Trouble TTC

pituitary microadenoma

Just wondering if anyone has been diagnosed with this.  Mine is very small but my dad did some research and 1 in 5 people may have a small tumor on their pituitary. I thought I just had post pill amenorrhea because nothing happened after I got of birth control when we TTC.  My NP prescribed progesterone after three months.  Nothing happened so I went to a doctor who prescribed estrogen for 21 days and than provera again and I was also diagnosed with hypothalamic hypopituitary.  I have the progesterone levels of a menopausal women but the rest were in normal range.  Than the MRI showed a small lesion or cyst or tumor on my pituitary.  Now I've finished the last batch of provera and no period.  I have a prescription for I have also tried to gain a little weight and work out less. My doctor referred me to the fertility clinic.  I do have a prescription for Letrozole when I start my cycle. Does anyone have anything similar happening to them.  I'm a bit confused as why on BC I got my period fine but with the estrogen progestin combo nothing is happening.

Re: pituitary microadenoma

  • I just wanted to say hello and good luck! I don't have a tumor on the pituitary, mine just chooses not to function on its own accord. Since symptoms are similar I thought I'd send a hello. I've been panhypopit since around age 10 so if you have any pituitary questions let me know!
    Me: 33, Endocrine issues & FVL       DH: 32, Nothing 
    NTNP 2009-2012         TTC since 2012:
    • Clomid, 2 IUI cycles, and 5 IVF cycles = BFN
    • FET #1   August 2013 = BFP!     EDD 5/11/14
    • Jack dx at 19w1d with Dandy Walker on 12/16/13
    • Severe Pre-e /HELLP set in Jack born sleeping at 20w1d on 12/23/13
    • FET #2 --July 2014  BFP!  ---  EDD  4/5/15

    Jack has handpicked his sibling up there :)

    My blog about IF and loss ... Kate's IF Blog

            Lilypie Angel and Memorial tickers 

                                                      

                                                                              Lilypie Pregnancy tickers


                  Anniversary





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  • Thank you, good luck to you!
  • I actually have a pituitary macroadenoma that is a prolactinoma (1.5cm by 1.5 cm).  I got my period on bc also but never got it when I went off.  Still haven't actually.  I am currently on provera for the first time so we will see what happens after 6 more days. Pituitary adenomas are somewhat common and usually incidental findings on MRIs or autopsy.  I take cabergoline 2x per week and it shrunk.  I am just starting TTC but my ob referred me to an RE when I saw her last week.  I am going on May 1st. I think that you get your period when you are BC because you are given estrogen via BC and with the withdrawal of hormones each month you menstruated.  It may mean that your estrogen is low. If women who  take provera and  have adequate endogenous estrogen, it transforms proliferative into secretory endometrium which then you menstruate.

    <Image and video hosting by TinyPic
    Married June 2011 Dx: anovulatory due to prolactinoma (1.5cmx 1.5cm in 2006)
    April 2012: MRI- questionable cyst 8mg by 12mm in pituitary ; referred to RE by Ob-gyn after amenorrhea x 4+ months, provera ineffective, low estrogen level
    cycle 1: May 2012, clomid 50mg; cycle cancelled, thin lining, no response
    cycle 2: June 2012, femara 5mg; cycle cancelled, no response
    cycle 3: July 2012, femara 7.5mg; cycle cancelled (largest folli on Cd12 & cd 16: 11, lining 4)
    Repeat MRI July 25,2012- Cyst unchanged, likely old infarction.
    Aug. 8: met with RE, move to injectables if HSG and SA normal
    Aug. 23: HSG all clear; DH- perfect
    Switched to a new RE in early Sept. IVF here we come
    Genetic testing reveals: Fragile X- Intermediate risk/grey zone.
    IVF#1: ER 11/30: 14 retrieved, 10 mature, 7 fertilized. E2 prior to trigger 5200. Decision made to freeze 6 embryos and transfer later due to OHSS.
    IVF#1.2/FET #1: estrogen injects start 1/18, FET delayed to try to thicken lining. lining 5.4mm. FET- 2/18- transferred one 3AA expanded blast. BFP 5dp5dt. Beta #1- 2/27 9dp5dt- 102.27 beta #2 3/1: 147 :(, beta #3 3/4: 268 told to stop meds and let nature take its course. requested 4th beta (3/6); Beta hell for 2 months.

    FET # 2: endometrial scratch 5/6, added estrace vaginally and ASA to delestrogen and PIO. June 10- transferred one 4AA hatched embryo, BFP 4dp6dt, Beta 1 (9dp6dt) 187, Beta 2 (11dp6dt): 412; Beta 3 (15dp6dt ): 4452. U/S #1- one beautiful embryo with a heartbeat of 133 at 7 weeks.  8 weeks: heartbeat 156. EDD 2/26/2014: born 2-3-14 induced due to Pre-E and HELLP at 36w5d.

    12/1: met with RE to discuss trying for #2


  • Your right I do have low estrogen levels so this time I was taking estorgen for 21 days prior to taking provera but it still hasn't worked for me.  Very strange.  I'm very tempted to just take a couple BC pills to start things up so I can start letrozole but I'm thinking that wouldn't work.  I just have been trying to be patient since I realized somthing was wrong in December.  Thanks for the info.
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