Infertility

IVF Med Side Effects

I have not done any IUI's medicated or not so I'm kind of going into this whole IVF thing blind.  I'm hoping someone can shed some insight so I can warn my staff! hahaha

I'll be taking Menopur (300 per injection) and Follistim (150).  Then I'm going to be using Ganirelix for suppression.  PIO (in the AM) and Prometrium (PM) as well as estrogen patches after ET.  I know the prometrium and PIO shouldn't have an y s/e (except pain from the injection site), but what about the rest?

Thanks!!

Our Journey to Brenden

IVF #1: 4/11(Follistim/Menopur/Ganirelix) 10 retrieved/8 mature and all 8 fertilized / 2 embies transferred ... nothing to freeze Beta 5/10 = BFN

IVF Take 2 Long Lupron July 2011

ER 7/3/11 (our 6th anniversary) - 8 retrieved/7 mature/fert ....ET 7/6/11 - 2 beautiful grade A 8 cell embryos

Beta 7/18/11 - 149!!! Beta 7/21/11 - 311 Beta 7/28/11 - 2,000 8/5/11 - Empty Sac 8/8/11 - There's a yolk sac and maybe a heartbeat 8/12/11 - Fetal pole, yolk sac, heartbeat 8/18/11 - Baby looks GREAT!
3 babies waiting on ice


Lilypie Second Birthday tickers


Re: IVF Med Side Effects

  • I have only used it for an IUI and at a lesser dose, but I didn't feel any side effects from Menopur, other than some burning during and right after at the injection site.
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    TTC #1 since 3/09 - DX Hypothyroid, PCOS, MFI
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  • imageKaliChick:

    I have not done any IUI's medicated or not so I'm kind of going into this whole IVF thing blind.  I'm hoping someone can shed some insight so I can warn my staff! hahaha

    I'll be taking Menopur (300 per injection) and Follistim (150).  Then I'm going to be using Ganirelix for suppression.  PIO (in the AM) and Prometrium (PM) as well as estrogen patches after ET.  I know the prometrium and PIO shouldn't have an y s/e (except pain from the injection site), but what about the rest?

    Thanks!!

    I felt tired, hungry and a little more emotional than normal.  When I did PIO shots I had pregnancy symptoms...cramping, sore chest, tired, hungry

    Good luck, hope you are one and done!!

    I am AMA and all tests on H came back normal
    3 failed IVF with OE and 2 failed frozen DE cycles
    Last fresh hail mary DE cycle starting Feb 2013
    PAIF/SAIF always welcome
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  • STL34STL34 member
    imagereb259:
    imageKaliChick:

    I have not done any IUI's medicated or not so I'm kind of going into this whole IVF thing blind.  I'm hoping someone can shed some insight so I can warn my staff! hahaha

    I'll be taking Menopur (300 per injection) and Follistim (150).  Then I'm going to be using Ganirelix for suppression.  PIO (in the AM) and Prometrium (PM) as well as estrogen patches after ET.  I know the prometrium and PIO shouldn't have an y s/e (except pain from the injection site), but what about the rest?

    Thanks!!

    I felt tired, hungry and a little more emotional than normal.  When I did PIO shots I had pregnancy symptoms...cramping, sore chest, tired, hungry

    Good luck, hope you are one and done!!

    This.  With stims I also had some headaches and brain fog (but not as bad as with Lupron).  With PIO I was also constipated.

    That being said, everyone is a bit different!

    imageimage


    ~SAIF/PAIF/Everyone Welcome~ 

    Me= 37 and DH = 41 

    Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)

    IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN

    IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.

    IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132.  Lil is here!

    TTC#2:  Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.

    IVF #4:  BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN

    IVF #5:  MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN

    IVF #6:  (New RE):  Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN

    FET#1:  BFN

  • Thanks, Ladies!!  Sounds like it shouldn't be too bad. 

    STL one of my other friends also warned me about constipation with PIO.

    Our Journey to Brenden

    IVF #1: 4/11(Follistim/Menopur/Ganirelix) 10 retrieved/8 mature and all 8 fertilized / 2 embies transferred ... nothing to freeze Beta 5/10 = BFN

    IVF Take 2 Long Lupron July 2011

    ER 7/3/11 (our 6th anniversary) - 8 retrieved/7 mature/fert ....ET 7/6/11 - 2 beautiful grade A 8 cell embryos

    Beta 7/18/11 - 149!!! Beta 7/21/11 - 311 Beta 7/28/11 - 2,000 8/5/11 - Empty Sac 8/8/11 - There's a yolk sac and maybe a heartbeat 8/12/11 - Fetal pole, yolk sac, heartbeat 8/18/11 - Baby looks GREAT!
    3 babies waiting on ice


    Lilypie Second Birthday tickers


  • I've only done IUI, but I did use Follistim and Menopur.  When you inject the Menopur, do it slowly because it burns a little.  You get used to it after a few times.  As for s/e, mostly pg symptoms (sore breasts, cravings, hungrier, moodier).  I did however have the opposite of constipation so I can't help you in that department.  Good luck! 
    Me: 27, DH: 28 TTC since 11/09
    2/10 & 3/10 Clomid 50mg-BFN
    5/10-Lap Surgery for Stage 2 Endo
    3/11-IUI#1 with Follistim and Menopur-developed mild OHSS= BFN
    6/11-IUI#2 with Follistim -developed moderate OHSS= BFN!
    7/11-FSH-11, AMH 1.6
    9/11-ttc naturally with positive thoughts :)
    10/6/11-POSITIVE pregnancy test!!! 15dpo BETA-220
    6/14/2012- Riley Harper arrived!! We love our little girl
    <a href="http://s532.photobucket.com/albums/ee324/exploshidad/?action=view
  • I was on lupron, menopur, follistim and PIO.  I didn't really have any s/e except for feeling my ovaries during stims -- not really pain, just really aware of them. Oh, and I was very over-emotional about everything!
    IVF #3 = Feb 2012
    beta#1 3/21 (14dp3dt)=413, beta#2 3/23 (16dp3dt)=785, u/s 4/11
    EDD 11/25/12
    **SAIFW** Baby Birthday Ticker Ticker
  • Meds seem to effect everyone differently.. that being sad.. I notice a lot of side effects.

    Headaches, bloating, overall uncomfortableness, forgetfulness, insomnia, moodiness, way more emotional than normal.  The PIO made me hungry and it also made the hair grow on my face a bit more than normal.. fun.. right?

    Hopefully your side effects will be few!! Good luck to you, and your staff!!! Smile

    Renee- 37 DH - Chad - 39
    2/06 - surprise pregnancy - twins
    3/06 - m/c 1st baby at 6 weeks 
    5/06 -2nd baby had no heartbeat at 14 wks.
    D&E - Bled out. Blood transfusions. Week in ICU - Cheated Death!
    Diagnosis: Blood clotting and bleeding disorder, immune issues, & cervical stenosis
    5/10 - 1st IVF cycle - BFN
    FET - 10/12/10 - BFN
    1/11 - IVF with PGD - BFN
    IVF - May - BFN
    6/11 New RE - fingers crossed!
    9/11 - IVF - 4 transferred
    10/13 - BFP!!
    It's a boy! Clint Michael, Due in June!!!

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    Baby Birthday Ticker Ticker





  • Meds do affect everyone differently.  I took Lupron, Menopur, Follistim, Ganirelix, prometrium, and PIO (seseme) in the past and had no side effecs at all.  The Lupron did over -suppress me though.  I also took repronex and had the worst allergic reaction ever.   

    I wish you luck in your cycle.

    TTC since 3/07. IVF#1 = canceled. IVF#2 = 0% fertilization. IVF#3 = BFN. IVF#4 = c/p.  
    Moving forward with Adoption 2017!
  • Other than physically feeling "full" in my ovary area, the last few days I was kind emotional and had crazy cravings!! I use to hate bleu cheese, and now I cannot get enough of it! I also had (and 4 days post ER still have) lower back tenderness so I sleep with a pillow under my knees
    Fraternal twin boys born 1/12/12 at 36 weeks
    Identical twin girls expected in March! 
  • I did also have a touch of insomnia, and it burned while injecting so I went super slow. I only bruised ONCE in all the cycles too!
    Fraternal twin boys born 1/12/12 at 36 weeks
    Identical twin girls expected in March! 
  • I used all the same meds, except for prometrium and estrogen patches. I didn't really notice any mood swings or major s/e. Around day 8 I started to feel the bloat, but nothing too terrible.

    The menopur sucks a little because it has a sting to it. I timed it though, it only lasts about 2 secs though. If you can get through those 2 secs you'll be golden! GL!

    We also glory in our sufferings, because we know that suffering produces perseverance; perseverance, character; and character, hope. And HOPE does not dissappoint.
    Romans 5:3-5

    ~Matt and Jen~
    Married August 26, 2006
    TTC since June 2008
    Severe MFI
    IVF #1 Feb. 2011 = BFN
    IVF #2 (Long Lupron) May 2011 = BFP!!!
    Our sweet little girl, born January 26, 2012

    Time for #2!

    IVF #1 (Long Lupron) July 2013 = BFP!!!

    Beta #1 (8/1) 203! Beta #2 (8/8) 3,677! 1st u/s scheduled for 8/15!

    Lilypie Second Birthday tickers

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  • image1krazykitty:
    Other than physically feeling "full" in my ovary area, the last few days I was kind emotional and had crazy cravings!! I use to hate bleu cheese, and now I cannot get enough of it! I also had (and 4 days post ER still have) lower back tenderness so I sleep with a pillow under my knees

    I completely agree with everything you said.  I remember your post the other day about the bleu cheese.  I am still craving cheese.  I just told my husband, I wish I could just fry up some cheese and dip it in sauce and eat it.  Mozzarella sticks for dinner it is!!

    Me: 27, DH: 28 TTC since 11/09
    2/10 & 3/10 Clomid 50mg-BFN
    5/10-Lap Surgery for Stage 2 Endo
    3/11-IUI#1 with Follistim and Menopur-developed mild OHSS= BFN
    6/11-IUI#2 with Follistim -developed moderate OHSS= BFN!
    7/11-FSH-11, AMH 1.6
    9/11-ttc naturally with positive thoughts :)
    10/6/11-POSITIVE pregnancy test!!! 15dpo BETA-220
    6/14/2012- Riley Harper arrived!! We love our little girl
    <a href="http://s532.photobucket.com/albums/ee324/exploshidad/?action=view
  • Hi K!

    I wanted to add that I forgot that progesterone supps gave me MAJOR constipation.  It was SO awful.  =(   TMI ahead: I became afraid to go #2 at home for fear of clogging our toilet, which would happen when did.  So I'd go to the gym or somewhere with an industrial strength flush.

    Did I really just share that?  lol

    11/10: IUI #1 =100mg Clomid CD4-8 + pregnyl trigger + IUI = chemical pregnancy
    1/11: IUI #2 = 5mg Femara + trigger + IUI = BFN
    2/11: IUI #3 = injectibles + trigger + IUI = BFN
    IVF #1 April 2011 ER 4/23 w/16 eggs retrieved, 14 mature, 11 fert., 4 blasts to freeze, 5dt of 2 blasts on 4/28, beta #1 5/7 = 243... beta #2 5/9 = 491....beta #3 5/11 = 1113!!
    my blog

    2011-02-04_11-37-12_452
    Pregnancy Ticker
  • Oh, D!  This is why I love you! hahahahahahah

    Our Journey to Brenden

    IVF #1: 4/11(Follistim/Menopur/Ganirelix) 10 retrieved/8 mature and all 8 fertilized / 2 embies transferred ... nothing to freeze Beta 5/10 = BFN

    IVF Take 2 Long Lupron July 2011

    ER 7/3/11 (our 6th anniversary) - 8 retrieved/7 mature/fert ....ET 7/6/11 - 2 beautiful grade A 8 cell embryos

    Beta 7/18/11 - 149!!! Beta 7/21/11 - 311 Beta 7/28/11 - 2,000 8/5/11 - Empty Sac 8/8/11 - There's a yolk sac and maybe a heartbeat 8/12/11 - Fetal pole, yolk sac, heartbeat 8/18/11 - Baby looks GREAT!
    3 babies waiting on ice


    Lilypie Second Birthday tickers


  • imageOCW2010:

    Hi K!

    I wanted to add that I forgot that progesterone supps gave me MAJOR constipation.  It was SO awful.  =(   TMI ahead: I became afraid to go #2 at home for fear of clogging our toilet, which would happen when did.  So I'd go to the gym or somewhere with an industrial strength flush.

    Did I really just share that?  lol

     HAHAHAHAHA!!! I *LOVE* that you shared that!!!!!!!

    Renee- 37 DH - Chad - 39
    2/06 - surprise pregnancy - twins
    3/06 - m/c 1st baby at 6 weeks 
    5/06 -2nd baby had no heartbeat at 14 wks.
    D&E - Bled out. Blood transfusions. Week in ICU - Cheated Death!
    Diagnosis: Blood clotting and bleeding disorder, immune issues, & cervical stenosis
    5/10 - 1st IVF cycle - BFN
    FET - 10/12/10 - BFN
    1/11 - IVF with PGD - BFN
    IVF - May - BFN
    6/11 New RE - fingers crossed!
    9/11 - IVF - 4 transferred
    10/13 - BFP!!
    It's a boy! Clint Michael, Due in June!!!

    image
    Baby Birthday Ticker Ticker





  • Please tell me I'm not the only one!  hahaaaa
    11/10: IUI #1 =100mg Clomid CD4-8 + pregnyl trigger + IUI = chemical pregnancy
    1/11: IUI #2 = 5mg Femara + trigger + IUI = BFN
    2/11: IUI #3 = injectibles + trigger + IUI = BFN
    IVF #1 April 2011 ER 4/23 w/16 eggs retrieved, 14 mature, 11 fert., 4 blasts to freeze, 5dt of 2 blasts on 4/28, beta #1 5/7 = 243... beta #2 5/9 = 491....beta #3 5/11 = 1113!!
    my blog

    2011-02-04_11-37-12_452
    Pregnancy Ticker
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