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Progesterone Shots ?

JewelsW1980JewelsW1980 member
in Infertility
Happy Thanksgiving ladies!!! Enjoy your time with your loved ones!

I need advice on how to make the aftermath of these shots less painful.

I'm on day 4 of the progesterone shots, the actual shot doesn't hurt at all, nor does the medication when injected, but several hours later my muscle where the liquid was pushed kind of knots up and eventually bruises. We rotate sides, rub it for several minutes afterward and I hot compress it and it's still bruising.

Anyone have a suggestion I haven't thought of? TIA!

Me- 32, DH- 32- TTC for 4 Years
IUIs 1-6 BFN
IVF #1= BFP- M/C
FET- Beta#1: 69, #2: 482, #3: 1088, #4: 28,318, Ultrasound- 1 beautiful heartbeat
It's a boy!

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Re: Progesterone Shots ?

  • CNYBride05CNYBride05 member
    Ice first, then shot. Then massage for a few minutes, get up and walk around and then put a heating pad on your butt for a few minutes.

    GL!!
    Natural m/c Oct. 2005

    Dx: balanced translocation and LPD

    TTC since Oct 2011

    BPF 02/19/12, EDD 10/31/12, natural m/c 02/28/12 (4w6d)

    IVF (BCPs starting 10/30/12, ER 11/18/12, 5dt of 1 beautiful, healthy embryo 11/23/12)
    BFP 12/02/12, u/s @ 6w,5d showed 2 HBs! Identical twins!!
    Bed rest from 21w-35w due to short cervix, hospital bed rest from 23w-32w due to PTL
    Our rainbows were born 07/19/13 (36w, 5d)

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  • ShelleyBQShelleyBQ member

    **sig warning**

     

    I wouldn't ice at all- if the muscle is cold (before or after) it can crystallize the progesterone.  I am using a heating pad before and after, and also massaging it.  Hold the vial in your hand for a few minutes to warm it up, also, before you draw up the liquid.  My last suggestion would be to make sure you check with your doctor about where you are injecting.  My sister (a nurse) drew my targets the first time, and it hurt a lot after the injections in those places.  My RE's nurse did it the second time, and they are somehow higher up and it doesn't leave as much lasting pain. Good luck!

      image

    TTC starting November 2010  HSG clear, DH SA #1- Slightly low count & motility SA#2-normal
    Lap&Dye/Hysterscopy Feb 2012: Endo stage 2
    April - June 2012: Femera 5 mg & 3 IUIs = All BFN    July/August 2012: IVF #1 = C/P
    September/October 2012: IVF #2 BFP! Beta 1= 223 Beta 2 = 480 Beta 3 = 11,440
    My beautiful daughter was born June 21, 2013
    TTC #2 naturally, no luck
    IVF #3 April 2015: BFN
    IVF #4 July 2015: BFP! Beta 1 9dp5dt = 409, Beta 2 13dp5dt = 1743


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  • precious72381precious72381 member
    Nope, but I am so sore too. I was excited after the first shot thinking how little it hurt compared to the shots in my stomach. I have only done two so far, one on each side, and my back is so sore. I will try the ice first today. GL!!! Hope you feel better!

    I'm 33 DH is 36 
    Married 6/27/2009 Together since 10/22/2005
    TTC since 8/2010 (off BCP since 8/2009)     Unexplained Infertility
    8/2011, 1/2012, 3/2012 IUI #1-3 BFN 
    6/2012 IVF#1 BFN, 8/2012 IVF#2 FET BFN, 11/2012 IVF#3 BFP
    12/10/2012 U/S #1 6w4d - heartbeat  EDD 8/1/13 
    12/26/2012 U/S #2 8w6d - No more heartbeat, MMC; D&C; Chromosome testing normal; male :( RPL testing normal 
    4/3/2013 DX Asherman's Syndrome caused by D&C, hysteroscopy done
    June 2013 IVF #4 planned 
    5/12/2013 SURPRISE BFP! Natural cycle 
    7/11/2013 Panorama results Normal!!! Team Pink, partial previa moved up in 2nd tri9/5/13 (19w) AS scan shows short cervix, 2.5 cm 9/19 (21w)  Cervix is worse 1.87cm, bed rest 10/26 & 10/27 steroid shots 12/19 (35w) DX: SGA Baby went from 57% percentile to 18th percentile in 6 weeks. Weekly BPP and NST until she is here. 1/17/18 Growth scan puts Abby below 10th percent in size, low amniotic fluid, and less movement. Time to induce!
    1/18/14 2:11am Abigial Morgan is here! 5lbs 14oz and 18 inches of pure cuteness!!!

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  • precious72381precious72381 member
    Okay, no ice! Will try higher up too. Thanks for that. Should have read what others wrote first!

    I'm 33 DH is 36 
    Married 6/27/2009 Together since 10/22/2005
    TTC since 8/2010 (off BCP since 8/2009)     Unexplained Infertility
    8/2011, 1/2012, 3/2012 IUI #1-3 BFN 
    6/2012 IVF#1 BFN, 8/2012 IVF#2 FET BFN, 11/2012 IVF#3 BFP
    12/10/2012 U/S #1 6w4d - heartbeat  EDD 8/1/13 
    12/26/2012 U/S #2 8w6d - No more heartbeat, MMC; D&C; Chromosome testing normal; male :( RPL testing normal 
    4/3/2013 DX Asherman's Syndrome caused by D&C, hysteroscopy done
    June 2013 IVF #4 planned 
    5/12/2013 SURPRISE BFP! Natural cycle 
    7/11/2013 Panorama results Normal!!! Team Pink, partial previa moved up in 2nd tri9/5/13 (19w) AS scan shows short cervix, 2.5 cm 9/19 (21w)  Cervix is worse 1.87cm, bed rest 10/26 & 10/27 steroid shots 12/19 (35w) DX: SGA Baby went from 57% percentile to 18th percentile in 6 weeks. Weekly BPP and NST until she is here. 1/17/18 Growth scan puts Abby below 10th percent in size, low amniotic fluid, and less movement. Time to induce!
    1/18/14 2:11am Abigial Morgan is here! 5lbs 14oz and 18 inches of pure cuteness!!!

    Image and video hosting by TinyPicImage and video hosting by TinyPicImage and video hosting by TinyPicImage and video hosting by TinyPic

    Baby Birthday Ticker Ticker
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  • brooklynesquebrooklynesque member

    The progesterone video here shows pretty good placement, I think.  It's higher than you'd think when you think "buttock," LOL.

    https://www.freedommedteach.com/player/Videos.aspx 

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  • rrdiva1rrdiva1 member

    I see they suggested the same thing I was going to say, no ice but maybe aim a little higher and rub the ish out of it right after. I had no knots and I did it for like 2 weeks last cycle. I was a bleeder though that tend to be my issue more so than anything.

    GL at transfer!!!! <3

    Married BF 6/29/2002/
    TTC Since Aug 2011/
    ME:34 all clear/DH:41 DX Severe MFI/
    IVF w/ICSI OCT 2012 Stims started 10/8/ER 10/19/12/ET 10/24/Beta#1 11/2=BFN (beta was 1.2)

    IVF 2.0-Baseline 11/7/12 beta 0/All Clear
    Stim start 11/7/12//ER 11/19 11M//10F
    ET 2 embies 11/24//Beta#1 28 Beta #2 23 Beta#3 29
    stop meds Beta#4 37/C/P 5W5D EDD:8/12/13/IVF#3 in Jan

    Ivf 3-frozen 3 poor 3day/fet=bfn

    Ivf#4 New dr. New protocol=beta1 197 beta#2 677 beta#3 1557
     u/s 8/13 =TWINS 2 strong hb
    Due Date 4/4/14

    image

    My Chart//>
    image
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  • megs3084megs3084 member
    I'm not on PIO, but my friends that have had it said if you lean over on something & take the weight off the leg you're injecting, it helps too.  Good Luck!!
    "Everything will be alright in the end. So if it's not alright, it is not yet the end."
    Me:29 DH:29  TTC since 1/11 Dx: unexplained IF/early DOR/immune issues 
    Feb'12- July'12-testing(all clear minus slight arcuate ute), 3 IUI with clomid all BFN
    8/30IVF#1 Antagonist protocol- ER 9/11-8R, 7M, 5F. 
    ET 9/14 2 embies transferred. 1 10cell Grade 4, 1 8cell Grade 4. No frosties. BFN
    IVF#2 Antagonist protocol plus baby aspirin- ER 12/5-16R, 12M, 8F!
    ET 12/10 5dt! 1 fully expanded blast & 1 early blast. No frosties. BFN
    3/13 hysteroscopy & polypectomy, Consulted w Dr. Kwak-Kim.  
    DX: High NK cells, cytokines, DHEAs& PAI1;  hypothyroid, +APA, restricted bloodflow
    7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle
    (plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim)
    ER 7/19 14R, 11M, 9F(4 natural fert, 5 with ICSI)
    ET 5dt 7/24 2 fully expanded blasts.  SURPRISE 3 FROSTIES!!!
    Beta #1 8/2 335!!!! Beta #2 829!!!  1st u/s 8/14 showed TWINS!!!!!
    11/11: TEAM PURPLE!!!!!
    3/21/14-L&W born at 37w via csection
    Here Comes the Sun Blog
    PAIF/SAIF welcome!
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  • Mayzie15Mayzie15 member
    No ice. I warmed the PIO between by hands for a few minutes. Agree with others make sure your injecting it in the right spot. After injection I massaged the area and sat on a heating pad minimum of 15 minutes. Didn't have soreness or bruising. Good luck!!!

    Me 38 MH 41 - TTC since June 2010 - dx with Severe MFI. Straight to IVF with ICSI. IVF #1 - ER 06/13/12 - 9 Eggs Retrieved - 4 ICSI'd - only 2 fert. 06/15/12 - 2DT - 3 cell & 6 cell with fragmentation. Beta 06/29/12 - IVF #1 = BFN. 07/20/12 - WTF Appt -Told by our RE to quit IVF. Second Opinion from RE is good. IVF#2 - November 2012. Estradiol Pills Started 11/6. Stims start 11/16. ER 11/26 - 7 eggs retrieved - all mature. 4 fertilized with ICSI. ET 11/29 Transferred 3 embryos. Beta is 12/10. 1st Beta 81 2nd Beta 160 and 3rd beta 360!!! First U/S 12/21/12 - We saw one beautiful gest. sac. 2nd U/S is 01/04/2013 - H/B 183 02/05/13 - NT Scan - everything looks good and IT'S A BOY!  Aiden was born 08/20/2013.

    IVF #2 is in progress.  ER was 05/12/14 - 11 eggs retrieved, 8 fertilized with ICSI.  ET was 05/15/14 - we transferred 3 embryos as we did on the cycle my son was conceived.  We were able to freeze 3 embryos. Beta is scheduled for 05/26/14.  1st beta - 111.  2nd beta - 159 didn't double :( 3rd beta Friday 5/30) - not a lot of hope left. Beta # 3 is 247 - probably ectopic.  Beta # 4 is 813 - possibly vanishing multiple sydrome?  06/05/14 - 5w4days - first U/S - we see a gestational sac and yolk - still have hope!  06/17/14 - 7w1day - U/S and saw and heard the heartbeat - Finally!  06/27/14 - 8w4days - Baby and heartbeat look and sound great :)  EDD 02/01/14 and It's a boy!


     "Everything will be okay in the end. If it's not okay, it's not the end."


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  • CNYBride05CNYBride05 member
    Everyone seems to have their own way of doing things :-)  I will add that I lie down on the bed.  While DH is icing the area he's going to inject, I hold the syringe in my hand to warm up the PIO.  I haven't had any issues with bruising and minimal soreness.
    Natural m/c Oct. 2005

    Dx: balanced translocation and LPD

    TTC since Oct 2011

    BPF 02/19/12, EDD 10/31/12, natural m/c 02/28/12 (4w6d)

    IVF (BCPs starting 10/30/12, ER 11/18/12, 5dt of 1 beautiful, healthy embryo 11/23/12)
    BFP 12/02/12, u/s @ 6w,5d showed 2 HBs! Identical twins!!
    Bed rest from 21w-35w due to short cervix, hospital bed rest from 23w-32w due to PTL
    Our rainbows were born 07/19/13 (36w, 5d)

    Baby Birthday Ticker Ticker
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  • JewelsW1980JewelsW1980 member
    Thanks ladies! We haven't done the warm the med in the hand thing so we'll give that a go! I'm assuming its just my bodies reaction to this stuff. Bah

    Me- 32, DH- 32- TTC for 4 Years
    IUIs 1-6 BFN
    IVF #1= BFP- M/C
    FET- Beta#1: 69, #2: 482, #3: 1088, #4: 28,318, Ultrasound- 1 beautiful heartbeat
    It's a boy!

     BabyFruit Ticker

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