Trouble TTC

Met with my RE... Now What?

Here's a little background. My OBGYN works with a fertility clinic (there are none too close to me). I've all my testing done through my gyn and it all came back normal, and DH's SA came back great.

 So today I met with the RE to go over everything and make a plan. So he basically gave me all my options and gave me the pros and cons of them all. 

 The 2 options he gave that me and DH are comfortable with at the moment are Clomid + IUI, and injectibles + IUI . The RE says he would do 3 cycles of Clomid + IUI before moving on to injectibles, or we could just go right into injectables. 

Here are my questions. We discussed the monitoring on Clomid and he does monitor it very closely, but just wondering, what is the standard appropriate amount? I don't want to mess with Clomid unless I know I am getting the absolute best care. 

If we decided to go ahead and go right into injectables, obviously our chances of conceiving are better, so why wouldn't we? There must be some downside or else, why would he have given Clomid as an option if we didn't want to jump right into them. 

 I also just wanted to thank everyone here, because even though I still have questions, I felt pretty prepared going into my appointment. I owe that to all the knowledge I've learned from this board. 

Re: Met with my RE... Now What?

  • The standard monitoring for Clomid is 

    CD3 ultrasound/blood work

    CD11-12ish ultrasound/ blood work

    7DPO p4 levels (progesterone) 

     

    I've only been on two rounds of Clomid and have not responded to either of them, our next step is one more round of 150mg of Clomid w/Ovidrel trigger shot. So I don't have any experience with injectables yet, but I wanted to wish you good luck!  

    ***************SIGGY WARNING***************
    DX: PCOS and Endometriosis 
    TTC since May 2011
    HSG normal
    Hubs SA- Normal June 2012
    Aug. 2012: 50mg Clomid: No Response
    March 2013: 100mg Clomid: No Response
    July 2013: 5mg Femara+Ovidrel+TI--BFN
    August 2013: 10mg Femara+Ovidrel+TI--BFN
    Natural cycles Sept & Oct.--BFN
    Nov/Dec: 10mg Femara+Ovidrel+TI--BFN
    Jan 2014: 10mg Femara+Ovidrel+TI--BFN
    Feb: Benched due to cysts.
    March: Benched w/cysts.
    April: Femara+Follistim+Ovidrel+Prometrium
    BFP on Mother's Day 2014!! 
    EDD: January 20, 2015
    6week scan: TWINS!!!!!
    16w: Baby A is Stubborn, Baby B is a GIRL!
    20 week scan: TEAM PURPLE!
    The babies were born on December 16, 2014 at 35 weeks! They are home and doing well!

    image 


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  • I think the reason why most people choose Clomid/Femara + IUI is the cost factor. Injectables are crazy expensive if you have to pay out of pocket.

    I choose to do 4 rounds of Clomid, and now I'm on round #2 of Femara but we did add injects to help push my ovaries since I'm a slow grower.

    One 300iu Gonal-f pen set me back $278! (I did get 5 injects out of it.) I will get back $30 because they have a rebate right now.

    I'm not sure if we'll be able to do an all inject cycle due to the cost since we are OOP.

    I also feel that RE's would rather do the least invasive (and cheaper) protocols first, at least mine did, before jumping into something more expensive.

    I hope this helps! And good luck!

    photo 46122502-649c-4d9b-a99e-dc22cf009d51_zpsf72c5124.jpg photo mason4_zps7f19f81c.jpg

    Baby Birthday Ticker Ticker TTC 07/2010, Dx with PCOS 11/2011, H's S/A= Perfect!!! HSG= both tubes clear!
    Round #6- 7.5mg Femara+ .5mg Dex+ 75iu Gonal-F+ hCG trigger+ IUI=BFP!!!
    Beta #1(14dpo)- 94 Beta#2(22dpo)- 1,619 Beta#3 (28dpo)- 11,396!!!

    Just a Little Blog

  • imageShortie24:

    I think the reason why most people choose Clomid/Femara + IUI is the cost factor. Injectables are crazy expensive if you have to pay out of pocket.

    I choose to do 4 rounds of Clomid, and now I'm on round #2 of Femara but we did add injects to help push my ovaries since I'm a slow grower.

    One 300iu Gonal-f pen set me back $278! (I did get 5 injects out of it.) I will get back $30 because they have a rebate right now.

    I'm not sure if we'll be able to do an all inject cycle due to the cost since we are OOP.

    I also feel that RE's would rather do the least invasive (and cheaper) protocols first, at least mine did, before jumping into something more expensive.

    I hope this helps! And good luck!

    This. Also, I think it would be better to see how you react to the Clomid alone because if you have a good response to it, there's really no need for the injects. You could end up overstimulating.

  • I just had my consultation to move on to injectables next cycle. 

    The medicine is more expensive and there is more monitoring, which is more expensive.

    For clomid I go in on CD3, CD11, IUI, and 7DPO bloodwork.

    The schedule they gave me for injectables was CD2 -- BW+US, CD4 -- BW, CD6--BW+US, then monitoring continuing every two-three days while stimming until we're ready to trigger. That's 4-6 check-ins or so before even having IUI. 

    I would definitely try Clomid first.

    Me: 31, DH: 33 Dx PCOS
    5/12 -- HSG, blocked left tube cleared, cycle canceled b/c of cyst
    6/12 -- Clomid 100mg + TI -- BFN
    7/12 -- Clomid 100mg + TI + Progesterone -- BFN
    8/12 -- Benched with a cyst
    10/12 -- Clomid 100mg + TI -- BFN
    11/12 -- Clomid 100mg + Trigger + TI -- BFN
    12/12 -- Clomid 100mg + Trigger + IUI -- BFN
    1/13 -- Clomid 100mg + Trigger + IUI -- BFFN
    2/13 -- Clomid 100mg + Trigger + IUI -- BFP!!!
    Beta 1=168 Beta 2=745 Beta 3=1700+
    EDD 10/25 BabyFruit Ticker
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  • This all makes a ton of sense, I'm glad I asked. I feel a lot better about going with clomid and IUI. I guess I just am scared of clomid because of all the side effects I hear, but obviously injectables come with there own laundry list as well.
  •  

    I am exactly where you are right now. I'm unexplained and our RE gave us the same choice. He mentioned the FASTT study that gave statistics for Clomid/IUI and injects/IUI. Here's a web page with a summary from the study. It's long but the details of the study are in the "Comparison of Different Treatments for Unexplained Infertility" section at the bottom.

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2505167/

     I chose Clomid/IUI for the reasons PP mentioned. Looking at the study, injects didn't increase the chances in a drastic way to make me lean that direction. GL to you. I hope Clomid/IUI does the trick!  

    Dawsons creek cast Pictures, Images and Photos image
    TTC since Jan 2012

    Me (28) DH (28)

    Dec 2012 Testing Complete: Me: Blood tests look great HSG "beautiful" DH: SA = normal Unexplained?

    PAIF/SAIF welcome!
  • We also just went through this and did Clomid + IUI.  I didn't experience any side effects from Clomid, they usually start you on the lowest doseage to see how your body responds.  I think I only had one mature follicle but it was a good size so they triggered me and I should know by Monday if it worked.

     

  • imagelaurid75:
    We also just went through this and did Clomid IUI.nbsp; I didn't experience any side effects from Clomid, they usually start you on the lowest doseage to see how your body responds.nbsp; I think I only had one mature follicle but it was a good size so they triggered me and I should know by Monday if it worked.
    nbsp;
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