TTC after 35

PIO Shots-Nervous!

Hi All-

DH and I are going to try for #2 using our frostbabies left over from IVF.  With IVF #1, I was given progesterone in a tablet form.  However, with the FET, my dr wants me to use PIO and estrace (I think) shots.  Both of these meds look like they're in oil, and I've never done this super deep shots with oil.  I'm really nervous b/c I've heard they are REALLY painful.  Any tips to make these shots less painful or are they just going to hurt like heck and I have to deal w/ it? 

Re: PIO Shots-Nervous!

  • Ice the area first, heat afterwards.  I gave myself PIO and didn't find them to be as terrible as I'd heard.  Although, by Beta both butt cheeks were feeling a bit sore.

    TTC since 10/09 Me-43 DH-44 RE and testing 10/10-11/10, Recommending IVF 1/11 New RE AMA and DOR-DH low motility IVF #1.1 cancelled 3/11 due to poor response IVF #1.2 May 2011, one perfect 8-cell embryo, 3dt-BFN, IVF #2.1 Converted to IUI d/t poor response. New RE 9/2011. IVF 2.2 completed using HGH,EPP,DHEA, Q-10 and accupuncture. Transferred one 8-cell, grade one embryo on 10/19. BFP 10/31/11 Chemical pregancy on 11/2/11. Started stims for IVF #3, our final try, on 12-2-11. ET on 12/18. Transferred 3 Grade A embryos-BFFN Planning DE IVF, late March/early April- Donors ER expected to be 4/2-4/4. PAIF/SAIF welcome
  • The anxiety was worse than the shots for me. They're not fun, but they're not that bad.

    Warm the vials up with body heat (I always stuck in my cleavage or had DH hold onto the vial for a few minutes) to help make the oil less viscous. And, rub the injection area afterwards to help disperse the oil in the muscle. I also walked and/or did squats afterwards to help disperse. Good luck!

    TTC #1 since June 2010
    Me: 36, DH: 42
    Dx: DOR and MFI

    DH: low count + very low motility; hormones all normal; Sperm DNA Frag. test = poor to fair; male karyotyping normal
    Me: FSH 13.4 + AMH 0.26 + hypothyroidism; Scratch the hypothyrodism (?); Blood clotting and immune panel all negative; endometrial biopsy normal

    IVF #1 (MDLF - Jul/Aug 2011): BFN (9R, 5M, 3F with ICSI, 3dt of 1 10-cell grade 2, no frosties)
    IVF #2 (EP-antagonist - Sep/Oct 2011): BFN (6R, 4M, 3F w/ ICSI, 3dt of 1 6-cell, 1 7-cell, grade 4s, no frosties)
    DE IVF #1 (shared cycle - June 2012): c/p (6R, 6F w/ICSI, 3dt 1 8-cell grade A- and 1 7-cell grade A-; no frosties)
    DE IVF #2 (shared cycle with new donor - Nov/Dec/ 2012): - BFP!!!!! 12/14/12. U/S on 12/27 shows twins!!!!!

    SAIFW/PAIFW
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  • What Happywife and Mtlaurel said but I'd like to add, that I didn't need the icing or anything else special. The pain wasn't that bad and much of the time the anticipation was worse than the event. 

    Deep calming breaths (exhale as the needle goes in) and confidence helped a lot.

  • The first couple for me were tough but by the 8th day I seem to be handling them much better. Not a fan of the side effects. I just feel blah and not myself. Cranky and crabby as well which my DH is catching most of that! My hips are sore and I am sure will continue to get more sore but then I knew that going in. Good luck to you.
    TTC #1 since 2/10 Me 38 FSH 12.9 & AMH 0.16 DH 47, low sperm count due to meds. 07/11 We have sperm! 28 million, 70% motility, morphology 1% normal. 08/14/11 1st IUI unmedicated BFN. 09/11/11 2nd IUI w/ Femara + trigger BFN 10/14/11 trigger & Final IUI 10/16/11 BFN 10/21/11 Started acupuncture and loving it! 01/21 ET one embryo 6 cell grade C. Beta 02/02. BFN. Taking a much needed break. image
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