TTC after 35

Can't stop crying today

I feel like such a fool, walking around the house crying. Today I just feel so lost with the current IUI pretty much a useless procedure....We will continue but the b/w was not great says the nurse. 

What should I expect...does anyone have exp. with poor response to stimulation and then changing protocols and improving response. I just feel like I'm grasping at straws and I don't want to believe it is over. Am I wrong in thinking that the response to IVF drugs would be similar if I can't even be stimulated for an IUI? Not that IVF is really an option for us due to $$ or rather the lack of  it.

TTC since 2009 very frustrated 42yr and DH 40

5 cycles of Clomid with satisfactory response=BFN's
Fibroid removal Nov2010
IUI Clomid #1 Feb 2011...BFN..damn it!
IUI Inject's #2 Apr 2011...CANCELLED...low estradiol
IUI Inject's #3 June 2011...BFN
IUI Inject's #4 Sept2011...BFFN
Lap Dec 2011...severe endo..cyst removed..some remains...
IVF#1 Apr 2012 ....cancelled due to over suppression
IVF#2 July 2012....6 follies...only 1 retrieved....BFFN
surgery suggested to move ovary to an better placement but....we moved two time zones away and are financially and emotionally empty

Re: Can't stop crying today

  • I can't tell you what to expect but I did want to send you hugs Left Hug.
    BFP on IVF #2 6/29/2012. Beta #1 7/3 = 522; Beta #2 = 1180; Beta #3 = 6491 image BabyFruit Ticker
  • It only takes 1 egg! You can always change protocols and see if better response. I actually responded better to clomid 100 mg then the injectables. I got 1 follicle one time and 2 the next. It did not work but my RE is hopefull. we are going to IVF though b/c I have high FSH and 1 tube. Good luck. Don't give up!
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  • Don't feel bad! It's perfectly ok to cry it out. It's frustrating news and you're upset.

    I don't have any examples for you, just wanted to say I understand.

    Talk to your RE about changing protocols. Ask if he/she has had patients w/ similar situations and what the outcome has been.

     It's easy to work yourself into a tizzy when you feel desperate and want a solution. But give yourself a day to pull it together, then write down a list of questions and call your doctor. 

    Big hugs for you!

     

    Me = 38, Husband = 31. TTC since 1/10. M/C at 8 wks 5/10. Started trying again 9/10. All tests normal: AMH/MIS, FSH, HSG, SA. Estradoil high. 6/20/11 - Clomid+Ovidrel+IUI#1=BFN. 7/17/11 - Clomid+IUI#2=BFN. 2 natural cycles = BFN. 10/6/11 - Clomid+Ovidrel+IUI#3=BFN. 10/31/11 - Clomid+Ovidrel+IUI#4 = BFN. 11/26/11 - Follistim+Ovidrel+IUI#5 = BFN. IVF#1 - Menopur+Follistim. 2 ET 5/11/12 = BFN.
  • (((Hugs)))
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  • I'm so sorry. I know how frustrating this process can be!
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  • (((hugs)))
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  • No experience to share, but I'm sorry you're having a hard day. Hang in there.
    TTC #1 since June 2010
    Me: 36, DH: 42
    Dx: DOR and MFI

    DH: low count + very low motility; hormones all normal; Sperm DNA Frag. test = poor to fair; male karyotyping normal
    Me: FSH 13.4 + AMH 0.26 + hypothyroidism; Scratch the hypothyrodism (?); Blood clotting and immune panel all negative; endometrial biopsy normal

    IVF #1 (MDLF - Jul/Aug 2011): BFN (9R, 5M, 3F with ICSI, 3dt of 1 10-cell grade 2, no frosties)
    IVF #2 (EP-antagonist - Sep/Oct 2011): BFN (6R, 4M, 3F w/ ICSI, 3dt of 1 6-cell, 1 7-cell, grade 4s, no frosties)
    DE IVF #1 (shared cycle - June 2012): c/p (6R, 6F w/ICSI, 3dt 1 8-cell grade A- and 1 7-cell grade A-; no frosties)
    DE IVF #2 (shared cycle with new donor - Nov/Dec/ 2012): - BFP!!!!! 12/14/12. U/S on 12/27 shows twins!!!!!

    SAIFW/PAIFW
  • I am truly sorry and sending you both hugs and hope...Miracles can happen!
  • I dont' have any experience with it either, but I wanted to send you a hug too!  Left Hug 
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  • I've so been there!!  We had poor response to stims with our first IVF. (Never did IUI, so I have no experience with that) RE sat down with us and told us basically there was nothing else he could do, unless we were willing to do DE or donor embros.  I left the office crying hysterically.  DH was resigned that we were done and would never have children together.  We decided to give IVF another shot---figuring that if we got cancelled again we would have to hang our hats because we are not interesed in DE or embryos.  RE changed protocol (same RE who said he couldn't do anything else) and I responded.  We had 3-4 follicles-2 contained eggs at ER and one was mature and fertilized.  We had transfer, and unfortunately embryo didn't implant this time.  We are meeting with new RE.........as we feel old RE was unencouraging, too quick to cancel our first cycle, and more concerned about his success numbers than what we  want for our family.  We will likely never get a response of more than 5 follicles with stimulation..........but, who cares?-It only takes one!!!!  Good luck!!!!
    TTC since 10/09 Me-43 DH-44 RE and testing 10/10-11/10, Recommending IVF 1/11 New RE AMA and DOR-DH low motility IVF #1.1 cancelled 3/11 due to poor response IVF #1.2 May 2011, one perfect 8-cell embryo, 3dt-BFN, IVF #2.1 Converted to IUI d/t poor response. New RE 9/2011. IVF 2.2 completed using HGH,EPP,DHEA, Q-10 and accupuncture. Transferred one 8-cell, grade one embryo on 10/19. BFP 10/31/11 Chemical pregancy on 11/2/11. Started stims for IVF #3, our final try, on 12-2-11. ET on 12/18. Transferred 3 Grade A embryos-BFFN Planning DE IVF, late March/early April- Donors ER expected to be 4/2-4/4. PAIF/SAIF welcome
  • I don't usually respond here anymore but I saw your post and wanted to say something.  As you can see from my siggy, I now have 2 babies.  I was 40 and 43 at the time so the doctors weren't overly optimistic.  DH also had MFI so we were dealing with his issues as well.  We did 4 IUI's knowing that his sperm levels were so low, there was almost no chance it would work.  Once I started on the meds, it turned out that even when I maxed out on the drugs, I was a horrible responder.  They told me there was nothing more aggressive they could do - but they could just keep tinkering with the meds and see what happens.  A lot of IVF and medicated IUI's is trial and error. They have track records of what works but every person is different.  Sometimes you can take the same drugs 2 months in a row and have totally different results responding. 

    Even with all the tinkering of meds, the most follicles I ever made was 3.   At my e IVF retrievals, they got 5, 6 and 7 eggs.  Other women were complaining they only got 20 or 25.  I cried over my low egg numbers.  But from those numbers, I have 2 kids from 2 pregnancies.  My doctor kept telling me it only takes one.  I would roll my eyes at her and never believed her.  Now I do.  I hope you do too - it really only does take one.  So if you're doing a medicated IUI and are afraid that your numbers aren't great, don't give up home!

    3 IUI's and 2 IVF's later- Brady arrived. Born at 36 weeks after PUPPS and pre-e/HELLP.
    IUI- BFN IVF #1 -BFP! Allie is our 2nd IVF baby. Born at 36 1/2 weeks after pre-e again
    Baby Birthday Ticker Ticker Baby Birthday Ticker Ticker image


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