Infertility Veterans

Beta-3 Integrin biopsy. Check.

Just had my 2nd endometrial biopsy of this incredible journey. This time to check for the beta-3 intergrin.

I must say that out of all the HSGs, procedures, retrievals, surgeries I've had. Endometrial biopsies for me are the worst, physically.

**squeamish warning**

I can handle it, but barely. I really have to do some deep breathing and hand wringing to get me through. It feels like someone is twisting a screw into your uterus for 45 secs to a minute. Seriously. It feels just like that.

**done squeaming**

So my home clinic packed it up and sent it off to the specialty lab. Hopefully I'll hear from CC.RM in the next few weeks about the results.

-------

"Fun" Question of the Day: What's your least favorite procedure?

BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08
TTC #1 since 1/10
DX: Unexplained/??? MFI issues

Our lil' lost sparks:
5w3d loss 7/30/10 - EDD March 2011
8w loss 4/15/11 - EDD November 2011
8w3d loss 8/2/12 - EDD March 2013
4w c/p loss 10/29/12 - EDD July 2013

Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
RPL testing all normal, Karyotyping normal

Moving on to IVF.

IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14

After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14
We are so in love with her.

"I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

Everybody is welcome!!!

Re: Beta-3 Integrin biopsy. Check.

  • That sounds awful! There should be a mandatory issuance of mucle relaxers/pain killers/whiskey or a cocktail of all of those for these procedures we endure!! FX your results are good and you don't have to wait too long for them.

     

    QOTD: So far the worst has been the HSG. I almost came off the table and slapped the nurse when she told me it was going to be a period like cramp. Oh, I'm sorry. I'm in the throes of my uterus exploding and my tubes spontaneously combusting. I'll let you know when I get to the "period like cramping". I don't know why it was so awful for me but I would demand some kind of drugs if I ever had to do it again. **If you're reading this and have never had a HSG, please don't let me scare you. It's not this bad for most people. Call me lucky.**


    ***signature & ticker warning***


    Me: 30 ~ Stage IV Endo ~ AMH .38 ~ AFC 8
    AMH .97 as of 4/2012! ~ AMH 1.63 as of 4/2013!?!

    Him: 29 ~ perfect swimmers

    Laparotomy w/partial oophorectomy 8/2009 to remove cysts/endo.
    Stopped BCP 4/2010.
    Multiple clomid rounds from 11/2010 to 6/2011. ~ All BFN
    IUI w/clomid 7/2011. IUI w/clomid & injectables 11/2011 & 1/2012. ~ All BFN

    IVF:EPP 5/2012 ~ (4R, 3M, 2F w/ICSI). Both embryos txfrd. ~ BFN
    BCP to manage endo from 10/2012 to 12/2012.
    FET w/donor embryos #1: 10/2013 Cancelled
    FET w/donor embryos #1.2: 11/2013
    ~ ET of 2 beautiful blasts on 11/27.
    Beta 1: 503(12dp5dt) Beta 2: 1035(14dpt) Beta 3: 3001(16dpt)
    Beta 4: 8503(19dpt)
    Twins with an EDD of 8/15/14! Team Purple
    G&B born 6/30/14 at 33w3d via emergency c/s.


    If you're wondering about my avatar...it's a fried pickle chip shaped like a fetus!


    image

    image
  • Loading the player...
  • EEk, that sounds awful. I'm so glad that's over with for you. Makes me squirm reading it, and I've never even had that done!

    FX for good and fast results for you!

    As for awful IF procedures, my HSG was a piece of cake for some reason. So I assumed my first SHG would be the same. No. No, it wasn't. It hurt so much I wanted to punch the nurse squeezing the saline in. I swear on my life I am not exaggerating when I say I couldn't walk for about 10 minutes afterwords. I thought I was going to have to call the nurses back in to help me.

    For non-IF procedures, I'd say the prep for a colonoscopy is the worst procedure I've ever had overall! Starving yourself for an entire day then drinking ungodly amounts of miralax mixed with yellow gatorade and dulcolax makes you so sick you need a seatbelt for your toilet. I shutter just thinking about it!

    ************ Signature/Ticker Warning ************
    Me (32) DH (36) - Finding our way to baby #1
    Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
    DH: Severe MFI

    12/2/11 - IUI #1- BFN 
    8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

    My ovaries are just for decoration

    12/6/12 - Adopted five embryos that had been frozen for over ten years!
    2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
    2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
    3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

    6/5/13 - Adopted four new embryos that had been frozen for seven years!
     
    9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
    9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
    9/29/13 - m/c @ 5w1d. :(

    11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
    11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
    Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
    6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

    Snowflake baby is a girl! 
    Our beautiful Snowflake girl arrived on July 22, 2014!   
    My embryo adoption blog: Wishing on a Snowflake
     
        image      image 
  • I feel your pain.. I've had 2 endometrial biopsies.  It hurts like a SOAB. I did take a valium before my last one and it helped somewhat.  It is by far my least favorite procedure.  I have heard that if you have one close to a cycle it can help in implantation.  
    Me 35, DH 36
    TTC summer 2008
    Diagnose me. DOR, DH perfect
    IUI # 1 6/2010, BFN
    IUI # 2 8/2010, BFN
    IVF # 1 10/2010 Canceled poor response
    IVF 1.2 12/2010 BFP! mc 6 weeks 2 days
    Mental health break for 10 months
    IVF # 2 10/2011 BFN
    IVF # 3 5/2012 BFP! 10 eggs retrieved (best ever)
    7 fertilized transferred 3
    Beta #1 14dpo - 72, Beta #2 17dpo 145 Beta 3 20dpo 521
    First u/s June 15 saw HB 126 bpm missed m/c 7/5/12 10 weeks D&C 7/6/12
    IVF#4 ER 9/30 ET 10/3 Beta 10/16 BFFN. IVF #5 final with o/e. ER 1/21 only 1 retrieved, hoping my lonestar is the one. Beta #1 2/6/13 = 209.... please let this be it! Keep growing lonestar! Beta #2 2/8/13 - 586! , Beta #3 2/10/13 = 1898. First u/s perfect little heart beat at 116 bpm. Measure 6 weeks 1 day. EDD 10/14/13
    3/4/13 measuring right on track beautiful heartbeat 171 bpm, graduated from RE to OB... bittersweet.
    PAIF/SAIF always welcome! Its a girl! 

    Maggie Grace is here!  10/5/13... 8lbs 6 ounces of pure joy!

    TTC#2  No birth control since DD was born.  Getting ready to jump back in the saddle.  Weaning this month. RE
    appt scheduled 5/8.   Here we go again!

    IFV# 6.  10/27  6 retrieved 4 mature 3 fertilized.  2 made it to 3dt 10/30. 1"very pretty 8 cell" and 1 6 cell.  Beta
    11/13.   Please stick embies!!!!  We love you so much already! 11/12/14  POAS, BFP... beta tomorrow!
    11/13 beta #1  924!!!  2nd bet 11/15 1906, one more on 11/17 3rd & final beta 3430.  First u/s 12/5, 7w4d, 2 heartbeats,
    both measuring right on track....2nd u/s... all is well... both beans measuring right on track... released from RE... first
    appointment with MFM 1/5.  Looks like this is really happening!

    image




  • imageJulie21613:
    I feel your pain.. I've had 2 endometrial biopsies.  It hurts like a SOAB. I did take a valium before my last one and it helped somewhat.  It is by far my least favorite procedure.  I have heard that if you have one close to a cycle it can help in implantation.  

    I took 750mg of Tylenol before this one. Not sure if it helped. Placebo effect mainly.

    The last time I had it done I did have a PG - but with our history I'm not sure if it made any difference or not. Huh?

    BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08
    TTC #1 since 1/10
    DX: Unexplained/??? MFI issues

    Our lil' lost sparks:
    5w3d loss 7/30/10 - EDD March 2011
    8w loss 4/15/11 - EDD November 2011
    8w3d loss 8/2/12 - EDD March 2013
    4w c/p loss 10/29/12 - EDD July 2013

    Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
    RPL testing all normal, Karyotyping normal

    Moving on to IVF.

    IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

    Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
    IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
    FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
    Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14

    After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14
    We are so in love with her.

    "I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

    Everybody is welcome!!!
  • Ugh, that sounds terrible!!!  So glad that you've got it done and over with -- hoping that you get great results and get them quickly.

    QOTD:  HSG was definitely the worst for me.  Like DP, I got the "period like cramping" warning -- but, I've never had cramps that felt that terrible (and my tubes were wide open/clear).  The advil or motrin or whatever they had me take beforehand didn't seem to do a thing.  To add to the fun, I had ridiculous bleeding + passing of biggest clots ever (for me) through that night. (it all made giving myself my own PIO injections seem like a piece of cake in this crazy process)

    TTC since honeymoon in 9/2010
    Me: 39, Dx DOR (FSH = 10.5, AMH = 0.43, best AFC = 10), AMA
    MH: 37, Dx Obstructive Azoospermia, multiple successful sperm retrieval procedures

    1/2012: IVF/ICSI #1 Antagonist = cancelled d/t poor response to max stims
    2/2012: IVF/ICSI #2 MDLF (4R, 4M, 1F) = BFP, saw heartbeat, missed m/c 9w0d, D&E
    8/2012: IVF/ICSI #3 EPP/MDLF (7R, 2M, 1F) = BFN

    12/2012: (New RE) Operative hysteroscopy to remove scar tissue

    1/2013: IVF/ICSI #4 Low-dose stim/Antagonist (AFC=6); ER=1/26 (5R-couldn't access rt ovary, 5M, 4F), ET=1/29 (trans 3) = BFP!; 2/11 beta#1(13dp3dt)=2127, 2/13=3367; twin girls due 10/19/13

    PAIF/SAIF very welcome!

    <a href="http://www.thebump.com/?utm_source=ticker&utm_medium=HTML&utm_campaign=tickers" title="Pregnancy"><img src="http://global.thebump.com/tickers/tt16bf7d.aspx" alt=" BabyFruit Ticker" border="0"  /></a>
  • You're a brave soul!  Hope you get the result back soon.  You are on your way, toots!
    Baby girl Lila born 2013.
    Baby boy Henry born 2015.
    Expecting our capstone baby (boy) early March 2018.
This discussion has been closed.
Choose Another Board
Search Boards
"
"