So, we got DH's DNA/Sperm fragmentation test results today...and everything is NORMAL. We were totally expecting bad news, as the RE led us to believe that there is a sperm issue (besides low count) that was causing our embryos not to make it past day 5.
Now I am wondering if it is my eggs. Except all my testing came back normal an my AMH is in the low normal range.
This is so frustrating...if we are both fairly normal, WTF have we had 4 failed IVFs? I have a call into RE to schedule appointment to discuss the test results and next step.
I am kind of relieved...if I had to pick between donor sperm and donor eggs, I'd prefer donor eggs. That way, I would get to carry a child that belonged to my DH. Yet, we were both prepared to talk about the donor sperm route.
And the ride on the IF rollercoaster continues...
Re: Test Results
06.10.12 +HPT 06.12.12 Beta #1 = 2,770 06.14.12 Beta #2 = 6,300
1st U/S 06.18.12 2nd U/S 06.25.12
09.24.12 It's a Boy!! ---> Jacob Owen
Our IF Journey Began: October 2009
**8 Failed IUI's, 1 Blighted Ovum, & 1 Failed IVF**
Dx: MFI, DOR w/MTHFR Homozygous A1298C & Hypothyroidism
03.2012 Lab Results: FSH 6.83 AMH 0.67 TSH 3.8 E2 17
SA 156 million 93% motility 3% morphology
**~PAIF/SAIF Always Welcome~**
TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
5 IUI's: 2/11 to 6/11 and 1/12= BFN
OE IVF#1-4 8/11-6/12= all BFN
DE IVF#1 11/12 bad embryos= BFN
DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
DE IVF #3 1/14 ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d
DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!
K & K born 11/21/14 at 38wks 4 days
SAIF/PAIF Welcome
http://waitingforraintostop.wordpress.com
Ugh -- not even sure what to say here. Congratulations on normal sperm!! But so frustrating to have no answers! :-[ Really hoping that the RE has a great plan for moving forward!
ditto above
i hope you get some answers and a plan
Worrying does not empty tomorrow of its troubles, It empties today of its strength. ~Corrie ten Boom
Courage doesn't always roar. Sometimes courage is the little voice at the end of the day that says I'll try again tomorrow. ~Mary Anne Radmacher (thank you beadinglady)
It's been a long journey. TTC since 9/06. multiple IUI's and IVF's and 4 m/c's. IVF#3 = BFP, twins, induced at 34w6d due to baby b passing away (no explanation). Delivered on 35w1d, Baby A - baby girl, and Baby B - baby boy, our little angel.
MTHFR A1298C & C677T, Immune Issues and Factor II
Glad to hear the sperm is ok. Only thing I will say is that my levels are all within normal to high normal range but I am almost 39 so that alone is an "issue"
Each RE has offered to cycle me with my own eggs but I still have a low % of getting pregnant vs using DE. I think it is like 36% for a perfect cycle with my OE vs 60some% using DE.
Good luck, I know it is a lot of hard decisons, none of which seem like they will actually even work. The is a DE/DS FB page. If you want me to add you let me know. There is a lot of good info on it.
3 failed IVF with OE and 2 failed frozen DE cycles
Last fresh hail mary DE cycle starting Feb 2013
PAIF/SAIF always welcome
IVF #1 w ICSI in July 2010 = BFN
IVF #2.1 in Oct 2010 converted to IUI = BFN
IVF #2.2 w ICSI in Dec 2010 = BFN
Met with new RE in new city on 1/31/11.
IVF #3 w ICSI in April 2011. HPT on 5/9 = BFP!
Beta #1 on 5/10 (10dp5dt) = 99.4. Beta #2 on 5/12 = 284. First u/s on 5/26. = Fraternal TWINS!
Twin boys born & lost on 8/16/11 at 18w1d due to PPROM & preterm labor.
IVF #4.1 in Jan 2012 converted to IUI on 1/7/12 = BFN
IVF #4.2 w ICSI in Feb 2012. Lupron on 2/10. Stims on 2/18. ER on 2/29- 7R,6F
ET scheduled for 3/5/12- nothing to transfer
Dh seeing new MFI uro & Dh starting meds- June 2012.
IVF #5 in Dec 2012 = BFFN.
IVF #6 planned for Spring 2013. Praying for our take home baby/ies.
**P/SAIF and P/SAL always welcome!**
Positive for HLA-B27, I'm a mutant
Testing - Me ok, gluten issue? DH - borderline count, low motility
4/28/11 IUI#1 = BFP!(5/25), EDD 2/2/12 - m/c 5w3d
7/3, 7/31, 9/25 - IUI#2-4=BFN
IVF#1 - 1 blast = BFP!! (12/30), EDD 9/9/12, confirmed c/p 4w2d
FET#1 3/2/12 - 2 blasts =BFP!! EDD 11/18/12, us#1 = twins! Confirmed m/c 5w6d
4/20-surprise BFP and another c/p 4w2d
FET#2 7/16/12 - 2 blasts = BFN
FET#3 8/20/12 - 1 blast - BFP!! Beta #1-2=177, 354
1st u/s 5w6d, one beautiful little HB
baby girl born 5/10/13
TTC#2 since 12/17/2014, Cycle 8
Repeat Testing...FSH=12, AMH=3.8, AFC=28.
IUI#5 5/10/15- c/p?
IVF#2 8/19/15 - cancelled due to cysts
IVF#2 take two 10/2015 - 5 blasts frozen
FET#4 12/11/2015 - BFN - 4 blasts remaining
FET#5 2/18/16 - BFP!!! Beta1-3, 126, 250, 745!!
Tons of love and ((hugs)) to my IF sister NMscubagirl
I am glad they came back normal, but sad for you too. That sucks they just don't know. We are in the same boat. How much did your DH's tests cost? we are totally OOP, even for normal stuff till we hit 4k. Stupid HSA. Nothing from the last cycle counted either.
I hope the RE can give you some insight. I also would do donor eggs in a heartbeat. I just want a baby so bad.
TTC since 2007
6 IUIs, 3 IVFs, and 2 m/c :< PCOS, Blood Clotting Disorder & MFI
IVF #2 Aug 2011 is a BFN:<
IVF #3 March 2012 is a BFN
Not sure what to do now. Sad and lost.
lurking...
We've had 3 failed IVFs and I think our next step is to try an IVF where we split the eggs between my husbands and donor sperm. This should give us the answer as to whether the problem is the sperm or the egg. We've actually never done the frag test - and my RE doesn't think there is a point in doing it b/c whether the result is bad or good she would still recommend the same course of treatment. I hate how hard all of this is - and I wish there were some easier answers.
((huge hugs))
Dx: PCOS and MFI
3 IUIs, 4 IVFs = BFFN
3rd RE: IVF #5/FET = BFP
14dp5dt=1170 16dp5dt=2573
1st u/s=TWINS!
It's a Boy and a Girl!
Born at 34w3d!
Ditto
7 IUIs = All BFNs
2011: March IVF #1.2 = e/p @ 6w: May IVF #2 = BFN: July sFET #1 = BFN
2012: Jan We're Certified FC/A Parents
May IVF #3 = c/p
June-Nov Foster Mommy to M (Toddler)
July FET #2 = BFN
Aug FET #3 = BFN
Sept-Nov Foster Mommy to Baby Bella (Newborn)
Nov HSG/Sono = Clear!
Dec FET #4 = BFN
2013: Feb FET #5 = m/c @ 6.5w
May-July Foster Mom to H (8 yr old girl)
June/July/Aug IVF #4 = Freeze All
July = Unofficially Adopting T (10 yr old boy)
Sept FET #6 = TBD
**PAIF/SAIF Welcome**
I have to agree with this as well. Sometimes all it takes is a new set of eyes and a different lab.
I know how frustrating it can be. Big hugs!
2/06 - surprise pregnancy - twins
3/06 - m/c 1st baby at 6 weeks
5/06 -2nd baby had no heartbeat at 14 wks.
D&E - Bled out. Blood transfusions. Week in ICU - Cheated Death!
Diagnosis: Blood clotting and bleeding disorder, immune issues, & cervical stenosis
5/10 - 1st IVF cycle - BFN
FET - 10/12/10 - BFN
1/11 - IVF with PGD - BFN
IVF - May - BFN
6/11 New RE - fingers crossed!
9/11 - IVF - 4 transferred
10/13 - BFP!!
It's a boy! Clint Michael, Due in June!!!
I'm sorry you didn't get more answers. That was our issue, too. We were dealing with MFI and it just seemed like bad luck that IVF with ICSI wasn't working. If you haven't already, I'd consider another opinion. Maybe it's just a matter of tweaking your protocol. Best of luck moving forward.
beta#1 3/21 (14dp3dt)=413, beta#2 3/23 (16dp3dt)=785, u/s 4/11
EDD 11/25/12
**SAIFW**
I'm so sorry you are dealing with this. We are also going through the same situation. I agree with you, I would prefer DE to DS (for your same reasoning) DH's uro suggested the fragmentation testing, we agreed but a few days later we decided that this just wasn't for us right now. We are trying to decide what we would do with the information.
These decisions are so difficult to make. I found it to be especially hard to try to make these decisions without my RE's guidance. He was kinda like we could try IVF w/ DS, or IVF with DE or another cycle without donors and a different protocol, but couldn't say this couldn't all happen all over again...I was like, seriously?! you expect ME and DH to try to navigate through this...aren't you the one with the MD initials?! omg...I know it's not his fault, we are dealing w/ male and female factors, but if he doesn't know how to help us, how are we supposed to figure it out?
I truly understand how awful this is, I hope you are taking care of yourselves-
Me (32) DOR, elevated NK Cells/ 2 copies of MTHFR mutation/ MH (35) azoo/high DFI (TTC#1 since 2009)
IVFs#1-4: (4/10-2/12) all BFN
Surprise Bfp (9/11) - c/p
DS IUI#1-2 (9/12, 10/12) - BFN
DS IVF: (11/12) - BFN
DE/DS IVF#1: (10/13) - 2 day 3 embies transferred-BFFN
FET of 2 day 6 blasts: (12/13) - c/p
DE/DS IVF #2: (4/14) - 1 day 5 blast transferred...BFFN...again.
FET 5/14: 1 day 5 hatching blast transferred...another BFFN
Repeat SHG 6/14-normal / Endometrial Receptivity Array biopsy 7/14-Receptive Uterus
New RE, additional testing reveals elevated NK Cells
FET of 1 day 5 blast (RE recommends transferring 1 due to elevated NK cells) with lovenox, steroids & intralipids in October