Trouble TTC

PCOS w/ femara vs. clomid...

so i have heard a lot about both clomid and femara and will be starting one of them in december if i get my bfn on thanksgiving. i will be doing iui with it as well and the re said she didnt care one way or the other which medicine i chose, so tell me ladies... do you suggest clomid or femara... thanks for the advice and good luck to you ladies. as always please excuse the post as my phone still hates it when i post on tb.
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Re: PCOS w/ femara vs. clomid...

  • I didn't do very well with either one (also pcos.)  Clomid has more side effects, but most people do try that first.  Honestly, I would get on Met first, for at least a month.  Metformin often makes you respond better to the other meds.  It doesn't mean that you will always ovulate by taking the Met, but it often helps so is worth a try.  I'd get on that first.

    GL

    dx PCOS on Metformin
    LO#1 - 19 cycles, 3 IUIs, 1 m/c, gonal-f, ganirelix, ovidrel, progesterone
    Totally worth the wait!
    Getting ready for #2
    Back on Met, PCOS diet, prepping for treatments 1/12

    Good luck to the wonderful ladies of 3T
    Always cheering on my girls Gymnst1013 & MrsJohns
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  • i need to update my siggy because i actually started met in october and it made me ovulate on my own this month.... i have been on it for approximately six weeks which just shows just how badly i need to update... lol thanks for bringing it up though since met made me ovulate on my own within a month its crazy to think that i have only known about it for a couple months. good luck
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  • If you were able to ovulate with just the Met, then I would suggest Femara first because there are fewer side effects.

    GOOD LUCK!

    dx PCOS on Metformin
    LO#1 - 19 cycles, 3 IUIs, 1 m/c, gonal-f, ganirelix, ovidrel, progesterone
    Totally worth the wait!
    Getting ready for #2
    Back on Met, PCOS diet, prepping for treatments 1/12

    Good luck to the wonderful ladies of 3T
    Always cheering on my girls Gymnst1013 & MrsJohns
    image
    My Chart / Info for Newbies
  • After two cycles of Clomid my uterine lining was shot to helll, so I'm switching to Femara this time around. Apparently, Femara does not have the same negative effect on your lining and CM that Clomid does.

    I have no experience with Femara yet, but from what I understand it might actually be better than Clomid. The reason why most docs turn to Clomid first is because Femara hasn't been approved by the FDA for IF. But my RE says it's been around for a long time and has fewer s/e than Clomid. Based solely on speculation (and my very limited research), I'd probably go for the Femara.

    Whichever direction you choose, I wish you the best of luck!

    me 26 / DH 29
    TTC#1 since 5/2010 (charting, AO)
    2/2011: DX: PCOS, hypothyroid (1700 mg Metformin, 50 mcg Synthroid)
    8/10/2011: First RE appt.
    9/2011 & 10/2011: Clomid + Ovidrel + TI = BFN
    11/2011: Femara + Ovidrel + TI = BFN
    1/2012: Femara + Follistim + Ovidrel + TI = BFP! (Praise the Lord!)
    ?3/23/2012: Graduated from the RE... moving on to a regular OB!?
    ?10/29/2012: Our precious baby boy was born via emergency C-section. 5 lbs, 13 oz; 18" long ?

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  • imageRileyGrace:

    If you were able to ovulate with just the Met, then I would suggest Femara first because there are fewer side effects.

    GOOD LUCK!

    thank you for your suggestions, i was leaning the same way for the same reason but wasnt sure.
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  • imagekaleidoskpeyez:

    After two cycles of Clomid my uterine lining was shot to helll, so I'm switching to Femara this time around. Apparently, Femara does not have the same negative effect on your lining and CM that Clomid does.

    I have no experience with Femara yet, but from what I understand it might actually be better than Clomid. The reason why most docs turn to Clomid first is because Femara hasn't been approved by the FDA for IF. But my RE says it's been around for a long time and has fewer s/e than Clomid. Based solely on speculation (and my very limited research), I'd probably go for the Femara.

    Whichever direction you choose, I wish you the best of luck!

    i am so glad you responded because i was wondering if it had the same effect on the lining and cm, it is really reassuring to hear that is not the case. i have a substanial amount of anectdotal evidence that femara for pcos patients is better but i wanted to check on here with you ladies just in case ... i am thinking i am going to ask for femara. thank you all so much.
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  • I have pcos and did 4rounds of clomid before I knew I had pcos and only ovulated twice. I took the meds at night and didn't have bad side effects but I know lots of ladies do. My close friend did ovulate on clomid but had horrible side effects. She has now done two cycles of femera and hasn't had any side effects.  Good luck which ever one you chose. 
  • Thank you for posting - this is very helpful!

    ______________________________________________________________
    Me 30 <3 DH 30
    Off BCP: Dec 2012
    DX Oct 2013: PCOS
    Testing:  PCOS confirmed / HSG Clear / SA Good!
    Jan 2014: Femara 2.5mg + TI  
    [First treatment cycle.. wish me luck!!]

    All Are Welcome - Feel free to message/PM me about PCOS
    Health Goals:  moving toward low processed sugar/low GI diet, daily vitamins, exercise goal 250 minutes a week (at least 150 high cardio/yoga)... 

  • I did two cycles of Femara and didn't have any kind of response to it; my doctor let me make that decision as well. Everyone's different, though. My RE mentioned less side-effects, etc. and I figured hey, why not. Good luck with whichever way you go.
    Baby Boy Due December 29th!

    Pregnancy Ticker
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