*MZANS*

NYC1216

 Hey I reposted my post because I wasnt sure if you would see it below.  I saw your post about your fertility report.  My last cycle, I was devestated because of 19 follies, I had 16 mature and only 7 fertilized.  This was such a poor fertilization rate and my Dr told me I had a problem with my egg quality.  I was crying for days so I know how you feel.  Keep your head up.  You have 6 embryos and I have seen many girls get pregnant with half the amount.

Just had a few questions for you that may reveal some answers for you as to possibly why not more were mature. 

First, if you are PCO, then those patients notoriously have more immature eggs.

Why did your RE not suppress you  at all with BCP or Lupron?

Were you on an antagonist protocol? 

 I wonder if your RE triggered you too early. What was your E2 and follicle sizes before trigger? He/She may have been nervous about OHSS and triggered you a bit early.

Sometimes it just helps the pain a bit to understand the cycle a bit more.

MZANS

Hi!  My RE never diagnosed me as PCOS but I have a feeling he will now.  I always had a high antral follie count and I did always question it.  He just told me I had healthy ovaries.

I did do antagonist protocol.  No supression, gonal F, Guarenelix and Low Dose LH.  I triggered when my lead was 24 and the range was 24-15.

My E2 was 3500 the day before trigger.  I am devistated about the high number of immature eggs.  

What do you think of all this? 

NYC1216

It seems like they were within the normal range for trigger.  I do not have PCOS, but based on my ovaries, I have PCO.  I also do not have regular cycles.

Its possible that the antagonist was just not great for you.  I dont think it was good for me, but will have a better idea after I see the results of my next cycle.

I hope you have success with this cycle, but if not, I would not do antagonist again.

It sucks how this is all so trial and error.  I have learned a lot about my hormones though and have a feeling that I need minimal LH.  In antagonist, the LH is not turned off until ganirelex is added, which is sometimes too late.

MZANS

I have a few questions..

What is the difference between PCOS and PCO?

What protocol are you doing this time?

Can you explain the minimal LH thing to me?  

Thanks so much! 

NYC1216

The syndrome includes things such as elevated testosterone, high insulin level, hirtuism ect.  I dont have any of that.  I just have lot of cysts/follicles on my ovaries.

I am doing an estrogen priming protocol now.  

Basically girls with pco tend to have higher LH levels to begin with.  High LH levels during stimulation can ruin egg quality.  Therefore, antagonist is not always great for PCO since the pituitary system/LH is never shut off until ganirelex is added.