part of the brain that controls adrenaline release, and the portions of the brain that thrive on physical and emotional input are neglected such as when a baby is repeatedly left to cry alone, the child will grow up with an overactive adrenaline system. Such a child will display increased aggression, impulsivity, and violence later in life because the brainstem floods the body with adrenaline and other stress hormones at inappropriate and frequent times. 6
Dr. Allan Schore of the UCLA School of Medicine has demonstrated that the stress hormone cortisol which floods the brain during intense crying and other stressful events actually destroys nerve connections in critical portions of an infants developing brain. In addition, when the portions of the brain responsible for attachment and emotional control are not stimulated during infancy as may occur when a baby is repeatedly neglected these sections of the brain will not develop. The result a violent, impulsive, emotionally unattached child. He concludes that the sensitivity and responsiveness of a parent stimulates and shapes the nerve connections in key sections of the brain responsible for attachment and emotional wellbeing. 7, 8
Decreased intellectual, emotional, and social development
Infant developmental specialist Dr. Michael Lewis presented research findings at an American Academy of Pediatrics meeting, concluding that the single most important influence of a childs intellectual development is the responsiveness of the mother to the cues of her baby.
Researchers have found babies whose cries are usually ignored will not develop healthy intellectual and social skills. 19
Dr. Rao and colleagues at the National Institutes of Health showed that infants with prolonged crying but not due to colic in the first 3 months of life had an average IQ 9 points lower at 5 years of age. They also showed poor fine motor development. 2
Researchers at Pennsylvania State and Arizona State Universities found that infants with excessive crying during the early months showed more difficulty controlling their emotions and became even fussier when parents tried to consol them at 10 months. 15
Other research has shown that these babies have a more annoying quality to their cry, are more clingy during the day, and take longer to become independent as children 1.
Harmful physiologic changes
Animal and human research has shown when separated from parents, infants and children show unstable temperatures, heart arrhythmias, and decreased REM sleep the stage of sleep that promotes brain development. 10 12, 13
Dr. Brazy at Duke University and LudingtonHoe and colleagues at Case Western University showed in 2 separate studies how prolonged crying in infants causes increased blood pressure in the brain, elevates stress hormones, obstructs blood from draining out of the brain, and decreases oxygenation to the brain. They concluded that caregivers should answer cries swiftly, consistently, and comprehensively. 3 and 4
P. Heron, NonReactive Cosleeping and Child Behavior: Getting a Good Nights Sleep All Night, Every Night, Masters thesis, Department of Psychology, University of Bristol, 1994.
M R Rao, et al; Long Term Cognitive Development in Children with Prolonged Crying, National Institutes of Health, Archives of Disease in Childhood 2004; 89:989992.
J pediatrics 1988 Brazy, J E. Mar 112 3: 45761. Duke University
LudingtonHoe SM, Case Western U, Neonatal Network 2002 Mar; 212: 2936
Butler, S R, et al. Maternal Behavior as a Regulator of Polyamine Biosynthesis in Brain and Heart of Developing Rat Pups. Science 1978, 199:445447.
Perry, B. 1997, Incubated in Terror: Neurodevelopmental Factors in the Cycle of Violence, Children in a Violent Society, Guilford Press, New York.
Schore, A.N. 1996, The ExperienceDependent Maturation of a Regulatory System in the Orbital Prefrontal Cortex and the Origen of Developmental Psychopathology, Development and Psychopathology 8: 59 87.
KarrMorse, R, Wiley, M. Interview With Dr. Allan Schore, Ghosts From the Nursery, 1997, pg 200.
Kuhn, C M, et al. Selective Depression of Serum Growth Hormone During Maternal Deprivation in Rat Pups. Science 1978, 201:10351036.
Hollenbeck, A R, et al. Children with Serious Illness: Behavioral Correlates of Separation and Solution. Child Psychiatry and Human Development 1980, 11:311.
Coe, C L, et al. Endocrine and Immune Responses to Separation and Maternal Loss in NonHuman Primates. The Psychology of Attachment and Separation, ed. M Reite and T Fields, 1985. Pg. 163199. New York: Academic Press.
Rosenblum and Moltz, The MotherInfant Interaction as a Regulator of Infant Physiology and Behavior. In Symbiosis in ParentOffspring Interactions, New York: Plenum, 1983.
Hofer, M and H. Shair, Control of SleepWake States in the Infant Rat by Features of the MotherInfant Relationship. Developmental Psychobiology, 1982, 15:229243.
Wolke, D, et al, Persistent Infant Crying and Hyperactivity Problems in Middle Childhood, Pediatrics, 2002; 109:10541060.
Stifter and Spinrad, The Effect of Excessive Crying on the Development of Emotion Regulation, Infancy, 2002; 32, 133152.
Ahnert L, et al, Transition to Child Care: Associations with Infantmother Attachment, Infant Negative Emotion, and Cortisol Elevations, Child Development, 2004, MayJune; 753:649650.
Kaufman J, Charney D. Effects of Early Stress on Brain Structure and Function: Implications for Understanding the Relationship Between Child Maltreatment and Depression, Developmental Psychopathology, 2001 Summer; 133:451471.
Teicher MH et al, The Neurobiological Consequences of Early Stress and Childhood Maltreatment, Neuroscience Biobehavior Review 2003, JanMar; 2712:3344.
Leiberman, A. F., Zeanah, H., Disorders of Attachment in Infancy, Infant Psychiatry 1995
Our TTC Journey
TTC #1: May 2011 BFP: 10/27/2011 | EDD: 6/30/12 DS born 6/28/12 via C/S
TTC #2: September 2018 Me: 36 | DH: 39 Mirena removed 9/13/2018 after 6 years BFP 11/11/2018 | MC @ 5.5 weeks on Thanksgiving July 2019 - Diagnosed with Secondary Unexplained IF August 2019 - 2.5 mg of Letrozole = Never Ovulated so Trigger and IUI were cancelled 9/30/2019 - IUI #1 (5 mg of Letrozole + Trigger) = BFP but Betas showed CP @ 4 weeks 10/28/2019 - IUI #2 (7.5mg of Letrozole + Trigger) = BFN 11/25/2019 - IUI #3 (7.5mg of Letrozole, Trigger + Crinone after IUI) = BFN 12/24/2019 - IUI #4 (7.5mg of Letrozole + Crinone after IUI) = BFN 1/24/2020 - IUI #5 (50mg of Clomid + Trigger + Crinone after IUI) = BFN and an Ovarian Cyst 3/2/2020 - Taking a break to reset/NTNP 11/1/2020 - At peace with where things are in life and are no long actively TTC. Whatever happens will happen and it will all be okay.
Re: Ugh.....CIO
BFP: 10/27/2011 | EDD: 6/30/12
DS born 6/28/12 via C/S
TTC #2: September 2018
Me: 36 | DH: 39
Mirena removed 9/13/2018 after 6 years
BFP 11/11/2018 | MC @ 5.5 weeks on Thanksgiving
July 2019 - Diagnosed with Secondary Unexplained IF
August 2019 - 2.5 mg of Letrozole = Never Ovulated so Trigger and IUI were cancelled
9/30/2019 - IUI #1 (5 mg of Letrozole + Trigger) = BFP but Betas showed CP @ 4 weeks
10/28/2019 - IUI #2 (7.5mg of Letrozole + Trigger) = BFN
11/25/2019 - IUI #3 (7.5mg of Letrozole, Trigger + Crinone after IUI) = BFN
12/24/2019 - IUI #4 (7.5mg of Letrozole + Crinone after IUI) = BFN
1/24/2020 - IUI #5 (50mg of Clomid + Trigger + Crinone after IUI) = BFN and an Ovarian Cyst
3/2/2020 - Taking a break to reset/NTNP
11/1/2020 - At peace with where things are in life and are no long actively TTC. Whatever happens will happen and it will all be okay.
BFP: 10/27/2011 | EDD: 6/30/12
DS born 6/28/12 via C/S
TTC #2: September 2018
Me: 36 | DH: 39
Mirena removed 9/13/2018 after 6 years
BFP 11/11/2018 | MC @ 5.5 weeks on Thanksgiving
July 2019 - Diagnosed with Secondary Unexplained IF
August 2019 - 2.5 mg of Letrozole = Never Ovulated so Trigger and IUI were cancelled
9/30/2019 - IUI #1 (5 mg of Letrozole + Trigger) = BFP but Betas showed CP @ 4 weeks
10/28/2019 - IUI #2 (7.5mg of Letrozole + Trigger) = BFN
11/25/2019 - IUI #3 (7.5mg of Letrozole, Trigger + Crinone after IUI) = BFN
12/24/2019 - IUI #4 (7.5mg of Letrozole + Crinone after IUI) = BFN
1/24/2020 - IUI #5 (50mg of Clomid + Trigger + Crinone after IUI) = BFN and an Ovarian Cyst
3/2/2020 - Taking a break to reset/NTNP
11/1/2020 - At peace with where things are in life and are no long actively TTC. Whatever happens will happen and it will all be okay.