Hi. Thought I would join the board again after a long break. We did IVF #1 in June last year and it ended in a miscarriage/D&C in August. It was obviously pretty devastating for us and I needed to stop visiting the boards for my mental health. Since that cycle failed, we went ahead and had my DH go through the varicocele surgery in October. We didn't really expect a big change, but thought we might as well try; unfortunately, the surgery had no effect on improving his counts. We recently changed clinics/doctors and I was diagnosed with DOR (I'm 29 and have never had indications of problems before, so that was surprising). I had my baseline ultrasound and blood work today, start BC tonight, and will start stimming in mid-April. I'm glad to be back. Hope I can provide a little help for those that have questions since I've been through this once before, and I'm looking forward to being part of the community again.
Married: December 2005 ~ Started TTC: December 2008 ~ DH: 33, Me: 30
Diagnosis: severe MFI, late ovulation, short LP, DOR
Only option is IVF/ICIS. Waited several years before treatment because we're OOP.
IVF/ICIS #1 in June 2012 (Protocol: Long Lupron). Stims: 6/17/12, ER: 6/30/12 (6R, 5M, 4F), ET: 7/5/12 (1 4AA embryo transferred, 0 made it to freeze) ~ Beta#1: 7/14/12 - 55, Beta#2: 7/16/12 - 100, Beta#3: 7/18/12 - 199 ~ Limbo for weeks, finally confirmed pregnancy not viable: 8/13/12 ~ D&C: 8/17/12
Varicocele Surgery: October 2012 (long break to wait for results, no change)
Changed clinics: February 2013
IVF/ICIS Attempt #2 in April 2013 (Protocol: Antagonist). Stims: 4/12/13, Cycle Cancelled: 4/17/13 for poor follicle response and low E2 rise.
IVF/ICIS Attempt #3 in May 2013 (Protocol: LEAP) Cycle Cancelled: 5/20/13 at suppression check due to cyst
IVF/ICIS Attempt #4 in July 2013 (Protocol: LEAP). Stims: 7/20/13, ER: 8/1/13 (12R, 11M, 9F), ET: 8/6/13 (3 fair embryos transferred, 0 made it to freeze) ~ Beta#1: 8/15/13 - 86, Beta#2: 8/18/13 - 390.6, Ultrasound: 9/3/13 - TWO HEARTBEATS!
Re: Re-intro (waves hi)
IVF #1: ER 1/23/13- 4 eggs retrieved, 3 eggs fertilized; ET with 1 embryo 1/28/13 2 frosties beta #1 2/5 was 4.8- beta #2 2/7 3.5; BFN
FET #1- transferred one beautiful 4AA embie. Praying this is my take home baby. Beta 5/7/13- BFFN!!!
IVF #2: ER 7/17/13: 6R/3F- transferred 1 blast and 1 10 cell embryo 5dt. Beta hell. #1 2.5, #2 2.2- BFFFN! REALLY?
IVF #3: ER 12/1 and only 2 retrieved. 1 fertilized with ICSI. Was planning on transferring one fresh and one frozen....fresh was only 14 cells at day 5...CANCELLED and devastated due to 5cm blood filled cyst in ovary and blood in uterus.
IVF #4: Antagonist protocol with endometrial scratch day one of stims. ER 4/21: 6R/4M/3F- transferred 2 beautiful blasts (5dt) and one was hatching! No frosties but hoping we won't need it! Beta 5/4/14- 444(8dp5dt), Beta #2 10dp5dt 1002! THIS HAS GOT TO BE IT!!!!!!!!!! First US 5/15 we saw two of the most beautiful gestational and yolk sacs I have ever seen!
****FINALLY PREGNANT WITH DI/DI TWINS!!!!!!!
Sorry for the edit...apparently I cannot type.
(waves hi back)
sorry for your loss. glad you're back
1st cycle of IVF w/ ICSI = started bcp's 8/2/12, lupron 8/22/12, stims 9/7/12,ER 9.20.12 ET 9/23/12 3dt 1 6A and 1 4B; Positive HPT 10/2/12, BFP Beta 10/3/12: 38!, 2nd Beta 10/5/12 28
IVF #2 w/ ICSI = bcp 3/1, ER/ET planned for the week of 4/8
TTC SINCE 7/2010, BFP-10/2010 ended in miscarriage 11/2010 : (.....
Progesterone level 4/2011= 11.29. SA normal. HSG normal.
8/11 Clomid 50mg=BFN progesterone level 35,
10/11 Clomid 50mg =BFN progesterone level 31,
11/11 Clomid 50mg=BFN progesterone level 12,
12/11 Clomid 50mg=Progesterone 31
01/12-Break from meds-BFN
Feb-cd3 blood work FSH(5), AMH(0.56) 02/12 Break....
03/01/12-Clomid 50mg with IUI #1=BFN.
04/01/12-Another round of clomid with IUI#2=BFN.
5/8/12-Diagnostic Laparoscopy-found minimal endometriosis and small fibriod.
June and July-much needed break
August-Bravelle 75 with IUI#3- BFN
September-Bravelle injects with IUI #4-BFP!! MC 10/7/12 : ( Sonohysterogram-Normal
December- Bravelle(3 good follicles & E2 1252) with IUI#5 BFFN
July IVF #1- BFP! : ) Beta #1-245, #2- 703, #3- 1655, #4- 3553 YAY! Praying and Praying this one sticks around!
1st U/S scheduled for Aug 23rd!
Twins!!
We are having a BOY & a GIRL !!
My BLOG: www.ivfbabyquest.wordpress.com -Update - old blog.
PAIF/SAIF Welcome!
Me: 42, Hubby: 35, TTC since Jan 2010. Dx: DOR due to advanced maternal age. Also: Hypothyroidism (100mcg Levothyroxin). Positive for MTHFR (hetero-C677T), Factor V Leiden, and Fragile X (on DH side). Taking pre-natal vitamins.
First natural PG 9/27/11; mc: 1/20/12
First RE visit: 8/8/12, Saline Sonogram: 8/28/12, IVF injection class: 10/11/12, add FaBB Tab for FVL, +Vitamin D.
IVF #1: 10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Prog- 0.3 The u/s showed 6 follicles in my right & 9 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 10/21/12: Add Ganirelix SQ every morning.
ER 10/28/12: 13 Retreived. 7 Mature. 6 Fertilized. 5 Made it to PGS. ET 11/2/12: CANCELED. All 5 came back from PGS as having "severe abnormalities."
IVF #2: 1/7/13 Baseline: FSH- 8.8, 4 follicles in my right & 6 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 1/11/13: Add Ganirelix SQ every morning. hCG Trigger 1/16/13
ER 1/18/13: 9 Retrieved. 5 Mature. 5 Fertilized. 2 Made it to PGS. ET 1/23/13: CANCELED. All embryos (he even sent the ones not growing) came back from PGS as having "multiple severe abnormalities."
IVF #3: NEW RE! 3/1/13 Baseline: FSH- 9.6, E2- 61, Prog- 0.94, 3 follicles in my right & 4 in my left. Rx: 150 Bravelle& 150 Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ.
ER 3/11/13: 6R, 2M, 2F. Day 3: one 8 cell, grade 0. Five day ET 3/16/13: one early blast, grade Fair. 3/24/13 AF came a day before beta. BFN
IVF #4: (Added acupuncture to this cycle.) 3/25/13 WTF & Baseline: FSH-11.8, E2- 56, Prog- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5 follicles in my right & 4 in my left. Rx: 225 Bravelle& 225 Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM.hCG Trigger 4/3/13 SQ.
ER 4/5/13: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2 (Scale 0-best to 3-worst). Five day ET 4/10/13: two blastocysts (the 3rd stopped growing.) Beta 4/18/13: 2.5 BFFN. RE recommends we stop trying and focus on living childless, due to the extremely poor quality of my eggs.
***Decided to stop trying and live CFNBC. I couldn't adjust. So, six months later...
IVF #5: Changed RE. Going to one of the big name clinics now. OWDU: 10/29/13. Update: HORRIBLE experience. Disgusted and distraught at their complete unprofessionalism and how much money and precious time they cost us. Sickening. Have now changed RE again. New Patient appt. 1/30/14.
BFP! Out of nowhere, I got KU the old fashioned way! POAS 1/26/14 - Positive! FDLM 12/30/13. Beta #1 16dpo= 373. Beta #2 18dpo= 801. EDD 10/6/14
2/4/14 1st U/S revealed a 5wk2day sac but no fetal pole. Started 200mgs of progesterone suppositories daily
2/11/14 2nd U/S revealed a perfect 6wk1day "diamond ring" embryo with a beating heart! 138bpm! Add 1mg folic acid and 40mg Lovenox
2/25/14 3rd U/S: perfect 8w1d embryo, 178bpm. 3/6 start spotting. 3/11 10w1d U/S shows no heartbeat. Scheduling D&C. The Stork has forsaken me again.
IVF #5.2: New in-state RE. Supplement priming for 1.5 cycles prior to start of cycle, including DHEA 50mg (stopped 5/15), CoQ10 200mg 2x/day, L-Arginine- 1000mg 2x/day (stopped 6/5 due to cold sore!), myo-inositol- 2g 2x/day, melatonin- 3mg, and Neevo (prenatal for MTHFR).
5/16/14 Day 2 bw cycle prior: FSH- 12.22, E2- 38.37, Prog- 1.35, LH- 9.46. 6/2/14 Day 19 bw: Prog- 23
6/12/14 Baseline: E2- 122.7, Prog- 0.4. 5 follicles in left, 4 follicles in right. Start stims: 375IU Follistim & 150IU Menopur. 6/19 Increase Follistim to 425IU, Menopur still 150IU. 6/18 add Ganirelix. 6/23 Ovidrel trigger SQ. 6/25 ER: 8R, 8M, 5F naturally. Start Medrol & Doxy. 6/26 Start Endometrin. 7/2 Start Lovenox.
7/8/14 Beta= 137.4 BFP!!! (My first from IVF!) E2- 1109, Prog- >60. Stop CoQ10, myo-inositol, and melatonin. 7/9 2nd Beta= 281.4. TSH- 2.70. Increasing Synthroid to 100mcg daily. 7/24 6w3d u/s measured 6w3d, hb: 121bmp! 8/5 8w1d u/s measured 8w3d, hb: 164bpm! Graduated from RE to OB. Now I just need to find an OB!
EDD 3/18/15!
| Married since 2008 | DH and I: Both 30 | Me: Endometriosis and Carrier of an X-Linked Dominant Genetic Disorder | DH: Low Morph | Planning IVF with PGD and PGS in 2013 | Freeze-All IVF #1: March 2013 ER 3/26. 29R, 12M, 11F. 4 5AA frozen blasts. Freeze-All IVF#2: May 2013 ER 5/15. 31R, 21M, 20F. 6 5AA frozen blasts. Our PGD probe was completed in late June (total of 20 weeks to develop). PGD and PGS Results came on 6/19: 3 healthy embryos (normal chromosomes and unaffected by my family's genetic disorder). FET #1: July 2013 Natural Cycle - Cancelled due to insufficient lining (only got to 7.5mm). FET #1.2: August 2013 - Medicated Cycle with Lupron & Estrogen Patches to build up lining. Single embryo transfer was 8/23. Beta #1: 240! Beta #2: 578! U/S on 9/19 at 6w4d: We saw the heart beating at 131bpm. Second U/S on 10/4 at 8w5d: We saw the heart beating at 178bpm. EDD 5/11/2014
DX: DH (30) severe MFI, severely low count & low motility
Me (32): all clear
Appt with Urologist 5/21/12: exam, ultrasound, bloodwork all normal.
Testicular Biopsy with TESE on 6/8/12. good sperm found! (left side only) froze sperm, failed thaw test
Orientation for IVF/ICSI on 6/13/12. Waiting for the green light following biopsy results...results show adequate sperm production both sides.
2nd SA 6/18/12: sample is "adequate for ICSI"
Plan: IVF/ICSI July 2012!
ER: 7/26/12. 15 eggs retrieved, all mature.
TESE/TESA/aspiration from epididymis, no motile sperm found
froze all eggs, the saga of praying for good sperm continues.
8/3/12: 2nd opinion from MFI uro on biopsy slides. Suspects "partial late maturation arrest."
Plan: more SAs, third biopsy/TESE with frozen back-up either from DH or DS.
SA 8/17/12: Zero sperm
SA 8/23/12: Zero sperm
9/26/12: SPERM FOUND! 15 eggs thawed, 12 survived and were ICSI'd, only 3 fertilized normally. Refrozen as embies and will thaw in Nov. Please survive and grow!
All 3 survived the thaw on 11/15/12!
FET 11/17/12: transferred 2, one 4B, one 4C. Beta 11/30:BFFN
moving on to DS
DIUI#1 2/18/13,50mg Clomid cd 3-7, Ovidrel trigger, Beta 3/4/13: BFN.
DIUI#2 3/19/13, 50 mg Clomid cd 3-7, Ovidrel trigger, Beta #1 (14dpiui) 4/2/13: BFP!!!! 150. Beta #2 4/4/13: 420 Beta #3 4/8/13: 2691. Beta #4 4/15/13: 15,086
1st u/s 4/8/13 shows one gestational sac
2nd u/s 4/15/13 shows yolk sac, fetal pole and early heartbeat
3rd u/s 4/25/13: measuring right on track. Heart rate 148 bpm
A/S 7/22/13: IT'S A BOY!!
PAIF/SAIF Always Welcome
[IMG]http://i49.tinypic.com/2qmon5u.jpg[/IMG] [IMG]http://i225.photobucket.com/albums/dd243/laurakat24/turkeybaster-1.jpg"[/IMG]