I just started stims for my first IVF yesterday, and I get the feeling I'm on a pretty entry level dosage for my meds. I am taking 150 iu of follistim and two vials of menopur. I was just curious how that compares to what others are taking, and what the rationale was for various doses.
Re: What is/was your follistim and menopur dosage?
This is a complicated question because some protocols call for a specific cocktail and at different doses at different times. Some clinics have a step down approach, others stim steady. And then on top of all that, your meds can change according to your actual response. Some REs think the extra LH is helpful, others think it is not.
I am AMA. Details in my sig.
300/150 did fine, steady stim
450/150 max meds and got 2 lead follies, steady stim
450/150 w EP max meds, EP to prevent lead follies, steady stim
300/300 new clinic, step down, triggered earlier, best cycle ever
300/300 step down but actually stimmed steady, triggered earlier, worst cycle ever
DX: High FSH/DOR
It took 44 cycles, just over 3 years, 6 failed IUI's in MI, and 1 round of IVF at CCRM to get our BFP!
Beta #1 (9dp5dt) = 206, Beta #2 (11dp5dt) = 438
1st u/s @ 6w5d = 11/11/11 = ONE little bean! HB 120bpm!
?Our Baby Boy Born June 26th, 2012?
Good luck with your cycle!
Me: PCOS DH: Low everything (MFI)
Clomid with TI x 3 2010 BFN
Clomid+IUI+Ovidrel 2010 BFN
IVF w/ICSI #1 2011
9/8/11 Beta #1: 2082!! 9/19/11 Beta#2 34,689!! U/S 9/22/11 HR 127! 11/8/11 HR 150! 12/6/11 HR 136! 12/14/11 HR 139! Born at 26w2d on 2/4/2012! After 83 days in the NICU, Adalyn came home on 4/26/12!
FET 1 3/2013 BFN
FET 2 5/2013 BFN
Me: 36, DH: 42
Dx: DOR and MFI
DH: low count + very low motility; hormones all normal; Sperm DNA Frag. test = poor to fair; male karyotyping normal
Me: FSH 13.4 + AMH 0.26 + hypothyroidism; Scratch the hypothyrodism (?); Blood clotting and immune panel all negative; endometrial biopsy normal
IVF #1 (MDLF - Jul/Aug 2011): BFN (9R, 5M, 3F with ICSI, 3dt of 1 10-cell grade 2, no frosties)
IVF #2 (EP-antagonist - Sep/Oct 2011): BFN (6R, 4M, 3F w/ ICSI, 3dt of 1 6-cell, 1 7-cell, grade 4s, no frosties)
DE IVF #1 (shared cycle - June 2012): c/p (6R, 6F w/ICSI, 3dt 1 8-cell grade A- and 1 7-cell grade A-; no frosties)
DE IVF #2 (shared cycle with new donor - Nov/Dec/ 2012): - BFP!!!!! 12/14/12. U/S on 12/27 shows twins!!!!!
SAIFW/PAIFW
TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
5 IUI's: 2/11 to 6/11 and 1/12= BFN
OE IVF#1-4 8/11-6/12= all BFN
DE IVF#1 11/12 bad embryos= BFN
DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
DE IVF #3 1/14 ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d
DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!
K & K born 11/21/14 at 38wks 4 days
SAIF/PAIF Welcome
http://waitingforraintostop.wordpress.com
300 of menopur (4 vials) and 300 of Gonal F (stims) with either Microdose Lupron (cycle 1) or Ganerelix (cycle 2). I also did BCP (cycle 1) and an Estrogen Patch (cycle 2).
However, I don't think you want to compare your dosage against other people. More is not necessarily better, it is just different. It really depends on your dx and body. I would never want to see someone without a DOR diagnoses taking the dosage of injects that I have been on.
I wasn't necessarily looking to take more, but did want to make sure I am taking enough (would definitely prefer, as would everyone, to only go through this once). I was just curious to get an idea of how they determine which dosage to give people. I find out tomorrow if they are going to adjust my dosage at all, so I know there is room for adjustment. Seeing people's dosages and explanations for it helps me understand why they started me where they did, and I feel more comfortable with it. Thanks for sharing!
IVF #1: 9/11: ER: 12R, 11M, 10F, No Frosties; 5dt: 2 blasts, 1 morula; DD born 6/3/12
IVF #2: 11/12-12/12: ER: 20R, 20M, 16F, 4 Frosties; 5dt: 3 blasts, DS born 8/9/13
If you take too much you likely get lead follies that develop fast and hog all the meds so in the end you get fewer, possibly crappier, mature eggs.
They set your dose based on your hormone levels, your response to meds in the past, especially injectable medications. It can take several tries to come up with a protocol and dosing that is "best" for you if you are a tough case, and this is where experience and an individualized approach can make a difference.
My first two cycles were the exact same dosages as you are on now!
I didn't respond very well (6 eggs first IVF and 4 eggs second IVF), so they upped my dosage this time. I will start on 225 Units of follistim and 3 vials of menopur.
-------------------------
TTC Since 10/2007 with no luck and a 'go with the flow' attitude
1/1010 FINALLY decided to have testing done, dx MFI
7/2010 - DH starts Clomid to increase testosterone and hopefully sperm count
10/2010 - Still low (but improved) sperm count.
11/30/10 - IUI #1 and only = BFN
February 2011 - IVF #1 w/ ICSI =
Chemical PG (Beta 1: 10, Beta 2: 19, Beta 3: 17) :-(
April 2011 - IVF #2 w/ ICSI = BFN :-(
September 2011 - IVF #3 w/ ICSI = BFFN
November 2011 - AMH level tested - .83 (normal for age range)
February 2012 - IVF #4 w/ ICSI = (best response ever yet still) BFFN
April 2012 - DNA testing - NORMAL, RE suggests cycling again with own eggs or using DE
On Break indefinitely...not sure we can afford the emotional and financial roller coaster anymore.
*PAIFW/SAIFW*