This cycle really isn't going well at all. I am so frustrated and sad. Today is day 9 of stims. My right ovary is on vacation and not doing much of anything at all. My left is doing ok, but I will be surprised if we get more than 5-6 eggs. I am now on 2x the amount of stims I've ever been on before. I am not sure why my response has tanked this time around. My progesterone unfortunately rose a lot today, which is probably the biggest of my problems, since premature luteinization is associated with lower pg rates (the idea is that the premature rise in progesterone matures the lining out of phase with the stage of development of the embryo).
My understanding from my RE is that this means a fresh transfer is out. In addition, there is now some fluid in my uterus as well as a small echogenic area (thought to perhaps be the last remnants of retained placenta after my operative hysteroscopy). Lastly, my lining has inexplicably become thinner instead of thicker. I don't even know how that is possible (!).
The plan now is to trigger on Friday for a Sunday retrieval. My RE doesn't think he will get many eggs but wants to cut our losses at this point and not go much further since the rising progesterone is a problem. Also, I saw my hematologist yesterday andthe pathology came back with clots in the twins' placentas so we will now do the clotting tests, but even if I have a clotting disorder I am not a candidate for clexane/lovenox due to my bleeding disorder. I am also feeling a little stressed out about that. I wish this didn't have to be so freaking hard and I know this is just the beginning.
Re: this cycle is a disaster
06.10.12 +HPT 06.12.12 Beta #1 = 2,770 06.14.12 Beta #2 = 6,300
1st U/S 06.18.12 2nd U/S 06.25.12
09.24.12 It's a Boy!! ---> Jacob Owen
Our IF Journey Began: October 2009
**8 Failed IUI's, 1 Blighted Ovum, & 1 Failed IVF**
Dx: MFI, DOR w/MTHFR Homozygous A1298C & Hypothyroidism
03.2012 Lab Results: FSH 6.83 AMH 0.67 TSH 3.8 E2 17
SA 156 million 93% motility 3% morphology
**~PAIF/SAIF Always Welcome~**
Early loss 10/08
Lap 1/09
IVF #1 "natural IVF" - 1 egg retrieved, missed m/c
Tried several mini-stim cycles with no response
Switched clinics - dx'd as carrier for Fragile X
IVF #2 MDL protocol Jan/Feb converted to IUI, BFN
IVF #2 take 2: Antagonist, one embie, BFN
IVF #3: Antagonist, no fertilization
One last ditch effort at OE IVF (antagonist with Clomid) cancelled
DE cycle #1 Jan/Feb 2011, BFP, ectopic
DE cycle #2 June/July 2011 - BFP
10/28/11 Baby girl lost at 17 weeks due to pre-term labor. We love and miss you.
DE cycle #3 June/July 2012 - BFP, twins, both heartbeats stopped, D&C
2 frosties but don't know what's next
FET Dec 2012: BFP! Praying this one sticks for the long haul!
I'm so sorry! I am keeping my fingers crossed that things turn around!!!
(((Huge Hugs)))
::: Married June 2003:::

TTC #1 since: Aug. 2008
Me: 34, DOR, MTHFR-A1298C (heterozygous), decreased blood flow to uterus, Mild Endo
DH: 38, Balanced translocation 5&10, unexplained MFI, normal SA and SCSA
Tx History: IUI 1&2= BFN
IVF# 1 W/ICSI= BFN
IVF# 2: cancelled d/t no response
IVF# 3= 1 egg retrieved=immature/not viable
IVF# 4= c/p
***CCRM ODWU***
Found DHs BT and Me-decreased blood flow to uterus
Recommended DE IVF w/PGD, incorporate electro-acupuncture. Decided to cycle locally
***New RE***
DE IVF# 1(cycle #6) w/pgd, (freeze all): 30R, 23M, 15F, slow/poor embryo development, 4 biopsied, 1 Normal "Norm"; DE IVF w/PGD, incorporate electro-acupuncture.
IVF# 6: (OE/DS) cancelled
IVF# 7: (OE/DS) 1R, 1M, 1F, arrested day 5
Plan-DE IVF# 2 (cycle #8): DE/DS in May 2015
http://icanhazbabyz.blogspot.com/
3 failed IVF with OE and 2 failed frozen DE cycles
Last fresh hail mary DE cycle starting Feb 2013
PAIF/SAIF always welcome
I'm so sorry, Sweetie ((BIG HUGS)) After everything you've been through I wish this could just go according to plan.
I hope they get some good eggs on Sunday and that you can get some answers with your upcoming tests.
Me: 32 - Stage II Endo / DH: 36 - Low count and morphology (1%)
IUIs 1-3 BFN, lap Dec. 2010, IUIs 4-6 BFN
IVF w/ICSI #1 - ER 2/8: 24R 19M 9F ET 2/13 2-5 day blasts (no frosties) = BFP - b/g twins!
E & C Born 10/19/2012
i'm sorry cutie.
i hope everything works out.
((HUGS))
Worrying does not empty tomorrow of its troubles, It empties today of its strength. ~Corrie ten Boom
Courage doesn't always roar. Sometimes courage is the little voice at the end of the day that says I'll try again tomorrow. ~Mary Anne Radmacher (thank you beadinglady)
It's been a long journey. TTC since 9/06. multiple IUI's and IVF's and 4 m/c's. IVF#3 = BFP, twins, induced at 34w6d due to baby b passing away (no explanation). Delivered on 35w1d, Baby A - baby girl, and Baby B - baby boy, our little angel.
MTHFR A1298C & C677T, Immune Issues and Factor II
Me: PCOS, Blood/Immune Issues DH: Low all 3
Jun.- Sep. 2010 IUI#1-#3 = BFN
Oct. 2010 = IVF #1 = B/G Twins (passed away Feb. 2011)
May 2011 = Myomectomy and trans-abdominal cerclage (TAC)
Sep. 2011 = Surprise BFP = C/P
Feb. 2012 = sFET #1 = BFN
Feb.2012 = Hail Mary IUI #4 = BFN
April/May 2012 = FET #2 w/our last two embies = BFP (Please let this be it!)
Beta #1 8dp5/6dt = 234 Beta #2 10dp5/6dt = 695 Beta #3 12dp5/6dt = 1796 Beta #4 17dp5/6dt = 17,888 U/S #1 May 17, 2012 = Twins
Baby B's heart stop beating at 9 weeks 5 days
Our little miracle baby is a boy.
Baby Boy Owen and Baby Girl Avery were born too early on Feb. 13, 2011 due to a pedunculated fibroid, incompetent cervix and suspected placental abruption.
"What the heart has once owned and had, it shall never lose." - Henry Ward Beecher
SAIF/PAIF Welcome
Lots of love and luck to my PAIF/3T/IF Veteran ladies, especially my dear friend Zookie. Congrats to Papps, Teach84 and Starbuck on their little ones.
Hugs!!!!
I had a cycle where I had no response at all, after 7 days. My e2 was only 92. I ended up on max Stims and triggered after 13 days of Stims. It ended up yielding a good egg count, and we weren't expecting much at all.
Are u thinking of cancelling? I know I was. Praying for a good outcome.
(((hugs)))
I'm sorry this cycle is not going as planned.
DX: 6/9/2011: Azoo ICSI/IVF only option for biological child
IVF #1: ER - 9/26 * ET - 10/1 * beta#1 10/13 - 140 * beta#2 10/17 - 477 * beta#3 10/20 - 1101
1st u/s at 6w6d - one hb * 2nd u/s at 8w3d - no hb detected 11/10/11 * natural m/c 11/13/11
FET #1 Jan/Feb 2012 - 3 delays - cancelled 2/13
FET #1.2 - May/June 2012 - ET 6/6/* beta#1 6/15 - 95 * beta #2 6/19 - 322 * beta #3 6/22 - 940
7/6 1st u/s @ 7 weeks - one beautiful hb - released from RE
EDD 2/22/2013
PAIF/SAIF/PGAL welcome
IVF #1 w ICSI in July 2010 = BFN
IVF #2.1 in Oct 2010 converted to IUI = BFN
IVF #2.2 w ICSI in Dec 2010 = BFN
Met with new RE in new city on 1/31/11.
IVF #3 w ICSI in April 2011. HPT on 5/9 = BFP!
Beta #1 on 5/10 (10dp5dt) = 99.4. Beta #2 on 5/12 = 284. First u/s on 5/26. = Fraternal TWINS!
Twin boys born & lost on 8/16/11 at 18w1d due to PPROM & preterm labor.
IVF #4.1 in Jan 2012 converted to IUI on 1/7/12 = BFN
IVF #4.2 w ICSI in Feb 2012. Lupron on 2/10. Stims on 2/18. ER on 2/29- 7R,6F
ET scheduled for 3/5/12- nothing to transfer
Dh seeing new MFI uro & Dh starting meds- June 2012.
IVF #5 in Dec 2012 = BFFN.
IVF #6 planned for Spring 2013. Praying for our take home baby/ies.
**P/SAIF and P/SAL always welcome!**
Ugh, so much stress! I'm sorry, blue
All I can think is maybe the decision will be made for you whether you wanted to freeze or do a fresh transfer this cycle. Hopefully, even if you only get a handful of eggs, they'll be GREAT ones. Big ((HUGS)) to you both right now xoxo
I really suck at staying pregnant
FET #1 Dec 2013 BFN
FET # 2 Feb 2014 BFN
No more frosties
IVF #2. September 2014
PGD yielded 2 perfect 5d blasts
SET November 9, 2014
Nov 23, 2014. Another BFN
Not sure where to go from here.
2/06 - surprise pregnancy - twins
3/06 - m/c 1st baby at 6 weeks
5/06 -2nd baby had no heartbeat at 14 wks.
D&E - Bled out. Blood transfusions. Week in ICU - Cheated Death!
Diagnosis: Blood clotting and bleeding disorder, immune issues, & cervical stenosis
5/10 - 1st IVF cycle - BFN
FET - 10/12/10 - BFN
1/11 - IVF with PGD - BFN
IVF - May - BFN
6/11 New RE - fingers crossed!
9/11 - IVF - 4 transferred
10/13 - BFP!!
It's a boy! Clint Michael, Due in June!!!
Baby boy Henry born 2015.
Expecting our capstone baby (boy) early March 2018.
Positive for HLA-B27, I'm a mutant
Testing - Me ok, gluten issue? DH - borderline count, low motility
4/28/11 IUI#1 = BFP!(5/25), EDD 2/2/12 - m/c 5w3d
7/3, 7/31, 9/25 - IUI#2-4=BFN
IVF#1 - 1 blast = BFP!! (12/30), EDD 9/9/12, confirmed c/p 4w2d
FET#1 3/2/12 - 2 blasts =BFP!! EDD 11/18/12, us#1 = twins! Confirmed m/c 5w6d
4/20-surprise BFP and another c/p 4w2d
FET#2 7/16/12 - 2 blasts = BFN
FET#3 8/20/12 - 1 blast - BFP!! Beta #1-2=177, 354
1st u/s 5w6d, one beautiful little HB
baby girl born 5/10/13
TTC#2 since 12/17/2014, Cycle 8
Repeat Testing...FSH=12, AMH=3.8, AFC=28.
IUI#5 5/10/15- c/p?
IVF#2 8/19/15 - cancelled due to cysts
IVF#2 take two 10/2015 - 5 blasts frozen
FET#4 12/11/2015 - BFN - 4 blasts remaining
FET#5 2/18/16 - BFP!!! Beta1-3, 126, 250, 745!!
Tons of love and ((hugs)) to my IF sister NMscubagirl
I am so sorry!! I can't stand how hard it is, it's just terribly unfair.
I had the same progesterone problem with my first IVF, we froze the 2 embies we got from it and xferred them later. They were of better quality than the 2 we got from IVF2, fwiw.
Wishing you beautiful quality eggs and embies from this difficult cycle!!
Callan George and Bennett Charles born and died 11/7/10
FET #1 April 2011= BFN
FET #2 July 2011= no transfer because my lining sucked
FET #3 February 2012= BFP! 1st beta 9dp5dt=314 2nd beta 11dp5dt=977 1st U/S 3/20 Twins- Heart rates of 111 and 138
Living After Losing
IVF #1 = BFN
FET #1 = BFN
FET #2 = BFN
IVF #2 = BFP, b/g twins lost at 20w due to partial abruption/PPROM
IVF #3 = c/p 5w2d
Long-shot Clomid/Prednisone cycle before next IVF = BFP, our beautiful, healthy girl born 6/26/13!
~~
TTC again March 2014
FET #3 - May/June 2014 - all embryos arrested before xfer - back to the drawing board...
IVF #4 - July/August 2014