Infertility Veterans

wholly meds...

I know everyone is different and since I'm ancient(42)  that is my ovaries are ancient......

I'm sorta of stressing out about the mounting costs of the meds Im using this cycle. We are about $4000 in and I dont think we are close to the end. Tonight will be day 9 of injectables. Follies are a litlte slow and very difficult to see.....one side only one could be seen @ 6.7 small and poor.....the other side about five ranging from 7 to 9 some where........I don't think this is a great report?????? I will say Im pleased that there are more than 3 follicles.....but wholly six days of 450 gonalF and 75 menopur!!!!!  Come on, seriously ovaries....there are some decent bits in there, I know it!!!!! That is a lot of "drugs", is this not close to the max. esp of the gonal?

Still trying to stay positive on our final journey , "faith can still beat the odds"

 

**** really the sizes were measured @ day 8 ...slow but not as dissmal as I thought....still hope

TTC since 2009 very frustrated 42yr and DH 40

5 cycles of Clomid with satisfactory response=BFN's
Fibroid removal Nov2010
IUI Clomid #1 Feb 2011...BFN..damn it!
IUI Inject's #2 Apr 2011...CANCELLED...low estradiol
IUI Inject's #3 June 2011...BFN
IUI Inject's #4 Sept2011...BFFN
Lap Dec 2011...severe endo..cyst removed..some remains...
IVF#1 Apr 2012 ....cancelled due to over suppression
IVF#2 July 2012....6 follies...only 1 retrieved....BFFN
surgery suggested to move ovary to an better placement but....we moved two time zones away and are financially and emotionally empty

Re: wholly meds...

  • It does sound like a bit of a slow response to a lot of stims (my previous clinic's max. dose was 600 units). I hope they keep growing, and that slow and steady wins the race. Good luck.
    TTC #1 since June 2010
    Me: 36, DH: 42
    Dx: DOR and MFI

    DH: low count + very low motility; hormones all normal; Sperm DNA Frag. test = poor to fair; male karyotyping normal
    Me: FSH 13.4 + AMH 0.26 + hypothyroidism; Scratch the hypothyrodism (?); Blood clotting and immune panel all negative; endometrial biopsy normal

    IVF #1 (MDLF - Jul/Aug 2011): BFN (9R, 5M, 3F with ICSI, 3dt of 1 10-cell grade 2, no frosties)
    IVF #2 (EP-antagonist - Sep/Oct 2011): BFN (6R, 4M, 3F w/ ICSI, 3dt of 1 6-cell, 1 7-cell, grade 4s, no frosties)
    DE IVF #1 (shared cycle - June 2012): c/p (6R, 6F w/ICSI, 3dt 1 8-cell grade A- and 1 7-cell grade A-; no frosties)
    DE IVF #2 (shared cycle with new donor - Nov/Dec/ 2012): - BFP!!!!! 12/14/12. U/S on 12/27 shows twins!!!!!

    SAIFW/PAIFW
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  • Hugs.  Been there.  I'm afraid it's sounding like a slow response, but your follies could still pick up steam in the next couple of days if you can keep stimming.  At my clinic, they need to be 16mm to be considered mature.  I was always a late bloomer with growth of 3mm a day seen toward the end.  You're pretty close to what's considered max stims at my clinic (600iu).  Good luck!
    Baby girl Lila born 2013.
    Baby boy Henry born 2015.
    Expecting our capstone baby (boy) early March 2018.
  • I think it's great you have six in the running.  My response is very slow too. The cycle I stimmed the longest, I had the best graded embryos with very little fragmentation.  I really do think that slow is steady is the way for us AMA patients to go.  I stimmed for 17 days on that cycle with 600 of fsh.

    On another cycle I had slow growth and then around cd 10 my e2 stalled right around 400 with 4 follicles.  I knew it was to early to trigger but they told me it was time, I really wish I would have just cancelled that cycle.  

    I think as long as there is steady growth and your E2 is rising, slow is steady is a good thing.  Best of luck!

    TTC #1 since 9/07
    Dx MFI, AMA, Endo, AMH .16
    Lap 10/09 Removed endometrioma, stage IV endo and adhesions
    Lap 2/10 Endometrioma cysts & adhesions returned.
    Ivf #1 4/10 Antagonist, ET Cancelled.
    IVF #2 2/11 A/ACP+E2V C/P
    IVF #3 6/11 Letrozole/Antagonist BFN
    IVF #4 11/11 Low stim Antagonist BFN
    Lap 3/12 Lap & Selective HSG
    Many cycles of Letrozole and LP HCG w/TI and LDN
    IVF #5 8/12 Low stim BFN
    IUI #1 10/12 BFN br> S&PAIFW
  • Yep - slow ... but slow and steady wins the race. My dr once told me that stimming slower will produce a better egg than a fast stim. don't know how true that is but it made me feel better at the time. As far as the maximum dose goes, I think the amount of gonal-f you can take as a maximum depends on how much menopur you are on. I was on 3 - 4 vials of menopur a night so my max dose of gonal was 300 but I know women who have taken 450 2X a day with no menopur. I am sorry about the costs - that does bite. My meds total came to 8,700 (including the meds for DH which were under $50).

    I pray this is your cycle - good luck!

    TTC 1/2010 DH Dx - Azoospermia 2/2011
    Hysteroscopy 3/2011 2 Polyps removed 4/2011
    DH on Clomid / Arimidex to address hormonal issues - Sperm found July 2011!
    IVF #1 September 2011 - ER 9/8/2011- 8R, 5M - icsi - 1 made it to transfer - BFFN :-(
    IVF #2 Lucky November 2011 - ER 11/25/2011 - 15 eggs!, 13 mature, 10 fertilized with isci - 7 made it to transfer! Transferred 1 - 8 cell and 2 - 7 cell. BFP!!!!
    1st U/S - Twins! 2nd U/S - 3 heartbeats!!! - HOLY COW!!!
    Prayers for our take home babies!
    2 babies born on 3/27/12 and lost. Last baby born on 3/29/12 and lost at 20 weeks.
    My angels grew wings shortly after birth.
    Ahava Raisel, Matisyahu Nissim & Zev Chaim - Mommy and Daddy will always love you.
    IVF #3 July 2012 - ER 7/17/2012 - 10 R. 5 F. 4 made it to ET
    Transferred 2 on 7/20/2012 no snow babies :-(
    Beta on 7/31/2012 = BFMFN
    A miracle gift expected to come to us through adoption around 9/2012
    Baby girl adopted - Birth Mother changed her mind and took the baby back
    IVF #4 October 2012 - New RE. Doing PGD Testing. 8 R, 7F, 2 made it to 5 day blast for PDG testing. Both Normal (Thank you G-d!!!) 1 boy and 1 girl
    transferred one beautiful 5day blast (girl)
    Please G-d the almighty one - let this be our take home baby!
    Beta #1 158, Beta #2 318, 1 Absolutely magnificent HB at 175! Thank you G-d!!!
    Baby Girl born August 5th. Thank you G-d for our precious miracle.
    AMA. PAIF & SAIF always welcome - I need all the prayers I can get!

    Lilypie Angel and Memorial tickers
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