TTC after 35

IVF might not be in the cards for me (sad)

Pretty sad today.  I wish I knew more about this stuff. IVF doesn't sound like it's in the cards for me b/c I had my first u/s and I only have one follicle developing. The other side is a cyst or endo. I've been on 450 follistim since Friday.  I don't understand it. I had 2 on each side when we did the lower doses for IUI. I'm just scared that I'm all used up. We all worry about egg quality. I forgot about the possibility of lack of quantity. I shouldn't have had my hopes up so high. I'm turning 42 in a few weeks. I feel like I might as well be turning 62. Sorry so down. All those expensive meds down the drain.  Waiting for the call from the doc on what's next.

-Pix

About me: A pixie in the city, 41, TTC #1 since May 2010, married 18 years. Diagnosed with, surgically removed, endometrioma Aug.2010 Sept 2010 IUI #1=BFN, Oct=cyst/bfn, Nov 2010 IUI #2 = bfn. Had to postpone IUI #3 b/c of a cyst natural=BFN. Skipped IUI #3, decided to go for IVF. Found/removed uterine polyps Jan 2011. IVF cancelled, no follicles. IVF #2: 3 great embies put in on Easter Sunday = BFN. Hoping for another chance at IVF in July. TTC is NOT for wimps. http://www.fertilityfriend.com/ticker/2fab90/ttc.png

Re: IVF might not be in the cards for me (sad)

  • pixie ... see my post, looks like we are both having bad days.

    i'm sorry ... 

  • Oh, Pix. My heart goes out to you. Maybe this is just a fluke and next cycle could be totally different? I really hope so. ::Hugs to you::
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  • It seems like a bunch of us in the dumps today.  Maybe the doctor can try diffferent drugs to get more follicles. Did you have your FSH/AMH tested?  Ask them what is.  My "research" this weekend said that different protocols of drugs work better for different women and it is an experiment of sorts to find the right one to stimulate our crappy ovaries. I wish we were all together to get some cocktails today as I can't concentrate at work. This sucks.

    TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
    DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
    5 IUI's: 2/11 to 6/11 and 1/12= BFN
    OE IVF#1-4 8/11-6/12= all BFN
    DE IVF#1 11/12 bad embryos= BFN
    DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
    CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
    DE IVF #3 1/14  ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d

    DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
    First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!

    K & K born 11/21/14 at 38wks 4 days

    imageimage

    SAIF/PAIF Welcome


    http://waitingforraintostop.wordpress.com

  • Oh Pixie =(  I wish I had something to say to make it better. Maybe your docs can recommend something to increase your follicles?  I hope the call you receive is encouraging.  Big hugs.
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  • I'm so sorry - this is emotionally, physically and financially exhausting.  I hope your dr can adjust your meds to increase your response.
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  • I'm sorry Pix, that really sucks. I hope that your doctor can find a protocol that works better for you. Let us know what he/she says.
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    TTC #1 since 4/10, Dx: MFI IVF planned for April/May
  • I'm so sorry Pix. Ditto PP re: other drug cocktails. I know combinations work differently for different folks.
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  • Does anyone know about different combinations?  Has anyone had a low follicle cycle followed by a more normal one?  I just wish I knew if I should have any hope or hang it up, you know? 

    I'm on microlupron 20 ml am and pm, 450 follistim pm, and 2 powders in 1 ml of menopure in the am.  Plus baby aspirin, folic acid, synthroid and prenate vit.

    -Pix

    About me: A pixie in the city, 41, TTC #1 since May 2010, married 18 years. Diagnosed with, surgically removed, endometrioma Aug.2010 Sept 2010 IUI #1=BFN, Oct=cyst/bfn, Nov 2010 IUI #2 = bfn. Had to postpone IUI #3 b/c of a cyst natural=BFN. Skipped IUI #3, decided to go for IVF. Found/removed uterine polyps Jan 2011. IVF cancelled, no follicles. IVF #2: 3 great embies put in on Easter Sunday = BFN. Hoping for another chance at IVF in July. TTC is NOT for wimps. http://www.fertilityfriend.com/ticker/2fab90/ttc.png
  • Pix....that really sucks!!!  We are almost same age-I will be 42 in April.  Have to keep the hope that it's just going to take some different kind of drugs to get you growing more follies.  I often feel much older than 42 too.  Will be watching to see where your doc recommends you go from here.    Hopefully someone has experienced this and can let you know that there can be success after one rough month. 

    TTC since 10/09 Me-43 DH-44 RE and testing 10/10-11/10, Recommending IVF 1/11 New RE AMA and DOR-DH low motility IVF #1.1 cancelled 3/11 due to poor response IVF #1.2 May 2011, one perfect 8-cell embryo, 3dt-BFN, IVF #2.1 Converted to IUI d/t poor response. New RE 9/2011. IVF 2.2 completed using HGH,EPP,DHEA, Q-10 and accupuncture. Transferred one 8-cell, grade one embryo on 10/19. BFP 10/31/11 Chemical pregancy on 11/2/11. Started stims for IVF #3, our final try, on 12-2-11. ET on 12/18. Transferred 3 Grade A embryos-BFFN Planning DE IVF, late March/early April- Donors ER expected to be 4/2-4/4. PAIF/SAIF welcome
  • (((Hugs)))  I know how upsetting news like that can be.  WIll keep you in my T&P.
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  • Pix so sorry for this news.  I have heard of different protocols for different women. My RE also recommended acupuncture to help with egg quality.  Not sure if yours would do the same or not it really seemed to help me though as you can see in my signature.  While I was stimming I went twice a week and the day before egg retrieval and the day of egg transfer.  I then cut back to once a week until my beta draws.  I don't have my doses here with me at work but my protocol sounds very similar to yours.  

    I have no experience on the IVF side but when I was doing all the failed injection cycles for the IUI's every time I had different responses in terms of follie count and they were always making adjustments to my menopur doses.

    GL and hope they have some answers for you,

    JM 


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    IF History in my Bio!

  • RE: JilliansMoma idea on accupuncture -- that's a great idea.  After my own bad news today I called and made a first appointment for next Monday (the first available with the woman who, it turns out, also works directly with and at my fertility clinic, doing on-site accupuncture before/after iui's and ivf).  So, Pix, you might want to ask your doctor if there's anyone they know of in particular before you search on your own for someone.

    Also, my RE has recommended that I start 75 mg/day of DHEA, which you can get cheaply without a prescription at a GNC or other holistic pharmacy.  That recommendation was even before the low AMH news; I didn't pick any up last week but DH has literally just gone out to get me some to start tonight.  I did some Googling and for low ovarian reserve it appears to have a real effect.  Obviously ask your RE first, though.

     

    me - 41 (dx: DOR); DH - 53 (no problems); 7/18/09 - married!; 8/4/09 - BFP on first (real)try; 9/14/09 - missed m/c; 9/15/09 - d&c; 11/09 - 3/10 - 4 natural cycles = BFN; 4/10 - dx hyperthyroidism caused by Graves' disease; 6/10 - thyroidectomy; 7/10 - 12/10 - 1 natural and 5 medicated IUI cycles = BFN; 1/11 - new RE; dx low ovarian reserve (AMH .42; 1/26/11 -- BFP (ectopic) from IUI #6; methotrexate 2/10/11; 6/2/11 - IVF #1 = BFN; 9/12/11 - prescreening for DE; 9/15/11 - IUI #7 (unmedicated)= BFN; 11/8 - begin DE cycle (shared risk program); 12/5 - ER (5 eggs/4 mature/3 fertilized/2 left by day 5) 12/10 - ET of one 1BB blast (expanded, "fair" quality), none to freeze; 12/22 - totally shocked by +hpt; beta #1 = 413; #2 = 3952 2/14 - CVS reveals a healthy baby girl! EDD: 8/27/12 DD born 8/31/12, 10 lbs 10 oz and perfect in every way. 
  • (((Pixie))) I'm so sorry you are going through this! I agree with the PPs about different protocols. Your RE should have some experience and suggestions for you. If he/she doesn't have suggestions, you could always do a consult with another RE to see what they would do.

    Also, there are other boards here on The Bump that might have a broader range of experience. Do you post on either Trouble Trying to Conceive? Or Infertility? I post on TTtC and know that a lot of them have experience, or have seen others go through challenges like this.

    So sorry, I know this is a lot to process. Everyone gave such great advice and we are all rooting for you!!! Big Hugs!

    image

  • Pixie,

    I don't have any good words of advice, as I have not started our IVF yet, but I just wanted to let you know you're in my T&P.  Big ((hugs)) to you. 

    m/c at 6 wks 2002
    Endometriosis, s/p lap 2009
    Behcet's disease, s/p partial vulvectomy 2010
    Started bromocriptine to lower prolactin level 2010
    Clear HSG 11/2010 :)
    DH morphology = 4, rest of SA looked good 01/2011
    02/2011 First Clomid 50mg cycle
    BFP 03/02/2011
    No heartbeat at 10w5d 04/18/2011; D&C 04/23/2011
    07/2011 Second Clomid 50mg cycle, BFN
    08/2011 Third Clomid 50mg cycle, BFN
    10/2011 First Clomid 100mg cycle with Ovidrel trigger = BFN
    11/2011 Second Clomid 100mg cycle with Ovidrel trigger = BFN
    12/2011 Third Clomid 100mg cycle with Ovidrel trigger = BFFN
    01/2012 Fourth Clomid 100mg cycle with Ovidrel trigger = ?
    Lilypie Angel and Memorial tickers
  • Sending you a PM : (
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  • Hang in there Pix, maybe there is a different drug you would respond better to. I also know someone who only had one fertilized egg and they put it in and it stuck. Also check with your Dr office to see if there are any patients with left over meds. My second cycle I bought all of mine from other patients and saved $1100. Also check on one of the message boards there is someone who takes donated meds and distributes them to those in need.
    Baby Birthday Ticker Ticker
  • Everyone thanks sooo much for all your comments and support.  I really means a lot.  I'm going to try another IVF soon.  I am hopeful that the DHEA will make some difference.  And I'm going to ask not to do the bcps if possible.  I've decided not to do acupuncture.  I had 2 "good" IUIs (I use good loosely as they were both bfns) with 4 follies each before I tried acupuncture.  Then I did an acupuncture session and now I have zero follies for IVF.  I'm putting two things together that are probably unrelated but this is a mental game too.  Good luck everyone!  bfps for all of us very soon.

     

    About me: A pixie in the city, 41, TTC #1 since May 2010, married 18 years. Diagnosed with, surgically removed, endometrioma Aug.2010 Sept 2010 IUI #1=BFN, Oct=cyst/bfn, Nov 2010 IUI #2 = bfn. Had to postpone IUI #3 b/c of a cyst natural=BFN. Skipped IUI #3, decided to go for IVF. Found/removed uterine polyps Jan 2011. IVF cancelled, no follicles. IVF #2: 3 great embies put in on Easter Sunday = BFN. Hoping for another chance at IVF in July. TTC is NOT for wimps. http://www.fertilityfriend.com/ticker/2fab90/ttc.png
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