Infertility Veterans

Question for a friend about PGD on frosties

Can you do PGD (I think that is the right term) or genetic testing on frosties?  My neighbor has six in storage and she was wondering.  I know one of you wise ladies here will know the answer!
Diagnosis: DOR and MFI-low everything IVF #1 = triplets! 2 girls and a boy! Born Sept 29, 2011 at 32w6d due to Pre-e and HELLP syndrome Lilypie First Birthday tickers

Re: Question for a friend about PGD on frosties

  • What day were they frozen on?  We have two day 5 and two day 6 frosties and unfortunately, it isn't an easy process...at least at this point.  We used Reprogenetics in NJ my last two cycles (we're in Dallas) and they usually do a day 3 biospy, PGD on day 4 and have results the morning of Day 5 so that you have transfer on Day 5.  Our frosties are from our very first IVF before we knew about my DH's balanced translocation so we had not done PGD.  Our RE said the only way we could test our frosties right now is to actually fly our embies and myself to NJ for my cycle.  We'd have them thawed and tested the same day and would do transfer right away.  Because of the distance, the turnaround with Day 5 & 6 embies is just too fast.

    HTH!  Good luck to your friend! 

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  • Thanks for the explanation!  I didn't think it could be done and if it could sounds like it would be a big undertaking.  They were frozen on day 6 I believe. 
    Diagnosis: DOR and MFI-low everything IVF #1 = triplets! 2 girls and a boy! Born Sept 29, 2011 at 32w6d due to Pre-e and HELLP syndrome Lilypie First Birthday tickers
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  • Some places do CGH on day 5 blasts (CCRM does this).  At the moment I think the technology for day 5 biopsies normally takes more than same-day to come back, so they might have to thaw, test, and re-freeze.  However, I think I did hear something about same-day testing of day 5 blasts...that might be in the fledgling stages.  She'd probably have to look around for a clinic that would do it.

    TTC in 2008. Stage II/III endo, Hashimotos hypothyroid, low morph (3%).
    2 cycles Clomid/Ovidrel/TI/Crinone=BFN.
    IUI #1 - 4 Follistim/Ovidrel/IUI/Crinone = BFN.
    IVF #1 - Antagonist w/ ICSI 4/10. 17 retrieved, 5DT of 2, BFN :(
    IVF #2 - Long Lupron w/ ICSI 6/10. 15 retrieved, 3DT of 2, BFFN!!
    Lap 7/21/10
    IVF #3 - Clomid/Antagonist w/ ICSI 10/10. 14 retreived, 3DT of 3, BFP 10/20 but m/c. No HB 11/15/10 - D&C 11/17/10.
    FET - 2 blasts, 1 survived the thaw. Transfer 2/19. Beta #1 3/1 375, Beta #2 3/3 885, Beta #3 3/8 4261, Beta #4 3/11 9005. U/S 3/8 1 sac 1 yolk, U/S 3/16 1 heartbeat 114bpm!

     

    James born Oct. 24th 2011 via c-section at 38 weeks!

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    Surprise BFP - Jack born April 28, 2013 via VBAC after PTL at 33 1/2 weeks!

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