Trouble TTC

Update

We met with RE this morning to discuss past test results that we never rec'd information on and figure out what the game plan is for our next cycle.  The appointment started off just right with us having to wait in our car for 30 minutes, due to the doc being late!

A little background...  DH and I have been TTC for 20 months.  We started seeing RE three months ago and have had medicated cycles of clmoid, progesterone, and 2000 mg of Glumetza.  Diagnosis thus far is PCOS and low progesterone.  I have not responded to the Clomid to their liking over the last three cycles. 

My RE seems to do things differently than most.  For example, he has yet to do an HSG.  I requested it last month, but he told me it was too premature.  In our appointment today, I told him I wanted to go forward with the HSG this month because we did not want to do an IUI prior to doing the HSG. (He has already mentioned IUI last month).  He finally agreed to the HSG today, so I will be doing that soon. 

If the results are OK, he recommended 10 days of Provera to restart my cycle (although I'm unclear as to why).  Then he will increase the Clomid to 200 mg for eight day period instead of four days and also prescribe something he referred to as Dex (to reduce a slightly elevated testosterone level that he found in bloodwork).  When follies are appropriately sized he will have us do our first trigger shot and IUI.

I was a bit surprised that he recommended IUI, since my progesterone was almost where it needed to be last month after ovulation (prior to the progesterone supplements).  He indicated this to be a sign of how well the ovulation went.  I am curious how many medicated cycles you had before IUI?

I am extremely nervous about all of this, but I feel better that we have a plan in place aside from the same routine of the last three months.  I am very glad I have you all to vent to!

Re: Update

  • Good luck this cycle!  The "Dex" is probably dexamethasone.  It is a steroid.  My RE prescribed it during IVF for different reasons, but I have read that it is sometimes used when there are elevated androgens (in your case testosterone).  I am glad you were able to convince your RE to do an HSG, I hope that goes well and no problems are discovered.  I also hope this plans work out for you!

    I haven't done any IUIs.  We went straight from testing to IVF due to our diagnosis.  How many clomid cycles you do before moving to clomid and iui depends on many factors including your DX and your experiences.  It also depends on your RE.  However, you typically are only allowed to do a certain number of clomid cycles period.  Consequently, your RE may not want to wait too long before giving IUIs a shot. 

    imageimage


    ~SAIF/PAIF/Everyone Welcome~ 

    Me= 37 and DH = 41 

    Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)

    IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN

    IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.

    IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132.  Lil is here!

    TTC#2:  Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.

    IVF #4:  BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN

    IVF #5:  MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN

    IVF #6:  (New RE):  Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN

    FET#1:  BFN

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  • It sounds like you have a great plan in place!

    We didn't do any medicated cycles before starting IUI, but that's due to our diagnosis (unexplained IF) and my age (35). So we just jumped right in with medicated IUI's. On another note, I haven't had an HSG either. I've talked to two different RE's about it, and they feel I'm low risk for any tubal problems (no history of STD's, negative chlamydia antibodies, no symptoms of endo) and we are 100% oop. The IUI's are cheaper than the HSG, so we're tyring 3 IUI's before we regroup and decide whether to do the HSG. If we had insurance though, I would have done it before pursuing treatment. It's a bit of a gamble doing IUI's without the HSG, but if it works in 1 or 2 cycles, I come out ahead.

    Good luck with everything!

    Image and video hosting by TinyPic
    TTC #1 since 2009 with unexplained infertility
    IUI#1-4 Jan.-Apr. 2011 = BFNs
    IVF#1 Aug. 2011 = c/p, FET #1 Nov. 2011 = c/p, FET #2 April 2012 = BFP!
    Beta #1 = 153, Beta #2 = 269, Beta #3 = 675
    1st U/S = TWINS!! EDD 12/29/12
    my blog: Journey to Somewhere
    ~~PAIFW/SAIFW~~
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