Trouble TTC

Next Steps - Protocol after failed cycle

Hey ladies,

I had my beta yesterday after IUI #2 and it was negative (as expected.)  But, what happened next was really disappointing.  The nurse said "You can just do another clomid cycle if you want."  I said that I'd really like to have a conversation with my doctor because I'd like to talk about getting more aggressive as I was disapointed in my response to this last Clomid cycle.  It was like pulling teeth to get an appointment this week. 

So, question 1:  Does your RE automatically schedule a consult after a failed cycle?  (Seems to me that should be protocol). 

And question 2:  Am I unreasonable that after 3 cycles of Clomid (1 successful, ended in m/c) I'm ready to add an FSH to the mix?  With 100mgs of Clomid I had 1 no response cycle, and 1 with only 1 follicle.  The 2 cycles I ovulated, it wasn't until CD20, which I feel is late.  Any suggestions would be awesome.  Thanks!

After 22 months TTC and the loss of our identical twins at 10w6d, we're excited about our rainbow baby!
Stick, baby, Stick!
Beta #1 (12dpo): 38.3; Beta #2 (15dpo): 202.7
Baby Girl born 1/17/13

Re: Next Steps - Protocol after failed cycle

  • EagsEags member
    My RE has always had me come back in to discuss how the cycle went & decide how we want to proceed. I don't know about getting more aggressive, I responded fine each time (1-3 follies, Oing between CD 12-20).
    6th cycle of meds/iui combos = BFP!! - EDD 1/21/13 <3
    Born via emergency c-section - 8lb, 19.75 in, 100% stubborn BFP Chart
    Baby Birthday Ticker Ticker
    8 cycles of unmedicated trying = BFP!! - EDD 1/10/18  <3
    BabyFetus Ticker
    *Waiting for Baby Eags 2.0*;
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  • I don't think you are unreasonable at all after 3 cycles of Clomid, that would be the exact point I would start asking for something different too.  Not sure what the next step would be for you, but hopefully they will change it up for you.  Good luck.
    TTC #1 Since May 2011 ~ Everyone Welcome
    Me (34): DOR d/t chemo/radiation, Immature Endometrial Lining, Hypothyroidism
    DH (35): MFI d/t testicular torsion and removal, Low T, Oligospermia, Anti-Sperm Antibodies, Currently on T supplements
    Sept '11-April '13 ~  Testing, failed multiple MFI treatments, saving & TONS of praying
    January 2014 ~ IVF/ICSI & PGS ~ no response to stims ~ converted to IUI ~ BFN
    February 2014 ~ On to donor embyros ~ 5 blasts!!! 
    March 2014 ~ FET #1 ~ Transferred 2 blasts ~ BFN
    July 2014 ~ Kliman's mock cycle with endometrial function test
    Sample too small for EFT, HE slide showed immature cells
    New protocol planned, saving for another biopsy for EFT
    January 2015 ~ Considering adoption options
    April 2015 ~ Privately arranged adoption of planned pregnancy
    DD#1 ~ Lillyana Violet Marie born 6/15/16, Finalized adoption 12/20/16
    July 13, 2018 ~ BFP....WTF?!?!
    7/16 Beta #1 ~ 466...7/18 Beta #2 ~ 1,077...7/23 Beta #3 ~ 5,291
    7/23 US #1 ~ 1 gestational sac seen and yolk sac
    7/30 US #2 and 1st OB appt ~ 1 perfectly round gestational sac, 1 perfect yolk sac and 1 teeny tiny heart beat seen!!!
    Lilypie Maternity tickers


  • My RE doesn't automatically schedule a consult pretty much ever as far as I can tell. I'd have to request it.  We switched from clomid to femara after a few conversations when I caught my primary RE during monitoring.  3 cycles is a normal time frame to think about switching if they were all BFN, but since you had a BFP I also dont' think it's unreasonable to continue for a few more cycles.  Femara has been great for me and I'm glad we made that switch, but personally I'm really hesitant to move to injectibles.  There is a lot of opinion involved in IF treatment.  If you want a more aggressive plan make an appointment and advocate for yourself.
    TTC with PCOS since July 2011.
    IVF Oct/Nov 2012
    Beta #1 = 77, Beta #2 = 190, Beta #3 = 1044
    Cautiously optimistic.
  • My RE does not automatically schedule appointments after a failed cycle. But his plan for me was try femara for 3 cycles and then if not KU re evaluate.  So if after 3 cycles I was not KU then yes i would have a consultation to discuss getting more aggressive.  As far as your second question, I feel like I've heard that several other RE's also go in "3s". If 3 of clomid hasn't worked then its time to change. That may mean femara or it may mean injects etc. But you are reasonable in wanting to change clomid and try something else. Then again since you got a BFP on this protocol and only had 1 BFN following it may not be unreasonable to try it again once or twice.  Sorry about your BFN and GL
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