Infertility

Lovenox as part of IVF protocol?

My RE had me start Lovenox injections as part of my IVF protocol.  Is this typical?  My previous RE said I would start with it when/if I got KU, but I never heard of starting it on day 3 until I started with a new RE (my doc left the practice so I got a sub).  Has anyone else done this?
4/08 BFP resulted in m/c
8/08 BFP resulted in m/c
3/09 Polyp removed and dx MTHFR (both copies)
6 Clomid cycles, all BFN
5/09 IUI#1 with Clomid=BFN
6/09 IUI#2 with Clomid=BFN
8/09 IUI#3 with Clomid=BFN
IVF#1 = BFN
IVF#2 = BFN
IVF#3 ET 2 Grade A blasts 11/16/11
Beta #1: 485
Beta #2: 2,495
Lilypie First Birthday tickersimage
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Re: Lovenox as part of IVF protocol?

  • c1311c1311 member
    I took it during my fresh cycle and FET.  I tested positive for antiphospholipid antibodies (clotting disorder associated with endometriosis), so was on it from the start of stims through my miscarriage/negative FET.  Do you have a clotting disorder?  I think some clotting disorders don't require treatment until a positive pregnancy test and others are better treated from the start of stims.
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  • imagec1311:
    I took it during my fresh cycle and FET.  I tested positive for antiphospholipid antibodies (clotting disorder associated with endometriosis), so was on it from the start of stims through my miscarriage/negative FET.  Do you have a clotting disorder?  I think some clotting disorders don't require treatment until a positive pregnancy test and others are better treated from the start of stims.

    Yes, I was diagnosed with both copies of MTHFR.

    4/08 BFP resulted in m/c
    8/08 BFP resulted in m/c
    3/09 Polyp removed and dx MTHFR (both copies)
    6 Clomid cycles, all BFN
    5/09 IUI#1 with Clomid=BFN
    6/09 IUI#2 with Clomid=BFN
    8/09 IUI#3 with Clomid=BFN
    IVF#1 = BFN
    IVF#2 = BFN
    IVF#3 ET 2 Grade A blasts 11/16/11
    Beta #1: 485
    Beta #2: 2,495
    Lilypie First Birthday tickersimage
    imageimageimage
  • I did too starting at CD 3 on my IVF cycle. I have the APA Annexin V
    May 06: Natural PG= m/c, July 09: TI= m/c, November 09: TI=BFN, December 09: IUI= c/p
    IVF#1: start stims 1/26; ER 2/8; ET 2/13= BFN; FET#1: May 2010= m/c *NEW CLINIC Jan 2011* IVF#2: start stims 1/12; ER 1/22; ET 1/27= BFN; IVF#3: TBD
    ~SAIFW/PAIFW~
  • I did due to my MTHFR diagnosis.
    TTC since 8/07 DX - Severe MFI/azoospermia & MTHFR/ TESEs found sperm - 7/08 & 6/09/ 12/08 - IVF#1 - BFN/ 6/09 - IVF #2 - cancelled due to OHSS risk (had retrieval)/ 7/09 - FET #1 - BFN/ 9/09 - FET #2 - BFN/ 11/09 - IVF #3 with new RE cancelled twice - 10/09 & 11/09/ 1/10 - IVF #3 take 3 - BFN/ 4/10 - IVF #4 - first ever BFP on 5/13/10!!! 108 @ 10dp3dt/ 2nd beta 311!/ sono on 5/28/10 said TWINS!!!! Lilypie Second Birthday tickers
  • After MC's and CP's my RE had me start taking it with my last IUI. I didnt know I had a clotting disorder until I had BW done when I went to the ER with a DVT. My OB had done BW and said everything was fine. as far as Im concerned it cant really hurt, can help. You just have to be careful on it, if you cut yourself you will bleed - a lot, and you bruise easily on it. My body is covered with dog toenail bruises. That paired with the weight gain, bloat and circle of bruises around the bellybutton, Im a real sight!
    1-20-09 BFP third month of Follistim IUI 02-19-09 MC 06-24-09 MC July IUI Follistim Ganirelix Ovidrel Crinone=BFN Aug. IUI Follistim Ganirelix ovidrel Crinone=BFP= scared sh**less 10-12-09 MC = 1 ectopic 1 perfect Dec. IUI Gonal-F Ganirelix Ovidrel Crinone Lovenox 01-02-10 BFP=scared sh**less again 01-06-10 CP SAIF ALWAYS WELCOME : ) March 2010 - IVF in progress converted to IUI 03-30-10 BFN April 2010 - IVF - BFFN June 2010 - IVF - BFFN July IUI BFP! March 26 2011 Gracie is here! imageImage and video hosting by TinyPic imageImage and video hosting by TinyPic
  • I think I started mine the day after my egg retrieval and have been on it every day since.
  • I'm homozygous for Factor V Leiden and heterozygous for MTHFR.  My old RE had me start Lovenox the day after ER.  My new RE is much more cautious and had me start it with my stims, then take a 2 day break right before and after ER.  

    I'll be on a blood thinner until 8 wks post partum (Lovenox until about 33w, Heparin until delivery, and likely Coumadin after delivery).  In fact, my peri more than doubled my dose from 40 mg 1x/day to 50 mg 2x/day because of my FVL.  


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