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Lupron Inj. Question

jakraft837jakraft837
in Infertility

Day 2 of Lupron. yesterday, it hurt a bit afterwards and i noticed a small "bubble" under skin at injection site. I rubbed gently in circular motion for a few minutes and it went away.  Today, i injected slower and got same thing.

Is this normal?  Am i doing something wrong? Im not a newbie with doing shots, so not sure why this is happening.

~Jen
4/12: HSG All Clear
5-1-12: DX of PCOS
5-4-12: DH S/A all normal.
5-16-12: Offically start IUI#1-->Clomid(50mg) + Trigger + IUI + progesterone supplements=BFN
IUI #2-same treatment-->BFN
July IUI#3-same treatment--->BFN
Aug 22, 2012-Laparoscopy Found/Removed extensive endometreosis.
September 2012-IUI #4-Same treatment as before. BFN
October 2012-forced break/Surgery to remove abnormal cells in left breast.
November 2012-First Injects Cycle (IUI #5)! 225IU Follistim CD 3-5, then monitoring appointment. 20+ follier & e2 >2000-Mild OHSS
December 2012-#2 Injects + IUI#6): Beta 1/18/13-BFN!
Jan 2013-Starting IVF!!! BC starts Jan 17/Lupron on Feb 13/Stims on Feb 18/ER on March 1 IVF Protocol: Lupron 10 units in am until stimms. Then 5 units of Lurpon in am, 150iu of Follistim and 1 unit of Menopur in pm. Holding dosage throughtout since response has been great. Thought we would be freeze all due to OHSS, but ended up getting more follicles then expected! 14 total!!! 12 mature and 11 fertilized. Dr calls for a 5 day transfer!! :) Will freeze remaining.
image
With Love & Strength, Hope Grows!
WHEN, not IF!!!
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Re: Lupron Inj. Question

  • kflynn81kflynn81 member
    This may be a silly question but you're injecting the needle all the way in right? Like, you're not only putting half of it in the skin right?  Only reason I ask is because if you were doing that, it would seem a likely thing to happen to get a little bubble because you wouldn't be injecting it under all the top layers of the skin, it would only be under the very top most layer instead thereby probably causing a bubble. However, if the needle is all the way in then I guess its probably ok especially if the bubble goes away soon after. HTH!
    Me: 33, Endocrine issues & FVL       DH: 32, Nothing 
    NTNP 2009-2012         TTC since 2012:
    • Clomid, 2 IUI cycles, and 5 IVF cycles = BFN
    • FET #1   August 2013 = BFP!     EDD 5/11/14
    • Jack dx at 19w1d with Dandy Walker on 12/16/13
    • Severe Pre-e /HELLP set in Jack born sleeping at 20w1d on 12/23/13
    • FET #2 --July 2014  BFP!  ---  EDD  4/5/15

    Jack has handpicked his sibling up there :)

    My blog about IF and loss ... Kate's IF Blog

            Lilypie Angel and Memorial tickers 

                                                      

                                                                              Lilypie Pregnancy tickers


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  • BrideJackie11BrideJackie11 member
    I sorta had a similar thing happen.  It wasn't a bubble but just a little bump and went away 15 minutes later.  DH put the needle all the way in and injected.  I also felt a little bit of irritation (stinging).  When I started stims, DH did the lupron in my thigh- no problems there, no bump or irritation, just a little blood on occasion.

    <Image and video hosting by TinyPic
    Married June 2011 Dx: anovulatory due to prolactinoma (1.5cmx 1.5cm in 2006)
    April 2012: MRI- questionable cyst 8mg by 12mm in pituitary ; referred to RE by Ob-gyn after amenorrhea x 4+ months, provera ineffective, low estrogen level
    cycle 1: May 2012, clomid 50mg; cycle cancelled, thin lining, no response
    cycle 2: June 2012, femara 5mg; cycle cancelled, no response
    cycle 3: July 2012, femara 7.5mg; cycle cancelled (largest folli on Cd12 & cd 16: 11, lining 4)
    Repeat MRI July 25,2012- Cyst unchanged, likely old infarction.
    Aug. 8: met with RE, move to injectables if HSG and SA normal
    Aug. 23: HSG all clear; DH- perfect
    Switched to a new RE in early Sept. IVF here we come
    Genetic testing reveals: Fragile X- Intermediate risk/grey zone.
    IVF#1: ER 11/30: 14 retrieved, 10 mature, 7 fertilized. E2 prior to trigger 5200. Decision made to freeze 6 embryos and transfer later due to OHSS.
    IVF#1.2/FET #1: estrogen injects start 1/18, FET delayed to try to thicken lining. lining 5.4mm. FET- 2/18- transferred one 3AA expanded blast. BFP 5dp5dt. Beta #1- 2/27 9dp5dt- 102.27 beta #2 3/1: 147 :(, beta #3 3/4: 268 told to stop meds and let nature take its course. requested 4th beta (3/6); Beta hell for 2 months.

    FET # 2: endometrial scratch 5/6, added estrace vaginally and ASA to delestrogen and PIO. June 10- transferred one 4AA hatched embryo, BFP 4dp6dt, Beta 1 (9dp6dt) 187, Beta 2 (11dp6dt): 412; Beta 3 (15dp6dt ): 4452. U/S #1- one beautiful embryo with a heartbeat of 133 at 7 weeks.  8 weeks: heartbeat 156. EDD 2/26/2014: born 2-3-14 induced due to Pre-E and HELLP at 36w5d.

    12/1: met with RE to discuss trying for #2


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  • jakraft837jakraft837

    imageBrideJackie11:
    I sorta had a similar thing happen.  It wasn't a bubble but just a little bump and went away 15 minutes later.  DH put the needle all the way in and injected.  I also felt a little bit of irritation (stinging).  When I started stims, DH did the lupron in my thigh- no problems there, no bump or irritation, just a little blood on occasion.

    Yes, calling it a bump vs. a bubble also matches what is happening with me. Perhaps i'll try my thigh tomorrow.  They told me i could do my thigh or tummy, adn i have just always done my stomach because its easy.

    Yes, im putting needle all the way in.

    Thx!

    ~Jen
    4/12: HSG All Clear
    5-1-12: DX of PCOS
    5-4-12: DH S/A all normal.
    5-16-12: Offically start IUI#1-->Clomid(50mg) + Trigger + IUI + progesterone supplements=BFN
    IUI #2-same treatment-->BFN
    July IUI#3-same treatment--->BFN
    Aug 22, 2012-Laparoscopy Found/Removed extensive endometreosis.
    September 2012-IUI #4-Same treatment as before. BFN
    October 2012-forced break/Surgery to remove abnormal cells in left breast.
    November 2012-First Injects Cycle (IUI #5)! 225IU Follistim CD 3-5, then monitoring appointment. 20+ follier & e2 >2000-Mild OHSS
    December 2012-#2 Injects + IUI#6): Beta 1/18/13-BFN!
    Jan 2013-Starting IVF!!! BC starts Jan 17/Lupron on Feb 13/Stims on Feb 18/ER on March 1 IVF Protocol: Lupron 10 units in am until stimms. Then 5 units of Lurpon in am, 150iu of Follistim and 1 unit of Menopur in pm. Holding dosage throughtout since response has been great. Thought we would be freeze all due to OHSS, but ended up getting more follicles then expected! 14 total!!! 12 mature and 11 fertilized. Dr calls for a 5 day transfer!! :) Will freeze remaining.
    image
    With Love & Strength, Hope Grows!
    WHEN, not IF!!!
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  • Temp878586125009588Temp878586125009588 member
    I've had the bump happen a few times. I just rub and after a few min. it goes away. (My needle is going in all the way). I don't think it effected anything since I was suppressed. Tonight will be my last injection of Lupron, and I've been doing it since January 6th. 
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  • jakraft837jakraft837

    imageDaysie:
    I've had the bump happen a few times. I just rub and after a few min. it goes away. (My needle is going in all the way). I don't think it effected anything since I was suppressed. Tonight will be my last injection of Lupron, and I've been doing it since January 6th. 

    Not really related to my original post, but why have you been on it for so long?

    ~Jen
    4/12: HSG All Clear
    5-1-12: DX of PCOS
    5-4-12: DH S/A all normal.
    5-16-12: Offically start IUI#1-->Clomid(50mg) + Trigger + IUI + progesterone supplements=BFN
    IUI #2-same treatment-->BFN
    July IUI#3-same treatment--->BFN
    Aug 22, 2012-Laparoscopy Found/Removed extensive endometreosis.
    September 2012-IUI #4-Same treatment as before. BFN
    October 2012-forced break/Surgery to remove abnormal cells in left breast.
    November 2012-First Injects Cycle (IUI #5)! 225IU Follistim CD 3-5, then monitoring appointment. 20+ follier & e2 >2000-Mild OHSS
    December 2012-#2 Injects + IUI#6): Beta 1/18/13-BFN!
    Jan 2013-Starting IVF!!! BC starts Jan 17/Lupron on Feb 13/Stims on Feb 18/ER on March 1 IVF Protocol: Lupron 10 units in am until stimms. Then 5 units of Lurpon in am, 150iu of Follistim and 1 unit of Menopur in pm. Holding dosage throughtout since response has been great. Thought we would be freeze all due to OHSS, but ended up getting more follicles then expected! 14 total!!! 12 mature and 11 fertilized. Dr calls for a 5 day transfer!! :) Will freeze remaining.
    image
    With Love & Strength, Hope Grows!
    WHEN, not IF!!!
    Report Reply
  • JewelsW1980JewelsW1980 member

    I've had that happen but I think the time it happened I put the needle in diagonally vs straight in and it left the bubble on my skin.  As long as your body absorbs it you're fine.  Does it hurt after the first 2 minutes?

    Me- 32, DH- 32- TTC for 4 Years
    IUIs 1-6 BFN
    IVF #1= BFP- M/C
    FET- Beta#1: 69, #2: 482, #3: 1088, #4: 28,318, Ultrasound- 1 beautiful heartbeat
    It's a boy!

     BabyFruit Ticker

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  • Temp878586125009588Temp878586125009588 member
    imagejakraft837:

    imageDaysie:
    I've had the bump happen a few times. I just rub and after a few min. it goes away. (My needle is going in all the way). I don't think it effected anything since I was suppressed. Tonight will be my last injection of Lupron, and I've been doing it since January 6th. 

    Not really related to my original post, but why have you been on it for so long?

     

    I started in Jan. 6th to suppress for my FET that was originally supposed to happen last week. I had a cyst so they had to push it back a week, FET is tomorrow.

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  • Scoop77Scoop77 member

    Please take this with a grain of salt since I'm nothing even remotely approaching a medical professional, but from what I've read, the subcutaneous injections are supposed to absorb through the fat. So I don't think it's an issue as long as you're getting through the skin to that fat later.

    Might be worth bringing up to a nurse the next time you see one, though. Just in case I'm all full of beans.

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