Trouble TTC

Did you respond the same?

Have a question for those of you who have been on clomid on multiple cycles. Did you generally have the same results with how many follices matured? I'm just starting my third cycle all together and my second on 50 mg. Just wondering what to expect. I had one mature follice and almost two other mature ones last time. I just don't wanna see this cycle be cancelled cuz I have too many follices. Thanks in advance.
Diagonsed PCOS TTC since May 2009
First M/C December 2010 Second M/C August 2011
Oct 2011~Second round clomid 50 mg; BFN
Nov 2011~Third round clomid 50 mg: BFP
Dec 11- Beta #1 91;Dec 13- Beta #2 186.2
Dec 27- third miscarriage
May 25th- Beta #1 369;May 27th- Beta #2 798
Baby girl born Jan 23, 9lbs 3oz, 21 1/2" long
May 27th-Beta #1 80; May 29th- Beta #2 304; May 31st- Beta #3 860
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Re: Did you respond the same?

  • I did 50mg all three times.

    Cycle 1 - 2 mature follies

    Cycle 2 - 2 mature follies

    Cycle 3 - 3 mature follies

    So not much difference.

    Started TTC 2/2009
    Started fertility treatments 11/2010
    Ovarian dysfunction, LPD, male factor
    6 failed medicated IUI's
    Pregnant 5/2011 - Miscarriage at 6 weeks due to triploidy
    Decided to adopt - 6/2012
    SURPRISE! Pregnant without intervention - 7/2012 
    Sweet Baby James Born 3/2013
    Decided to be "One and Done"

    ....OR NOT.
    Pregnant 12/2018 despite birth control pills
    Here we go again...
    Due 8/26/19!
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  • I've never taken clomid but I have done 3 rounds of femara. I've noticed that I respond similar but a little slower each time. This last time I still had 3 follies but they were later than normal and almost not mature enough to count. 
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    || 4 years TTC, 2 M/Cs image 4 failed IUIs, 1 failed IVF || 

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  • okay good, thanks ladies. I guess I just had this image of the more clomid you take the more it will work, and I don't want to have to cancel anything!
    Diagonsed PCOS TTC since May 2009
    First M/C December 2010 Second M/C August 2011
    Oct 2011~Second round clomid 50 mg; BFN
    Nov 2011~Third round clomid 50 mg: BFP
    Dec 11- Beta #1 91;Dec 13- Beta #2 186.2
    Dec 27- third miscarriage
    May 25th- Beta #1 369;May 27th- Beta #2 798
    Baby girl born Jan 23, 9lbs 3oz, 21 1/2" long
    May 27th-Beta #1 80; May 29th- Beta #2 304; May 31st- Beta #3 860
    Image and video hosting by TinyPicImage and video hosting by TinyPic
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  • I'm also on femara not clomid, but on the same dosage, I've had 2, 2, and 3 mature follicles.  I don't know if that helps you at all.  But GL on this cycle! 
    TTC with PCOS since November 2009
    IUI#1 Femara/Ovidrel (cd 3-7) = BFP, m/c
    IUI#2 Femara/Ovidrel (cd 5-9) = BFN
    IUI#3 Femara/Ovidrel (cd 3-7) = BFP!
    beta #1 11/23 = 270, P4 = 75
    beta #2 11/28 = 2055
    Our daughter E was born 7/29/2012!
    Surprise, our 2nd daughter P was born 5/22/14!
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  • I know I'm the exception but the more clomid I took the less I responded. Round 1 100- 1 18 Round 2 150- 1 11 then turned to 26 over night Round 3 200- 1 9 cancelled It was obvious that did not respond well to clomid at all. Good luck.
  • Pretty much, all six cycles with 50mg: 4 cycles with 2, 1 with 1 and 1 with 3.
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  • I did two cycles of Clomid (three rounds). The first cycle was perfect, but then I had some problems with the second cycle.

    Clomid 1 (50 mg, CD3-7) - 9mm lining, 1 follie (21 mm) on CD12

    Clomid 2 (50 mg, CD3-7) - thin lining, lots of teeny follies on CD12. Added 100 mg for 5 days (CD12-17). Thinner lining, 2 follies on CD19.

    My RE told me that the more Clomid you take, the worse your lining can get. Obviously this is not the case for everyone, but it was definitely my experience (my lining actually shrank a full mm between CD 12 and 19).

    I know your primary question was about follies, but that changed for me as well. The first cycle I had one perfect follie after 50 mg of Clomid... the second cycle, I needed an extra dose to get two (so obviously I wasn't producing too many, even with extra Clomid). Unfortunately, I think it varies for everyone.

    Here's hoping that this cycle of Clomid has some great results for you!

    me 26 / DH 29
    TTC#1 since 5/2010 (charting, AO)
    2/2011: DX: PCOS, hypothyroid (1700 mg Metformin, 50 mcg Synthroid)
    8/10/2011: First RE appt.
    9/2011 & 10/2011: Clomid + Ovidrel + TI = BFN
    11/2011: Femara + Ovidrel + TI = BFN
    1/2012: Femara + Follistim + Ovidrel + TI = BFP! (Praise the Lord!)
    ?3/23/2012: Graduated from the RE... moving on to a regular OB!?
    ?10/29/2012: Our precious baby boy was born via emergency C-section. 5 lbs, 13 oz; 18" long ?

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  • 1st cycle: 50 mg - 3 follies

    2nd cycle 50mg - no response

    3rd cycle 100mg - 1 follie

    4th cycle 100mg - 1 follie

    So they varied for me a little. GL on this cycle!!

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  • Cycle 1 @ 25mg: 1 follie at 17 went back the next day and it was 19

    Cycle 2 @ 50/25/50/25/50 1 follie at 20

    Cycle 3 @ 50mg 1 follie at 23

    I trigger each cycle with Ovidrel and P4 at 7DPO for cycle 1 and 2 were both 17.

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  • 50 mgs:

    1 follie

    2 follies

    4 follies

    All cycles were back to back. 


    "I prayed for this child and the Lord has granted what I asked of him." ~1 Samuel 1:27
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  • I did clomid 3 different time and got 3 different results.  Even as the dosage increased or changed, sometimes I didn't have as many follicles. 

    Round 1 = 2 follicles

    Round 2 = 3 follicles

    Round 3 = 2 follicles

    *I guess they are all pretty close to one another Stick out tongue

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  • Round 1: 100mg: 2 Follies at 20mm/ Lining at 8mm

    Round 2: 100 mg: u/s on Monday.

    My NP said that she didn't want to see 3 follies, because it could result in multiples.

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  • Thank you ladies, you have eased my worries :)
    Diagonsed PCOS TTC since May 2009
    First M/C December 2010 Second M/C August 2011
    Oct 2011~Second round clomid 50 mg; BFN
    Nov 2011~Third round clomid 50 mg: BFP
    Dec 11- Beta #1 91;Dec 13- Beta #2 186.2
    Dec 27- third miscarriage
    May 25th- Beta #1 369;May 27th- Beta #2 798
    Baby girl born Jan 23, 9lbs 3oz, 21 1/2" long
    May 27th-Beta #1 80; May 29th- Beta #2 304; May 31st- Beta #3 860
    Image and video hosting by TinyPicImage and video hosting by TinyPic
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    Lilypie Second Birthday tickers
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