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Another FET question - natural FET?

may2806may2806 member
in Infertility Veterans

Sorry if my Qs are getting tiresome! I'm just trying to understand everything my RE and RI want to do. RI wants to use Letrozole during FET, RE says no. It does seem counterintuitive, but there was a study that showed it helps with lining and implantation in women who have endo. I think it would be similar to doing a natural FET, in which you would actually ovulate. In my case I doubt anything would make me ovulate, but I'm wondering, just for argument's sake, how a natural FET works as opposed to a medicated one.

Do you take any estrogen/progesterone for a natural FET? What would happen if I took Letrozole and but didn't actually ovulate - would it affect my hormones or the dosages of estrogen/progesterone I would need? 

Trying to figure out if there's any argument I could use with the RE. Thanks! 


Dx: High FSH, stage IV endo, homozygous C677T MTHFR and PAI-1
Early loss 10/08
Lap 1/09
IVF #1 "natural IVF" - 1 egg retrieved, missed m/c
Tried several mini-stim cycles with no response
Switched clinics - dx'd as carrier for Fragile X
IVF #2 MDL protocol Jan/Feb converted to IUI, BFN
IVF #2 take 2: Antagonist, one embie, BFN
IVF #3: Antagonist, no fertilization
One last ditch effort at OE IVF (antagonist with Clomid) cancelled
DE cycle #1 Jan/Feb 2011, BFP, ectopic
DE cycle #2 June/July 2011 - BFP
10/28/11 Baby girl lost at 17 weeks due to pre-term labor. We love and miss you.
DE cycle #3 June/July 2012 - BFP, twins, both heartbeats stopped, D&C
2 frosties but don't know what's next
FET Dec 2012: BFP! Praying this one sticks for the long haul!
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Re: Another FET question - natural FET?

  • Edwina.McDunnoughEdwina.McDunnough

    From what I understand, unmedicated would be progesterone only, if that. Y ovulate on your own so if you don't ovulate regularly its not a great option. Your RE tracks your surge and ovulation through monitoring and ET is scheduled. Lots of apps.

    If you were on e2 and p4 AND letrozole, and no follies developed and you did not surge, then all your lining etc would be controlled by your meds. That is my guess.

    +++
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  • mdluv21mdluv21

    Natural FET don't use suppression or estrogen drugs.  They just monitor when you are going to ovulate via b/w and u/s.

     

    I don't ovulate regulary and my RE doesn't do them so it wasn't an option for me.

    TTC since 07/2009
    Me: PCOS, Blood/Immune Issues DH: Low all 3
    Jun.- Sep. 2010 IUI#1-#3 = BFN
    Oct. 2010 = IVF #1 = B/G Twins (passed away Feb. 2011)
    May 2011 = Myomectomy and trans-abdominal cerclage (TAC)
    Sep. 2011 = Surprise BFP = C/P
    Feb. 2012 = sFET #1 = BFN
    Feb.2012 = Hail Mary IUI #4 = BFN
    April/May 2012 = FET #2 w/our last two embies = BFP (Please let this be it!)
    Beta #1 8dp5/6dt = 234 Beta #2 10dp5/6dt = 695 Beta #3 12dp5/6dt = 1796 Beta #4 17dp5/6dt = 17,888 U/S #1 May 17, 2012 = Twins
    Baby B's heart stop beating at 9 weeks 5 days
    Our little miracle baby is a boy. :)

    Baby Boy Owen and Baby Girl Avery were born too early on Feb. 13, 2011 due to a pedunculated fibroid, incompetent cervix and suspected placental abruption.
    Lilypie Angel and Memorial tickers

    "What the heart has once owned and had, it shall never lose." - Henry Ward Beecher
    SAIF/PAIF Welcome
    Lots of love and luck to my PAIF/3T/IF Veteran ladies, especially my dear friend Zookie. Congrats to Papps, Teach84 and Starbuck on their little ones.
    Report Reply
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  • may2806may2806 member
    I'm not saying that natural would be an option for me; I'm just wondering how that would compare with using letrozole during a FET in order to try to convince the RE of the RI's plan.
    Dx: High FSH, stage IV endo, homozygous C677T MTHFR and PAI-1
    Early loss 10/08
    Lap 1/09
    IVF #1 "natural IVF" - 1 egg retrieved, missed m/c
    Tried several mini-stim cycles with no response
    Switched clinics - dx'd as carrier for Fragile X
    IVF #2 MDL protocol Jan/Feb converted to IUI, BFN
    IVF #2 take 2: Antagonist, one embie, BFN
    IVF #3: Antagonist, no fertilization
    One last ditch effort at OE IVF (antagonist with Clomid) cancelled
    DE cycle #1 Jan/Feb 2011, BFP, ectopic
    DE cycle #2 June/July 2011 - BFP
    10/28/11 Baby girl lost at 17 weeks due to pre-term labor. We love and miss you.
    DE cycle #3 June/July 2012 - BFP, twins, both heartbeats stopped, D&C
    2 frosties but don't know what's next
    FET Dec 2012: BFP! Praying this one sticks for the long haul!
    Report Reply
  • mdluv21mdluv21
    It might work!  A girl in my resolve group did an IUI with a FET since she was doing a natural FET and actually releasing egg too.  She did get pregnant.
    TTC since 07/2009
    Me: PCOS, Blood/Immune Issues DH: Low all 3
    Jun.- Sep. 2010 IUI#1-#3 = BFN
    Oct. 2010 = IVF #1 = B/G Twins (passed away Feb. 2011)
    May 2011 = Myomectomy and trans-abdominal cerclage (TAC)
    Sep. 2011 = Surprise BFP = C/P
    Feb. 2012 = sFET #1 = BFN
    Feb.2012 = Hail Mary IUI #4 = BFN
    April/May 2012 = FET #2 w/our last two embies = BFP (Please let this be it!)
    Beta #1 8dp5/6dt = 234 Beta #2 10dp5/6dt = 695 Beta #3 12dp5/6dt = 1796 Beta #4 17dp5/6dt = 17,888 U/S #1 May 17, 2012 = Twins
    Baby B's heart stop beating at 9 weeks 5 days
    Our little miracle baby is a boy. :)

    Baby Boy Owen and Baby Girl Avery were born too early on Feb. 13, 2011 due to a pedunculated fibroid, incompetent cervix and suspected placental abruption.
    Lilypie Angel and Memorial tickers

    "What the heart has once owned and had, it shall never lose." - Henry Ward Beecher
    SAIF/PAIF Welcome
    Lots of love and luck to my PAIF/3T/IF Veteran ladies, especially my dear friend Zookie. Congrats to Papps, Teach84 and Starbuck on their little ones.
    Report Reply
  • reb259reb259 member
    My DE cycles were medicated.  I know Vanessa did a natural FET and I remember her saying that although it is a lot of monitoring, she like the process.  Hopefully she will chime in...
    I am AMA and all tests on H came back normal
    3 failed IVF with OE and 2 failed frozen DE cycles
    Last fresh hail mary DE cycle starting Feb 2013
    PAIF/SAIF always welcome
    Report Reply
  • vanessagorcvanessagorc member
    I did a natural fet to achieve this pregnancy.  U take nothing prior to the transfer.  U just go in for monitoring.  After u ovualte, the transfer is set for 5 days later (u take the steroids and antibiotics).  After the transfer, u do progesterone ( supps in my case bc u making ur own progesterone).  And that is it. 
    Warning No formatter is installed for the format bbhtml
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