How could I have low E2 on Day 8 of stims????

mrs.cb

Yesterday was Day 8 of stims for me on IVF #1.  I have PCOS, so I think my doctor might have oversuppressed me...what do you think?

My E2 and follice numbers:

1st check up:  E2 was 77, all follicles unnder 9

2nd check up:  E2 117, 5 follicle on left ovary (10-13mm), 4 follicle on right ovary (10-11mm)

3rd check up:  E2 277, 6 follicles on left (10-13mm), 4 on right (7-12mm)

 They upped my doses to 20u Lupron (it has been this unit for the whole cycle), 150 Gonal F and 75 Menopur.

I was scheduled for ER on 1/19, but I think that'll be pushed back.  This sucks.  Do you think they'll cancel my cycle???

jhleap

Your E2 is still rising, so I think you are ok. My E2 was about 300 on day 7 of stims (and 5 small follies), and then day 9 it shot up to 800( 7 follies, none above 13mm), today day 11 of stims... it was 1750 (11 follies - largest is 20mm - smallest is 11mm).

They may push you back but it depends on the growth of the follies.

My RE does not cancel a cycle for low E2 unless it is below 300 at trigger. Remember that it does go up after trigger as well.

Dragonfly1226

I don't think your cycle will be cancelled. It sounds like you are progressing.

Good luck  

ashlyrose

I don't know how far apart your checkups are but my RE said E2 levels should double in 2 days. I agree that your E2 is rising which is good. Maybe increasing the dosage will help. 

Bride2Be2008PA

I had low E2 on day 8 and it actually started dropping from there on 150iu of Gonal. I have PCOS as well. We were doing a TI cycle, so I ended up being cancelled, but I think as long as you are still going up you'll be okay. I agree with pp, maybe they should be increasing your dosage. Good luck.

iwannababy2010

ashlyrose:

I don't know how far apart your checkups are but my RE said E2 levels should double in 2 days. I agree that your E2 is rising which is good. Maybe increasing the dosage will help. 

This.  I have low, but doubling E2 numbers, the nurse said that as long as they are progressing (doubling) things are good.  I upped my Menapur and lowered my Lupron.