Trouble TTC

Two questions about unmedicated IUI timing?

My RE is having us do our first IUI this cycle, and I?m nervous and anxious! I have not had an HSG quite yet, yet my insurance pays for IUIs through the end of the year, so my RE has a "what could an unmedicated IUI hurt?" point of view. My husband's first and only SA came back not-so-good so we all know it's a long shot.

Regardless, the plan is for me to call their office when I first get a positive OPK and then the IUI will be scheduled for the following day. I will not receive a trigger. I asked the nurse what time the IUIs get scheduled for, and she said it would be up to me to choose morning or afternoon on the day following the surge. The lines on my OPK are getting darker and darker, so I'm pretty sure I'll get my positive later this afternoon/evening based on my observations from previous cycles. I've read that washed sperm can only survive six hours, which obviously means timing is critical.

First question: For those of you familiar with IUIs,  what time of day would you think is most effective for the procedure to be done if you get an positive OPK in the evening? The following morning? Or the following afternoon?

Second question: Has anyone had their husband deliver his sample in the morning (which mine will HAVE to do before work) to then do the IUI later that afternoon? Or does the IUI have to be done immediately after the sample being washed?

I am praying for some kind of a miracle but want to give us the best shot possible. I appreciate your thoughts/suggestions since this is new to me! Thanks in advance!

************ Signature/Ticker Warning ************
Me (32) DH (36) - Finding our way to baby #1
Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
DH: Severe MFI

12/2/11 - IUI #1- BFN 
8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

My ovaries are just for decoration

12/6/12 - Adopted five embryos that had been frozen for over ten years!
2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

6/5/13 - Adopted four new embryos that had been frozen for seven years!
 
9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
9/29/13 - m/c @ 5w1d. :(

11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

Snowflake baby is a girl! 
Our beautiful Snowflake girl arrived on July 22, 2014!   
My embryo adoption blog: Wishing on a Snowflake
 
    image      image 

Re: Two questions about unmedicated IUI timing?

  • I have no experience with unmedicated or OPK IUI's,  but my RE does my IUI 36-40 hours after ovulation.
    http://oi58.tinypic.com/nqv6fk.jpg

    DX: PCOS/Recurrent losses/MTHFR mutation (compound hetero)
    5 hysteroscopies/2 surgical
    3 Inject IUIs = 2 m/c's and 1 BFN
    IVF #1= BFP. m/c at 7w6d. Needed 2 D&C's and scar tissue removal. Mild OHSS
    IVF #2 = BFP. Severe OHSS. 4 Drainings. TWINS!
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  • We've always done IUIs this way medicated or not. There is no way to time it perfectly with ovulation. A positive surge means you'll ovulate in 12 to 48 hours. As long as you get the sperm up there before the egg dies, you're good. With that said, if YH does a morning drop off, the IUI needs to be around noon. Noon dropoff and it will be late afternoon, close to the end of the day. I don't think you can dropoff in the morning and wait until the end of the day to do it.

    Also, you may want to test soon because some offices have a policy about scheduling IUIs before the office closes. For instance, I can't call past 3 to scheule an IUI for the next day, so I would take my OPKs around 1. 

    Best of luck to you guys!

    TTC since 04/2010
    Ovarian cancer survivor
    DH= low motility
    2/9/11 lap & hysteroscopy- uterine polyp & scar tissue removed
    3/25/11 IUI#1= BFP m/c; D&C at 7w3d (Trisomy 16)
    IUIs #2, #3, #4 and #5= BFNs
    Onto IVF #1= BFN
    FET 4/6/12= 2 extended blasts transferred, with one hatching
    Beta 1= 607; Beta 2= 1,564; Beta 3= 24,439; Beta 4= over 64,000
    First u/s on 5/10= TWINS! Heartbeats 158 and 160!
    It's a boy and a girl!
    Pregnancy Ticker
    My Blog
    Huge congrats to my beautiful BFPB lmj8284, due June 2012!
    "When you get to the end of your rope, tie a knot and hang on." -FDR
  • imageBlueyed228:
    I have no experience with unmedicated or OPK IUI's,  but my RE does my IUI 36-40 hours after ovulation.

    I think you mean after trigger?

    My RE just did my IUI ~28 hours after trigger.  That is my (very well respected) clinic's normal protocol (trigger in the morning, IUI midday the next day), so I'm assuming that the sperm must live longer than 6 hours, given that O supposedly happens around 36 hours post-trigger.  

  • I usually have about 36 hrs in between my trigger shot and IUI, with ovulation being somewhere in there.  As for the sample question, my RE requires that the sample needs to be provided within 2 hrs of the IUI.  Good luck!

    Image and video hosting by TinyPic Lilypie First Birthday tickers Daisypath Anniversary tickers
    TTC #1 since Sept 2010
    DX = Endo and right tube blocked
    IUI #1-3 - 50mg Clomid, 75iu Gonal, Ovidrel, Progesterone = BFN
    IVF #1 - ER = 9R, 9M, 8F; 5DT of 1 embryo (3 frosties) = BFP!!
    Beta #1 (17dpo) = 496, Beta #2 (20dpo) = 1318, Beta #3 (22dpo) = 2190
    EDD Oct 9, 2012
  • My Dr. montinored me with ultrasound and blood to determine when the unmedicated IUIs would happen.  So, i can't answer your question about OPK timing.  However, we have always been told to produce the sample within an hour of our appointment time.  As soon as we get to the office they take the sample and wash it. If your husband needs to prodcue the sample in the AM, i would schedule your appointment for the AM.  Good luck!  
    Aug 11 - Nov11: IUI #1,2,3 & 4 BFN
    Jan 12: IVF #1 - BFP!
    Photobucket BabyFruit Ticker
  • We use donor sperm so i don't have experience with the sperm question but for IUIs (we have had 6 unmedicated/no trigger ones this year) we've tried all combos - same day, next AM, next PM, two days later...all BFNs for us. But i think the best "timed" ones was morning OR afternoon the day following your +OPK. Everyone else on this thread is right - should O 12-36 hour after +OPK.

     

    Hope that helps! GL! 

    Me: 31yrs old. In same/sex relationship for 12years
    I'm carrying & we are using anonymous donor sperm
    In March 2012 diagnosed with Diminished Ovarian Reserve (AMH = O.67) & IVF recommended

    FET (2 5dt embryos) on 11/5/12= BFP! Beta #1=58; Beta #2=98, Beta #3=373. First u/s on 11/28/12 = 1 sac with fetal pole & heartbeat! Next u/s = 12/12/12

    TTC History
    IVF#1 (Antagonist Protocol) Sept 2012 = BFN
    10R; 8F; 4 Day5 GradeA embryos. Put back 2, froze 2.
    12 IUIs (in 9 cycles) since March 2011:
    6 unmedicated/unmonitored = BFNs
    3 with Clomid/Trigger/monitoring/progesterone = BFNs
    "The Spirit of God moves over the formless void, over the darkness and deep, over the surface of the waters. When there is nothing...God is still there."

  • Thanks, everyone! Crossing my fingers and saying prayers like crazy for a miracle!!

    ************ Signature/Ticker Warning ************
    Me (32) DH (36) - Finding our way to baby #1
    Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
    DH: Severe MFI

    12/2/11 - IUI #1- BFN 
    8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

    My ovaries are just for decoration

    12/6/12 - Adopted five embryos that had been frozen for over ten years!
    2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
    2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
    3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

    6/5/13 - Adopted four new embryos that had been frozen for seven years!
     
    9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
    9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
    9/29/13 - m/c @ 5w1d. :(

    11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
    11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
    Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
    6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

    Snowflake baby is a girl! 
    Our beautiful Snowflake girl arrived on July 22, 2014!   
    My embryo adoption blog: Wishing on a Snowflake
     
        image      image 
  • Good luck! 

    And a question for you -- I seem to remember that you are from Austin.  If that is right, can I ask who you are seeing?  I am doing my first unmedicated IUI this cycle, if the timing works out and I am in Austin after I get teh OPK+.  Just curious...

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  • imagebrooklynesque:

    imageBlueyed228:
    I have no experience with unmedicated or OPK IUI's,  but my RE does my IUI 36-40 hours after ovulation.

    I think you mean after trigger?

    My RE just did my IUI ~28 hours after trigger.  That is my (very well respected) clinic's normal protocol (trigger in the morning, IUI midday the next day), so I'm assuming that the sperm must live longer than 6 hours, given that O supposedly happens around 36 hours post-trigger.  

    Yes!  Sorry!

    http://oi58.tinypic.com/nqv6fk.jpg

    DX: PCOS/Recurrent losses/MTHFR mutation (compound hetero)
    5 hysteroscopies/2 surgical
    3 Inject IUIs = 2 m/c's and 1 BFN
    IVF #1= BFP. m/c at 7w6d. Needed 2 D&C's and scar tissue removal. Mild OHSS
    IVF #2 = BFP. Severe OHSS. 4 Drainings. TWINS!
  • I have only done medicated IUIs but in regards to the "sample" I would not try to use it a few hours after it was collected if quality is an issue. I would try to have it down within an hour. 

     

     

    Photobucket TTC since 1999. Unexplained Infertility. IUI#1 Oct. 12/11 - BFN IUI#2 - Nov 8 - Failed
    IUI#3 - Jan 6 IVF#1 -5/18 - stims start (225 gonal f, 75 menopur, 5 lupron) ER 5/29 - 14R, 11M, 7F. 6/1 - Transferred 2 8cell embryos (grade 1 and 2). 8dp3dt +HPT, Beta#1 - 92, Beta #2 - 174, Beta#3 - 614, Beta#4 - 2010. 6wk u/s - TWINS! Baby A 114bpm, Baby B 112 bpm Baby Birthday Ticker Ticker
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