Success after IF

Starting Femara

I've been a little MIA lately since waiting to finally see the RE. I had my first appt last week after failing my last 2 cycles on clomid and having a couple of med free cycles. My RE seems nice and wants to start me on Femara. I'm just a little confused though. While on clomid this time around, I did ovulate but never concieved. I'm not sure how Femara will help. My RE stated I would respond better but it seems that I responded to clomid because I ovulated. Does this seem odd to anyone else that she wouldn't do a post coital test or something else to determine why conception wasn't occurring even after ovulation?
image DS 7.6.2011 TTC#2

Re: Starting Femara

  • From what I've read around here post coital tests aren't very accurate and a lot of REs don't do them. Mine does not.
    Clomid can thin your lining so I have heard a lot of REs prefer Femara over clomid. Plus Femara has less s/e.

    If clomid hasn't worked for you then I think it's a good idea to try something different. Sorry I can't see your siggy as I'm on my phone so I don't know your history.

    Are you upset because it seems like your RE isn't finding the problem, instead is just throwing pills at you hoping they will work?
    Diagnosed MFI- low sperm count  
    DS-Born 7/27/11 After 2 years of IF we have our little man
    TTC#2 January 2013
    11 Medicated cycles gave us
    B/G Twins born 10/8/14 @ 32 weeks
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  • It's ok, my history isn't in my siggy. I have unexplained anovulation. I concieved after 4 cycles on clomid with DS a yr and a half ago being monitored by my OB. I tried my last 2 cycles of clomid TTC2 at which time I decided I should see a RE. I had my first appt and I guess I was expecting more? I just didn't understand what a difference Femara would make if I was already ovulating on clomid and figured there was something else going on and thought she would do other tests.
    image DS 7.6.2011 TTC#2
  • imageCwhitaker27:
    It's ok, my history isn't in my siggy. I have unexplained anovulation. I concieved after 4 cycles on clomid with DS a yr and a half ago being monitored by my OB. I tried my last 2 cycles of clomid TTC2 at which time I decided I should see a RE. I had my first appt and I guess I was expecting more? I just didn't understand what a difference Femara would make if I was already ovulating on clomid and figured there was something else going on and thought she would do other tests.
    Many REs (mine included) won't do more than six total Clomid cycles in a lifetime. Clomid can have lasting effects on your lining. Your RE is smart to change it up. My RE usually won't do more than three cycles of a certain intervention before moving on because after three cycles you usually reach a point of diminishing returns. GL!
    image
    Unexplained Infertility

    After two Clomid cycles, three injectable IUI cycles, two IVFs, two miscarriages, and one lap surgery, IVF #2 has brought us our little boy!

    Baby Birthday Ticker Ticker

    TTC #2
    After months of being postponed or cancelled, FET #1.3 (Natural FET) brought us twin girls!

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    Surprise! Baby #4 is due in March!
  • imageDragonfly1226:
    imageCwhitaker27:
    It's ok, my history isn't in my siggy. I have unexplained anovulation. I concieved after 4 cycles on clomid with DS a yr and a half ago being monitored by my OB. I tried my last 2 cycles of clomid TTC2 at which time I decided I should see a RE. I had my first appt and I guess I was expecting more? I just didn't understand what a difference Femara would make if I was already ovulating on clomid and figured there was something else going on and thought she would do other tests.
    Many REs (mine included) won't do more than six total Clomid cycles in a lifetime. Clomid can have lasting effects on your lining. Your RE is smart to change it up. My RE usually won't do more than three cycles of a certain intervention before moving on because after three cycles you usually reach a point of diminishing returns. GL!

    I agree with all of this.  Femara worked for me - give it a chance. FX for you!

    TTC with PCOS since November 2009
    IUI#1 Femara/Ovidrel (cd 3-7) = BFP, m/c
    IUI#2 Femara/Ovidrel (cd 5-9) = BFN
    IUI#3 Femara/Ovidrel (cd 3-7) = BFP!
    beta #1 11/23 = 270, P4 = 75
    beta #2 11/28 = 2055
    Our daughter E was born 7/29/2012!
    Surprise, our 2nd daughter P was born 5/22/14!
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  • Clomid tends to thin the lining of the uterus whereas Femara does not so that works in your favor.  You don't know if maybe the egg did fertilize but just never implanted. 

    Also, how many follicles were you getting with clomid? 

    I ovulate on my own but used clomid for a ton of cycles and only conceived with one of them and then I miscarried.  I used Femara for two cycles and got pregnant my second cycle (in which I used Femara and some Follistim).  Femara also has lower instances of miscarriages.

    I hope it works for you.

    Kelly, Mom to Christopher Shannon 9.27.06, Catherine Quinn 2.24.09, Trey Barton lost on 12.28.09, Therese Barton lost on 6.10.10, Joseph Sullivan 7.23.11, and our latest, Victoria Maren 11.15.12

    Secondary infertility success with IVF, then two losses, one at 14 weeks and one at 10 weeks, then success with IUI and then just pure, crazy luck.  Expecting our fifth in May as the result of a FET.

    This Cluttered Life

  • All of the PPs have given great advice! Just wanted to say good luck to you!
    Me: 37 DH: 40 TTC since 9/09
    #1 BFP 1/10/11; missed m/c discovered 7w5d
    IF Dx: Endo, hetero MTHFR mutation, poor morphology
    #1 IUI: 1/18/12 = BFN
    #1 IVF/ICSI 4/2/12 = 2 x 7-cell and 1 x 5-cell transferred (3dt) = BFP!!
    H was born at 41w2d on 12/29/12 - be still my heart!
    #2 IVF/ICSI 1/19/14 = 2 x 8 cells transferred (3dt) = BFP!! EDD 10/09/14
    M&W born at 37 weeks on 9/18/14 - I am the momma of 3 boys!!!

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  • imageitsmevkb:
    Clomid tends to thin the lining of the uterus whereas Femara does not so that works in your favor.nbsp; You don't know if maybe the egg did fertilize but just never implanted.nbsp; Also, how many follicles were you getting with clomid?nbsp;I ovulate on my own but used clomid for a ton of cycles and only conceived with one of them and then I miscarried.nbsp; I used Femara for two cycles and got pregnant my second cycle in which I used Femara and some Follistim.nbsp; Femara also has lower instances of miscarriages.I hope it works for you.

    I usually had between 3 and 4 follies on clomid.
    image DS 7.6.2011 TTC#2
  • Thanks for the clarification and support ladies. Hoping Femara does the trick. I always hear good things about it, especially on this board.
    image DS 7.6.2011 TTC#2
  • Femara works very well for me while Clomid barely works at all.  It's also normal for a certain protocol to take a few cycles before working.  It took 3 rounds of Femara to conceive DS and 3 to conceive this baby.

    A lot of things can affect whether you conceive or not.  Maybe you respond better to Femara with better quality eggs, more follicles and a better lining.  I don't think it would hurt anything to do a post coital test but there could be many reasons (that are unknown) as to why you didn't conceive in prior cycles.  Good luck!

    Married 9/19/09
    Me (32) Dx PCOS, DH (32) SA = Normal/mild morph issues
    TTC#5 July 2017 - 3rd cycle TTC = BFP on 11/12/17 at 9dpo Beta #1 = 96 at 13dpo - Beta #2 = 207 at 15dpo
    TTC#1  starting Nov. 2009
    3 rounds of Clomid + TI and 3 rounds of 7.5 mg Femara + IUI before our BFP on 11/8/10 at 12dpiui
    TTC #2 3rd cycle of Femara 7.5mg+Ovidrel+TI = 4 follies = BFP on 10/12/12 
    TTC#3 July 2014 - Metformin +TI = BFP at 9dpo - Twins, one baby lost at 5.5 weeks 
    Macy Annabelle born at 37w4d on 4/29/15.  Diagnosed with Cri du Chat and passed away on 6/6/15.  Forever in our hearts.
    TTC#4 3rd cycle of Metformin + Femara 7.5mg+Ovidrel+TI = 3 follies = BFP on 12/24/16
    BabyFruit Ticker
  • Hi everyone,

    I'm new here and hubby and I have been TTC for 27 months now. We started seeing a fertility specialist in August. We went through all the testing and were diagnosed with unexplained infertility, so he gave us a prescription for 6 months worth of Letrozole/Femara and sent us on our way. Just said to let him know how it goes. Is this normal? I've been seeing a lot of posts regarding Letrozole/Femara and most women are monitored while on it, having ultrasounds each cycle to measure the follicles. He never mentioned any of this to us. Is this something we should be requesting to have done? So far we've gone through 2 unsuccesful cycles with the letrozole and I will be starting the third cycle on it tomorrow.

    Thanks in advance!

  • imageamberger31:
    Hi everyone,I'm new here and hubby and I have been TTC for 27 months now. We started seeing a fertility specialist in August. We went through all the testing and were diagnosed with unexplained infertility, so he gave us a prescription for 6 months worth of Letrozole/Femara and sent us on our way. Just said to let him know how it goes. Is this normal? I've been seeing a lot of posts regarding Letrozole/Femara and most women are monitored while on it, having ultrasounds each cycle to measure the follicles. He never mentioned any of this to us. Is this something we should be requesting to have done? So far we've gone through 2 unsuccesful cycles with the letrozole and I will be starting the third cycle on it tomorrow.Thanks in advance!

    You might have better response posting on the main board than on this persons thread. But no, that's not normal and not safe. I'd find a new RE.
    TTC with PCOS since November 2009
    IUI#1 Femara/Ovidrel (cd 3-7) = BFP, m/c
    IUI#2 Femara/Ovidrel (cd 5-9) = BFN
    IUI#3 Femara/Ovidrel (cd 3-7) = BFP!
    beta #1 11/23 = 270, P4 = 75
    beta #2 11/28 = 2055
    Our daughter E was born 7/29/2012!
    Surprise, our 2nd daughter P was born 5/22/14!
     image
    imageImage and video hosting by TinyPicimage
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    imageimageimage
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