Infertility

Come in if you've done PIO injections...

Did any of you had any problems filling the syringe?  When I tried to draw up the medicine, hardly anything came out.  Then, when I pulled the plunger back, the plunger would go forward when I let it go.  It's hard to explain, but it was such a pain.  Anyone else have issues like that?
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Re: Come in if you've done PIO injections...

  • My RE said that we could put the bottle of PIO in a warm glass of water. This will make the oil less thick and able to pull into the syringe better.

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  • I'd roll the vial in my hands or put it in a pocket for a few minutes to warm it up.  It's really thick stuff so you have to draw up slowly, even if you warm it 1st.

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  • are you using the big huge needle to draw and then changing it to inject?
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  • There might be a small bubble in the needle part... sit the vial on your counter, pull plunger to 1 cc, insert needle into vial and push the plunger in. Pick the vial back up and try to pull back then... hopefully you just have a small air bubble in there.

    If that doesn't work, get out a new needle and try it again... good luck!

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  • imageSue&Pasquale:
    are you using the big huge needle to draw and then changing it to inject?

    I'm wondering that too. . . .

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  • Thanks for the advice about warming it.  Hopefully that will help!

    imageSue&Pasquale:
    are you using the big huge needle to draw and then changing it to inject?

    Yeah, I'm using the big needle, which, to make matters worse on my first try, I couldn't unscrew the large needle, so I had to try it all over again with another syringe.  *sigh*

    TTC since Jan. 07
    6 IUIs,IVF #1 w/ICSI = BFP!
    Betas, 332 & 856 = twins!

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  • Oh, one more thing...  the PIO needles I got had a tendency of not being screwed together tightly.  I got into the habit of giving the needle/syringe connection a check before drawing up.

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  • I use the biggest needles I've got (I think they are 17guage) and then switch the needle to a smaller one for injecting.  That helps.

    Warming it up helps too.  I run the faucet until it gets really hot, then let the bottle sit in there for a good 5 minutes.

    GL!

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  • We had a major freak out on our first night because it was causing us the same exact problem!!

    But we learned that if there is a bubble it will not work so we kept trying it over and over and it usually took us a couple of times of trying to fill up the syringe.  

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  • Are you injecting 1cc (or whatever amount you're pulling out) of air into the vial? If not, you're essentially trying to pull from one vacuum into another, which may be why you're getting resistance. It would also explain why the plunger is getting pulled back up. GL!
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  • I would turn on the sink as hot as the water would go and let the hot water run over the vial of PIO for a few minutes.  You'd be surprised how thin the meds would be after that!
  • Looks like you got some good advice already but this is what I do:

    warm the vial under water

    draw the needle back and push the air into the vial, this should help with resistance

     it is a little hard to draw up every time, and I agree with the pp to check the needle out and make sure it's big enough, once I accidentally grabbed one of the trigger shot needles and its a lot smaller, there was definitely a difference...

    Good Luck

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