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Infertility Veterans
Shady Grove Consult (looong)
I just got back from our consult with Dr. Esposito from Shady Grove. It was very interesting and I think she had some good plans. First we went over all of the paper work from my old clinic, and it turns out they sent a very abbreviated version of my file. Stuff like my HSG report, DH's SA reports and our infectious disease testing results were missing. So I will have to call and hound them to send me those before our next consult with SIRM. We went over all the specifics of my cycles and she said she was impressed with how much I knew that wasn't in the file.
She said that since I am allergic to Lupron we really have no choice but to do the antagonist protocol again. She thinks that I have DOR, which is more than I ever got out of my old RE who never gave me an actual diagnosis. But based off my age, AFC, elevated E2 levels on day 3, and the poor response and fert rates from the IVFs she would bet on me being DOR.
She wants me to re-do all of the Day 3 testing and the HSG since I haven't had one in about two years. She also suggested genetic testing just to be safe.
She wants to put me on their "implantation protocol" Basically I would be on steroids and lovenex starting half way through stimming till 6 weeks of pregnancy. She also wants to play with the ratio of stimming drugs: more menopur and a little less Gonal F. She would do 20,000 units of HCG and do the trigger at 37 hours instead of 36 since my eggs seem to be mostly immature. I asked about DHEA and she said they don't prescribe it but if I wanted to take it she wouldn't stop me.
She also wants to do ICSI on all of my eggs. I told her about what happened with my current RE and the embryologist deciding to not ICSI my eggs last time with out discussing it with us. She said that would not happen here. She assured me that their embryologists are some of the best in the country and they are experts at ICSI.
She also wants me to lose about 30 more pounds, which was already my plan.
I asked her about possibly using my sister as a gestational carrier, her opinion is that the problem really isn't my uterus, that it is my eggs and that if we can just manage to get more good quality embryos from my eggs that we will have a good chance of it working with me.
Overall I felt really good about the appointment and I really liked what Shady Grove has to offer. We have a consult with SIRM in September and hopefully by the end of September we will make a decision about who we are going with and cycle in December or January for the last time.
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Re: Shady Grove Consult (looong)
Sounds like a good appointment! I'm glad you felt really comfortable with the new RE.
Good luck with your appointment with SIRM in September. I think you will have two good option!
~SAIF/PAIF/Everyone Welcome~
Me= 37 and DH = 41
Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)
IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN
IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.
IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132. Lil is here!
TTC#2: Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.
IVF #4: BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN
IVF #5: MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN
IVF #6: (New RE): Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN
FET#1: BFN
After 1 IUI, 3 IVF's with CGH/CCS testing, 10 early miscarriages, and lots of tears and frustration, we are moving on to Domestic Infant Adoption! We are so excited to see what the future holds.
::: Married June 2003:::
TTC #1 since: Aug. 2008
Me: 34, DOR, MTHFR-A1298C (heterozygous), decreased blood flow to uterus, Mild Endo
DH: 38, Balanced translocation 5&10, unexplained MFI, normal SA and SCSA
Tx History: IUI 1&2= BFN
IVF# 1 W/ICSI= BFN
IVF# 2: cancelled d/t no response
IVF# 3= 1 egg retrieved=immature/not viable
IVF# 4= c/p
***CCRM ODWU***
Found DHs BT and Me-decreased blood flow to uterus
Recommended DE IVF w/PGD, incorporate electro-acupuncture. Decided to cycle locally
***New RE***
DE IVF# 1(cycle #6) w/pgd, (freeze all): 30R, 23M, 15F, slow/poor embryo development, 4 biopsied, 1 Normal "Norm"; DE IVF w/PGD, incorporate electro-acupuncture.
IVF# 6: (OE/DS) cancelled
IVF# 7: (OE/DS) 1R, 1M, 1F, arrested day 5
Plan-DE IVF# 2 (cycle #8): DE/DS in May 2015
http://icanhazbabyz.blogspot.com/
IVF#1 Oct 2009 (CCRM) - BFN
IVF#2 March 2010 - Poor response/cancelled
DE IVF#1 Aug 2010 - BFN
DE IVF#2 Dec 2010 - Transferred 1, 2 frozen - BFP!
TTC#2 FET Jan 2013 - Transferred 1 - BFP!
Forever our's October 17th 2012
Dx MFI, AMA, Endo, AMH .16
Lap 10/09 Removed endometrioma, stage IV endo and adhesions
Lap 2/10 Endometrioma cysts & adhesions returned.
Ivf #1 4/10 Antagonist, ET Cancelled.
IVF #2 2/11 A/ACP+E2V C/P
IVF #3 6/11 Letrozole/Antagonist BFN
IVF #4 11/11 Low stim Antagonist BFN
Lap 3/12 Lap & Selective HSG
Many cycles of Letrozole and LP HCG w/TI and LDN
IVF #5 8/12 Low stim BFN
IUI #1 10/12 BFN br> S&PAIFW
It sounds like she knows her stuff and you have confidence in her-that is really important!
Good luck with everything!!
I am glad that you guys got some more clarity from Dr. E. I've heard really good things about her. While you are waiting for your SIRM appointment, are you going to get the lab work done that she suggested?
I forgot about the ICSI drama you had with your last clinic. Reading that p*ssed me off all over again.
DOR is a hard diagnosis to hear, at least it was for me. If you need to talk, let me know. ((hugs))
Off topic here: Um, I found that the story Al did on stink bugs the other day was uber creepy!
So glad it went well.
GL with your next 2nd opinion.
I really hope your next cycle is your BFP cylce.
Worrying does not empty tomorrow of its troubles, It empties today of its strength. ~Corrie ten Boom
Courage doesn't always roar. Sometimes courage is the little voice at the end of the day that says I'll try again tomorrow. ~Mary Anne Radmacher (thank you beadinglady)
It's been a long journey. TTC since 9/06. multiple IUI's and IVF's and 4 m/c's. IVF#3 = BFP, twins, induced at 34w6d due to baby b passing away (no explanation). Delivered on 35w1d, Baby A - baby girl, and Baby B - baby boy, our little angel.
MTHFR A1298C & C677T, Immune Issues and Factor II
It sounds like it went really well! I might be checking out SIRM once they open their Bethlehem office, though it looks like the new schedule at work might prevent me from doing any treatments during the school year, which is a major roadblock...
Keep us posted! Tons of good luck coming your way as you continue the decision making process!
TTC since March 2009 // Me and DH - 28
Testing Summer/Fall 2010 - Unexplained IF
IUIs #1-4 ~ Clomid/Ovidrel/TI/IUI ~ all BFNs
IUI #5 ~ Femara/Ovidrel/TI/IUI ~ BFN
IUIs #6-9 ~ Research Study Meds/Pregnyl/TI/IUI ~ all BFNs
IVF Consultation, More Testing
Diagnostic Cycle ~ Mucinex/Progesterone/TI ~ BFN
IVF #1 ~ Menopur/Bravelle/Ganirelix/Novarel/Progesterone/Lupron
7R, 6F // 2 transferred // 3 frosties ~ BFN
FET #1 ~ Estrace/PIO/Lupron
3 thawed // 2 transferred // 1 lost // no more frosties ~ BFP!!
Beta #1 - 456 // Beta #2 - 1176 // Beta #3 - 2933 // Beta #4 - 6753
EDD: May 16, 2013
Bedrest for SCH // 6w2d through 10w1d
Elevated TSH and Lazy Thyroid DX @ 10w - Started Synthroid
Finally released from RE at 13w
~~ My IF Blog ~~
I'm glad to hear it went well and you got some good info. I was overall very happy with Shady Grove and have recently heard really good things about Dr. E!
GL with you consult with SIRM. And GL with whatever direction you decide to go in from there. I really hope your next cycle is your bfp cycle!
I was wondering when your consult was. I'm glad you had a good experience and it sounds like they have more to offer. When is your consult in Sept with SIRM?