XP: Anyone taking Estradiol under RX by RE?

krayola99

Hi Ladies,

Sorry for the lack of intro - I'm coming over from 1st Tri with this question, cause I think you ladies might have some more experience with this.

I was prescribed Estradiol while on a Femara cycle cause when I was gearing up to O, the u/s showed that my follies were maturing, but my lining was falling behind.  So the Estradiol sped up my lining and I guess I got PG.  However, now I'm reading all this stuff about Estradiol being in Category X, and it's freaking me out.  I'm going to ask my RE about it today (I go into the office in a couple of hours), but I just wanted to see if any of the other PAIF girls had any experience with this. My RE has said to keep taking it until 10 weeks.  However, the bottle says "do not use this medicine if you are pregnant or plan to become pregnant".   Google has revealed that Estradiol is a contraindicator for pregnancy, which may result in birth defects or cancer later in the child's life.  Any reason why the RE would keep me on this?  Can't help but freak out about it.  Any thoughts would be greatly appreciated.  Thanks in advance!

BRSaugust20

I was on Estrace (generic of estradiol) until I hit 12 weeks - everything is fine with the baby. Plenty of women require it and it is routinely prescribed by REs. 

Anyone who does an frozen transfer from IVF would need artificial estrogen and progesterone because they wouldn't have a corpus luteum cyst to create it naturally. 

 

krayola99

Thanks BRS.  That makes me feel a little better.  Sometimes, Google is REALLY not my friend!

GenRN45

Stay away from google.

I was also on it (2mg twice a day) until 12 weeks.

mrsolsenk12

I was on estrace until 12 weeks and it was fine. I got freaked out when I read the booklet that came with it that said "don't take when pregnant" but I figured if my RE gave it to me then it was safe. As you can see, my son is 14 months and healthy.

krayola99

Thanks for your posts everyone! Update after speaking with RE: Since I have PCOS and they were concerned about my lining, the RE said that I need to stay on Prometrium and Estradiol in order to ensure that my lining is stable and reduce chances of m/c.  She recommends staying on it until wk 10, so that they can feel more confident that the baby is being well supported by the placenta instead of just the lining.  She also said that the risk of birth defects and other issues comes with prolonged use of estradiol later in the pregnancy after the sexual organs have begun to develop, so taking it through the 1st tri is safe.  Phew!!  Thanks for your support ladies!  I feel much better now.  Google + wild imagination of a pregnant lady = not so good.  Hope this info helps you too

nwarner324

Thanks for posting this.  I thought the same thing but figured since the doc told me to take it then it was ok.  Reading all this def makes me feel better.  My RE also told me that I can stop at 10 weeks.