Prophylactic antibiotics?

MrsRedVelvet

Did anyone's RE prescribe them antibiotics to  take prior to ER?  I've read mixed things about taking them vs not taking them.  The NIH published 1 study that had the rate of miscarriage increased when on Ab vs not.  It did worry me a bit to read that.

Thanks! 

Killer Tomato

I have to take them for 5 days starting the night of ER, and I'm not thrilled about it. (All these meds, and it is the antibiotics I feel strongest about!) I had a long discussion with my RE about it, and he said that, while rare, infections from the procedure can be nasty, and hurt future fertility. And I have been thinking about it, and I do think it will be nice to not have to worry if any post-ER cramping is the start of a deadly infection.

Do you have a link to that study? Statistics can be easily manipulated, and a lot of things go in to the validity of a study. A study based off of 200 pregnancies is going to be a lot less valid than one based off of 3000, for example. And even if one study shows a result, often other studies contradict it. So many variables. I would not worry.  

ShelleyBQ

I took them starting the night of ER for 4 days.

Bethany1026

I am pretty sure that I have been given antibiotics in the IV on the day of ER...I vaguely remember hearing them tell me that.

tryingtostaypositive

I've started taking two meds the night of ER

daiseydooda

My husband and I both were told to take antibiotics.

MrsRedVelvet

Killer Tomato:

I have to take them for 5 days starting the night of ER, and I'm not thrilled about it. (All these meds, and it is the antibiotics I feel strongest about!) I had a long discussion with my RE about it, and he said that, while rare, infections from the procedure can be nasty, and hurt future fertility. And I have been thinking about it, and I do think it will be nice to not have to worry if any post-ER cramping is the start of a deadly infection.

Do you have a link to that study? Statistics can be easily manipulated, and a lot of things go in to the validity of a study. A study based off of 200 pregnancies is going to be a lot less valid than one based off of 3000, for example. And even if one study shows a result, often other studies contradict it. So many variables. I would not worry.  

Thanks for the reply I can't seem to figure out to link on my iPad lol.  Try googling ivf prophylactic antiobiotics and it's on the NIH website.

I hear what your saying though.  I manage clinical trials for a pharma company and know all too well how these stats work lol.  But the p value does not lie which is why I was a little concerned.  I have my prep meeting tomorrow so I will ask my RE since I have been relying on Dr Google for now! (yes always a bad idea) 

Killer Tomato

MrsRedVelvet:

Killer Tomato:

I have to take them for 5 days starting the night of ER, and I'm not thrilled about it. (All these meds, and it is the antibiotics I feel strongest about!) I had a long discussion with my RE about it, and he said that, while rare, infections from the procedure can be nasty, and hurt future fertility. And I have been thinking about it, and I do think it will be nice to not have to worry if any post-ER cramping is the start of a deadly infection.

Do you have a link to that study? Statistics can be easily manipulated, and a lot of things go in to the validity of a study. A study based off of 200 pregnancies is going to be a lot less valid than one based off of 3000, for example. And even if one study shows a result, often other studies contradict it. So many variables. I would not worry.  

Thanks for the reply I can't seem to figure out to link on my iPad lol.  Try googling ivf prophylactic antiobiotics and it's on the NIH website.

I hear what your saying though.  I manage clinical trials for a pharma company and know all too well how these stats work lol.  But the p value does not lie which is why I was a little concerned.  I have my prep meeting tomorrow so I will ask my RE since I have been relying on Dr Google for now! (yes always a bad idea) 

The only one I could find was 

 https://www.ncbi.nlm.nih.gov/pubmed/15687942

(sorry, can't do clicky) and that can't be the one you are referring to, between the non-significant increase of miscarriage, the small sample size, and the fact that it studied antibiotics that are not the norm for prescribing. (Most REs do a z-pack or doxycycline, I believe.) 

If you only found one study, I wouldn't worry. People are complicated, IVF is complicated, and there are just too many variables to account for. If multiple large studies showed a correlation, I would worry, but not if one or two small ones did. Also, depending on when the study was done, protocols themselves have changed significantly. I never expected to be on some of the meds they are giving me, but they say success rates are better. If the antibiotics do have a negative effect, maybe the newer protocols counteract it. Let us know what your RE says...I am interested. 

brachatzipora

My husband takes Doxycycline starting the same time I start stims.  I take it once, the night before ER.

luvboston

yes I took them starting 5 days before

Maybe Joleisa

My RE's office usually prescribes 1gm of Zithromax to be taken the night before ER, but I'm allergic to erythromycin so I was prescribed 100mg of Doxy starting 2 days before ER for 7 days.

LaineyPaney

Hubby and I both have to take a 10 day course prior to ER. Starting on  day 3 of my last bcp pack. Then I take doxycycline again at the time of ER.

 

MBfromBMC

I was given Doxycycline twice per day for five days, but I didn't start taking it until after ER. I also had to take an oral steroid for swelling. DH didn't have to take anything. 

I am strongly against over-prescribing antibiotics, so I can see some of PP's points, but I haven't taken one since college, so I figured it was OK... 

Mayzie15

Yes I was prescribed the antibiotics and took them starting the night of ER and 4 days after...I wouldn't worry too much.