LGBT Parenting

XP from TPR: DIUI Ladies...

Hi ladies!

I usually post on IF and Third Party Repro. Posted this yesterday and one of your fellow bumpies suggested I post it here as well. I should've thought of that! I hope you don't mind me "dropping by" :) TIA!!

 

DIUI Ladies...

Hi everyone & happy Friday!!!

Well we have officially started our cycle for DIUI #1. Started Clomid yesterday and I go in next Sat for our first monitoring appointment. It seems there are quite a few of you with DE experience but I am hoping for any input on DIUI.

1. Did you get a BFP?

2. How many cycles did you do?

3. What Cryobank did you use?

4. Medicated or unmedicated cycles?

Just trying to pass some time and gain some hope! This is our last shot at achieving a pregnancy (RE said he'll give it up to 5 tries). I know I am getting ahead of myself but of course due to past disappointment I can't help but be afraid that this doesn't work! Our staff is hopeful but then again they were hopeful for our IVF...So just hoping for some info and success stories to keep me sane! TIA!! 

TTC since June 2011
DX: DH (30) severe MFI, severely low count & low motility
Me (32): all clear
Appt with Urologist 5/21/12: exam, ultrasound, bloodwork all normal.
Testicular Biopsy with TESE on 6/8/12. good sperm found! (left side only) froze sperm, failed thaw test :(
Orientation for IVF/ICSI on 6/13/12. Waiting for the green light following biopsy results...results show adequate sperm production both sides.
2nd SA 6/18/12: sample is "adequate for ICSI"
Plan: IVF/ICSI July 2012!
ER: 7/26/12. 15 eggs retrieved, all mature.
TESE/TESA/aspiration from epididymis, no motile sperm found :(
froze all eggs, the saga of praying for good sperm continues.
8/3/12: 2nd opinion from MFI uro on biopsy slides. Suspects "partial late maturation arrest."
Plan: more SAs, third biopsy/TESE with frozen back-up either from DH or DS.
SA 8/17/12: Zero sperm
SA 8/23/12: Zero sperm
9/26/12: SPERM FOUND! 15 eggs thawed, 12 survived and were ICSI'd, only 3 fertilized normally. Refrozen as embies and will thaw in Nov. Please survive and grow!
All 3 survived the thaw on 11/15/12!
FET 11/17/12: transferred 2, one 4B, one 4C. Beta 11/30:BFFN
moving on to DS
DIUI#1 2/18/13,50mg Clomid cd 3-7, Ovidrel trigger, Beta 3/4/13: BFN.
DIUI#2 3/19/13, 50 mg Clomid cd 3-7, Ovidrel trigger, Beta #1 (14dpiui) 4/2/13: BFP!!!! 150. Beta #2 4/4/13: 420 Beta #3 4/8/13: 2691. Beta #4 4/15/13: 15,086
1st u/s 4/8/13 shows one gestational sac
2nd u/s 4/15/13 shows yolk sac, fetal pole and early heartbeat
3rd u/s 4/25/13: measuring right on track. Heart rate 148 bpm
A/S 7/22/13: IT'S A BOY!!
PAIF/SAIF Always Welcome
[IMG]http://i49.tinypic.com/2qmon5u.jpg[/IMG] [IMG]http://i225.photobucket.com/albums/dd243/laurakat24/turkeybaster-1.jpg"[/IMG]Image and video hosting by TinyPic
BabyFruit Ticker

Re: XP from TPR: DIUI Ladies...

  • Best of luck to you!

    1. Did you get a BFP?  Yes

    2. How many cycles did you do? 5

    3. What Cryobank did you use? Columbus Cryobiology

    4. Medicated or unmedicated cycles?

    #1 - Clomid 50mg + Trigger (4 follicles) - BFN

    #2 - Clomid 25mg + Trigger (2 follicles) - BFN

    #3 - Clomid 25mg + Trigger (2 follicles) - BFN

    #4 - Clomid 50 mg + Trigger (2 follicles) - BFP - m/c approx. 8 weeks

    #5 - Clomid 50 mg + Trigger + Progesterone (2 follicles) - BFP - twin boys

  • Loading the player...
  • 1. Yes!

    2. 5 (keep in mind that we're oldies-- my partner, who's carrying, was 38 when we started and is 39 now)

    3. California Cryobank -- expensive, but worth it, imo. Our friends used a cheaper bank and weren't getting the same motility we were. Also, at California Cryobank they gather a LOT of info about donors and only something like 1% of prospective donors are accepted.

    4. #1 Clomid; #2 & #3 Letrozole max dose for 10 days; #4 & 5 were hybrid cycles using Letrozole and Follistim (trigger shot). #4 was a BFP for us, but resulted in a missed miscarriage at around 9 weeks. #5 was a BFP and we're 17.5 weeks pregnant now.

    I've read that 4-6 cycles are the average for getting a BFP with an IUI. My partner has PCOS and that slowed us down. Your doc probably won't want to put you on as much stuff as we used. :)

    Good luck! 

    BabyFruit Ticker
  • Glad you popped in as you wait for you next steps. We don't use the term "DIUI" so it took me a minute to figure out what you meant. I also don't think there are that many of us that have used donor eggs, but there are one or two. Here are my answers:

    1. Yes!

    2. 1 (although we tried a few about three years ago with bfns, I don't always count those since so much changed between that time and this).

    3. California Cryobank -- I agree that it's more expensive, but worth it. They had our very specific donor criteria, have high standards, great customer service and I was really happy that since we bought 13 vials and I requested the highest count and motility they were happy send it first.

    4. No meds during follicular phase, progesterone (Endometrin) during luteal phase and through the first tri. I just stopped as we're almost 14 weeks pregnant now.

    I credit stress reduction, acupuncture, weight loss, healthy diet, having my hormones in check (including controlled hypothyroidism) and feeling really confident in my charting and insemination timing.

    Best wishes!

    Met 07/07/05, Wedding 07/07/07, Legal Marriage Ceremony 12/9/12, Baby Boy Born 08/09/13 Baby Birthday Ticker Ticker
  • I am sorry I am mobile so I am going to try and structure this to make sense.

    We got a BFP from a DIUI on our first go around with IUI.

    We used Cryogenic Laboratories and while on the cheaper side 450 per vial our sample was very high in counts.

    We used clomid and trigger.

    We now have happy and healthy fraternal 11 day old twin boys.

    Best of luck!
    M & M
    06/12 - BFP!!!!
    Beta #1 15dpo - 256
    Beta #2 18dpo - 1097
    6wk U/S on 07/02 ~ TWINS!!!
    EDD 02/21/13
    09/10/12 Found out it's two Boys!!!! Sam and Jake
    Jacob and Samuel born 1/29/13 at 36 weeks. photo F489900B-BB44-4C44-ACD1-ABB73509E3B2-9032-000005E7AE7EF53E.jpg Lilypie Premature Baby tickers
  • 1. Did you get a BFP? Yes

    2. How many cycles did you do? 4

    3. What Cryobank did you use? Xytex. I'm in the south and our RE's office limited us to 3 banks that are relatively close, so CA Cryo was not an option. Our donor motility was very good. It's also pretty expensive, but definitely worth it.

    4. Medicated or unmedicated cycles?

    1 unmedicated cycle with a trigger

    2 cycles on Clomid, 2 follicles for one, one follicle for the second

    1 cycle 5mg Femara 2 follicles, BFP with singleton

    Warning No formatter is installed for the format bbhtml
  • Thanks so much, ladies! Your stories helped ease my mind so I appreciate that. We are using CA Cryo so happy to hear some of you have had success with them. Here's hoping we have some success as well! Thanks again!
    TTC since June 2011
    DX: DH (30) severe MFI, severely low count & low motility
    Me (32): all clear
    Appt with Urologist 5/21/12: exam, ultrasound, bloodwork all normal.
    Testicular Biopsy with TESE on 6/8/12. good sperm found! (left side only) froze sperm, failed thaw test :(
    Orientation for IVF/ICSI on 6/13/12. Waiting for the green light following biopsy results...results show adequate sperm production both sides.
    2nd SA 6/18/12: sample is "adequate for ICSI"
    Plan: IVF/ICSI July 2012!
    ER: 7/26/12. 15 eggs retrieved, all mature.
    TESE/TESA/aspiration from epididymis, no motile sperm found :(
    froze all eggs, the saga of praying for good sperm continues.
    8/3/12: 2nd opinion from MFI uro on biopsy slides. Suspects "partial late maturation arrest."
    Plan: more SAs, third biopsy/TESE with frozen back-up either from DH or DS.
    SA 8/17/12: Zero sperm
    SA 8/23/12: Zero sperm
    9/26/12: SPERM FOUND! 15 eggs thawed, 12 survived and were ICSI'd, only 3 fertilized normally. Refrozen as embies and will thaw in Nov. Please survive and grow!
    All 3 survived the thaw on 11/15/12!
    FET 11/17/12: transferred 2, one 4B, one 4C. Beta 11/30:BFFN
    moving on to DS
    DIUI#1 2/18/13,50mg Clomid cd 3-7, Ovidrel trigger, Beta 3/4/13: BFN.
    DIUI#2 3/19/13, 50 mg Clomid cd 3-7, Ovidrel trigger, Beta #1 (14dpiui) 4/2/13: BFP!!!! 150. Beta #2 4/4/13: 420 Beta #3 4/8/13: 2691. Beta #4 4/15/13: 15,086
    1st u/s 4/8/13 shows one gestational sac
    2nd u/s 4/15/13 shows yolk sac, fetal pole and early heartbeat
    3rd u/s 4/25/13: measuring right on track. Heart rate 148 bpm
    A/S 7/22/13: IT'S A BOY!!
    PAIF/SAIF Always Welcome
    [IMG]http://i49.tinypic.com/2qmon5u.jpg[/IMG] [IMG]http://i225.photobucket.com/albums/dd243/laurakat24/turkeybaster-1.jpg"[/IMG]Image and video hosting by TinyPic
    BabyFruit Ticker
  • imagemelkel559:
    Thanks so much, ladies! Your stories helped ease my mind so I appreciate that. We are using CA Cryo so happy to hear some of you have had success with them. Here's hoping we have some success as well! Thanks again!

    Hey there, glad you posted over here! Like I said on TPR, we used CA Cryo too, while we liked some of the smaller banks more, we just couldn't find the right donor. I think since we had to use an egg donor too, in which choice is so limited (we had 60 to choose from and probably half were instant 'no'), we felt like CA Cryo was a candy store with all the choice!

    Also the packet they send after your bfp is nice and professional. Since we did ivf we only needed one vial so cost was as big a deal (again, after our egg donor this felt like a drop in the bucket cost wise).

    Anyhow, I wanted to add though that I'm sorry you find yourself here, I can only imagine how hard it must be when your partner is male and had IF issues...for most of us here, it's a given to use DS (though it still is a 'third party' in the process). Take care and lots of luck to you!!!

    Lil'mamaz was born on Aug 21, 2014! She's PERFECT!

    It's been a long road to here...
    Me (43) and J (45) - same sex couple. And we don't feel 40+!
    June'12 - First RE Visit
    Sept. '12 - Tubes removed
    Dec. '12 - Donor Egg/Donor Sperm IVF Cycle - 4 good embies!
    Dec. '12 - Fresh transfer, BFP! EDD 8/29/13
    Mar. '13 - Missed m/c at 16w1d, baby boy stopped growing at 15w4d
    Loss due to umbilical cord clot...baby was perfect. :(
    Jul '13 - FET#1 - c/p
    Sept. '13 - FET#2 - BFN
    Dec.' 2, 2013 - FET#3 with our last chance embie - BFP!!!
    Dec' 26, 2013 - hb!!
    EDD 8/20/14 with a baby girl!
    Little S was born on 8/21/14 - 8lb, 14 oz and 20 inches long.
    We live in Seattle and used SRM for our donor egg IVF cycle


    imageimageimageimage

  • image2MamazInSeattle:

    imagemelkel559:
    Thanks so much, ladies! Your stories helped ease my mind so I appreciate that. We are using CA Cryo so happy to hear some of you have had success with them. Here's hoping we have some success as well! Thanks again!

    Hey there, glad you posted over here! Like I said on TPR, we used CA Cryo too, while we liked some of the smaller banks more, we just couldn't find the right donor. I think since we had to use an egg donor too, in which choice is so limited (we had 60 to choose from and probably half were instant 'no'), we felt like CA Cryo was a candy store with all the choice!

    Also the packet they send after your bfp is nice and professional. Since we did ivf we only needed one vial so cost was as big a deal (again, after our egg donor this felt like a drop in the bucket cost wise).

    Anyhow, I wanted to add though that I'm sorry you find yourself here, I can only imagine how hard it must be when your partner is male and had IF issues...for most of us here, it's a given to use DS (though it still is a 'third party' in the process). Take care and lots of luck to you!!!



    Thanks for the insight and for your thoughtful words as well. Yes, the MFI thing has been incredibly hard. It took us some time to get here but now we are both in 100 percent. Like all of us, we just want to start a family! GL to you too!
    TTC since June 2011
    DX: DH (30) severe MFI, severely low count & low motility
    Me (32): all clear
    Appt with Urologist 5/21/12: exam, ultrasound, bloodwork all normal.
    Testicular Biopsy with TESE on 6/8/12. good sperm found! (left side only) froze sperm, failed thaw test :(
    Orientation for IVF/ICSI on 6/13/12. Waiting for the green light following biopsy results...results show adequate sperm production both sides.
    2nd SA 6/18/12: sample is "adequate for ICSI"
    Plan: IVF/ICSI July 2012!
    ER: 7/26/12. 15 eggs retrieved, all mature.
    TESE/TESA/aspiration from epididymis, no motile sperm found :(
    froze all eggs, the saga of praying for good sperm continues.
    8/3/12: 2nd opinion from MFI uro on biopsy slides. Suspects "partial late maturation arrest."
    Plan: more SAs, third biopsy/TESE with frozen back-up either from DH or DS.
    SA 8/17/12: Zero sperm
    SA 8/23/12: Zero sperm
    9/26/12: SPERM FOUND! 15 eggs thawed, 12 survived and were ICSI'd, only 3 fertilized normally. Refrozen as embies and will thaw in Nov. Please survive and grow!
    All 3 survived the thaw on 11/15/12!
    FET 11/17/12: transferred 2, one 4B, one 4C. Beta 11/30:BFFN
    moving on to DS
    DIUI#1 2/18/13,50mg Clomid cd 3-7, Ovidrel trigger, Beta 3/4/13: BFN.
    DIUI#2 3/19/13, 50 mg Clomid cd 3-7, Ovidrel trigger, Beta #1 (14dpiui) 4/2/13: BFP!!!! 150. Beta #2 4/4/13: 420 Beta #3 4/8/13: 2691. Beta #4 4/15/13: 15,086
    1st u/s 4/8/13 shows one gestational sac
    2nd u/s 4/15/13 shows yolk sac, fetal pole and early heartbeat
    3rd u/s 4/25/13: measuring right on track. Heart rate 148 bpm
    A/S 7/22/13: IT'S A BOY!!
    PAIF/SAIF Always Welcome
    [IMG]http://i49.tinypic.com/2qmon5u.jpg[/IMG] [IMG]http://i225.photobucket.com/albums/dd243/laurakat24/turkeybaster-1.jpg"[/IMG]Image and video hosting by TinyPic
    BabyFruit Ticker
  • No known fertility issues.

    IUI #1 - 100mg clomid, trigger, prometrium - BFN

    IUI #2 - same as above - chemical pregnancy

    IUI #3 - same as above - BFP - DD#1

    2nd child

    IUI #1 - 100 mg clomid, trigger, prometrium - BFP - twins due in July

    Warning No formatter is installed for the format bbhtml
  • No known medical issues.

    My wife went first:

    6 At home ICIs
    9 single IUIs none medicated

    No pregnancies

    My turn
    1 backtoback IUIs not medicated
    2 backtoback IUIs not medicated
    3 backtoback IUIs not medicated
    4 backtoback IUIs not medicated
    5 backtoback IUI clomid low dose 25?
    6 backtoback IUI clomid 50? BFP

    baby 2 only 10 vials of retired donor and want as many siblings as possible so we were doing 6 single IUI to get to IVF. Didn't expect to get pregnant so quickly. Neither were medicated, I'm still nursing my son.

    1 single IUI
    2 single IUI BFP

    Bank CCB
    Lilypie Second Birthday tickers BabyFruit Ticker
  • Thanks for sharing this me and my husband are on our 3 doner IUI and this has given me great hope. Much love xx

    Trying to Conceive since Aug 2011
    Diagnosed with severe male factor IF we got no swimmers
    First dIUI Dec 7 2012 = BFN
    Second dIUI Jan 9 2013 = BFN
    Third dIUI with clomid 50mg Feb 5 2013
    Forth dIUI with clomid 100mg dIUI Early March
    Here is to a New Year!
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