Infertility Veterans

Anyone with adenomyosis?

As part of my workup for my upcoming DE cycle the CA clinic wanted a current SIS (my last was seven months ago) and it showed adenomyosis.  I am fairly concerned because, according to my RE, the area affected is a critical implantation area and the medical studies I have read so far are less than positive regarding IVF outcome (some siting up to a 50% lower ongoing pregnancy rate). 

 

Oh and of course, the worst thing for this is estrogen, of which I will be pumping copious amounts of into my body for the DE cycle.  Why can?t things ever go smoothly in this IF journey?  You just get your head around one thing and you are given something else to deal with.



***SIGNATURE WARNING***


TTC #1

Me 42, DH 47

Dx = AMA/DOR, MFI

IVF/ICSI #1 = BFN

IVF/ICSI #2 = BFP; early loss

IVF/ICSI #3 (DE) = BFP; early loss

FET = BFN

IVF/ICSI #4 (DE w/ CCS) = BFP

Beta #1 @ 10dp6dt = 265; Beta #2 @ 14dp6dt = 1251. 

1st U/S @ 6w2d showed one perfect little heartbeat! 

2nd U/S @ 7w2d. HB 132 & everything measuring on track.

Our beautiful little girl arrived January 2015!


Re: Anyone with adenomyosis?

  • Oh no.  No advice yet on adenomyosis, but I have a WTF appointment tomorrow after my DE IVF BFN.  Does your RE think you shouldn't progress?  Are there treatments for it?  

    Me: now over 40, careerwoman; DH: 34 love of my life
    Blood work, anatomy and his SA = in fine shape say drs
    Our journey so far:
    7/09: BFP m/c 6w s/e/p, 2 rounds methotrexate
    4/10 BFP m/c 6w D&C..it was a boy :(
    6/10-2/11 TTC naturally, BFNs
    3/11: Clomid cycle, BFN
    4/11-9/11 TTC naturally, BFNs
    10/11 IUI #1 BFN
    Have to breathe over next few months.
    Feb 2012: IVF #1, max stims, only 3 retrieved, all fertilized, only 1 transferred on Day 3. BFN.
    RE says move to DE. DE it is.
    DE IVF #1 - 10/29: 12 eggs retrieved, 10 fert. 11/2: Day5 transfer 2 'perfect' blasts. 4 blasts on ice. 11/11: Beta #1 at 9dp5dt = 72.7 11/13: Beta #2 at 11dp5dt: 30.3 c/p :( WTF appt 11/27: RE a little dumbfounded. Checking Thyroid panel again, Hysterogram as well; FET most likely in Jan. '13.have reconsidered a parallel path of adoption.
    PAIF&SAIF always welcome
  • I do not have advice, but wanted to offer hugs. I can see why you are feeling especially frustrated with the process today. Hang in there and good luck moving forward.

    Countless BFN(s)
    Moving to IVF

    IVF1 (ICSI): Long Lupron
    6R. 3F. 3DT. 8Cell 1Grade 2Embies. 1Frostie.
    Beta 1/22: 14 Beta 1/24: 24 Beta 1/26: 28
    Round One Result: Chemical Pregnancy

    Pressing Forward

    IVF2 (ICSI/AH/ACU): Microdose Lupron Flare
    13R. 11F. 5DT. 2TFR'ed. 1Frostie.
    Round Two Result 4/30: Harsh BFN

    FET. 2TFR'ed.
    Round Three Result 6/25: BFN
    Where do we go from here?

    Moving forward with CCRM in 2013
    ODWU revealed blocked tube(s). Lap 2/15.
    Bilateral Tubal Ligation. Stage IV Endo.
    Finally some (tough) answers.


    IVF3 (ICSI/CCS): Antagonist with EPP
    13R. We have 3 CCS Normal Embryos!


    Lupron Depot: May 2013 to August 2013
    Long awaited FET on 9/3. 2TFR'ed.
    BFP on FRER 5dp5dt: IN SHOCK!
    Beta1 9/10: 152.7! Beta2 9/12: 378! Beta3 9/14: 1224! 

    1st ultrasound 10/1: TWO beautiful heartbeats!  Overjoyed!

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  • imagerockpaperlove:
    I do not have advice, but wanted to offer hugs. I can see why you are feeling especially frustrated with the process today. Hang in there and good luck moving forward.

    This! I'm sorry your cycle has gotten off to a bumpy start. FX the MRI gives better results.


    ***signature & ticker warning***


    Me: 30 ~ Stage IV Endo ~ AMH .38 ~ AFC 8
    AMH .97 as of 4/2012! ~ AMH 1.63 as of 4/2013!?!

    Him: 29 ~ perfect swimmers

    Laparotomy w/partial oophorectomy 8/2009 to remove cysts/endo.
    Stopped BCP 4/2010.
    Multiple clomid rounds from 11/2010 to 6/2011. ~ All BFN
    IUI w/clomid 7/2011. IUI w/clomid & injectables 11/2011 & 1/2012. ~ All BFN

    IVF:EPP 5/2012 ~ (4R, 3M, 2F w/ICSI). Both embryos txfrd. ~ BFN
    BCP to manage endo from 10/2012 to 12/2012.
    FET w/donor embryos #1: 10/2013 Cancelled
    FET w/donor embryos #1.2: 11/2013
    ~ ET of 2 beautiful blasts on 11/27.
    Beta 1: 503(12dp5dt) Beta 2: 1035(14dpt) Beta 3: 3001(16dpt)
    Beta 4: 8503(19dpt)
    Twins with an EDD of 8/15/14! Team Purple
    G&B born 6/30/14 at 33w3d via emergency c/s.


    If you're wondering about my avatar...it's a fried pickle chip shaped like a fetus!


    image

    image
  • Gosh, I have never heard of this condition. I am so sorry that you have encountered another road block. What does your doc have to say about this? 

    Doesn't it sometimes feel like you are in a sh!t storm without an umbrella.

     Sending you lots of strength. I wish I had something wise and helpful to say, but all I have is love. 

    imageimage

    TTC#1 since October 2010

    "The jump is so frightening between where I am and where I want to be...because of all I may become I will close my eyes and leap." Mary Anne Radmacher

    Me:35, 5 major abdominal surgeries for Ulcerative colitis, failed j pouch, perm. Ileostomy DX-DOR & Tubal abnormalities/Extensive Adhesions from earlier surgeries.latest fsh -26 :(

    IVF 1- March 2012 Antagonist Protocol; BCP until March 3; AFC this cycle is 10 (Hooray); Start stims on March 9; ER on March 19- 2R; 2T (1 perfect 8 cell, 1 scrappy 3 cell); tubal infection from ER-hospitalized. Doomed! BFN

    Essure Procedure to treat bilateral hydrosalpinx; June 2012, wait 3 months for confirmation test.

    IVF2 (Egg Banking)-letrozole/antagonist cycle; June/July 2012 225iu merional + cetrotide; slow responder, Ovulated before ER. Unbelievable. Canceled remaining cycles with my eggs

    DE IVF in Brno, Czech. Approx. ET on Oct 6 CANCELLED-Essure didn't close both tubes-test again in 3 months

    IVF3-DE IVF ET on Dec 9, 2012 (decided to roll the dice no matter what!)

    2 perfect HB transferred; 8dp5dt beta:36; 10dp5dt beta 15; chemical pregnancy.

    Turning our hearts toward adoption

    DH:36, SA-perfect

    Married since July 11, 2009

    Fur baby Cairn Terrier

    SAIF/PAIF Welcome

  • imageSuzanneJesse:
    Oh no.  No advice yet on adenomyosis, but I have a WTF appointment tomorrow after my DE IVF BFN.  Does your RE think you shouldn't progress?  Are there treatments for it?  

    I am so sorry to hear about your c/p :(  (((Hugs)))


    As apparently adenomyosis just keeps getting worse, my RE definitely wants me to move forward.  It is just the realization that there is now something else working against me besides my eggs.  


    They told me that there are no real treatments but Lupron can help suppress it a bit temporarily.  Apparently it is most common in women of AMA.


    Good luck with your WTF today!

     


    ***SIGNATURE WARNING***


    TTC #1

    Me 42, DH 47

    Dx = AMA/DOR, MFI

    IVF/ICSI #1 = BFN

    IVF/ICSI #2 = BFP; early loss

    IVF/ICSI #3 (DE) = BFP; early loss

    FET = BFN

    IVF/ICSI #4 (DE w/ CCS) = BFP

    Beta #1 @ 10dp6dt = 265; Beta #2 @ 14dp6dt = 1251. 

    1st U/S @ 6w2d showed one perfect little heartbeat! 

    2nd U/S @ 7w2d. HB 132 & everything measuring on track.

    Our beautiful little girl arrived January 2015!


  • imageglueck:

    Doesn't it sometimes feel like you are in a sh!t storm without an umbrella.

    Love this!  Thank you for bringing a smile to my face!!! 


    ***SIGNATURE WARNING***


    TTC #1

    Me 42, DH 47

    Dx = AMA/DOR, MFI

    IVF/ICSI #1 = BFN

    IVF/ICSI #2 = BFP; early loss

    IVF/ICSI #3 (DE) = BFP; early loss

    FET = BFN

    IVF/ICSI #4 (DE w/ CCS) = BFP

    Beta #1 @ 10dp6dt = 265; Beta #2 @ 14dp6dt = 1251. 

    1st U/S @ 6w2d showed one perfect little heartbeat! 

    2nd U/S @ 7w2d. HB 132 & everything measuring on track.

    Our beautiful little girl arrived January 2015!


  • imageSophistikitty:
    imageglueck:

    Doesn't it sometimes feel like you are in a sh!t storm without an umbrella.

    Love this!  Thank you for bringing a smile to my face!!! 

    Oh, KITTY! XOXOXOXO 

    imageimage

    TTC#1 since October 2010

    "The jump is so frightening between where I am and where I want to be...because of all I may become I will close my eyes and leap." Mary Anne Radmacher

    Me:35, 5 major abdominal surgeries for Ulcerative colitis, failed j pouch, perm. Ileostomy DX-DOR & Tubal abnormalities/Extensive Adhesions from earlier surgeries.latest fsh -26 :(

    IVF 1- March 2012 Antagonist Protocol; BCP until March 3; AFC this cycle is 10 (Hooray); Start stims on March 9; ER on March 19- 2R; 2T (1 perfect 8 cell, 1 scrappy 3 cell); tubal infection from ER-hospitalized. Doomed! BFN

    Essure Procedure to treat bilateral hydrosalpinx; June 2012, wait 3 months for confirmation test.

    IVF2 (Egg Banking)-letrozole/antagonist cycle; June/July 2012 225iu merional + cetrotide; slow responder, Ovulated before ER. Unbelievable. Canceled remaining cycles with my eggs

    DE IVF in Brno, Czech. Approx. ET on Oct 6 CANCELLED-Essure didn't close both tubes-test again in 3 months

    IVF3-DE IVF ET on Dec 9, 2012 (decided to roll the dice no matter what!)

    2 perfect HB transferred; 8dp5dt beta:36; 10dp5dt beta 15; chemical pregnancy.

    Turning our hearts toward adoption

    DH:36, SA-perfect

    Married since July 11, 2009

    Fur baby Cairn Terrier

    SAIF/PAIF Welcome

  • imageSophistikitty:

    imageSuzanneJesse:
    Oh no.  No advice yet on adenomyosis, but I have a WTF appointment tomorrow after my DE IVF BFN.  Does your RE think you shouldn't progress?  Are there treatments for it?  

    I am so sorry to hear about your c/p :(  (((Hugs)))


    As apparently adenomyosis just keeps getting worse, my RE definitely wants me to move forward.  It is just the realization that there is now something else working against me besides my eggs.  


    They told me that there are no real treatments but Lupron can help suppress it a bit temporarily.  Apparently it is most common in women of AMA.


    Good luck with your WTF today!

     

    HI Kitty - had my WTF today and I asked if there is anyway I could have undx endo and my RE was like NO, that wouldn't have anything to do with it anyway.  yes, I read that endo (or extreme forms) could impede implantation.  Frustrating.  he's ordered a hysterogram, but won't do a uterine biopsy.  We are going to run the full thyroid panel again and I'm just going to insist on going on synthroid.  

    So we're shooting for a FET cycle in January - you are too correct? I'm rooting for you!  

     


    Me: now over 40, careerwoman; DH: 34 love of my life
    Blood work, anatomy and his SA = in fine shape say drs
    Our journey so far:
    7/09: BFP m/c 6w s/e/p, 2 rounds methotrexate
    4/10 BFP m/c 6w D&C..it was a boy :(
    6/10-2/11 TTC naturally, BFNs
    3/11: Clomid cycle, BFN
    4/11-9/11 TTC naturally, BFNs
    10/11 IUI #1 BFN
    Have to breathe over next few months.
    Feb 2012: IVF #1, max stims, only 3 retrieved, all fertilized, only 1 transferred on Day 3. BFN.
    RE says move to DE. DE it is.
    DE IVF #1 - 10/29: 12 eggs retrieved, 10 fert. 11/2: Day5 transfer 2 'perfect' blasts. 4 blasts on ice. 11/11: Beta #1 at 9dp5dt = 72.7 11/13: Beta #2 at 11dp5dt: 30.3 c/p :( WTF appt 11/27: RE a little dumbfounded. Checking Thyroid panel again, Hysterogram as well; FET most likely in Jan. '13.have reconsidered a parallel path of adoption.
    PAIF&SAIF always welcome
  • Hey, I have adenomyosis too. RE put me on Lupron Depot for several months before my DE cycles. I don't know if it had anything to do with my losses, but it was hard to find out that my eggs aren't the only problem. Unfortunately because it grows inside the wall of the uterus there really is no way to remove it. It sucks. But, it doesn't necessarily mean you can't have a successful pregnancy .
    Dx: High FSH, stage IV endo, homozygous C677T MTHFR and PAI-1
    Early loss 10/08
    Lap 1/09
    IVF #1 "natural IVF" - 1 egg retrieved, missed m/c
    Tried several mini-stim cycles with no response
    Switched clinics - dx'd as carrier for Fragile X
    IVF #2 MDL protocol Jan/Feb converted to IUI, BFN
    IVF #2 take 2: Antagonist, one embie, BFN
    IVF #3: Antagonist, no fertilization
    One last ditch effort at OE IVF (antagonist with Clomid) cancelled
    DE cycle #1 Jan/Feb 2011, BFP, ectopic
    DE cycle #2 June/July 2011 - BFP
    10/28/11 Baby girl lost at 17 weeks due to pre-term labor. We love and miss you.
    DE cycle #3 June/July 2012 - BFP, twins, both heartbeats stopped, D&C
    2 frosties but don't know what's next
    FET Dec 2012: BFP! Praying this one sticks for the long haul!
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