Question and update (long)

adoruhbul

Hey girls!

I've been mostly lurking since the last m/c and finally ready to get back to posting and not just lurking, so I thought I'd post an update and ask a quick question for those reading this.

I had my repeated loss testing done except for the karyotype which I'm still waiting on, there seems to be an issue with my NK cells and a minor thrombophilia.  We also gave in the embryo for biopsy and the test came back normal, both my RE and the hosptalist OB believe this last m/c was a result of a subchorionic hematoma aka SCH.  Most of the time these hematomas are common and do not cause any problems aside from the very scary spotting, however mine grew to the same size as my uterus and literally made the gestational sac collapse, which then caused a m/c.

It really hurts knowing that for once we had a healthy baby and it died because my body once again failed me.  We finally came to the conclusion we would try two more times before throwing in the towel for good.  By two times, we mean two more failed pregnancies not failed cycles.  

We went to my RE and basically said we would proceed exactly the same as last time just add in Lovenox.  When it actually came time to cycle a week ago, he changed his mind and decided to get much more aggressive.  As of the latest pregnancy, we've been successful 3 out of 3 cycles, which is honestly insane since TI never worked no matter how many cycles actually went by (I have a severely retroverted uterus--which is the only explanation anyone has come up with).  So when my RE mentioned his new aggressive plan I was a bit hesitant at first, but we decided that we were at the point we'd do absolutely anything to bring home a baby.

The plan was to increase my Follistim dose from 200IU for 5 days then 150IU for 6 days to 300IU for 6 days and 200IU for 5 days.  Last 2 cycles I only had one follie when it came to the IUI and he was hoping for at least 4 or 5 this time.  We have been stemming for 11 days now and still not even close to triggering.  I have a whopping 10 follies all about the same size, which is around 10-12mm.  The plan is to trigger on Thursday for a Saturday IUI.  After the IUI I will be continuing with dexamethasone, Delestrogen, PIO, baby aspirin, Lovenox, and Intralipids.

 We are pretty scared to be going forward with what will probably be 8 follies, but he very optimistic that this will be what we need.  With the first two m/c's being from a combination between genetic problems and a blood clotting problem he thinks we probably are dealing with a chromosomal problem and having so many eggs will give us a greater chance of having a normal embryo among them.  Here is to hoping this finally works!

As for my question if you don't mind... Since we increased the dose of Follistim, it has been taking much longer to stim then usual.  I assumed that the increased dose would mean a sooner IUI but it's becoming quite the opposite, has this happened to anyone?  I will be stimming for about 6 more days then I usually do.

 Thanks for reading!  Wishing you all good luck this cycle, glad to be back to posting and out of lurkdom! 

kelnyc

*sig warning*

I am sorry sorry for all you've gad to go through, and I certainly don't want to second-guess your doctor, but it alarms me that he wants to do an IUI with so many follies... especially considering you've been successful with just one previously. What happens if you end up with 8 succesfully fertilized eggs? I think it's irresponsible to be so aggressive when there doesn't seem to be a need for it. If it scares you and makes you nervous, I'd say there's probably a good reason for that. 

adoruhbul

kelnyc:

*sig warning*

I am sorry sorry for all you've gad to go through, and I certainly don't want to second-guess your doctor, but it alarms me that he wants to do an IUI with so many follies... especially considering you've been successful with just one previously. What happens if you end up with 8 succesfully fertilized eggs? I think it's irresponsible to be so aggressive when there doesn't seem to be a need for it. If it scares you and makes you nervous, I'd say there's probably a good reason for that. 

I definitely respect your opinion and if it weren't for the 3 losses I'd probably agree, but at this point we are prepared to take the gamble.  The doctor has been very conservative up to this point (we've seen him for almost 8 months now/6 cycles), so I feel more inclined to trust him.  He did give us the selective reduction speech however and we are prepared to handle the outcome regardless of what it is.  He says the chance of them all implanting are very low figuring we have a chromosomal issue and most will probably not make it past the 6 week mark as a result.  I appreciate your concern and I will rebring it up next appointment before the IUI. 

kelnyc

adoruhbul:

kelnyc:

*sig warning*

I am sorry sorry for all you've gad to go through, and I certainly don't want to second-guess your doctor, but it alarms me that he wants to do an IUI with so many follies... especially considering you've been successful with just one previously. What happens if you end up with 8 succesfully fertilized eggs? I think it's irresponsible to be so aggressive when there doesn't seem to be a need for it. If it scares you and makes you nervous, I'd say there's probably a good reason for that. 

I definitely respect your opinion and if it weren't for the 3 losses I'd probably agree, but at this point we are prepared to take the gamble.  The doctor has been very conservative up to this point (we've seen him for almost 8 months now/6 cycles), so I feel more inclined to trust him.  He did give us the selective reduction speech however and we are prepared to handle the outcome regardless of what it is.  He says the chance of them all implanting are very low figuring we have a chromosomal issue and most will probably not make it past the 6 week mark as a result.  I appreciate your concern and I will rebring it up next appointment before the IUI. 

I'm glad you've had that talk, and I do appreciate that given your issues, the odds of having them all fertilize and stick are lower. I would just hate for your desire to have this work lead to a situation where you have even half take and then have to carry them for the first trimester and have to reduce. It's not a position I would envy, especially after watching a friend go through it. It's not easy. But, if you are comfortable with you doctor's advice and whatever may lie ahead, then I wish you all the luck! 

adoruhbul

kelnyc:

adoruhbul:

kelnyc:

*sig warning*

I am sorry sorry for all you've gad to go through, and I certainly don't want to second-guess your doctor, but it alarms me that he wants to do an IUI with so many follies... especially considering you've been successful with just one previously. What happens if you end up with 8 succesfully fertilized eggs? I think it's irresponsible to be so aggressive when there doesn't seem to be a need for it. If it scares you and makes you nervous, I'd say there's probably a good reason for that. 

I definitely respect your opinion and if it weren't for the 3 losses I'd probably agree, but at this point we are prepared to take the gamble.  The doctor has been very conservative up to this point (we've seen him for almost 8 months now/6 cycles), so I feel more inclined to trust him.  He did give us the selective reduction speech however and we are prepared to handle the outcome regardless of what it is.  He says the chance of them all implanting are very low figuring we have a chromosomal issue and most will probably not make it past the 6 week mark as a result.  I appreciate your concern and I will rebring it up next appointment before the IUI. 

I'm glad you've had that talk, and I do appreciate that given your issues, the odds of having them all fertilize and stick are lower. I would just hate for your desire to have this work lead to a situation where you have even half take and then have to carry them for the first trimester and have to reduce. It's not a position I would envy, especially after watching a friend go through it. It's not easy. But, if you are comfortable with you doctor's advice and whatever may lie ahead, then I wish you all the luck! 

Any chance your friend is available to speak to?  It's so hard to find info from people who've gone through it online.  I know it's one thing to think you can do it, but a whole other thing to actually go through it.  I'd love to know her story and how she coped if she is available online.  Thanks again for the well wishes, definitely will keep that all in mind. 

kelnyc

adoruhbul:

kelnyc:

adoruhbul:

kelnyc:

*sig warning*

I am sorry sorry for all you've gad to go through, and I certainly don't want to second-guess your doctor, but it alarms me that he wants to do an IUI with so many follies... especially considering you've been successful with just one previously. What happens if you end up with 8 succesfully fertilized eggs? I think it's irresponsible to be so aggressive when there doesn't seem to be a need for it. If it scares you and makes you nervous, I'd say there's probably a good reason for that. 

I definitely respect your opinion and if it weren't for the 3 losses I'd probably agree, but at this point we are prepared to take the gamble.  The doctor has been very conservative up to this point (we've seen him for almost 8 months now/6 cycles), so I feel more inclined to trust him.  He did give us the selective reduction speech however and we are prepared to handle the outcome regardless of what it is.  He says the chance of them all implanting are very low figuring we have a chromosomal issue and most will probably not make it past the 6 week mark as a result.  I appreciate your concern and I will rebring it up next appointment before the IUI. 

I'm glad you've had that talk, and I do appreciate that given your issues, the odds of having them all fertilize and stick are lower. I would just hate for your desire to have this work lead to a situation where you have even half take and then have to carry them for the first trimester and have to reduce. It's not a position I would envy, especially after watching a friend go through it. It's not easy. But, if you are comfortable with you doctor's advice and whatever may lie ahead, then I wish you all the luck! 

Any chance your friend is available to speak to?  It's so hard to find info from people who've gone through it online.  I know it's one thing to think you can do it, but a whole other thing to actually go through it.  I'd love to know her story and how she coped if she is available online.  Thanks again for the well wishes, definitely will keep that all in mind. 

I'll see if she minds if I give your her email.