TTC after 35

Questions for you all :)

Ok so we have been TTC going on 2 years now ... My questions is does anyone know what the next step is following  1) Clomid not working 2) HSG complete.  I was hopeful this month due to the fact I was a couple days late but of course AF showed up today ... I was expecting it but well you all know what I mean :)   Have been temp-ing etc.  Are there other tests that can be done?

Re: Questions for you all :)

  • When you say that Clomid is not working, have you been monitored?  You can only take Clomid six cycles in your lifetime - there are serious risks to taking more.  I skipped Clomid and went straight to Femara since my RE finds that Clomid has more side effects and is less effective for women older than 35.  I started with a 2.5 mg dose, then 5.0 mg, and finally 7.5 mg this cycle. 

    Have you had your CD3 bloodwork done?  Your RE would have ordered these.  What about a SA (semen analysis)? 

    An RE can best help you figure out what is going on.  I know it is more expensive, but they are the experts in getting people pregnant, so it is worth it.  Good luck!

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  • I agree with the pp.  If you haven't seen an RE yet then just start there and they will give you some guidance as to your next step.  There are many things that could be going on and they could test for.  Good luck!
    TTC since Dec. 2010. Me: 37, DH: 38...unexplained RPL
    BFP #1 - missed m/c 4.18.11 found @8w3d, d&c @13w 
    BFP #2 blighted ovum found 8.2011 @8w, misoprostol
    BFP#3 - missed m/c 6.11.12 @ 9w3d, d&c revealed extra chromosome 15
    BFP#4 8.10.12, DD born 4/26/13
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  • imageShellBear+:
    I agree with the pp.  If you haven't seen an RE yet then just start there and they will give you some guidance as to your next step.  There are many things that could be going on and they could test for.  Good luck!


    Me 39 & suspected PCOS, DH 42. Went off BCP when we got married in 11/11, seriously TTC since 3/12.  Six cycles of clomid = BFNs.  Suspected endometriosis & HSG showed both tubes blocked.  Sept 2013 IVF 5D transfer of two perfect embryos = BFN.  Started acupuncture and taking time off to drop some pounds & get healthier before FET in April 2014.
  • PPs have said it best. There's a whole lot of additional testing you could do, and it is generally best done through an RE.
    TTC #1 since June 2010
    Me: 36, DH: 42
    Dx: DOR and MFI

    DH: low count + very low motility; hormones all normal; Sperm DNA Frag. test = poor to fair; male karyotyping normal
    Me: FSH 13.4 + AMH 0.26 + hypothyroidism; Scratch the hypothyrodism (?); Blood clotting and immune panel all negative; endometrial biopsy normal

    IVF #1 (MDLF - Jul/Aug 2011): BFN (9R, 5M, 3F with ICSI, 3dt of 1 10-cell grade 2, no frosties)
    IVF #2 (EP-antagonist - Sep/Oct 2011): BFN (6R, 4M, 3F w/ ICSI, 3dt of 1 6-cell, 1 7-cell, grade 4s, no frosties)
    DE IVF #1 (shared cycle - June 2012): c/p (6R, 6F w/ICSI, 3dt 1 8-cell grade A- and 1 7-cell grade A-; no frosties)
    DE IVF #2 (shared cycle with new donor - Nov/Dec/ 2012): - BFP!!!!! 12/14/12. U/S on 12/27 shows twins!!!!!

  • I agree with others - an RE appt would be your best bet - if you start with your OB they will have you start testing - but a lot of times once you see an RE they will have your repeat the tests again.  Good Luck.

    Me 38 MH 41 - TTC since June 2010 - dx with Severe MFI. Straight to IVF with ICSI. IVF #1 - ER 06/13/12 - 9 Eggs Retrieved - 4 ICSI'd - only 2 fert. 06/15/12 - 2DT - 3 cell & 6 cell with fragmentation. Beta 06/29/12 - IVF #1 = BFN. 07/20/12 - WTF Appt -Told by our RE to quit IVF. Second Opinion from RE is good. IVF#2 - November 2012. Estradiol Pills Started 11/6. Stims start 11/16. ER 11/26 - 7 eggs retrieved - all mature. 4 fertilized with ICSI. ET 11/29 Transferred 3 embryos. Beta is 12/10. 1st Beta 81 2nd Beta 160 and 3rd beta 360!!! First U/S 12/21/12 - We saw one beautiful gest. sac. 2nd U/S is 01/04/2013 - H/B 183 02/05/13 - NT Scan - everything looks good and IT'S A BOY!  Aiden was born 08/20/2013.

    IVF #2 is in progress.  ER was 05/12/14 - 11 eggs retrieved, 8 fertilized with ICSI.  ET was 05/15/14 - we transferred 3 embryos as we did on the cycle my son was conceived.  We were able to freeze 3 embryos. Beta is scheduled for 05/26/14.  1st beta - 111.  2nd beta - 159 didn't double :( 3rd beta Friday 5/30) - not a lot of hope left. Beta # 3 is 247 - probably ectopic.  Beta # 4 is 813 - possibly vanishing multiple sydrome?  06/05/14 - 5w4days - first U/S - we see a gestational sac and yolk - still have hope!  06/17/14 - 7w1day - U/S and saw and heard the heartbeat - Finally!  06/27/14 - 8w4days - Baby and heartbeat look and sound great :)  EDD 02/01/14 and It's a boy!

     "Everything will be okay in the end. If it's not okay, it's not the end."


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  • Thank you all for the comments :)  I do appreciate any and all feedback.

     We tried Clomid for 5 cycles...also have had a SA which was totally fine as well...Meeting back with RE on Monday to see what is next ... I was just wondering what else they could possible do...We are not wanting to do IVF...So is this the end of the road unless by some miracle we can get prego? :) 

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