Have a question for those of you who have been on clomid on multiple cycles. Did you generally have the same results with how many follices matured? I'm just starting my third cycle all together and my second on 50 mg. Just wondering what to expect. I had one mature follice and almost two other mature ones last time. I just don't wanna see this cycle be cancelled cuz I have too many follices. Thanks in advance.
Diagonsed PCOS TTC since May 2009
First M/C December 2010 Second M/C August 2011
Oct 2011~Second round clomid 50 mg; BFN
Nov 2011~Third round clomid 50 mg: BFP
Dec 11- Beta #1 91;Dec 13- Beta #2 186.2
Dec 27- third miscarriage
May 25th- Beta #1 369;May 27th- Beta #2 798
Baby girl born Jan 23, 9lbs 3oz, 21 1/2" long
May 27th-Beta #1 80; May 29th- Beta #2 304; May 31st- Beta #3 860
Re: Did you respond the same?
I did 50mg all three times.
Cycle 1 - 2 mature follies
Cycle 2 - 2 mature follies
Cycle 3 - 3 mature follies
So not much difference.
Started fertility treatments 11/2010
Ovarian dysfunction, LPD, male factor
6 failed medicated IUI's
Pregnant 5/2011 - Miscarriage at 6 weeks due to triploidy
Decided to adopt - 6/2012
SURPRISE! Pregnant without intervention - 7/2012
Sweet Baby James Born 3/2013
Decided to be "One and Done"
....OR NOT.
Pregnant 12/2018 despite birth control pills
Here we go again...
Due 8/26/19!
Oct 2011~Second round clomid 50 mg; BFN
Nov 2011~Third round clomid 50 mg: BFP
Dec 11- Beta #1 91;Dec 13- Beta #2 186.2
Dec 27- third miscarriage
May 25th- Beta #1 369;May 27th- Beta #2 798
Baby girl born Jan 23, 9lbs 3oz, 21 1/2" long
May 27th-Beta #1 80; May 29th- Beta #2 304; May 31st- Beta #3 860
IUI#2 Femara/Ovidrel (cd 5-9) = BFN
IUI#3 Femara/Ovidrel (cd 3-7) = BFP!
beta #1 11/23 = 270, P4 = 75
beta #2 11/28 = 2055
Our daughter E was born 7/29/2012!
Surprise, our 2nd daughter P was born 5/22/14!
I did two cycles of Clomid (three rounds). The first cycle was perfect, but then I had some problems with the second cycle.
Clomid 1 (50 mg, CD3-7) - 9mm lining, 1 follie (21 mm) on CD12
Clomid 2 (50 mg, CD3-7) - thin lining, lots of teeny follies on CD12. Added 100 mg for 5 days (CD12-17). Thinner lining, 2 follies on CD19.
My RE told me that the more Clomid you take, the worse your lining can get. Obviously this is not the case for everyone, but it was definitely my experience (my lining actually shrank a full mm between CD 12 and 19).
I know your primary question was about follies, but that changed for me as well. The first cycle I had one perfect follie after 50 mg of Clomid... the second cycle, I needed an extra dose to get two (so obviously I wasn't producing too many, even with extra Clomid). Unfortunately, I think it varies for everyone.
Here's hoping that this cycle of Clomid has some great results for you!
TTC#1 since 5/2010 (charting, AO)
2/2011: DX: PCOS, hypothyroid (1700 mg Metformin, 50 mcg Synthroid)
8/10/2011: First RE appt.
9/2011 & 10/2011: Clomid + Ovidrel + TI = BFN
11/2011: Femara + Ovidrel + TI = BFN
1/2012: Femara + Follistim + Ovidrel + TI = BFP! (Praise the Lord!)
?3/23/2012: Graduated from the RE... moving on to a regular OB!?
?10/29/2012: Our precious baby boy was born via emergency C-section. 5 lbs, 13 oz; 18" long ?
1st cycle: 50 mg - 3 follies
2nd cycle 50mg - no response
3rd cycle 100mg - 1 follie
4th cycle 100mg - 1 follie
So they varied for me a little. GL on this cycle!!
Cycle 1 @ 25mg: 1 follie at 17 went back the next day and it was 19
Cycle 2 @ 50/25/50/25/50 1 follie at 20
Cycle 3 @ 50mg 1 follie at 23
I trigger each cycle with Ovidrel and P4 at 7DPO for cycle 1 and 2 were both 17.
50 mgs:
1 follie
2 follies
4 follies
All cycles were back to back.
"I prayed for this child and the Lord has granted what I asked of him." ~1 Samuel 1:27
"Whatever it takes, we walk together." ~Pittsburgh Penguins
My IF-turned-baby blog
I did clomid 3 different time and got 3 different results. Even as the dosage increased or changed, sometimes I didn't have as many follicles.
Round 1 = 2 follicles
Round 2 = 3 follicles
Round 3 = 2 follicles
*I guess they are all pretty close to one another
Round 1: 100mg: 2 Follies at 20mm/ Lining at 8mm
Round 2: 100 mg: u/s on Monday.
My NP said that she didn't want to see 3 follies, because it could result in multiples.
Oct 2011~Second round clomid 50 mg; BFN
Nov 2011~Third round clomid 50 mg: BFP
Dec 11- Beta #1 91;Dec 13- Beta #2 186.2
Dec 27- third miscarriage
May 25th- Beta #1 369;May 27th- Beta #2 798
Baby girl born Jan 23, 9lbs 3oz, 21 1/2" long
May 27th-Beta #1 80; May 29th- Beta #2 304; May 31st- Beta #3 860