Infertility

Follistim Question

Hello Ladies - Happy Friday!!!

I have a question that I hope some of you can help me with. I start Follistim tomorrow evening. Right now, and for the last year, my Follistim has been in the crisper drawer in my refrigerator. It was a generous donation. I know Follistim needs to be refrigerated long term but not short-term.

Did you keep it in the refrigerator while stimming or at room temperature? Should I take it out tonight and let it warm up to room temperature and then keep it out while on stims? Or should it be injected cold?

I am pretty sure it doesn't matter and either way is fine, but I wanted to know what YOU did with yours.

Single Mother by Choice. Life didn't work out the way I planned so I did it on my own. IUI #s 1-3, unmedicated = BFN, IUI #s 4-6, 50mg Clomid, Ovidrel = BFN IVF #1: 23R, 20M, 17F. 5 day transfer 2 blasts. 2 Snowbabies BFP 6dp5dt, Beta #1 7dp5dt = 58, Beta #2 9dp5dt = 114, Beta #3 10dp5dt = 187 1st Ultrasound = 5/3, not much to see yet. 2nd Ultrasound = 5/17, TWINS!!! Hospital Bed Rest at 32 weeks due to pre-ecclampsia and severe edema. Audrey Grace, 5lbs9oz, & Lydia Louise, 6lbs, born via emergency c-section on 12/6/12 at 36w1d My IVF Journey

Re: Follistim Question

  • I am on day 10 of Follistim.

    I am keeping in the drawer in the fridge. I was told to only take out as you are about to use and there is no issues (pain etc) injecting it cold me for.

    GL! It is an easy one to inject and the pen makes is so much easier than mixing meds like menopur.

    Multiple ectopics, 2 failed IVF's
    IVF #1: Did not get to ET, embies all failed PGD (major chromosomal defects)
    IVF #2: We have 2 chromosomally perfect embies as a result of PGD (Boy/Girl) 1 failed the thaw (Girl) Transferred 1, yet ended as a c/p
    Thought it was the end of our TTC Journey 6/20/2012
    SHOCK BFP 9/28/2012: IT'S A BOY! and everything is normal !!!!!!

    Little A born 38w 2d on 05/23/13 and is a true miracle for this IF Vet!
     

    image              

     


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  • Once it is loaded into the pen I keep it at room temperature.  I actually kept it in my purse in case I was out and about at inject time.  It was really convenient.

    TTC since 2010

    lots of IUIs and 1 IVF all BFNs

    FET currently on hold

    photo guiness-1.jpg

  • My Gonal-F (same stuff) doesn't hurt even though I inject it cold.
  • kmc84kmc84 member
    I kept mine at room temp (pen) once I started stimmimg. Other than that it sat in the fridge!
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    TTC# 1 since 5/10
    Me:34 Type 1 Diabetes, Ankylosing Spondylitis, Hypothyroid DH:35 Perfect
    DX: Unexplained IF
    Many IUI's with various meds all BFFN
    IVF #1 11/11 canceled due to OHSS
    IVF #2 Feb/March 2012 ET of 2 on day 3 4/7 BFP! 5/1 u/s blighted ovum
    IVF #3 July 2012 ET of 3 on day 3 7/24 BFP!
    Healthy baby girl born at 36w4d on 3/9/13

    Baby Birthday Ticker Ticker
    TTC #2
    IVF #4 May/June 2014 ER 6/4 18R 8M 8F ET 6/9 1 blast, 2 frosties
    Beta 6/18 BFFN

    FET of 2 blasts 7/24...BFP!
    Healthy baby girl born at 36w3d on 3/17/15

    TTC#3
    IVF #5 June 2018- PGS planned, no surviving embryos
    IVF #6 August 2018- ET of 2 on day 3 - Chemical pregnancy
    IVF #7 August 2019-....?
  • imagekmc84:
    I kept mine at room temp (pen) once I started stimmimg. Other than that it sat in the fridge!

     

    This.. My much prefer room temp injects and my nurse suggested this. 

    TTC since June 2011
    DH diagnosed with Testicular Cancer 8/2010
    Low sperm count. Only option IVF with ICSI
    Starting First cycle Jan/Feb 2012- Canceled due to not responding to BCP and/or Lupron
    IVF 1.2- stims March 14, ER March 24, 16 R 10F 6 made it to blast
    ET March 29- transferred two blasts, 4A and 4BA, froze 4
    Positive HPT 9dp5dt Beta 1- 385 11dp5dt
    u/s April 25- one healthy heartbeat
    EDD 12/12/12>


    image
  • I've done it both ways. Initially I kept putting it back in the fridge but then by IVF#2, I said, why am I putting it back in?  I always took it out of the fridge for an hour or so before injecting to "warm" up so now I just leave it out when cycling.

    TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
    DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
    5 IUI's: 2/11 to 6/11 and 1/12= BFN
    OE IVF#1-4 8/11-6/12= all BFN
    DE IVF#1 11/12 bad embryos= BFN
    DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
    CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
    DE IVF #3 1/14  ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d

    DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
    First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!

    K & K born 11/21/14 at 38wks 4 days

    imageimage

    SAIF/PAIF Welcome


    http://waitingforraintostop.wordpress.com

  • I took it out of the fridge about 30 minutes prior to injecting it.... it really didn't take that long to bring it to room temperature.  After I loaded it in the pen, I would just put the pen back in the drawer I kept the rest of my drugs and drug accessories!

    just an fyi in case you didn't know they do put extra in the vials... I got about 425 out of a 300 iu vial. 

    It's easy, you'll do fine!

    Good Luck!!

    Warning No formatter is installed for the format bbhtml
  • I take mine right out of the fridge and take it. 
    ME- 35    DH- 40
    TTC #1 
    IVF#1 w ICSI- 4/20/11 ER, 6 Eggs, 4 Fertilized, 4/25/11 5 day ET, 2 blasts- 5/4- Beta= BFN- No Frosties 

    IVF #2 w ICSI-6/21/11 ER, 4 Eggs, 2 Fertilized, 6/24/11 3 day ET 2 embryos- Beta 7/5/11- BFN- No frosties.
    NEW RE
    IUI #1- started 50ius of follistim 1/25, IUI 2/3/12 - BFN
    AMH-0.73- DOR 2/2012

    IUI #2- 3/17/12 started 200ius of Follistim , 3/24/12 added ganirelix, 225ius Follistim and 75ius of repronex, IUI- 3/30/12, Beta April 13, 2012-BFN

    Appointment with Dr. Schoolcraft at CCRM July 18, 2012
    WAITING ON A MIRACLE AT THIS POINT
    AMH tested again 1/2013- 1.4!!!!
    IUI #3- 1/14/13 started 200ius of Follistim, 1/20/13 added menopur and ganirelix, IUI 1/25/13. Positive HPT 2/6/13- Beta #1- 193- BFP!!! 2/8/13-Beta#2-426.6
    2/26 ultrasound #1- TWINS!
    Delivered a healthy beautiful baby boy on 10/17/13 10ls. 2 ounces

    TTC #2 
    AMH .75 VERY POOR RESPONDER
    IUI #4 cancelled due to only one egg responding 
    IUI#5 cancelled on CD 10,  (3) follicules were still very small even on 300 IU's of Follistim. Also found fluid in my uterus from C-section scar
    BFP- 8/9/15 
    Beta #1 8/10/15 13DPO-   9.2 (fingers crossed this sticks)
    Beta #2 8/12/15 15DPO   39- progesterone 18 
    Beta #3 8/14/15    111- progesterone 17.5
    Ultrasound August 31- 


    PAIF or SAIF Welcome


    image



  • I always kept mine in the fridge, except for the few minutes it took to do the shot each night.  I never had any issues with Follistim stinging or anything.

    Good luck!!!!

    IVF #3 = Feb 2012
    beta#1 3/21 (14dp3dt)=413, beta#2 3/23 (16dp3dt)=785, u/s 4/11
    EDD 11/25/12
    **SAIFW** Baby Birthday Ticker Ticker
  • i wanna say directions say take it out of fridge about 15 minutes or so before you do injection to let it reach room temp..  i was always overly cautious so kept it in fridge the rest of the time... so dang expensive!
    TTC since 10/2010; 3 rounds of clomid 2011- BFNs; IUI #1: 6/2012 BFN; IUI #2: 10/2012 BFP, lost our little one around 6 weeks; IUI #3: 3/2012 BFP, Beta #1 13dpo: 464, Beta #2 18dpo: 3,727. U/s #1:5 sacs, 4 heartbeats! U/s 4/26: 5 heartbeats! BabyFruit Ticker
  • Thanks for all the advice. 

    It's funny, I have an event tomorrow at lunch time and then I am going to some friend's house afterwards. I might not be home before I have to inject so I need to take it with me when I leave in the morning. This is what sparked my curiosity on what to do with it.

    I think I will load it in the pen in the morning before I leave and keep it at room temperature until it's empty. It's a 900 cartridge so it will last the first 4 days of my stims. 

    Single Mother by Choice. Life didn't work out the way I planned so I did it on my own. IUI #s 1-3, unmedicated = BFN, IUI #s 4-6, 50mg Clomid, Ovidrel = BFN IVF #1: 23R, 20M, 17F. 5 day transfer 2 blasts. 2 Snowbabies BFP 6dp5dt, Beta #1 7dp5dt = 58, Beta #2 9dp5dt = 114, Beta #3 10dp5dt = 187 1st Ultrasound = 5/3, not much to see yet. 2nd Ultrasound = 5/17, TWINS!!! Hospital Bed Rest at 32 weeks due to pre-ecclampsia and severe edema. Audrey Grace, 5lbs9oz, & Lydia Louise, 6lbs, born via emergency c-section on 12/6/12 at 36w1d My IVF Journey
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