Pregnant after IF

If you transferred 2 embryos

Did your RE recommend transferring 2 or did s/he do it reluctantly?  Mine strongly advised us to only transfer 1 and gave us an hour long speech about the complications with twins.  He really made us question whether or not we were making the right decision.  All along I hoped for twins because I am 43 and thought we could have a whole family in one go.  But he really made us think twice.

In the end, the day of the transfer, we convinced him that we were prepared for whatever happens and he let us transfer 2.  I won't know how many are in there for a few more weeks but I was just curious if anyone else is concerned about twins or are most people hoping for them?  We are still very much hoping for them, but if anything goes wrong I will be guilt ridden about the choice we made.

4/08 BFP resulted in m/c
8/08 BFP resulted in m/c
3/09 Polyp removed and dx MTHFR (both copies)
6 Clomid cycles, all BFN
5/09 IUI#1 with Clomid=BFN
6/09 IUI#2 with Clomid=BFN
8/09 IUI#3 with Clomid=BFN
IVF#1 = BFN
IVF#2 = BFN
IVF#3 ET 2 Grade A blasts 11/16/11
Beta #1: 485
Beta #2: 2,495
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Re: If you transferred 2 embryos

  • I was fully expecting my RE to be set on one embryo because before we even made it to ER, the other RE in the practice gave us a talk about my being an excellent candidate for SET. 

    The day of ET, RE called and the first thing he said was, "So we're transferring two today, right?"  I think that put me more at ease than the Valium. 

    My first u/s isn't for a few more days, so I'm not sure how many stuck.  Good luck to you! 

    Twin boys due 7/25/12
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  • Ours recommended 2-3 based on our age. We transferred two because that was what we were comfortable with. We would've been okay with twins, but we didn't hope for them. They can make pregnancy much harder and riskier and that just isn't something we were wishing for. 

    Good luck! 

    TTC since 2006
    Me: 36 DH: 40
    DH dx azoospermia My dx: RA & AMA
    d-IUI's--6/10, 7/13 & 8/4: all BFN
    d-IVF#1--Lupron/Menopur/Bravelle/Novarel; mini-dose protocol
    ER: 10/25--18R; 14F; ET: 10/28--3dt of 2 embies; 3 blasts frozen
    + HPT 11/4; Beta #1--14dp3dt: 441; Beta #2--21dp3dt: 9298
    One beautiful jelly bean growing! Saw h/b on 11/28 and 12/5!!!
    P/SAIF welcome
    <a href="http://s22.photobucket.com/albums/b315/mandalinn/?action=view
  • The day of my transfer my RE told me what a great candidate I was for an SET and talked to me about how the ASRM guidelines for someone my age etc were just one embryo.  My husband and I had only talked about 2...and at this point the embryologist had already shown me the photo of the 2 embryos she wanted to transfer and I was already emotionally attached to them. Despite feeling pressured to go with one, I stood my ground and asked that 2 be transferred.

     Before I left I had to sign something acknowledging that I had chosen to not adhere to the ASRM guidelines - which sort of irked me.

    My first u/s is next week and we are very anxious.  We are well aware of the risks associated with multiples (I'm an aunt to twins) but I'd by lying if I said I'm not hoping that both embryos stuck.

    ETA: I'm 34

    TTC #1 since 12/2009 HSG -all normal SA - perfect Clomid 100 = no response Clomid 150 + Ovidrel + IUI = BFN Clomid 150 = no response Clomid 100 + 75 Follistim + Ovidrel + IUI = BFN Clomid 100 + 75 Follistim + Ovidrel + IUI = BFN ---
    First IVF: Started BCP 10/4, Mock Transfer 10/12, Trigger 11/1, ER 11/3 (32 retrieved, 16 fertilized) - ET 11/8 (transferred two perfect day 5 blasts, 5 more embies frozen). BFP @4dp5dt Beta #1 11/17 = 145! Beta #2 = 996! Pregnant with twins! Lost baby B @8weeks. Perfect baby girl born in July. All of our dreams have come true!
  • Our RE gave us the guidelines, and we transferred two each time. We never considered more (or one) and he didn't give us a hard time. I'm surprised he gave you a hard time given you are AMA and have past failed IVFs, it is certainly within reason to transfer two, unless you have a health problem that would make twins a bad idea. I was 34 for each of our transfers.

    I can't say we were hoping for twins, but obviously we were very open to them since we did two. Some are problem free, but let me tell you a twin pg is no joke. I have no idea whether I would have had the complications I have had if it were a single pg (we nearly lost our twins @21w from IC and I'm going on 4 mos of bed rest) but it certainly ups your risks of all sorts of things, besides the fact that they almost always come early, putting them at some disadvantage potentially from a development perspective. Now that we've made it this far, we are very thankful we have two that seem to be healthy, as I think we'd likely be done even if we only had one, and we've always wanted two. Best of luck!

    TTK 9/06 / TTC 10/08 / Twins 12/11 / Life Blog
    5 REs + 3 surgical hysteroscopies for septum/lap + 3 failed IUIs
    IVF w/ICSI/AH & acu = BFP!, unexplained spontaneous m/c @ 8w2d (our little girl),
    FET w/acu = BFP!, B/G twins!, lost MP @19w, dx w/funneling cervix @20w,
    twins nearly lost to IC @21w, saved by rescue cerclage, 17P & 16w of bedrest
    Our twins born @36w4d via CS when A came foot first

    Thankful for every day

    Baby Birthday Ticker Ticker

  • Our RE recommended 2 and was willing to transfer 3 if we really wanted to. We stuck with transferring 2 all 4 transfers.
    Married 08.06
    Started TTC 05.08
    Me: Stage II endo, borderline high FSH
    DH: perfect
    1 lap, 5 IUIs = 4 BFNs and 1 c/p
    2 IVFs, 2 FETs = 1 BFN, 1 c/p, 1 ectopic and finally a sticky BFP in May 2011!

    Baby Birthday Ticker Ticker

    1 FET in Aug 2013 = BFP! 

    Pregnancy Ticker
  • Prior to knowing the grades and even how many we had, we talked with our RE who told us that 1-2 was the guidelines for our particular case. He gave a pretty balanced picture of the risks/rewards of putting back two versus one and we knew we would likely do two.

    When we found out the grades (one excellent, one goodish - don't remember exactly now) and that only two had actually made it, it was a no-brainer. At that point he actually recommended putting both back as well.    

    2 IVFs & 1 FET. Welcome home baby girl!
  • imagekthappy76:
    I'm surprised he gave you a hard time given you are AMA and have past failed IVFs, It is certainly within reason to transfer two, unless you have a health problem that would make twins a bad idea. I was 34 for each of our transfers.

    I should have mentioned that I used DE this time so the previous cycles really didn't predict much this time around.  We had 24-year-old beautiful Grade A blasts this time so he was pretty sure they had a good chance of sticking.  I don't think there's any reason to think I can't carry twins though.  My uterus seems to still be in good shape at least!

    4/08 BFP resulted in m/c
    8/08 BFP resulted in m/c
    3/09 Polyp removed and dx MTHFR (both copies)
    6 Clomid cycles, all BFN
    5/09 IUI#1 with Clomid=BFN
    6/09 IUI#2 with Clomid=BFN
    8/09 IUI#3 with Clomid=BFN
    IVF#1 = BFN
    IVF#2 = BFN
    IVF#3 ET 2 Grade A blasts 11/16/11
    Beta #1: 485
    Beta #2: 2,495
    Lilypie First Birthday tickersimage
    imageimageimage
  • well we did clomid but would have transfered two and RE would have been fine with it, esp. bc of my DOR.  (also, im 32)

    but i got them from two mature follicles on clomid and no, i wasnt expecting that at all.  not with all of my dire DOR stats.  we already have a toddler and twins was not something we were anticipating or necessarily hoping for...simply because of "all the complications" that go along with twin pregnancies.  it's like you are never "safe" with them....at least my OBs never let me relax bc this and that could happen.  i understand the wanting of the instant family...but twins just scare the crap out of me bc of all the possible complications, possible bed rest, babies coming early, stuff going wrong after they are born, etc.

    that being said im almost 20 weeks and i guess ive had an "easy" twin pregnancy, although ive noticed the difference regarding being pregnant with 2 vs. 1.  im only up 3 pounds from my pre-preg weight but i feel huge.  i can go to the gym, chase around my toddler, but i get tired/hungry more quickly and have more aches and pains.  my cervical length last week was good - 5mm but that can change any time.  it's like i feel like the bedrest is constantly looming.  we'll see what's in store for the future.  i can say that now that they are moving it's pretty surreal to feel both moving on either side of my tummy. 

  • I'm only 34 and at one point we discussed transferring 3 (this was after a failed cycle).  In the end we transferred 2.  My RE never even suggested only 1.  I can't believe that at 43 your RE would suggest a SET.

    Our Journey to Brenden

    IVF #1: 4/11(Follistim/Menopur/Ganirelix) 10 retrieved/8 mature and all 8 fertilized / 2 embies transferred ... nothing to freeze Beta 5/10 = BFN

    IVF Take 2 Long Lupron July 2011

    ER 7/3/11 (our 6th anniversary) - 8 retrieved/7 mature/fert ....ET 7/6/11 - 2 beautiful grade A 8 cell embryos

    Beta 7/18/11 - 149!!! Beta 7/21/11 - 311 Beta 7/28/11 - 2,000 8/5/11 - Empty Sac 8/8/11 - There's a yolk sac and maybe a heartbeat 8/12/11 - Fetal pole, yolk sac, heartbeat 8/18/11 - Baby looks GREAT!
    3 babies waiting on ice


    Lilypie Second Birthday tickers


  • It really depends on your situation and dx.

    I was 31 for all 3 IUIs and all 3 IVFs.  We are unexplained IF.

    I do take my RE's opinion seriously.  Before we even started stimms my RE gave me a whole packet to read about the complications of a twim pregnancy, and how the sucess rate of transfering two is nearly the same as transfering one, only with a greater change of multiples.    

    For my first ET, I somehow made it to a day 6 (yes 6) transfer, and I had 5 grade A blasts to choose from.  My RE suggested SET, and given the cercumstances he gave me a 65% sucess rate.  So I only transfered one.  That IVF resulted in a chemical pregnancy.

    My second IVF, I did a FET.  My RE again suggested one.  So, I again only transfered one perfect 6 day blastocyst.  I think because my first IVF I was "so close" to sucess, I was really afraid to transfer two.  That resulted in a BFN.

    For my third IVF, I told him I wanted to do another fresh (since it was the last one covered by my insurance, and if it failed it would be cheaper to use my frozen ones).  This time I asked if if he thought I was a good canidate to transfer two.  He said yes, given the fact that I've had two failed IVFs.  I also asked if I was a good canidate for Assisted Hatching.  He said yes.  So this time I did two (one perfect blastocyst and a morula) with assisted hatching.  And I finally have a BFP!

    I have my first ultrasound tomorrow (6w1d), so I'll get a head count.  I'm kind of torn.  There is part of me that likes the idea of twins.  But I'm seriously concerned about actually being pregnant with twins.  When we did the transfer I was just hoping for just one of them to stick.  But now after several weeks, I'll be really said to find out that only one stuck. 

    BTW - For every one of my transfers I had to sign a form confirming how many I was transfering (even when it was jsut one).  They are probably required to have you sign that form stating that you went against the guidelines just to cover thier butts.  So they can't be blamed if you transfer 8 and become the next octomom!

     

    My Journey to Motherhood
    Me 36, DH 42
    7.5 years of TTC ... It never gets any easier.


    Baby Girl # 1
    TTC Since January 2009
    Reproductive Endocrinologist diagnosed us "Unexplained Infertility".
    After 3 years . . . 3 IUIs . . . and 3 IVFs . . . our miracle GIRL arrived on August 6, 2012.

    Baby Birthday Ticker Ticker

    Baby Girl # 2
    TTC Since June 2013
    Got pregnant on our own without Fertility Treatments - January 2016!  Thank you snow storm Jonas!
    EDD 10/15/16
    At 20-week anatomy scan found IUGR (Intrauterine Growth Restriction), and very low Amniotic Fluid.  Now, I'm High Risk and have weekly ultrasounds to monitor fluid and growth.  If baby runs out of room or is too growth restricted, they will deliver ASAP.  My current goal is to make it to 28 weeks!   


    Pregnancy Ticker

  • We transferred two at our doctor's recommendation.  He of course said we could definitely transfer just one, as long as we were open to twins.  But from the start he told us that everything he would do would be to get us pregnant with ONE, so in his mind us transferring two gave us the best odds of one sticking...and (so far) it did.
    Mr. & Mrs. UMich! July 2006! :-)
    image
    DX: High FSH/DOR
    It took 44 cycles, just over 3 years, 6 failed IUI's in MI, and 1 round of IVF at CCRM to get our BFP!

    Beta #1 (9dp5dt) = 206, Beta #2 (11dp5dt) = 438
    1st u/s @ 6w5d = 11/11/11 = ONE little bean! HB 120bpm!
    ?Our Baby Boy Born June 26th, 2012?

    Baby Birthday Ticker Ticker
  • It's such a personal decision.  Our first cycle, my RE rec'd two.  One stuck but I miscarried.  For our second cycle, he was willing to transfer whatever we were comfortable (2-3), and we decided on three.  Again, only one stuck, but it divided, so I'm pregnant with identical twins.

    GL!

    MFI and (now) AMA
    IVF 1 April 2011 - Cancelled
    IVF 1.5 July 2011 - MC
    IVF 2 October 2011 - BFP!
    *Identical Twin Boys born June 2012*
    Here we go again...IVF 3 is underway!
  • I transferred 3 knowing we could be at risk for triplets. Granted, they were frozen and one was iffy according to my doctor. To my knowledge, my doctor did not suspect I had crappy eggs at that point, so triplets were not out of the question. I'd honestly be scared of transferring less than 2, but I wanted the best chance possible.
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  • We went with my doctor's recommendation each time.  We did three fresh IVF cycles and transferred 2 perfect blasts the first time + BFN; three blasts (one perfect that was frozen from my first cycle, one pretty good fresh and one poor fresh) = BFN; the third cycle we only had to eggs fertilize properly, so we transferred both embryos on day 2 with assisted hatching and one stuck. 

    It turns out I have implantation issues.  So, I would guess I would get the recommendation to transfer two even if they were DE.  But, I have had issues with carrying a singleton this time around.  So, I would maybe only transfer one next time since carrying two has increased risks.  Good luck!!

    imageimage


    ~SAIF/PAIF/Everyone Welcome~ 

    Me= 37 and DH = 41 

    Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)

    IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN

    IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.

    IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132.  Lil is here!

    TTC#2:  Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.

    IVF #4:  BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN

    IVF #5:  MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN

    IVF #6:  (New RE):  Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN

    FET#1:  BFN

  • Our clinic strongly promotes elective single embryo transfers for first time cycles depending on the patient's medical history.

    They were not happy when my husband and I elected to transfer two embryos (we would have only done one if our fresh transfer hadn't been cancelled).  I am now pregnant with a singleton.

    ETA: I'm 28 and have an endo/tubal diagnosis.

    TTC since August 2009
    June/July 2011 - IVF #1 - Transfer cancelled due to OHSS
    23 perfect embryos. All 23 made it to freezing!
    September/October - FET #1 - October 12th - 2 Grade A embies
    October 20th - BFP??! EDD - July 1, 2012
    Beta #1 = 154, Beta #2 = 352 Beta #3 = 3,800
    U/S #2 - November 14th = 133 bpm! U/S #3 & 4 - November 30th and December 7th = 163 bpm! U/S#5 - January 30th - TEAM PINK!!!
    Baby Sweets born on her due date!
  • He recommended and transferred 2 (it was our 1st donor egg cycle) but I have a history of repeat miscarriages but with my own eggs.  He would do no more than 2 though.  We were ok with 2.  I'm glad we transferred 2 this cycle because we ended up having a vanishing twin with this pg. 

    I have had a lot of complications with this pg (low amniotic fluid diagnosed at 21 weeks and have been on bedrest since.  I'll deliver early; it's anyone's guess as to when.  It depends on how long my placenta holds out).  So I do wonder what would be happening if it were a twin pg in my case.  I think multiples would further complicate things in my situation, but it goes without saying that we were sad that we lost a baby. 

    I will say that maybe there's comfort for us in knowing that we have 16 embies on ice for us from our donor egg cycle for future children. 

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  • I am so glad I asked this question.  Such interesting responses! 
    4/08 BFP resulted in m/c
    8/08 BFP resulted in m/c
    3/09 Polyp removed and dx MTHFR (both copies)
    6 Clomid cycles, all BFN
    5/09 IUI#1 with Clomid=BFN
    6/09 IUI#2 with Clomid=BFN
    8/09 IUI#3 with Clomid=BFN
    IVF#1 = BFN
    IVF#2 = BFN
    IVF#3 ET 2 Grade A blasts 11/16/11
    Beta #1: 485
    Beta #2: 2,495
    Lilypie First Birthday tickersimage
    imageimageimage
  • imagelunatwo:
    I should have mentioned that I used DE this time so the previous cycles really didn't predict much this time around.  We had 24-year-old beautiful Grade A blasts this time so he was pretty sure they had a good chance of sticking.  I don't think there's any reason to think I can't carry twins though.  My uterus seems to still be in good shape at least!

     The condition of your uterus before pregnancy really has no bearing on how you will handle a twin pregnancy. There was no way to tell before I got pregnant that I would have an irritable uterus and go into preterm labor at 26 weeks. I was able to hang on to 34 weeks, but it was HARD. I had other complications as well due to carrying twins and was on bed rest for 12 weeks and in and out of the hospital starting at 16 weeks. So like a PP said a twin pregnancy is no joke.

    My RE's goal was to transfer two. There was never a question as to whether we would transfer more or less, if we had 2 embryos to transfer that was how many we were going to do. My husband and I were open to twins (obviously) I can't say I was hoping for them, we were just hoping for a successful IVF, but I feel blessed that we were lucky enough to have 2 healthy take home babies. That being said, being a MoM is the hardest thing I've ever done. Taking care of two newborns presents challenges everyday that you can't imagine until you are there. Good luck to you! If you do end up pregnant with twins the multiples board was a great resource both for information and support.

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  • With our fresh IVF cycle they advised to only transfer 1. We were very OK with this decision. That ended in C/P.

    We discovered a progesterone deficiency on top of everything else and so we came up with a medicated FET plan that included PIO injections and with the FET, he recommended 2 which surprised me a lot. It took us a while to get on board with that idea but we finally did and don't regret it for 1 second.

    Good luck. :)

    Taking the Scenic Route
    FET: Success! Beta at 14dp5dt: 2427 TWINS!!
  • My RE recommends one, but didn't give us a hard time when we chose to do two. They had lots of info for us prior to transfer regarding the risks, etc. My feeling was that if we transferred two and had twins- great! If we transferred one and didn't get pregnant- I would have always wondered what would have happened if we had only done two. We ended up transferring two and ended up with a singleton. I certainly don't regret transferring two at all.
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  • For our first transfer, which was a day 3 transfer, they recommended we transfer just one since we had one 8-cell with very little fragmentation that stood out as being clearly the best, with several 8-10 cell embryos with some fragmentation. Since it was a day 3 transfer, I didn't feel super confident that the one great-looking embryo was really the best and I thought 1 embryo was a little too conservative. My gut was to go with two (if we had an excellent quality blast, however, I probably would have been fine with transferring 1). After 6 IUIs with the RE always reassuring me that my prognosis was great and pregnancy was just around the corner, I was also feeling sort of jaded and didn't have such confidence that our first IVF would work even though I know I look very good on paper, and of course I was right.

    For our second transfer, which was a FET we transferred 3, but only because all of the embryos were damaged in the freezing/thawing process and also my old clinic had lower success with FETs than with fresh cycles.

    For my third transfer, also frozen, we transferred only one, because of our remaining embryos, only one survived the thaw :(

    For my fourth transfer, which was a fresh cycle with a new clinic, we had blasts for the first time. Only two of the embryos made it to day 5. Neither was 'top quality' according to my RE and he didn't question or second guess my desire to transfer both. I think everyone could agree two was reasonable at this point, since I had already transferred 6 embryos with no success. Still don't know whether we have 1 or 2 baking, but our first u/s is Sunday so we will see what's going on quite soon. And that is our full history of how many embryos we transferred at way too great a length:)

    IUIs #1-3 (1x unmedicated, 2x Clomid) = 2 BFNs, 1 m/c at 7w3d
    IUIs #4-6 (injects) = 3 BFNs
    IVF #1 = BFN
    FET #1 = BFN
    FET #2 = BFN
    IVF #2 = BFP, b/g twins lost at 20w due to partial abruption/PPROM
    IVF #3 = c/p 5w2d
    Long-shot Clomid/Prednisone cycle before next IVF = BFP, our beautiful, healthy girl born 6/26/13!
    ~~
    TTC again March 2014
    FET #3 - May/June 2014
    -
    all embryos arrested before xfer - back to the drawing board...
    IVF #4 - July/August 2014 
    beta 1 (11dp3dt) 220, beta 2 (13dp3dt) 671, beta 3 (19dp3dt) 10762
  • We only transferred one, but at my age (40) my RE said they normally do 3.  We weren't comfortable with that at all, so went with a SET, despite the odds, and luckily it worked out for us.
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