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Progesterone supplements - what to expect?

BzeetyDBzeetyD member
in TTC After a Loss 6 Months+

This is my 2nd cycle on 50mg of Clomid and this week after O, I'll be starting my 1st round of Progesterone supplements (orally, thank you) at 200mg, twice a day.

I know everyone is different but, what can I expect as far as side effects? I've heard they make you crazy tired.

Thanks ladies.

BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08
TTC #1 since 1/10
DX: Unexplained/??? MFI issues

Our lil' lost sparks:
5w3d loss 7/30/10 - EDD March 2011
8w loss 4/15/11 - EDD November 2011
8w3d loss 8/2/12 - EDD March 2013
4w c/p loss 10/29/12 - EDD July 2013

Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
RPL testing all normal, Karyotyping normal

Moving on to IVF.

IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14

After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14
We are so in love with her.

"I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

Everybody is welcome!!!
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Re: Progesterone supplements - what to expect?

  • ColleenS629ColleenS629 member
    I haven't taken them yet, but I hear that the s/e mimic signs of pregnancy. Fun. I'm doing supps this cycle. Yuck. Good Luck!
    m/c 7/17/10
    Dx: MFI- 3% morph
    IUIs: Gonal-F + Ovidrel + b2b IUI= BFNs
    IVF with ICSI= BFP! EDD 11/25/11
    3/18- Beta #1 452! 3/20- Beta #2 1,026!! 3/27- First u/s- TWINS!
    Our twin boys arrived at 36w5d due to IUGR and a growth discordance

    FET: Medicated FET moved up to 5/23 due to ovulation
    Transferred a 6BB hatched blastocyst- genetically normal female embryo
    BFP! 5/28- 5dp6dt      
    6/1 Beta #1- 223! 6/3 Beta #2- 567!

    image

     Be kinder than necessary, for everyone you meet is fighting some kind of battle.
    Report Reply
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  • BzeetyDBzeetyD member
    With all my phantom symptoms every cycle this is just what I need!Tongue Tied I'll let you know how it goes. Good luck to you too!
    BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08
    TTC #1 since 1/10
    DX: Unexplained/??? MFI issues

    Our lil' lost sparks:
    5w3d loss 7/30/10 - EDD March 2011
    8w loss 4/15/11 - EDD November 2011
    8w3d loss 8/2/12 - EDD March 2013
    4w c/p loss 10/29/12 - EDD July 2013

    Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
    RPL testing all normal, Karyotyping normal

    Moving on to IVF.

    IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

    Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
    IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
    FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
    Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14

    After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14
    We are so in love with her.

    "I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

    Everybody is welcome!!!
    Report Reply
  • KristysRedBarnKristysRedBarn
    Taking them orally doesn't bother me much.  They do seem to make me tired, so I take them right before bed.  Taking them vaginally was a totally different story...
    imageimage
    Be kinder than necessary, for everyone you meet is fighting some kind of battle!
    April 2011 CP @ 5 weeks
    Report Reply
  • sunshinenvasunshinenva
    This is my 4th cycle with progesterone.  Lucky you can take them orally...I started out with the vag supositories and after two cycles switched to injections because it caused infections.  The injections have worked great, but yes I am tired, but not to the point it gets in the way of my daily routine.  A cup of coffee helps:)  GL
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  • bbhalphenbbhalphen member
    I took them orally.  They do mimic pregnancy--think sore boobs, discharge.  Other than that, I didn't have a problem.
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