Please explain EPP and antagonist protocol

J&D2007

Can someone give me a rundown on these protocols? I've had long lupron protocol and MD lupron protocol. Both bfn, only 4 or 5 eggs produced with each (all mature). AFC was 20, FSH around 6. Unexplained. Thinking of seeing a new RE and asking what protocol could be used, but I don't understand these two protocols. TIA for your help.

sunflowers4AC

I did antagonist protocol my first IVF. It was BCP for 21 days, then stim with Gonal F and Menopur each day. After 5 or 6 days we added in Ganirelix each day until trigger. I did produce more mature eggs, our problem was they didn't fertilize so that is why cycle 2 we did ICSI.

new+tothis

I did an antagonist protocol. I'll give you my schedule:

Start with Menopur and Follistim. I was supposed to add Ganirelix in on day 5 but I needed it a day earlier at day 4. I continued this until trigger (which I did on day 10 but clearly that varies). For all my IUIs I was a slow grower so day 10 is good for me.

I did take birth control pills before stimming but that was because I don't cycle regularly on my own and so I could start when they had an opening. I took them for about 2 weeks. Estrogen and Progesterone support are more important with the antagonist protocol.

I have low AMH but normal everything else. When you do this protocol you can use Lupron to trigger. I used a combination of Lupron and HCG to trigger so it was not the normal schedule. I did HCG 35 hours pre-ER then Lupron 34 hours pre-ER and again 22 hours pre-ER. 

Maybe Joleisa

My 1st IVF we used the Antagonist protocol: BCPs for 21 days, stimmed with Gonal-F & Menopur and then added in Cetrotide when a couple of the follicles got bigger so that some smaller ones could catch up. During this protocol my estrogen was doubling nicely, but by trigger day it had started to decline. The next cycle we tried MDLF to avoid that happening again and that cycle was better than my first cycle. 

Good luck moving forward. 

J&D2007

HarleyP11:

JD2007:

Can someone give me a rundown on these protocols? I've had long lupron protocol and MD lupron protocol. Both bfn, only 4 or 5 eggs produced with each all mature. AFC was 20, FSH around 6. Unexplained. Thinking of seeing a new RE and asking what protocol could be used, but I don't understand these two protocols. TIA for your help.

Hi! On the mobile version I can't read the whole titles of the posts, did u ask about the estrogen priming protocol? I'm doing that now and would be happy to answer any questions :

 

thanks! I really don't know anything about it. What purpose is it used for? In those that haven't responded to other methods? People with certain diagnoses? Is it supposed to get more eggs? Better quality? What would a normal protocol look like? Thanks!