Infertility Veterans

Some advice for an IF member?

Hi All,

I've been on the IF board since Aug 2012 from my first IVF and have now just received my second BFN for IVF#2 (we did 3 IVFs in total but one was cancelled due to low E2).

I'm having a WTF appointment (first one with Cornell) on Friday with my RE and I'm hoping to come prepared with some questions and really press next steps.  From what I've read Cornell isn't all that into immune testing but I've been reading up on it and am interested.  Especially MTHFR as my mother had a pregnancy where the baby had severe spina bifida...I am on high dose extra folic acid but I know this can be processed differently than other formulations.

Between reading the posts here and my own research, here are some additional tests/procedures I would like to bring up to my RE.  Could you please let me know of anything else I may be missing or important questions you would suggest I ask from your own experience?  I truly value everyone's experience here and between IFV and IF, have learned so much.

  • Anti-phospholipid Antibodies -
  • Anti-Nuclear Antibodies -
  • Anti-Thyroid Antibodies
  • Activated Protein C Resistance
  • Protein C Activity
  • Protein S Activity
  • Prothrombin 20210 Mutation
  • MTHFR
  • Fasting plasma Homocysteine level (cardic)
  • Factor V Leiden (DNA)
  • Anti-thrombin III activity
  • Lupus Anticoagulant
  • Plaminogen Activator Inhibitor-1 (activity)
  • Anti-Cardiolipin IgG, IgM, IgA
  • Beta-2 Glycoprotein IgG, IgM
  • Phosphatidylserine IgG, IgM 
  • Natural Killer (Nk) Full Panel 

 

  • Thyroid panel (TSH) -
  • Karyotyping of Parents -
  • Celiac
  • Vit D

Additional Procedures:

  • Laparoscopy -
  • Endometrial Biopsy (EMB)
  • DFI Fragmentation

Apologies for the lengthy post and that my stupid siggy won't update.  Have a cupcake.

  image 

Anniversary Unexplained IF || TTC #1 since July 2011 || IUI#1 = BFN || IUI#2 = BFN || IUI#3 = Cx, overstimulated || IUI#3.1 = Converted to IVF || IVF#1 = BFN || IVF#2 = Cancelled due to low E2 || Changed RE, IVF#2.1 March 2013

Re: Some advice for an IF member?

  • That's a really good list - and you should definitely bring it up. 

    I didn't cycle at Cornell - but I did do a phone consult with them after our 4 failed IVFs.  And out of the four REs we talked to at that point - I found them to be by

     TTC #1 since 6/09
    Dx: PCOS and MFI
    3 IUIs, 4 IVFs = BFFN
      3rd RE: IVF #5/FET = BFP
    14dp5dt=1170 16dp5dt=2573

    1st u/s=
    TWINS!
    It's a Boy and a Girl!

    Born at 34w3d! 
     

  • Loading the player...
  • imagehootie123:

    That's a really good list - and you should definitely bring it up. 

    I didn't cycle at Cornell - bu

    Anniversary Unexplained IF || TTC #1 since July 2011 || IUI#1 = BFN || IUI#2 = BFN || IUI#3 = Cx, overstimulated || IUI#3.1 = Converted to IVF || IVF#1 = BFN || IVF#2 = Cancelled due to low E2 || Changed RE, IVF#2.1 March 2013
  • Ticker warning

    I am sorry for your failures. I would not talk to your re about immune testing because its like a foreign concept to them I would consult with an RI. So you have any immune diseases? Also do not go to SIRM it is a huge waste of
    6 m/c
    Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
    Natural cycle Dec 2010 BFP M/C 6 1/2 Weeks, D&E Jan 2011
    1 Clomid/Ovidrel BFN May 2011
    Natural cycle Aug 2011 BFP M/C 4 Weeks
    1 IUI Sept 2011 BFP M/c 7 weeks
    Provera Dec 2011 BFP M/C 3 Weeks
    DQ ALPHA HLA MATCH, High NK Cells Diagnosed Dec 2011
    IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
    IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
    Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
    Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone) 
    Went to Beer Center- high tnf, low lad, implantation failure
    Nov/Dec 2012 LIT Treatment
    Dec 12 Humira
    Jan 2013 BFP
    Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
    Miracle Born August 2013 Premature

    Yours doesn't have to be a sad story



    image
    image


    Lilypie - (ugiy)


  • imageluvboston:
    Ticker warning I am sorry for your failures. I would not talk to your re about immune testing because its like a fo
    Anniversary Unexplained IF || TTC #1 since July 2011 || IUI#1 = BFN || IUI#2 = BFN || IUI#3 = Cx, overstimulated || IUI#3.1 = Converted to IVF || IVF#1 = BFN || IVF#2 = Cancelled due to low E2 || Changed RE, IVF#2.1 March 2013
  • Didn't Dr. Beer pass away? OP,  I saw Dr Kwak-kim & loved her!!  My RE doesn't believe in immunology really, so I went on my own.  Feel free to PM me if you have questions.
    "Everything will be alright in the end. So if it's not alright, it is not yet the end."
    Me:29 DH:29  TTC since 1/11 Dx: unexplained IF/early DOR/immune issues 
    Feb'12- July'12-testing(all clear minus slight arcuate ute), 3 IUI with clomid all BFN
    8/30IVF#1 Antagonist protocol- ER 9/11-8R, 7M, 5F. 
    ET 9/14 2 embies transferred. 1 10cell Grade 4, 1 8cell Grade 4. No frosties. BFN
    IVF#2 Antagonist protocol plus baby aspirin- ER 12/5-16R, 12M, 8F!
    ET 12/10 5dt! 1 fully expanded blast & 1 early blast. No frosties. BFN
    3/13 hysteroscopy & polypectomy, Consulted w Dr. Kwak-Kim.  
    DX: High NK cells, cytokines, DHEAs& PAI1;  hypothyroid, +APA, restricted bloodflow
    7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle
    (plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim)
    ER 7/19 14R, 11M, 9F(4 natural fert, 5 with ICSI)
    ET 5dt 7/24 2 fully expanded blasts.  SURPRISE 3 FROSTIES!!!
    Beta #1 8/2 335!!!! Beta #2 829!!!  1st u/s 8/14 showed TWINS!!!!!
    11/11: TEAM PURPLE!!!!!
    3/21/14-L&W born at 37w via csection

    Here Comes the Sun Blog
    PAIF/SAIF welcome!
  • imageMrsRedVelvet:
    imagehootie12
     TTC #1 since 6/09
    Dx: PCOS and MFI
    3 IUIs, 4 IVFs = BFFN
      3rd RE: IVF #5/FET = BFP
    14dp5dt=1170 16dp5dt=2573

    1st u/s=
    TWINS!
    It's a Boy and a Girl!

    Born at 34w3d! 
     

  • imagemegs3084:
    Didn't Dr. Beer pass away?nbsp;OP, nbsp;I saw Dr Kwakkim amp; loved her!!nbsp; My RE doesn't believe in immunology really
    6 m/c
    Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
    Natural cycle Dec 2010 BFP M/C 6 1/2 Weeks, D&E Jan 2011
    1 Clomid/Ovidrel BFN May 2011
    Natural cycle Aug 2011 BFP M/C 4 Weeks
    1 IUI Sept 2011 BFP M/c 7 weeks
    Provera Dec 2011 BFP M/C 3 Weeks
    DQ ALPHA HLA MATCH, High NK Cells Diagnosed Dec 2011
    IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
    IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
    Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
    Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone) 
    Went to Beer Center- high tnf, low lad, implantation failure
    Nov/Dec 2012 LIT Treatment
    Dec 12 Humira
    Jan 2013 BFP
    Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
    Miracle Born August 2013 Premature

    Yours doesn't have to be a sad story



    image
    image


    Lilypie - (ugiy)


  • Gotcha, I read his book and I think he also trained Dr kwak. She took over for him when he left RFU to open his center.
    "Everything will be alright in the end. So if it's not alright, it is not yet the end."
    Me:29 DH:29  TTC since 1/11 Dx: unexplained IF/early DOR/immune issues 
    Feb'12- July'12-testing(all clear minus slight arcuate ute), 3 IUI with clomid all BFN
    8/30IVF#1 Antagonist protocol- ER 9/11-8R, 7M, 5F. 
    ET 9/14 2 embies transferred. 1 10cell Grade 4, 1 8cell Grade 4. No frosties. BFN
    IVF#2 Antagonist protocol plus baby aspirin- ER 12/5-16R, 12M, 8F!
    ET 12/10 5dt! 1 fully expanded blast & 1 early blast. No frosties. BFN
    3/13 hysteroscopy & polypectomy, Consulted w Dr. Kwak-Kim.  
    DX: High NK cells, cytokines, DHEAs& PAI1;  hypothyroid, +APA, restricted bloodflow
    7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle
    (plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim)
    ER 7/19 14R, 11M, 9F(4 natural fert, 5 with ICSI)
    ET 5dt 7/24 2 fully expanded blasts.  SURPRISE 3 FROSTIES!!!
    Beta #1 8/2 335!!!! Beta #2 829!!!  1st u/s 8/14 showed TWINS!!!!!
    11/11: TEAM PURPLE!!!!!
    3/21/14-L&W born at 37w via csection

    Here Comes the Sun Blog
    PAIF/SAIF welcome!
This discussion has been closed.
Choose Another Board
Search Boards
"
"