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ALL. ABNORMAL. :(

PPL2011PPL2011 member
in TTC after 35

Well there you have it. Six Day 6 Blasts, any that would have been transferred in an IVF cycle without PGS, came back from testing ALL ABNORMAL. They were really bad, none that would even make it out of the first trimester. 

Gut punched and depressed. I have to pick myself up, but how?  

 

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Re: ALL. ABNORMAL. :(

  • brooklynesquebrooklynesque member

    I'm so sorry, PPL.  I wish you and I hadn't both been gut-punched today -- I'll lift my very strong cocktail to you tonight.

    6 abnormals sounds like bad luck; if you tried again you might well get a couple of normal embies.  When you're on the older side like we are even under the best of circumstances only 10 or 20 percent of eggs are genetically normal, so it is in some sense the luck of the draw.  Hugs as you figure out what to do next.

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  • irishgirl0525irishgirl0525 member
    I'm so sorry you didn't get better news. This is all very unfair.
    TTC since 3/2010. Me 41, DH-49. After 3 years, 6 IUIs and several IVFs we have finally have our beautiful baby girl, born on 11/7/13.



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  • QOTRQOTR member
    Oh no.  I'm so sorry.
    Me-41, Hubby-40.
    1st BFP-8/17/12!  Missed Miscarriage discovered @ 8 week US.  D&C.
    2nd BFP-2/13/13!  Blighted Ovum discovered @ 8 week US. Natural miscarriage.
    3rd BFP-5/22/13!  By early June, progesterone plummeting.  Another loss.
    August 2013 - started Donor Egg process, but surprise BFP with my own eggs.
    Dear Son born 5/28/14
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  • BeckyP005BeckyP005 member

    Wow. I am so sorry to hear this. What a day today. Big hugs :(

    ME:46 MH:44 DE IVF 2014
    Met with RE 4/11. 2 IUI's BFN. DE best option. Switched clinics to do "shared" program. Had to retake all tests and a mamm that put me behind and then on a DE waiting list for 12 months. Picked a donor!! (10/13/13) Got matched. Estimated transfer in December. After 2.5 years of patiently waiting I will finally cycle....can hardly believe it. DE cycle got cancelled. One of her tests came back positive.  Waiting for another donor. Donor picked!! (1/18/14)

    DE IVF #1 (4/26) BFN  DE FET #1 (6/4) BFP! Beta 1=339 Beta 2=852 Beta 3=9957 EDD 2/22/15!!


     

     

         imageimage 
         image   imageimage



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  • BAKERMOMHDSBAKERMOMHDS member
    imagebrooklynesque:

    I'm so sorry, PPL.  I wish you and I hadn't both been gut-punched today -- I'll lift my very strong cocktail to you tonight.

    6 abnormals sounds like bad luck; if you tried again you might well get a couple of normal embies.  When you're on the older side like we are even under the best of circumstances only 10 or 20 percent of eggs are genetically normal, so it is in some sense the luck of the draw.  Hugs as you figure out what to do next.

    This exactly.. you girls have been through so much, to have everything ripped away at the last minute. I think one of the hardest parts of IF is the "highs and lows".  I never, never let myself feel good about anything anymore...I'm to familiar with disappointment.

    It is super hard to pick yourself up, you will..eventually.  I never know the *how* but one morning, you'll wake up and find a plan that works for you.

    I'm sorry is never enough... BIG HUGS... to both of you...

    Me = 39 DH = 50 TTC (since 01/2009 after a short break, I stopped counting *cycles* in 2010)
    DX 2010 : Unknown Infertility , AMA
    HSG 2005 = Normal / HSG 2010 = Normal
    SA 2005 = Normal / SA 2010 /2012 = Slightly low count : motility, morphology GREAT!
    Chromosomal analysis, MTHFR, ANA's, Lupus, Protein C, Protein S, APCR = Normal 2011

    M/C : 2005 (7wk), 2010 (6wk), 2011 (7wk)

    8 IUI's 2010-2011 all BFN

    IVF/ICSI antagonist 01/2012 #1 = BFN

    IVF/ICSI antagonist long 06/2012 #2 = BFN

    IVF/ICSI/CGH MDLF New Clinic/New RE 11/2012 #3 = One beautiful boy blasty frozen PGS normal

    IVF/ICSI/CGH MDLF 02/2013 #4 = One more beautiful boy blasty frozen PGS normal

    FET 6/20 : One 5AA PGS normal transferred Beta 1 6/28 = 53.9 / Beta 2 7/1 = 220 / Beta 3 7/3 = 550!

    1 U/S  6w3d - Heartbeat 119 /  2 U/S - 7w5d- Heartbeat 169 / 3 U/S (OB) 8w5d - Heartbeat still great!

    Baby G welcomed into the world 3/7/2014

    SAIF / PAIF always welcome ****

     

    image

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  • 10-4LilBuddy10-4LilBuddy member
    I am so sorry.  Words are insufficient.  :(
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  • QzeesQzees
    Wow, I am so sorry.  Sending {{hugs}} your way.
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  • Lenox1975Lenox1975 member
    imageBAKERMOMHDS:
    imagebrooklynesque:

    I'm so sorry, PPL.  I wish you and I hadn't both been gut-punched today -- I'll lift my very strong cocktail to you tonight.

    6 abnormals sounds like bad luck; if you tried again you might well get a couple of normal embies.  When you're on the older side like we are even under the best of circumstances only 10 or 20 percent of eggs are genetically normal, so it is in some sense the luck of the draw.  Hugs as you figure out what to do next.

    This exactly.. you girls have been through so much, to have everything ripped away at the last minute. I think one of the hardest parts of IF is the "highs and lows".  I never, never let myself feel good about anything anymore...I'm to familiar with disappointment.

    It is super hard to pick yourself up, you will..eventually.  I never know the *how* but one morning, you'll wake up and find a plan that works for you.

    I'm sorry is never enough... BIG HUGS... to both of you...

    This.  I am so painfully sorry. 

    Me: 37 DH: 37 TTC since Jan 2012. RE consult and initial testing done in Aug 2012: SA fine, AMH 1.1 & HSG clear - on way to IUI but got BFP on 9/10/2012. m/c 10/3/2012 at 6w5d. BFP next cycle which was a c/p. IUI #1: Clomid 100mg 12/6= BFN. IUI#2 (unmedicated) Jan 2013 = BFN. Hysteroscopy 1/25/13. IUI#3 Clomid 100mg 2/23 = BFN IUI# 4: BFN. IVF #1 April 2013, BFP!  EDD 1/12/14 with Boy!
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  • Jacque SillsJacque Sills member
    I'm am so sorry, PPL.  Sending you (((hugs))) 
    Lilypie Trying to Conceive 15 to 80 day cycle tickers
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  • owlprofowlprof member
    I'm so sorry that you got this news.  This process stinks.
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  • HeatherIconHeatherIcon member
    So sorry. This process can be so unfair.
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  • HeathernStevenHeathernSteven member

    I am so sorry, I hope you find your path and ability to pick your self up, so sorry!

    image
    My Ovulation Chart


    Me: 41 DH: 46. We are TTC our 1st, started July '11,
    3 cycles clomid with Ob,
    1 cycle Tamoxifen with Ob,
    Diagnosed PCOS 11/5/12
    clomid, trigger & timed bd 12/12 BFN
    1st clomid IUI 1/4/13 BFN.
    2nd clomid IUI 2/13 cancelled didn't respond to clomid.
    3/15/13 scheduled laparoscopy & on bcp.

    May 10 IUI from injectibles - BFN 

    May 22 done with interventions it will either happen or it won't. 

    February 2014 No longer actively trying, but not preventing. 

    SURPISE BFP 4/2/2015!!!!!!!!!!

    Miscarriage 4/23/15

     

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  • happywifemomofonehappywifemomofone member
    I'm so sorry to read this news-Big (((hugs)))  I'm sure that when the timing is right (I know timing was right when you first started trying!), you will find a way forward closer towards your take home baby.
    TTC since 10/09 Me-43 DH-44 RE and testing 10/10-11/10, Recommending IVF 1/11 New RE AMA and DOR-DH low motility IVF #1.1 cancelled 3/11 due to poor response IVF #1.2 May 2011, one perfect 8-cell embryo, 3dt-BFN, IVF #2.1 Converted to IUI d/t poor response. New RE 9/2011. IVF 2.2 completed using HGH,EPP,DHEA, Q-10 and accupuncture. Transferred one 8-cell, grade one embryo on 10/19. BFP 10/31/11 Chemical pregancy on 11/2/11. Started stims for IVF #3, our final try, on 12-2-11. ET on 12/18. Transferred 3 Grade A embryos-BFFN Planning DE IVF, late March/early April- Donors ER expected to be 4/2-4/4. PAIF/SAIF welcome
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  • DawnHopeDawnHope member
    I am so sorry to hear this. I also am 41.5, so I truly understand the stress of each passing month.   Sending you strength, and my thoughts and prayers are with you.
    Me-42 DH-43 TTC #1 since 3/11
    HSG 7/11 showed possible blockage
    8/11 BFP, then early m/c  (Natural)
    9/11 blood tests reveal Factor V Leiden (heterozygous)
    11/11 Hysteroscopy revealed uterine septum, which was repaired
    12/11 1st round of Clomid (100mg)=BFN
    1/12 2nd round of Clomid (100mg)=BFN 
    2/12 Repeat HSG=All clear 
    2/12 IUI with injectables #1=BFN 
    3/12 natural cycle=BFN 
    4/12 IUI with injectables #2=C/P 
    7/12 IVF #1=30ER, 9F, 3T, 1 Frostie 7/29=BFP! 
    8/27/12 No Heartbeat. Waiting to M/C 
    9/13/12 D+C
    12/12 Operative Hysteroscopy 
    1/31/12  IVF#2 ...BFP 2/6 m/c 2/12 methotrexate due to presumed ectopic
    July '13 IVF #3: 13R, 10M, 8F=BFP
    1st Beta=549  2nd Beta 594 3rd Beta 422. M/C #5
    IVF#4 in November=BFP…TWINS!!!!!

    BabyFruit Ticker
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  • PPL2011PPL2011 member
    Thanks for your kind words everyone. My husband and I are devastated but we will try again.

     

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  • hollyweenORhollyweenOR member
    I'm so sorry. <3
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  • chucktgirlchucktgirl member
    I'm so sorry. Words can't even comfort at this point, I'm sure. I'm another 41.5. And in both of my previous IVF, ALL my embies (six total) also came back abnormal. I wish I knew how to help make you feel better. My husband and I are considering a last ditch IVF with no PGS. I don't have a lot of fight left in me. I hope you are able to find your inspiration. <hugs!>

    imageimageimageimageimageimageimageimage
    My BLOG: www.ivfbabyquest.wordpress.com -Update - old blog.

    PAIF/SAIF Welcome!
    Me: 42, Hubby: 35, TTC since Jan 2010. Dx: DOR due to advanced maternal age. Also: Hypothyroidism (100mcg Levothyroxin). Positive for MTHFR (hetero-C677T), Factor V Leiden, and Fragile X (on DH side). Taking pre-natal vitamins    .
    First natural PG 9/27/11; mc: 1/20/12
    First RE visit: 8/8/12, Saline Sonogram: 8/28/12, IVF injection class: 10/11/12, add FaBB Tab for FVL, +Vitamin D.
    IVF #1: 10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Prog- 0.3 The u/s showed 6 follicles in my right  & 9 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 10/21/12: Add Ganirelix SQ every morning.
    ER 10/28/12: 13 Retreived. 7 Mature. 6 Fertilized. 5 Made it to PGS. ET 11/2/12: CANCELED. All 5 came back from PGS as having "severe abnormalities."
    IVF #2: 1/7/13 Baseline: FSH- 8.8, 4 follicles in my right & 6 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 1/11/13: Add Ganirelix SQ every morning. hCG Trigger 1/16/13
    ER 1/18/13: 9 Retrieved. 5 Mature. 5 Fertilized. 2 Made it to PGS. ET 1/23/13: CANCELED. All embryos (he even sent the ones not growing) came back from PGS as having "multiple severe abnormalities."
    IVF #3:     NEW RE! 3/1/13 Baseline: FSH- 9.6, E2- 61, Prog- 0.94, 3 follicles in my right & 4 in my left. Rx: 150 Bravelle& 150 Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ.
    ER 3/11/13: 6R, 2M, 2F. Day 3: one 8 cell, grade 0.  Five day ET 3/16/13: one early blast, grade Fair. 3/24/13 AF came a day before beta. BFN
    IVF #4:     (Added acupuncture to this cycle.) 3/25/13 WTF & Baseline: FSH-11.8, E2- 56, Prog- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5 follicles in my right & 4 in my left. Rx: 225 Bravelle& 225 Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM.hCG Trigger 4/3/13 SQ.
    ER 4/5/13: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2 (Scale 0-best to 3-worst). Five day ET 4/10/13: two blastocysts (the 3rd stopped growing.) Beta 4/18/13: 2.5 BFFN. RE recommends we stop trying and focus on living childless, due to the extremely poor quality of my eggs.
    ***Decided to stop trying and live CFNBC. I couldn't adjust. So, six months later...
    IVF #5: Changed RE. Going to one of the big name clinics now. OWDU: 10/29/13. Update: HORRIBLE experience. Disgusted and distraught at their complete unprofessionalism and how much money and precious time they cost us. Sickening. Have now changed RE again. New Patient appt. 1/30/14.
    BFP! Out of nowhere, I got KU the old fashioned way! POAS 1/26/14 - Positive! FDLM 12/30/13. Beta #1 16dpo= 373. Beta #2 18dpo= 801. EDD 10/6/14
    2/4/14 1st U/S revealed a 5wk2day sac but no fetal pole. Started 200mgs of progesterone suppositories daily
    2/11/14 2nd U/S revealed a perfect 6wk1day "diamond ring" embryo with a beating heart! 138bpm! Add 1mg folic acid and 40mg Lovenox
    2/25/14 3rd U/S: perfect 8w1d embryo, 178bpm. 3/6 start spotting. 3/11 10w1d U/S shows no heartbeat. Scheduling D&C. The Stork has forsaken me again.
    IVF #5.2: New in-state RE. Supplement priming for 1.5 cycles prior to start of cycle, including DHEA 50mg (stopped 5/15), CoQ10 200mg 2x/day, L-Arginine- 1000mg 2x/day (stopped 6/5 due to cold sore!), myo-inositol- 2g 2x/day, melatonin- 3mg, and Neevo (prenatal for MTHFR).
    5/16/14 Day 2 bw cycle prior: FSH- 12.22, E2- 38.37, Prog- 1.35, LH- 9.46. 6/2/14 Day 19 bw: Prog- 23
    6/12/14 Baseline: E2- 122.7, Prog- 0.4. 5 follicles in left, 4 follicles in right. Start stims: 375IU Follistim & 150IU Menopur. 6/19 Increase Follistim to 425IU, Menopur still 150IU. 6/18 add Ganirelix. 6/23 Ovidrel trigger SQ. 6/25 ER: 8R, 8M, 5F naturally. Start Medrol & Doxy. 6/26 Start Endometrin. 7/2 Start Lovenox.
    7/8/14 Beta= 137.4 BFP!!! (My first from IVF!) E2- 1109, Prog- >60. Stop CoQ10, myo-inositol, and melatonin. 7/9 2nd Beta= 281.4. TSH- 2.70. Increasing Synthroid to 100mcg daily. 7/24 6w3d u/s measured 6w3d, hb: 121bmp! 8/5 8w1d u/s measured 8w3d, hb: 164bpm! Graduated from RE to OB. Now I just need to find an OB!
    EDD 3/18/15!

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  • GuennieGuennie member
    I know I'm new on here and I don't know everyone's story, but I am so so very sorry for what you are going through.  I just replied on another one of your posts and it just doesn't seem like enough.  I haven't been exactly where you are now (although I soon could be I guess since I am going to see an RE for the first time next month...) but I understand your pain and I am so glad you aren't giving up.  I wish I knew what to say to help you feel better but I know all too well it takes some time to pull yourself back up and find the strength to stay positive and hopeful.  I'm wishing you all the best.  xoxo
    Me:41, DH:41 Positive for MTHFR mutations- one copy C677T, one copy A1298C. One daughter born on Thanksgiving in 2013. Six losses.
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