Survived my first pio shot...I've always done vaginal pergrestrone but with the mc last ivf cycle thy didn't wanna chance it...

After years of struggling with infertility issues (PCOS since I was 16) and 15 medicated cycles we finally got blessed with our son. We got lucky with our 7th IUI using stims...Now we are back on the roller coaster to try for another miracle..IVF cycle in May resulted in a chemical pregnancy. 2 snowbabies FET 7/16-transferred 2 blastocyst...Faint bfp 4dp5dt!
Re: PIO
Congrats. The 1st few doesn't seem that bad. My booty was bruised over time though.
Best wishes to you
Positive for HLA-B27, I'm a mutant
Testing - Me ok, gluten issue? DH - borderline count, low motility
4/28/11 IUI#1 = BFP!(5/25), EDD 2/2/12 - m/c 5w3d
7/3, 7/31, 9/25 - IUI#2-4=BFN
IVF#1 - 1 blast = BFP!! (12/30), EDD 9/9/12, confirmed c/p 4w2d
FET#1 3/2/12 - 2 blasts =BFP!! EDD 11/18/12, us#1 = twins! Confirmed m/c 5w6d
4/20-surprise BFP and another c/p 4w2d
FET#2 7/16/12 - 2 blasts = BFN
FET#3 8/20/12 - 1 blast - BFP!! Beta #1-2=177, 354
1st u/s 5w6d, one beautiful little HB
baby girl born 5/10/13
TTC#2 since 12/17/2014, Cycle 8
Repeat Testing...FSH=12, AMH=3.8, AFC=28.
IUI#5 5/10/15- c/p?
IVF#2 8/19/15 - cancelled due to cysts
IVF#2 take two 10/2015 - 5 blasts frozen
FET#4 12/11/2015 - BFN - 4 blasts remaining
FET#5 2/18/16 - BFP!!! Beta1-3, 126, 250, 745!!
Tons of love and ((hugs)) to my IF sister NMscubagirl
With how strong of a girl you are, you would be totally fine. I am such a wimp and I actually prefer PIO over suppositories after having done both now. As long as you donthem right it is not bad at all!
04/07/11- PCOS Diagnosis w/GYN. Put on Metformin (1500 mgs)
04/25/11- 1st consultation with RE (Confirmed PCOS & Anovulation)
05/09/11-HSG-All clear! 05/13/11-SA-Normal. Found out on 2/14/12, low Morph (1%).
06/17/11-10 days of Clomid (100, 150) No response.
07/10/11-03/20/12- 5 Injectable (Follistim) IUI cycles; 4 BFN, 1 C/P. (stims ranged from 11 days to 25 days)
05/28/12-Diagnosed with Hypothyroidism. 75 mcg Synthroid.
IVF with ICSI in June/July 2013 = BFP!. Beta # 1 = 123. Beta # 2 = 252. Due March 25th. Baby boy arrived March 27, 2013!
FET #1 - 10/4/14 = BFP!! Beta #1 = 179. Beta # 2 = 499. Due June 22nd.

PIO is hit or miss for me. I had some that were easy and others that were painful and one that produced quite a bit of blood. I have learned to ice really well - for like 20 minutes. That seems to help. I am 12 days in.
It is actually better to use moist heat for 10 min prior and 10 min after, while massaging. My nurse said that it helps the progesterone make its way through your muscles better and prevents knots. She said ice can keep it trapped in the muscle. I put a wet wash cloth in the microwave and keep reheating it. But, everyone has their own method that works for them as well ??
Agreed. You are supposed to use heat, not ice.
04/07/11- PCOS Diagnosis w/GYN. Put on Metformin (1500 mgs)
04/25/11- 1st consultation with RE (Confirmed PCOS & Anovulation)
05/09/11-HSG-All clear! 05/13/11-SA-Normal. Found out on 2/14/12, low Morph (1%).
06/17/11-10 days of Clomid (100, 150) No response.
07/10/11-03/20/12- 5 Injectable (Follistim) IUI cycles; 4 BFN, 1 C/P. (stims ranged from 11 days to 25 days)
05/28/12-Diagnosed with Hypothyroidism. 75 mcg Synthroid.
IVF with ICSI in June/July 2013 = BFP!. Beta # 1 = 123. Beta # 2 = 252. Due March 25th. Baby boy arrived March 27, 2013!
FET #1 - 10/4/14 = BFP!! Beta #1 = 179. Beta # 2 = 499. Due June 22nd.

I have heard that but my RE said to use ice. My issue is that it hurts when the needle is inserted only. My DH rubs with a hot washcloth afterwards and I use a heating pad. So far zero lumps just that painful initial needle prick. I will try heat before and see but the last 2 ice icing long seemed to help.
If it helps, then I would say to continue doing it! Whatever you can do to make the process easier!
Hopefully the ELMA cream helps you out.
04/07/11- PCOS Diagnosis w/GYN. Put on Metformin (1500 mgs)
04/25/11- 1st consultation with RE (Confirmed PCOS & Anovulation)
05/09/11-HSG-All clear! 05/13/11-SA-Normal. Found out on 2/14/12, low Morph (1%).
06/17/11-10 days of Clomid (100, 150) No response.
07/10/11-03/20/12- 5 Injectable (Follistim) IUI cycles; 4 BFN, 1 C/P. (stims ranged from 11 days to 25 days)
05/28/12-Diagnosed with Hypothyroidism. 75 mcg Synthroid.
IVF with ICSI in June/July 2013 = BFP!. Beta # 1 = 123. Beta # 2 = 252. Due March 25th. Baby boy arrived March 27, 2013!
FET #1 - 10/4/14 = BFP!! Beta #1 = 179. Beta # 2 = 499. Due June 22nd.
